X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (9791) 9791
Newsletter (49) 49
Book Chapter (29) 29
Conference Proceeding (5) 5
Dissertation (4) 4
Magazine Article (4) 4
Publication (3) 3
Book / eBook (1) 1
Reference (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (6905) 6905
life sciences & biomedicine (6493) 6493
humans (5323) 5323
triazoles - pharmacology (5025) 5025
animals (4400) 4400
male (3108) 3108
female (2665) 2665
pharmacology & pharmacy (1994) 1994
triazoles - therapeutic use (1798) 1798
rats (1697) 1697
triazoles - chemistry (1596) 1596
mice (1448) 1448
triazoles (1292) 1292
triazoles - administration & dosage (1192) 1192
middle aged (1100) 1100
dose-response relationship, drug (1037) 1037
adult (1025) 1025
triazoles - metabolism (962) 962
biochemistry & molecular biology (937) 937
oncology (902) 902
triazoles - pharmacokinetics (886) 886
analysis (874) 874
structure-activity relationship (796) 796
cell line, tumor (765) 765
chemistry (740) 740
azepines - pharmacology (735) 735
triazoles - adverse effects (725) 725
aged (699) 699
triazoles - chemical synthesis (686) 686
physical sciences (685) 685
endocrinology & metabolism (655) 655
breast neoplasms - drug therapy (585) 585
treatment outcome (585) 585
nitriles - therapeutic use (577) 577
rats, sprague-dawley (556) 556
sitagliptin phosphate (554) 554
molecular structure (535) 535
enzyme inhibitors - pharmacology (532) 532
research (527) 527
voriconazole (524) 524
pyrimidines - pharmacology (519) 519
time factors (519) 519
microbiology (506) 506
nitriles - pharmacology (496) 496
breast cancer (474) 474
toxicology (474) 474
triazoles - toxicity (470) 470
cell proliferation - drug effects (464) 464
cell biology (456) 456
cancer (452) 452
antineoplastic agents - pharmacology (451) 451
physiological aspects (446) 446
chemistry, medicinal (444) 444
kinetics (441) 441
rats, wistar (440) 440
cells, cultured (436) 436
in vitro techniques (431) 431
care and treatment (425) 425
antifungal agents - pharmacology (402) 402
drug interactions (395) 395
disease models, animal (392) 392
proteins (392) 392
administration, oral (391) 391
models, molecular (388) 388
gene expression (382) 382
diabetes mellitus, type 2 - drug therapy (376) 376
cell line (372) 372
research article (369) 369
abridged index medicus (368) 368
health aspects (364) 364
neurosciences & neurology (354) 354
apoptosis - drug effects (349) 349
drug therapy (347) 347
triazole (345) 345
binding sites (344) 344
neurosciences (344) 344
protein binding (344) 344
enzymes (331) 331
aromatase inhibitors (329) 329
letrozole (328) 328
breast neoplasms - metabolism (325) 325
antifungal agents - therapeutic use (323) 323
mice, inbred c57bl (313) 313
apoptosis (312) 312
pyrazines - therapeutic use (311) 311
nitriles - administration & dosage (310) 310
drug therapy, combination (308) 308
adolescent (305) 305
medicine & public health (305) 305
drug design (301) 301
environmental sciences (300) 300
environmental sciences & ecology (298) 298
antifungal agents - pharmacokinetics (294) 294
triazoles - blood (292) 292
pharmacology (289) 289
aromatase inhibitors - therapeutic use (287) 287
mutation (286) 286
infectious diseases (284) 284
science & technology - other topics (280) 280
microbial sensitivity tests (279) 279
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (9755) 9755
Japanese (83) 83
German (75) 75
Chinese (42) 42
Russian (36) 36
French (21) 21
Spanish (11) 11
Portuguese (9) 9
Hungarian (7) 7
Dutch (6) 6
Ukrainian (5) 5
Italian (4) 4
Croatian (2) 2
Polish (2) 2
Arabic (1) 1
Czech (1) 1
Slovenian (1) 1
Swedish (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Biochimica et biophysica acta. Molecular cell research, ISSN 0167-4889, 12/2016, Volume 1863, Issue 12, pp. 3096 - 3105
Differentiation of embryonic stem (ES) cells may be regulated by mechanical strain. Herein, signaling molecules underlying mechanical stimulation of... 
Reactive oxygen species | Vasculogenesis | Intracellular calcium | Embryonic stem cells | Mechanical strain | Nitric oxide | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Benzoxazoles - pharmacology | RNA, Small Interfering - genetics | Reactive Oxygen Species - metabolism | Calcium - metabolism | Embryo, Mammalian | Neuropilin-1 - metabolism | Mouse Embryonic Stem Cells - cytology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Mouse Embryonic Stem Cells - drug effects | Reactive Oxygen Species - agonists | Receptors, Immunologic - antagonists & inhibitors | Antigens, CD - metabolism | Embryoid Bodies - metabolism | Embryoid Bodies - cytology | Cell Differentiation | Semaphorins - genetics | Fibroblasts - metabolism | Calcium - agonists | Signal Transduction | Semaphorins - metabolism | Ephrin-B2 - metabolism | Embryoid Bodies - drug effects | Ephrin-B2 - genetics | Biomechanical Phenomena | Myocytes, Cardiac - drug effects | Fibroblast Growth Factor 2 - genetics | Fibroblasts - drug effects | Myocytes, Cardiac - metabolism | Fibroblasts - cytology | Mice | Receptors, Immunologic - genetics | RNA, Small Interfering - metabolism | Receptors, Cell Surface - genetics | Neuropilin-1 - genetics | Neovascularization, Physiologic - drug effects | Mouse Embryonic Stem Cells - metabolism | Neuropilin-1 - antagonists & inhibitors | Receptor, EphB4 - genetics | Ephrin-B2 - antagonists & inhibitors | Egtazic Acid - analogs & derivatives | Fibroblast Growth Factor 2 - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-sis - genetics | Myocytes, Cardiac - cytology | Proto-Oncogene Proteins c-sis - metabolism | Neovascularization, Physiologic - genetics | Gene Expression Regulation | Receptors, Cell Surface - metabolism | Nerve Tissue Proteins - genetics | Receptor, EphB4 - metabolism | Nitric Oxide - agonists | Nerve Tissue Proteins - metabolism | Triazoles - pharmacology | Animals | Egtazic Acid - pharmacology | Nitric Oxide - metabolism | Receptors, Immunologic - metabolism
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 02/2012, Volume 340, Issue 2, pp. 404 - 421
Parkinson's disease (PD) is a debilitating neurodegenerative disorder associated with severe motor impairments caused by the loss of dopaminergic innervation... 
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Catalepsy - drug therapy | Receptors, G-Protein-Coupled - metabolism | Pyrimidines - blood | Humans | Male | Thallium - metabolism | Picolinic Acids - metabolism | Pyrimidines - metabolism | Brain - metabolism | Motor Neuron Disease - drug therapy | Corpus Striatum - pathology | Disease Models, Animal | Triazoles - therapeutic use | Glutamic Acid - pharmacology | Adenosine A2 Receptor Antagonists - therapeutic use | Brain - physiopathology | Rats | Psychomotor Performance - drug effects | Motor Neuron Disease - chemically induced | Rats, Sprague-Dawley | Motor Neuron Disease - pathology | Brain - drug effects | Drug Synergism | Triazoles - metabolism | Calcium Signaling - drug effects | Picolinic Acids - pharmacokinetics | Receptors, G-Protein-Coupled - antagonists & inhibitors | Brain - pathology | Corpus Striatum - drug effects | Tyrosine 3-Monooxygenase - metabolism | Triazoles - blood | Rats, Wistar | Substantia Nigra - pathology | Picolinic Acids - blood | Parkinson Disease - drug therapy | Receptors, Metabotropic Glutamate - metabolism | Receptors, G-Protein-Coupled - agonists | Substantia Nigra - metabolism | Corpus Striatum - metabolism | Dose-Response Relationship, Drug | Adenosine A2 Receptor Antagonists - metabolism | Motor Neuron Disease - metabolism | Oxidopamine - pharmacology | Transfection | Receptors, Metabotropic Glutamate - genetics | Reaction Time - drug effects | HEK293 Cells | Catalepsy - chemically induced | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Drug Therapy, Combination | Motor Neuron Disease - physiopathology | Haloperidol - pharmacology | Picolinic Acids - pharmacology | 3,4-Dihydroxyphenylacetic Acid - metabolism | Corpus Striatum - physiopathology | Levodopa - therapeutic use | Substantia Nigra - drug effects | Animals | Picolinic Acids - therapeutic use | Pyrimidines - therapeutic use | Adenosine A2 Receptor Antagonists - blood | Protein Binding | Receptors, Metabotropic Glutamate - agonists | Levodopa - metabolism | Monoamine Oxidase - metabolism
Journal Article
The journal of clinical endocrinology and metabolism, ISSN 0021-972X, 09/2012, Volume 97, Issue 9, pp. 3333 - 3341
Context: Sitagliptin is an inhibitor of the enzyme dipeptidyl peptidase-IV (DPP-IV), which degrades the incretins, glucagon-like peptide-1 and... 
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Glycated Hemoglobin A - analysis | Tumor Necrosis Factor-alpha - metabolism | Interleukin-6 - analysis | Dipeptidyl Peptidase 4 - metabolism | Prospective Studies | Humans | Middle Aged | Male | Monocytes - metabolism | I-kappa B Kinase - analysis | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | C-Reactive Protein - metabolism | MAP Kinase Kinase 4 - analysis | MAP Kinase Kinase 4 - metabolism | I-kappa B Kinase - metabolism | Glucagon-Like Peptide 1 - analysis | Adult | Female | Sitagliptin Phosphate | C-Reactive Protein - analysis | Interleukin-6 - metabolism | Toll-Like Receptor 4 - analysis | Dipeptidyl Peptidase 4 - analysis | Anti-Inflammatory Agents, Non-Steroidal | Blood Glucose - analysis | Double-Blind Method | Glucagon-Like Peptide 1 - metabolism | Cell Separation | Toll-Like Receptor 2 - metabolism | Receptors, CCR2 - analysis | Toll-Like Receptor 4 - metabolism | Blotting, Western | Tumor Necrosis Factor-alpha - analysis | Monocytes - drug effects | Triazoles - pharmacology | Receptors, CCR2 - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Toll-Like Receptor 2 - analysis | Aged | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Pyrazines - pharmacology | Index Medicus | Abridged Index Medicus | Endocrine Research
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 12/2010, Volume 285, Issue 51, pp. 40104 - 40113
Journal Article
Molecular cell, ISSN 1097-2765, 06/2015, Volume 58, Issue 6, pp. 1028 - 1039
The bromodomain and extraterminal (BET) protein BRD4 is a validated drug target in leukemia, yet its regulatory function in this disease is not well... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Transcriptional Regulator ERG | NIH 3T3 Cells | Oncogene Proteins - genetics | Humans | Leukemia, Myeloid - genetics | Proto-Oncogene Proteins c-myb - genetics | Gene Expression Profiling | Leukemia, Myeloid - pathology | RNA Interference | Proto-Oncogene Protein c-fli-1 - metabolism | Protein Binding - drug effects | Trans-Activators - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins - metabolism | Acute Disease | Proto-Oncogene Protein c-fli-1 - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Oncogene Proteins - metabolism | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | CCAAT-Enhancer-Binding Protein-beta - metabolism | Proto-Oncogene Proteins c-myb - metabolism | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Acetylation - drug effects | Animals | Hematopoietic System - metabolism | Leukemia, Myeloid - metabolism | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Trans-Activators - metabolism | Mice | Histones - metabolism | DNA binding proteins | Medicine, Experimental | Medical research | Chromatin | Lysine | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, pp. e0137210 - e0137210
Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma characterized by the aberrant expression of several growth-regulating, oncogenic effectors.... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cyclin D1 - metabolism | Transcription, Genetic - drug effects | Humans | Gene Expression Regulation, Neoplastic | Proto-Oncogene Proteins c-pim-1 - metabolism | Elongation Factor 2 Kinase - metabolism | Ribosomes - metabolism | Tumor Suppressor Protein p53 - genetics | Elongation Factor 2 Kinase - genetics | Heat Shock Transcription Factors | DNA-Binding Proteins - metabolism | Organelle Biogenesis | Proto-Oncogene Proteins c-bcl-2 - metabolism | Acrylates - pharmacology | Antineoplastic Agents - pharmacology | B-Lymphocytes - pathology | Peptide Elongation Factor 1 - genetics | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Signal Transduction | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | HSP70 Heat-Shock Proteins - genetics | Proto-Oncogene Proteins - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | HSP70 Heat-Shock Proteins - metabolism | Transcription Factors - metabolism | Triazoles - pharmacology | B-Lymphocytes - drug effects | Karyopherins - metabolism | Cyclin D1 - genetics | Active Transport, Cell Nucleus - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Ribosomes - drug effects | Cell Line, Tumor | Karyopherins - genetics | Proto-Oncogene Proteins c-pim-1 - genetics | Protein Biosynthesis - drug effects | Proto-Oncogene Proteins c-myc - genetics | Karyopherins - antagonists & inhibitors | Peptide Elongation Factor 1 - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Genetic aspects | Research | Biological transport | Cell cycle | Ribosomes | Transcription factors | Biomedical research | Transcription | Bcl-2 protein | Laboratories | p53 Protein | Leukemia | c-Myc protein | Multiple myeloma | Immunoblotting | Biosynthesis | Myc protein | Glucose | Cyclin D1 | Cancer therapies | Anticancer properties | Heat shock factors | Proteins | Ribosomal subunits | Cell growth | Translation | Cell survival | Hematology | Hsp70 protein | Gene expression | Lymphoma | Nuclear transport | Molecular chains | Medicine | Molecular modelling | Lymphocytes B | Medical prognosis | Proteomics | Mantle cell lymphoma | Lymphomas | Viability | Heat shock | Apoptosis | Tumors | B-cell lymphoma | Index Medicus
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2011, Volume 51, Issue 6, pp. 906 - 918
.... The effect of DPP-4 inhibitors on myocardial metabolism has not been studied in detail. In wild-type C57Bl6-mice, 3 weeks of treatment with sitagliptin had no effect... 
Cardiovascular | Heart | AMPK | Sitagliptin | Diabetes | Metabolism | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cell Biology | Triazoles - administration & dosage | AMP-Activated Protein Kinases - metabolism | Dipeptidyl Peptidase 4 - metabolism | Glucose Transporter Type 4 - metabolism | Guanine - analogs & derivatives | Pyrazines - administration & dosage | Body Weight - drug effects | Male | Fibrosis - metabolism | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Guanine - metabolism | CD36 Antigens - metabolism | Cell Membrane - metabolism | Phosphorylation - drug effects | Sitagliptin Phosphate | Glucose Tolerance Test | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Myocardium - pathology | Dipeptidyl-Peptidase IV Inhibitors - administration & dosage | Mice, Knockout | Protein Transport | Triazoles - pharmacology | Insulin - metabolism | Myocardium - enzymology | Animals | Glycation End Products, Advanced - metabolism | Heart - drug effects | Mice | Pyrazines - pharmacology | Acetyl-CoA Carboxylase - metabolism | Type 2 diabetes | Analysis | Body weight | Physiological aspects | Glucose | Tumor proteins | Transforming growth factors | Fatty acids | Dextrose | Index Medicus
Journal Article
Redox biology, ISSN 2213-2317, 04/2017, Volume 11, pp. 390 - 402
Uncovering new therapeutic targets for renal fibrosis holds promise for the treatment of chronic kidney diseases. Bromodomain and extra-terminal (BET) protein... 
Nox4 | TGF-β1 | Renal fibrosis | Brd4 | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | RNA, Small Interfering - genetics | Ureteral Obstruction - complications | Reactive Oxygen Species - metabolism | Kidney - pathology | Humans | Male | Ureteral Obstruction - metabolism | Kidney - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | Transforming Growth Factor beta1 - pharmacology | Kidney - drug effects | NADPH Oxidase 4 - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Rats | Epithelial Cells - pathology | Rats, Sprague-Dawley | Reactive Oxygen Species - antagonists & inhibitors | Mitogen-Activated Protein Kinase 3 - metabolism | Fibrosis - etiology | Ureteral Obstruction - pathology | Collagen Type IV - genetics | Cell Cycle Proteins | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Epithelial Cells - metabolism | Transforming Growth Factor beta1 - antagonists & inhibitors | Epithelial Cells - drug effects | Actins - metabolism | Smad3 Protein - metabolism | Actins - genetics | Smad3 Protein - genetics | Fibrosis - prevention & control | Nuclear Proteins - genetics | Collagen Type IV - metabolism | Fibrosis - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Antioxidants - pharmacology | Transcription Factors - genetics | Fibronectins - metabolism | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | NADPH Oxidase 4 - metabolism | Animals | Nuclear Proteins - antagonists & inhibitors | Fibronectins - genetics | Fibrosis - pathology | Ureteral Obstruction - surgery | Cell Line, Transformed | Index Medicus
Journal Article
Biochemistry (Easton), ISSN 0006-2960, 05/2017, Volume 56, Issue 17, pp. 2294 - 2303
The toxicities of azole pollutants that have widespread agricultural and industrial uses are either poorly understood or unknown, particularly with respect to... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Benzimidazoles - toxicity | Triazoles - chemistry | Imidazoles - chemistry | Fungicides, Industrial - toxicity | Isoenzymes - chemistry | Environmental Pollutants - metabolism | Benzimidazoles - chemistry | Recombinant Fusion Proteins - metabolism | Fungicides, Industrial - metabolism | Peroxidases - antagonists & inhibitors | Triazoles - toxicity | Isoenzymes - metabolism | Peroxidases - chemistry | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - toxicity | Peroxidases - metabolism | Imidazoles - toxicity | Environmental Pollutants - toxicity | Pesticides - metabolism | Polychaeta - enzymology | Imidazoles - metabolism | Recombinant Proteins - metabolism | Catalytic Domain | Indazoles - chemistry | Enzyme Inhibitors - metabolism | Computational Biology | Hemoglobins - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Indazoles - metabolism | Recombinant Fusion Proteins - chemistry | Fungicides, Industrial - chemistry | Amino Acid Motifs | Triazoles - metabolism | Hemoglobins - antagonists & inhibitors | Hemoglobins - chemistry | Animals | Environmental Pollutants - chemistry | Hydrogen Bonding | Pesticides - toxicity | Benzimidazoles - metabolism | Indazoles - toxicity | Hydrophobic and Hydrophilic Interactions | Pesticides - chemistry | Ligands | Kinetics | Isoenzymes - antagonists & inhibitors | Azoles (Class of compounds) | Computational chemistry | Usage | Chemical properties | X-ray spectroscopy | Research | Index Medicus
Journal Article