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Nature Methods, ISSN 1548-7091, 05/2009, Volume 6, Issue 5, pp. 363 - 369
Induced pluripotent stem cells (iPSCs) have been generated from somatic cells by transgenic expression of Oct4 (Pou5f1), Sox2, Klf4 and Myc. A major difficulty... 
DEFINED FACTORS | BIOCHEMICAL RESEARCH METHODS | DYSPLASIA | HUMAN FIBROBLASTS | KERATINOCYTES | INDUCTION | DIFFERENTIATION | HUMAN SOMATIC-CELLS | EFFICIENT | EXPRESSION | VECTORS | RNA-Binding Proteins - genetics | Gene Expression - genetics | Homeodomain Proteins - metabolism | Humans | Alkaline Phosphatase - metabolism | Valproic Acid - pharmacology | Embryo, Mammalian - metabolism | SOXB1 Transcription Factors - metabolism | Moths - genetics | Octamer Transcription Factor-3 - genetics | Chimera - embryology | Transfection | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Transposases - genetics | DNA Transposable Elements - genetics | Transgenes | Cell Differentiation - physiology | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Cell Dedifferentiation - drug effects | Repressor Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Genetic Vectors - genetics | Pluripotent Stem Cells - metabolism | Teratoma - pathology | Animals | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - transplantation | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Cell Dedifferentiation - genetics | Chimera - metabolism | Kruppel-Like Transcription Factors - genetics | RNA-Binding Proteins - metabolism | Physiological aspects | Transposons | Nuclear reprogramming | Research | Gene expression | Genetic engineering | Rodents | Research methodology | Stem cells | Index Medicus
Journal Article
Nature Biotechnology, ISSN 1087-0156, 06/2004, Volume 22, Issue 6, pp. 695 - 700
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 121, Issue 7, pp. 1005 - 1016
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 12/2015, Volume 44, Issue 5, pp. 2214 - 2226
Journal Article
Science, ISSN 0036-8075, 11/2007, Volume 318, Issue 5854, pp. 1302 - 1305
Journal Article
Developmental Cell, ISSN 1534-5807, 10/2011, Volume 21, Issue 4, pp. 694 - 707
Journal Article
BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 10/2016, Volume 1859, Issue 10, pp. 1289 - 1298
Dedifferentiation, that is, the acquisition of stem cell-like state, commonly induced by stress ( , protoplasting), is characterized by open chromatin... 
TAG1 | Dedifferentiation | Decrease in DNA methylation 1 (DDM1) | Protoplasts | DNA methylation | Chromomethylase3 (CMT3) | Transposable elements | SUBNUCLEAR LOCALIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | STRESS-RESPONSE | TISSUE-CULTURE | BINDING DOMAIN | PLANT-CELLS | HISTONE METHYLATION | BIOPHYSICS | MESOPHYLL PROTOPLASTS | SOMACLONAL VARIATION | NON-CG METHYLATION | Cell Dedifferentiation | Green Fluorescent Proteins - genetics | Recombinant Fusion Proteins - metabolism | Arabidopsis Proteins - metabolism | DNA-Binding Proteins - metabolism | Protoplasts - metabolism | DNA Methylation | Transposases - genetics | Gene Expression Regulation, Plant | Transcription, Genetic | Genes, Reporter | Transformation, Genetic | Green Fluorescent Proteins - metabolism | Arabidopsis Proteins - genetics | Plant Cells - metabolism | Transposases - metabolism | Arabidopsis - cytology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA Transposable Elements | Plant Leaves - cytology | Arabidopsis - metabolism | DNA-Cytosine Methylases - genetics | Arabidopsis - genetics | Transcription Factors - metabolism | Histones - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Recombinant Fusion Proteins - genetics | Histones - metabolism | DNA-Cytosine Methylases - metabolism | Arabidopsis thaliana | Chromatin | Transposons | Genetic transcription | Methylation | Stem cells
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2015, Volume 112, Issue 6, pp. E536 - E545
BRAF (v-raf murine sarcoma viral oncogene homolog B) inhibitors elicit a transient anti-tumor response in ∼80% of -mutant melanoma patients that almost... 
Drug resistance | Mouse models | BRAF inhibitors | Melanoma | mouse models | melanoma | drug resistance | MUTAGENESIS | MULTIDISCIPLINARY SCIENCES | KINASE | ACQUIRED-RESISTANCE | MITF | CELL-SURVIVAL | CONFERS RESISTANCE | BAD PHOSPHORYLATION | EXPRESSED RAS ERAS | LINEAGE SURVIVAL | MUTATIONS | Immunohistochemistry | Blotting, Southern | Embryonic Stem Cells - metabolism | Humans | Oncogene Protein p21(ras) - metabolism | bcl-Associated Death Protein - metabolism | Indoles - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Melanoma - metabolism | Genetic Association Studies | Transposases - metabolism | Animals, Genetically Modified | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Sequence Analysis, DNA | Blotting, Western | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | Exome - genetics | Animals | Mutagenesis | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Signal Transduction - physiology | Mice | Drug Resistance, Neoplasm - physiology | Dosage and administration | Enzyme inhibitors | Drug therapy | Observations | Models | Mutation | Gene expression | Rodents | Index Medicus | Biological Sciences | PNAS Plus
Journal Article