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Chemical Research in Toxicology, ISSN 0893-228X, 09/2008, Volume 21, Issue 9, pp. 1814 - 1822
In vitro covalent binding assessments of drugs have been useful in providing retrospective insights into the association between drug metabolism and a... 
ACYL GLUCURONIDES | CHEMISTRY, MEDICINAL | PROTEIN | RAT | REACTIVE METABOLITES | TIENILIC ACID | HEPATIC-NECROSIS | BIOACTIVATION | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | TOXICOLOGY | HUMAN URINE | Buspirone - chemistry | Raloxifene Hydrochloride - pharmacology | Thiazoles - metabolism | Acetaminophen - metabolism | Humans | Microsomes, Liver - metabolism | Indomethacin - metabolism | Simvastatin - pharmacology | Diclofenac - chemistry | Thiazines - metabolism | Propranolol - pharmacology | Toxicity Tests - methods | Binding Sites | Simvastatin - metabolism | Microsomes, Liver - chemistry | Indomethacin - pharmacology | Paroxetine - metabolism | Raloxifene Hydrochloride - metabolism | Triazoles - metabolism | Ticrynafen - metabolism | Paroxetine - pharmacology | Diclofenac - metabolism | Paroxetine - chemistry | Diphenhydramine - pharmacology | Diclofenac - pharmacology | Triazoles - chemistry | Buspirone - metabolism | Ticrynafen - pharmacology | Structure-Activity Relationship | Buspirone - pharmacology | Hepatocytes - metabolism | Dose-Response Relationship, Drug | Carbamazepine - chemistry | Diphenhydramine - metabolism | Acetaminophen - pharmacology | Microsomes, Liver - drug effects | Propranolol - metabolism | Carbamazepine - metabolism | Thiazines - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Hepatocytes - drug effects | Carbamazepine - pharmacology | Simvastatin - chemistry | Acetaminophen - chemistry | Ticrynafen - chemistry | Propranolol - chemistry | Diphenhydramine - chemistry | Thiazines - chemistry | Triazoles - pharmacology | Indomethacin - chemistry | Thiazoles - chemistry | Thiazoles - pharmacology | Raloxifene Hydrochloride - chemistry | Index Medicus
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 12/2016, Volume 1863, Issue 12, pp. 3096 - 3105
Differentiation of embryonic stem (ES) cells may be regulated by mechanical strain. Herein, signaling molecules underlying mechanical stimulation of... 
Reactive oxygen species | Vasculogenesis | Intracellular calcium | Embryonic stem cells | Mechanical strain | Nitric oxide | PROGENITOR CELLS | CARDIOMYOGENESIS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLOW | CELL BIOLOGY | SEMAPHORIN | SHEAR-STRESS | ENDOTHELIAL-CELLS | GROWTH | BODIES | DIFFERENTIATION | Benzoxazoles - pharmacology | RNA, Small Interfering - genetics | Reactive Oxygen Species - metabolism | Calcium - metabolism | Embryo, Mammalian | Neuropilin-1 - metabolism | Mouse Embryonic Stem Cells - cytology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Mouse Embryonic Stem Cells - drug effects | Reactive Oxygen Species - agonists | Receptors, Immunologic - antagonists & inhibitors | Antigens, CD - metabolism | Embryoid Bodies - metabolism | Embryoid Bodies - cytology | Cell Differentiation | Semaphorins - genetics | Fibroblasts - metabolism | Calcium - agonists | Signal Transduction | Semaphorins - metabolism | Ephrin-B2 - metabolism | Embryoid Bodies - drug effects | Ephrin-B2 - genetics | Biomechanical Phenomena | Myocytes, Cardiac - drug effects | Fibroblast Growth Factor 2 - genetics | Fibroblasts - drug effects | Myocytes, Cardiac - metabolism | Fibroblasts - cytology | Mice | Receptors, Immunologic - genetics | RNA, Small Interfering - metabolism | Receptors, Cell Surface - genetics | Neuropilin-1 - genetics | Neovascularization, Physiologic - drug effects | Mouse Embryonic Stem Cells - metabolism | Neuropilin-1 - antagonists & inhibitors | Receptor, EphB4 - genetics | Ephrin-B2 - antagonists & inhibitors | Egtazic Acid - analogs & derivatives | Fibroblast Growth Factor 2 - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-sis - genetics | Myocytes, Cardiac - cytology | Proto-Oncogene Proteins c-sis - metabolism | Neovascularization, Physiologic - genetics | Gene Expression Regulation | Receptors, Cell Surface - metabolism | Nerve Tissue Proteins - genetics | Receptor, EphB4 - metabolism | Nitric Oxide - agonists | Nerve Tissue Proteins - metabolism | Triazoles - pharmacology | Animals | Egtazic Acid - pharmacology | Nitric Oxide - metabolism | Receptors, Immunologic - metabolism
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 02/2012, Volume 340, Issue 2, pp. 404 - 421
Parkinson's disease (PD) is a debilitating neurodegenerative disorder associated with severe motor impairments caused by the loss of dopaminergic innervation... 
LOCALIZATION | TRANSMISSION | MEDIATED MODULATION | RAT STRIATUM | GLUTAMATE-RECEPTOR-4 | MGLUR4 | BASAL GANGLIA | NEURONS | PHARMACOLOGY & PHARMACY | DYSFUNCTION | AGONISTS | Catalepsy - drug therapy | Receptors, G-Protein-Coupled - metabolism | Pyrimidines - blood | Humans | Male | Thallium - metabolism | Picolinic Acids - metabolism | Pyrimidines - metabolism | Brain - metabolism | Motor Neuron Disease - drug therapy | Corpus Striatum - pathology | Disease Models, Animal | Triazoles - therapeutic use | Glutamic Acid - pharmacology | Adenosine A2 Receptor Antagonists - therapeutic use | Brain - physiopathology | Rats | Psychomotor Performance - drug effects | Motor Neuron Disease - chemically induced | Rats, Sprague-Dawley | Motor Neuron Disease - pathology | Brain - drug effects | Drug Synergism | Triazoles - metabolism | Calcium Signaling - drug effects | Picolinic Acids - pharmacokinetics | Receptors, G-Protein-Coupled - antagonists & inhibitors | Brain - pathology | Corpus Striatum - drug effects | Tyrosine 3-Monooxygenase - metabolism | Triazoles - blood | Rats, Wistar | Substantia Nigra - pathology | Picolinic Acids - blood | Parkinson Disease - drug therapy | Receptors, Metabotropic Glutamate - metabolism | Receptors, G-Protein-Coupled - agonists | Substantia Nigra - metabolism | Corpus Striatum - metabolism | Dose-Response Relationship, Drug | Adenosine A2 Receptor Antagonists - metabolism | Motor Neuron Disease - metabolism | Oxidopamine - pharmacology | Transfection | Receptors, Metabotropic Glutamate - genetics | Reaction Time - drug effects | HEK293 Cells | Catalepsy - chemically induced | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Drug Therapy, Combination | Motor Neuron Disease - physiopathology | Haloperidol - pharmacology | Picolinic Acids - pharmacology | 3,4-Dihydroxyphenylacetic Acid - metabolism | Corpus Striatum - physiopathology | Levodopa - therapeutic use | Substantia Nigra - drug effects | Animals | Picolinic Acids - therapeutic use | Pyrimidines - therapeutic use | Adenosine A2 Receptor Antagonists - blood | Protein Binding | Receptors, Metabotropic Glutamate - agonists | Levodopa - metabolism | Monoamine Oxidase - metabolism | Index Medicus | Neuroscience | Cognitive science | Drug Discovery and Translational Medicine
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 23, pp. 4621 - 4634
The nuclear export protein XPO1 is overexpressed in cancer, leading to the cytoplasmic mislocalization of multiple tumor suppressor proteins. Existing... 
ANTICANCER ACTIVITY | APOPTOSIS | TRANSPORT | PROTEIN | MECHANISM | RITUXIMAB | DRUG-RESISTANCE | CELL-SURVIVAL | CRM1 | HEMATOLOGY | EXPRESSION | Triazoles - chemistry | Humans | Crystallography, X-Ray | Immunoblotting | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Antineoplastic Agents - metabolism | RNA Interference | T-Lymphocytes - metabolism | Acrylates - metabolism | T-Lymphocytes - drug effects | Acrylates - pharmacology | Receptors, Cytoplasmic and Nuclear - chemistry | Interleukin-10 - metabolism | Antineoplastic Agents - pharmacology | Molecular Structure | Interleukin-6 - metabolism | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Acrylates - chemistry | Karyopherins - chemistry | Cells, Cultured | Models, Molecular | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Antineoplastic Agents - chemistry | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Triazoles - pharmacology | Microscopy, Confocal | Triazoles - metabolism | Animals | Karyopherins - metabolism | Active Transport, Cell Nucleus - drug effects | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Cell Line, Tumor | Karyopherins - genetics | Protein Binding | Mice | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 09/2012, Volume 97, Issue 9, pp. 3333 - 3341
Context: Sitagliptin is an inhibitor of the enzyme dipeptidyl peptidase-IV (DPP-IV), which degrades the incretins, glucagon-like peptide-1 and... 
IMMUNITY | DIPEPTIDYL-PEPTIDASE-IV | HEALTHY-SUBJECTS | INSULIN-RESISTANCE | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | RECEPTOR | MICE | CD26 | INHIBITOR SITAGLIPTIN | Glycated Hemoglobin A - analysis | Tumor Necrosis Factor-alpha - metabolism | Interleukin-6 - analysis | Dipeptidyl Peptidase 4 - metabolism | Prospective Studies | Humans | Middle Aged | Male | Monocytes - metabolism | I-kappa B Kinase - analysis | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | C-Reactive Protein - metabolism | MAP Kinase Kinase 4 - analysis | MAP Kinase Kinase 4 - metabolism | I-kappa B Kinase - metabolism | Glucagon-Like Peptide 1 - analysis | Adult | Female | Sitagliptin Phosphate | C-Reactive Protein - analysis | Interleukin-6 - metabolism | Toll-Like Receptor 4 - analysis | Dipeptidyl Peptidase 4 - analysis | Anti-Inflammatory Agents, Non-Steroidal | Blood Glucose - analysis | Double-Blind Method | Glucagon-Like Peptide 1 - metabolism | Cell Separation | Toll-Like Receptor 2 - metabolism | Receptors, CCR2 - analysis | Toll-Like Receptor 4 - metabolism | Blotting, Western | Tumor Necrosis Factor-alpha - analysis | Monocytes - drug effects | Triazoles - pharmacology | Receptors, CCR2 - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Toll-Like Receptor 2 - analysis | Aged | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Pyrazines - pharmacology | Index Medicus | Abridged Index Medicus | Endocrine Research
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2015, Volume 58, Issue 6, pp. 1028 - 1039
The bromodomain and extraterminal (BET) protein BRD4 is a validated drug target in leukemia, yet its regulatory function in this disease is not well... 
SELECTIVE-INHIBITION | RECRUITMENT | C/EBP-ALPHA | CREB-BINDING PROTEIN | CHROMATIN | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | C-MYC | P-TEFB | BRD4 | CELL BIOLOGY | Transcriptional Regulator ERG | NIH 3T3 Cells | Oncogene Proteins - genetics | Humans | Leukemia, Myeloid - genetics | Proto-Oncogene Proteins c-myb - genetics | Gene Expression Profiling | Leukemia, Myeloid - pathology | RNA Interference | Proto-Oncogene Protein c-fli-1 - metabolism | Protein Binding - drug effects | Trans-Activators - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins - metabolism | Acute Disease | Proto-Oncogene Protein c-fli-1 - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Oncogene Proteins - metabolism | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | CCAAT-Enhancer-Binding Protein-beta - metabolism | Proto-Oncogene Proteins c-myb - metabolism | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Acetylation - drug effects | Animals | Hematopoietic System - metabolism | Leukemia, Myeloid - metabolism | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Trans-Activators - metabolism | Mice | Histones - metabolism | DNA binding proteins | Medicine, Experimental | Medical research | Chromatin | Lysine | Index Medicus
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2011, Volume 51, Issue 6, pp. 906 - 918
Abstract Type 2 diabetes is associated with an increased risk of cardiac complications. Inhibitors of dipeptidylpeptidase 4 (DPP-4) are novel drugs for the... 
Cardiovascular | Heart | AMPK | Sitagliptin | Diabetes | Metabolism | CARDIAC & CARDIOVASCULAR SYSTEMS | ACTIVATED PROTEIN-KINASE | DIPEPTIDYL-PEPTIDASE-IV | ACETYL-COA CARBOXYLASE | CELL BIOLOGY | PERFUSED HEARTS | TISSUE DISTRIBUTION | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | PRIOR MYOCARDIAL-INFARCTION | RAT-HEART | DIABETIC DB/DB MICE | Triazoles - administration & dosage | AMP-Activated Protein Kinases - metabolism | Dipeptidyl Peptidase 4 - metabolism | Glucose Transporter Type 4 - metabolism | Guanine - analogs & derivatives | Pyrazines - administration & dosage | Body Weight - drug effects | Male | Fibrosis - metabolism | Dipeptidyl-Peptidase IV Inhibitors - pharmacology | Guanine - metabolism | CD36 Antigens - metabolism | Cell Membrane - metabolism | Phosphorylation - drug effects | Sitagliptin Phosphate | Glucose Tolerance Test | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Myocardium - pathology | Dipeptidyl-Peptidase IV Inhibitors - administration & dosage | Mice, Knockout | Protein Transport | Triazoles - pharmacology | Insulin - metabolism | Myocardium - enzymology | Animals | Glycation End Products, Advanced - metabolism | Heart - drug effects | Mice | Pyrazines - pharmacology | Acetyl-CoA Carboxylase - metabolism | Type 2 diabetes | Analysis | Body weight | Physiological aspects | Glucose | Tumor proteins | Transforming growth factors | Fatty acids | Dextrose | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, pp. e0137210 - e0137210
Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma characterized by the aberrant expression of several growth-regulating, oncogenic effectors.... 
SIGNAL | PROTEIN | CANCER CELLS | MANTLE CELL LYMPHOMA | CYCLIN D1 | MULTIDISCIPLINARY SCIENCES | RESPONSIVE TRANSCRIPTION FACTOR | KINASE | GENE-EXPRESSION | PROLIFERATION | CRM1 | Cyclin D1 - metabolism | Transcription, Genetic - drug effects | Humans | Gene Expression Regulation, Neoplastic | Proto-Oncogene Proteins c-pim-1 - metabolism | Elongation Factor 2 Kinase - metabolism | Ribosomes - metabolism | Tumor Suppressor Protein p53 - genetics | Elongation Factor 2 Kinase - genetics | Heat Shock Transcription Factors | DNA-Binding Proteins - metabolism | Organelle Biogenesis | Proto-Oncogene Proteins c-bcl-2 - metabolism | Acrylates - pharmacology | Antineoplastic Agents - pharmacology | B-Lymphocytes - pathology | Peptide Elongation Factor 1 - genetics | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Signal Transduction | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | HSP70 Heat-Shock Proteins - genetics | Proto-Oncogene Proteins - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | HSP70 Heat-Shock Proteins - metabolism | Transcription Factors - metabolism | Triazoles - pharmacology | B-Lymphocytes - drug effects | Karyopherins - metabolism | Cyclin D1 - genetics | Active Transport, Cell Nucleus - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Ribosomes - drug effects | Cell Line, Tumor | Karyopherins - genetics | Proto-Oncogene Proteins c-pim-1 - genetics | Protein Biosynthesis - drug effects | Proto-Oncogene Proteins c-myc - genetics | Karyopherins - antagonists & inhibitors | Peptide Elongation Factor 1 - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Genetic aspects | Research | Biological transport | Cell cycle | Ribosomes | Transcription factors | Biomedical research | Transcription | Bcl-2 protein | Laboratories | p53 Protein | Leukemia | c-Myc protein | Multiple myeloma | Immunoblotting | Biosynthesis | Myc protein | Glucose | Cyclin D1 | Cancer therapies | Anticancer properties | Heat shock factors | Proteins | Ribosomal subunits | Cell growth | Translation | Cell survival | Hematology | Hsp70 protein | Gene expression | Lymphoma | Nuclear transport | Molecular chains | Medicine | Molecular modelling | Lymphocytes B | Medical prognosis | Proteomics | Mantle cell lymphoma | Lymphomas | Viability | Heat shock | Apoptosis | Tumors | B-cell lymphoma | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2016, Volume 22, Issue 9, pp. 1002 - 1012
Altered metabolism has been implicated in the pathogenesis of inflammatory diseases. NADPH oxidase 4 (NOX4), a source of cellular superoxide anions, has... 
MEDICINE, RESEARCH & EXPERIMENTAL | CARNITINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PALMITOYLTRANSFERASE-I | CELL BIOLOGY | DIABETES-MELLITUS | NAD(P)H OXIDASE | METABOLISM | INSULIN-RESISTANCE | DISEASE | NOX4 | BETA-CELL | STRESS | Benzoxazoles - pharmacology | Metabolomics | Carnitine O-Palmitoyltransferase - genetics | Humans | Immunoblotting | Lipid Metabolism - immunology | DNA-Binding Proteins - metabolism | Calcium-Binding Proteins - immunology | Carnitine O-Palmitoyltransferase - metabolism | Adaptor Proteins, Signal Transducing - immunology | NADPH Oxidases - genetics | Fatty Acids - metabolism | Real-Time Polymerase Chain Reaction | Macrophages - immunology | Cytokines - immunology | Pyrazoles - pharmacology | Calcium-Binding Proteins - metabolism | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Oxidation-Reduction | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | NADPH Oxidases - antagonists & inhibitors | NADPH Oxidase 4 | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Streptococcus pneumoniae | Triazoles - pharmacology | Macrophages - metabolism | Animals | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Inflammasomes - immunology | Lipid Metabolism - drug effects | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Pyridines - pharmacology | Streptococcal Infections - immunology | Adaptor Proteins, Signal Transducing - metabolism | Oxidases | Transferases | Cellular signal transduction | Genetic aspects | Properties | Enzyme activation | Health aspects | Oxidation | Metabolism | Fatty acids | Cells | Index Medicus
Journal Article
STEM CELLS, ISSN 1066-5099, 08/2011, Volume 29, Issue 8, pp. 1186 - 1195
Gamete failure‐derived infertility affects millions of people worldwide; for many patients, gamete donation by unrelated donors is the only available... 
Human induced pluripotent stem cells | Haploid cells | Meiosis | Germ cells | In vitro differentiation | DERIVATION | HUMAN TESTIS | MOUSE | PRIMORDIAL GERM-CELLS | CULTURE | CELL & TISSUE ENGINEERING | CELL BIOLOGY | SEMINIFEROUS EPITHELIUM | IN-VITRO | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENERATION | DIFFERENTIATION | FETAL | HEMATOLOGY | Nestin | Vimentin - metabolism | Humans | Fibroblast Growth Factor 2 - pharmacology | Male | Spermatogonia - metabolism | Antigens, CD - metabolism | DNA Methylation | Stage-Specific Embryonic Antigens - metabolism | Karyotyping | 3-Hydroxysteroid Dehydrogenases - metabolism | Cell Culture Techniques | Spermatogonia - cytology | DEAD-box RNA Helicases - metabolism | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Cell Line | Promoter Regions, Genetic | Gene Expression | Induced Pluripotent Stem Cells - physiology | Benzothiazoles - pharmacology | Colforsin - pharmacology | Gene Expression Regulation | Nuclear Proteins - metabolism | Leukemia Inhibitory Factor - pharmacology | Nerve Tissue Proteins - metabolism | Proteins - genetics | Triazoles - pharmacology | DEAD-box RNA Helicases - genetics | Adaptor Proteins, Signal Transducing | Proteins - metabolism | Cell Differentiation - drug effects | Ploidies | Histones - metabolism | Intermediate Filament Proteins - metabolism | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 01/2008, Volume 451, Issue 7176, pp. 330 - 334
Inflammatory diseases and neuropathic insults are frequently accompanied by severe and debilitating pain, which can become chronic and often unresponsive to... 
Inflammation - chemically induced | Analgesics - pharmacology | Spinal Cord - drug effects | Spinal Cord - metabolism | Diazepam - metabolism | Rats, Wistar | Capsaicin - pharmacology | Analgesics - metabolism | Male | Ganglia, Spinal - cytology | Pain - chemically induced | Receptors, GABA-A - chemistry | Pain - metabolism | Brain - physiology | Formaldehyde | Protein Subunits - metabolism | Diazepam - pharmacology | Fluorobenzenes - pharmacology | Protein Isoforms - metabolism | Inflammation - drug therapy | Pain - drug therapy | Protein Isoforms - chemistry | Neurons - metabolism | Spinal Cord - cytology | Neurons - drug effects | Chronic Disease - drug therapy | Disease Models, Animal | Analgesics - therapeutic use | Fluorobenzenes - metabolism | Pain - prevention & control | Diazepam - administration & dosage | Analgesics - administration & dosage | Rats | Hot Temperature | Organ Specificity | Brain - drug effects | Triazoles - pharmacology | Triazoles - metabolism | Animals | Receptors, GABA-A - genetics | Mice | Protein Subunits - chemistry | Receptors, GABA-A - metabolism | Spinal Cord - physiopathology | Ganglia, Spinal - metabolism | Care and treatment | Receptors | Analgesics | GABA | Development and progression | Dosage and administration | Research | Health aspects | Chronic pain | Neurosciences | Neurotransmitters | NMR | Rodents | Pain management | Pharmacology | Nuclear magnetic resonance | Binding sites | Inflammatory diseases | Index Medicus
Journal Article