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double-blind method (7) 7
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1. Full Text Angiotensin II Type 1 Receptor Blockers Reduce Urinary Oxidative Stress Markers in Hypertensive Diabetic Nephropathy
by Ogawa, Susumu and Mori, Takefumi and Nako, Kazuhiro and Kato, Taro and Takeuchi, Kazuhisa and Ito, Sadayoshi
Hypertension, ISSN 0194-911X, 04/2006, Volume 47, Issue 4, pp. 699 - 705
We tested the hypothesis that blockade of angiotensin II type 1 receptors reduces oxidative stress markers in parallel with urinary albumin and type IV... 
Oxidative stress | Inflammation | Albuminuria | Angiotensin II | LOSARTAN | MELLITUS | BLOOD-PRESSURE | TRIAL | albuminuria | inflammation | angiotensin II | MICROALBUMINURIA | IN-VIVO | PERIPHERAL VASCULAR DISEASE | COMPLICATIONS | CANDESARTAN | BLOCKADE | oxidative stress | Diabetic Nephropathies - urine | Single-Blind Method | Biomarkers - urine | Valsartan | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Middle Aged | Valine - analogs & derivatives | Diabetic Nephropathies - drug therapy | Hypertension - drug therapy | Male | Antihypertensive Agents - therapeutic use | Albuminuria - physiopathology | Trichlormethiazide - therapeutic use | Adult | Female | Tetrazoles - therapeutic use | Valine - therapeutic use | Aged | Oxidative Stress - drug effects | Hypertension - urine | Benzimidazoles - therapeutic use
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2. Full Text Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients
by Hosaka, Miki and Inoue, Ryusuke and Satoh, Michihiro and Watabe, Daisuke and Hanazawa, Tomohiro and Ohkubo, Takayoshi and Asayama, Kei and Obara, Taku and Imai, Yutaka and J-HOME-ALB Study Grp and J-HOME-ALB Study group
Clinical and Experimental Hypertension, ISSN 1064-1963, 07/2018, Volume 40, Issue 5, pp. 468 - 475
The aim of this study was to assess the effects of irbesartan alone and combined with amlodipine, efonidipine, or trichlormethiazide on blood pressure (BP) and... 
Home blood pressure | irbesartan | microalbuminuria | efonidipine | trichlormethiazide | amlodipine | ACE-INHIBITOR | NONDIABETIC INDIVIDUALS | LOW-GRADE ALBUMINURIA | CALCIUM-CHANNEL BLOCKERS | GENERAL-POPULATION | RENAL PROTECTION | CARDIOVASCULAR MORTALITY | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | PERIPHERAL VASCULAR DISEASE | CHRONIC KIDNEY-DISEASE | CORONARY-HEART-DISEASE | Albuminuria - complications | Antihypertensive Agents - pharmacology | Tetrazoles - pharmacology | Urinalysis | Humans | Middle Aged | Essential Hypertension - complications | Male | Biphenyl Compounds - therapeutic use | Essential Hypertension - drug therapy | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Trichlormethiazide - therapeutic use | Nitrophenols - therapeutic use | Organophosphorus Compounds - pharmacology | Female | Blood Pressure - drug effects | Trichlormethiazide - pharmacology | Albuminuria - urine | Drug Therapy, Combination | Organophosphorus Compounds - therapeutic use | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Dihydropyridines - therapeutic use | Irbesartan | Albuminuria - drug therapy | Amlodipine - pharmacology | Dihydropyridines - pharmacology | Tetrazoles - therapeutic use | Aged | Blood Pressure Monitoring, Ambulatory
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3. Full Text Angiotensin-II receptor antagonist combined with calcium channel blocker or diuretic for essential hypertension
by Ishimitsu, Toshihiko and Numabe, Atsushi and Masuda, Toshihide and Akabane, Tomoyuki and Okamura, Atsushi and Minami, Junichi and Matsuoka, Hiroaki
Hypertension Research, ISSN 0916-9636, 11/2009, Volume 32, Issue 11, pp. 962 - 968
To achieve the target blood pressure recommended by the latest guidelines, multiple antihypertensive drugs are needed in most patients. In this study, the... 
C-REACTIVE PROTEIN | angiotensin II receptor antagonist | thiazide diuretic | PULSE-WAVE VELOCITY | AZELNIDIPINE | COMBINATION THERAPY | LOW-DENSITY-LIPOPROTEIN | CHRONIC KIDNEY | BLOOD-PRESSURE | calcium channel blocker | ARTERIAL STIFFNESS | ANKLE VASCULAR INDEX | PERIPHERAL VASCULAR DISEASE | HEART-RATE | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Ankle Brachial Index | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Male | Sodium Chloride Symporter Inhibitors - therapeutic use | Azetidinecarboxylic Acid - analogs & derivatives | Azetidinecarboxylic Acid - therapeutic use | C-Reactive Protein - metabolism | Trichlormethiazide - therapeutic use | Adult | Female | Blood Pressure - drug effects | Imidazoles - therapeutic use | Albuminuria - urine | Drug Therapy, Combination | Glomerular Filtration Rate | Hypertension - physiopathology | Cross-Over Studies | Dihydropyridines - therapeutic use | Albuminuria - drug therapy | Diuretics - therapeutic use | Tetrazoles - therapeutic use | Aged | Lipoproteins, LDL - blood
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4. Full Text Effects of eplerenone on blood pressure and glucose metabolism in Japanese hypertensives with overweight or obesity
by Adachi, H and Kakuma, T and Kawaguchi, M and Kumagai, E and Fukumoto, Y and KES Study Investigators
MEDICINE, ISSN 0025-7974, 04/2019, Volume 98, Issue 15, p. e14994
Objective: The impact of aldosterone blockade using eplerenone on hypertensives with obesity has not been clarified. We compared the efficacy and safety... 
MORTALITY | CHRONIC HEART-FAILURE | MANAGEMENT | EFFICACY | SAFETY | eplerenone | FOLLOW-UP | trichlormethiazide | MINERALOCORTICOID RECEPTOR BLOCKADE | MEDICINE, GENERAL & INTERNAL | INSULIN-RESISTANCE | DOUBLE-BLIND | ALDOSTERONE | glucose metabolism | hypertension | obesity | Hypoglycemic Agents - therapeutic use | Overweight - complications | Overweight - drug therapy | Eplerenone - therapeutic use | Humans | Middle Aged | Hypertension - drug therapy | Male | Treatment Outcome | Overweight - physiopathology | Antihypertensive Agents - therapeutic use | Hypertension - physiopathology | Trichlormethiazide - therapeutic use | Glucose - metabolism | Hypertension - complications | Female | Aged | Blood Pressure - drug effects | Hypertension | Overweight persons | Glucose metabolism | Drug therapy | Health aspects | Patient outcomes
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5. Full Text Olmesartan with azelnidipine versus with trichlormethiazide on home blood pressure variability in patients with type II diabetes mellitus
by Ushigome, Emi, MD, PhD and Matsumoto, Shinobu, MD, PhD and Oyabu, Chikako, PhD and Ushigome, Hidetaka, MD, PhD and Yokota, Isao, MPH, PhD and Hasegawa, Goji, MD, PhD and Nakamura, Naoto, MD, PhD and Tanaka, Muhei, MD, PhD and Yamazaki, Masahiro, MD, PhD and Fukui, Michiaki, MD, PhD
Journal of the American Society of Hypertension, ISSN 1933-1711, 2016, Volume 11, Issue 3, pp. 140 - 147
Abstract The aim of the present study was to compare the effects of olmesartan combined with azelnidipine versus olmesartan combined with trichlormethiazide,... 
Cardiovascular | telemedicine system | open-label cross-over pilot study | home blood pressure variability | Antihypertensive medication | SELF-MEASUREMENT | MONOTHERAPY | VALIDATION | CALCIUM-CHANNEL BLOCKERS | EUROPEAN-SOCIETY | AMLODIPINE | RECEPTOR BLOCKER | PERIPHERAL VASCULAR DISEASE | ESSENTIAL-HYPERTENSION | PROTOCOL REVISION 2010 | CARDIOVASCULAR RISK | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Male | Antihypertensive Agents - therapeutic use | Azetidinecarboxylic Acid - analogs & derivatives | Cross-Over Studies | Dihydropyridines - therapeutic use | Drug Therapy, Combination - methods | Pilot Projects | Azetidinecarboxylic Acid - therapeutic use | Trichlormethiazide - therapeutic use | Hypertension - prevention & control | Diuretics - therapeutic use | Female | Tetrazoles - therapeutic use | Aged | Blood Pressure - drug effects | Blood Pressure Monitoring, Ambulatory - methods | Imidazoles - therapeutic use | Diabetes Mellitus, Type 2 - complications
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6. Full Text Effects of an Angiotensin II Receptor Blocker on the Impaired Function of Endothelial Progenitor Cells in Patients With Essential Hypertension
by Suzuki, Ryo and Fukuda, Noboru and Katakawa, Mayumi and Tsunemi, Akiko and Tahira, Yoshiko and Matsumoto, Taro and Ueno, Takahiro and Soma, Masayoshi
American Journal of Hypertension, ISSN 0895-7061, 5/2014, Volume 27, Issue 5, pp. 695 - 701
BACKGROUND Endothelial progenitor cells (EPCs) induce neovascularization and repair vascular damage. We have demonstrated that EPC function is impaired in... 
blood pressure | angiotensin II receptor blocker | essential hypertension | colony formation | endothelial progenitor cell | human | hypertension | CONVERTING ENZYME | OXIDATIVE STRESS | VIVO | RATS | IN-VITRO | PERIPHERAL VASCULAR DISEASE | ANTAGONISTS | EXPRESSION | CULTURES | CARDIOVASCULAR RISK | LIFE | Prospective Studies | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Middle Aged | Hypertension - drug therapy | Male | Stem Cells - metabolism | Time Factors | Trichlormethiazide - therapeutic use | Female | Blood Pressure - drug effects | Hypertension - diagnosis | Endothelial Cells - metabolism | Japan | Cells, Cultured | Treatment Outcome | Antihypertensive Agents - therapeutic use | Hypertension - pathology | Hypertension - physiopathology | Hypertension - metabolism | Cross-Over Studies | Losartan - therapeutic use | Stem Cells - drug effects | Stem Cells - pathology | Diuretics - therapeutic use | Cell Proliferation - drug effects | Oxidative Stress - drug effects | Endothelial Cells - pathology | Endothelial Cells - drug effects | Essential hypertension | Somatic cells | Patient outcomes | Angiotensin II receptor blockers | Dosage and administration | Drug therapy | Health aspects | Endothelium | Hypertension | Colonies & territories | Oxidative stress | Rodents
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7. Full Text Comparison of azelnidipine and trichlormethiazide in Japanese type 2 diabetic patients with hypertension:The COAT randomized controlled trial
by Takihata, Masahiro and Nakamura, Akinobu and Kondo, Yoshinobu and Kawasaki, Satsuki and Kimura, Mari and Terauchi, Yasuo
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0125519
Objective This study compared the efficacy and safety of azelnidipine with that of trichlormethiazide in Japanese type 2 diabetic patients with hypertension.... 
AMLODIPINE | COMBINATION | IRBESARTAN | MULTIDISCIPLINARY SCIENCES | Calcium Channel Blockers - adverse effects | Dihydropyridines - administration & dosage | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Male | Azetidinecarboxylic Acid - adverse effects | Azetidinecarboxylic Acid - analogs & derivatives | Dihydropyridines - adverse effects | Trichlormethiazide - adverse effects | Azetidinecarboxylic Acid - therapeutic use | Trichlormethiazide - therapeutic use | Female | Blood Pressure - drug effects | Diabetes Mellitus, Type 2 - complications | Diuretics - administration & dosage | Trichlormethiazide - administration & dosage | Japan | Risk Factors | Treatment Outcome | Dihydropyridines - therapeutic use | Calcium Channel Blockers - administration & dosage | Hypertension - complications | Diuretics - therapeutic use | Aged | Diabetes Mellitus, Type 2 - drug therapy | Diuretics - adverse effects | Azetidinecarboxylic Acid - administration & dosage | Hypertension | Type 2 diabetes | Trichlormethiazide | Dosage and administration | Research | Diagnosis | Drug therapy | Comparative analysis | Diabetic retinopathy | Edema | Diabetes mellitus | Clinical trials | Glucose | Metabolism | Patients | Insulin | Blood | Medicine | Hospitals | Older people | Diuretics | Blood pressure | Hypoglycemic agents | Diabetes | Health risk assessment | Drug dosages | Endocrinology
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8. Full Text Diuretics Prevent Thiazolidinedione-Induced Cardiac Hypertrophy without Compromising Insulin-Sensitizing Effects in Mice
by Chang, Cherng-Shyang and Tsai, Pei-Jane and Sung, Junne-Ming and Chen, Ju-Yi and Ho, Li-Chun and Pandya, Kumar and Maeda, Nobuyo and Tsai, Yau-Sheng
American Journal of Pathology, The, ISSN 0002-9440, 2014, Volume 184, Issue 2, pp. 442 - 453
Much concern has arisen regarding critical adverse effects of thiazolidinediones (TZDs), including rosiglitazone and pioglitazone, on cardiac tissue. Although... 
Pathology | PLACEBO-CONTROLLED CROSSOVER | CARDIOMYOCYTE | ACTIVATED-RECEPTOR-GAMMA | DOUBLE-BLIND | PPAR-GAMMA | DEATH | ROSIGLITAZONE | PATHOLOGY | CONGESTIVE-HEART-FAILURE | INDUCED FLUID RETENTION | WATER | Extracellular Signal-Regulated MAP Kinases - metabolism | PPAR gamma - metabolism | Furosemide - therapeutic use | Spironolactone - pharmacology | Trichlormethiazide - therapeutic use | Ultrasonography | Lipid Metabolism - genetics | Trichlormethiazide - pharmacology | Spironolactone - therapeutic use | Insulin - pharmacology | Diuretics - pharmacology | Mice, Inbred C57BL | Cardiomegaly - diagnostic imaging | Cardiomegaly - drug therapy | Signal Transduction - genetics | Thiazolidinediones - adverse effects | Cardiac Volume - drug effects | Gene Expression Regulation - drug effects | Animals | Cardiomegaly - prevention & control | Signal Transduction - drug effects | Lipid Metabolism - drug effects | Cardiomegaly - chemically induced | Glucose - metabolism | Diuretics - therapeutic use | Mice | Furosemide - pharmacology | Regular
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9. Full Text Effects of an ARB on Endothelial Progenitor Cell Function and Cardiovascular Oxidation in Hypertension
by Yu, Yi and Fukuda, Noboru and Yao, En-Hui and Matsumoto, Taro and Kobayashi, Naohiko and Suzuki, Ryo and Tahira, Yoshiko and Ueno, Takahiro and Matsumoto, Koichi
American Journal of Hypertension, ISSN 0895-7061, 01/2008, Volume 21, Issue 1, pp. 72 - 77
Background Angiotensin II (Ang II) receptor blocker (ARB) has been reported to have protective effects on the cardiovascular system independent of blood... 
MYOCARDIAL-INFARCTION | OXIDASE | RENIN-ANGIOTENSIN SYSTEM | DISEASE | GENE-EXPRESSION | RATS | STEM-CELL | PERIPHERAL VASCULAR DISEASE | NEOVASCULARIZATION | STRESS | NEOINTIMA | Antihypertensive Agents - pharmacology | Tetrazoles - pharmacology | Angiotensin II Type 1 Receptor Blockers - therapeutic use | NADPH Oxidases - metabolism | Hypertension - drug therapy | Male | Vascular Endothelial Growth Factor A - metabolism | Aorta - metabolism | Spin Labels | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Angiotensin II Type 1 Receptor Blockers - pharmacology | Cyclic N-Oxides - pharmacology | Myocardium - metabolism | NADPH Oxidases - genetics | Trichlormethiazide - pharmacology | Benzimidazoles - therapeutic use | Disease Models, Animal | Endothelial Cells - metabolism | Rats | Antihypertensive Agents - therapeutic use | Hypertension - metabolism | Cell Movement - drug effects | Chemokine CXCL12 - metabolism | Benzimidazoles - pharmacology | Oxidative Stress - drug effects | Endothelial Cells - enzymology | Sodium Chloride, Dietary - administration & dosage | Rats, Inbred WKY | Proto-Oncogene Proteins c-kit - metabolism | Stem Cells - metabolism | Chemokine CXCL12 - genetics | Stem Cells - enzymology | Proto-Oncogene Proteins c-kit - genetics | Blood Pressure - drug effects | Aorta - enzymology | Rats, Inbred SHR | Diuretics - pharmacology | Aorta - drug effects | Cells, Cultured | Renin-Angiotensin System - genetics | Thiobarbituric Acid Reactive Substances - metabolism | Antioxidants - pharmacology | Hypertension - physiopathology | Antioxidants - therapeutic use | Myocardium - enzymology | Animals | Stem Cells - drug effects | Renin-Angiotensin System - drug effects | Tetrazoles - therapeutic use | Cell Proliferation - drug effects | Endothelial Cells - drug effects | Hypertension | Physiological aspects | Oxidation-reduction reaction | Angiotensin II receptor blockers | Endothelium
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10. Full Text A case of nephrogenic diabetes insipidus during transsphenoidal pituitary adenomectomy
by Miyoshi, Hirotsugu and Nakamura, Ryuji and Hamada, Hiroshi
Journal of Neurosurgical Anesthesiology, ISSN 0898-4921, 01/2016, Volume 28, Issue 1, pp. 79 - 80
SURGERY | ANESTHESIOLOGY | CLINICAL NEUROLOGY | Pituitary Neoplasms - surgery | Diabetes Insipidus, Nephrogenic - drug therapy | Diabetes Insipidus, Nephrogenic - complications | Trichlormethiazide - therapeutic use | Vasopressins - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Pituitary Gland - surgery | Humans | Female | Aged | Sodium Chloride Symporter Inhibitors - therapeutic use | Intraoperative Complications - drug therapy
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11. Full Text Randomized double-blind comparison of a calcium antagonist and a diuretic in elderly hypertensives: National intervention cooperative study in elderly hypertensives study group
by Kuramoto, Kizuku
Hypertension, ISSN 0194-911X, 1999, Volume 34, Issue 5, pp. 1129 - 1133
Although diuretics are recommended for the treatment of hypertension, decreased diuretic use and increased calcium antagonist use necessitate a comparison of... 
Hypertension | Diuretics | Elderly | Calcium antagonist | Double-Blind Method | Humans | Calcium Channel Blockers - therapeutic use | Pulse | Hypertension - drug therapy | Male | Nicardipine - therapeutic use | Sodium Chloride Symporter Inhibitors - therapeutic use | Hypertension - physiopathology | Trichlormethiazide - adverse effects | Nicardipine - adverse effects | Trichlormethiazide - therapeutic use | Hypertension - complications | Female | Aged | Blood Pressure - drug effects
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12. Full Text Combination Therapy of Calcium Channel Blocker and Angiotensin II Receptor Blocker Reduces Augmentation Index in Hypertensive Patients
by Doi, Masayuki and Miyoshi, Toru and Hirohata, Satoshi and Kamikawa, Shigeshi and Ogawa, Hiroko and Ninomiya, Yoshifumi and Kusachi, Shozo and Usui, Shinichi and Kaji, Youko and Sakane, Kosuke
The American Journal of the Medical Sciences, ISSN 0002-9629, 05/2010, Volume 339, Issue 5, pp. 433 - 439
The optimal combination treatment for hypertension has not been established. We investigated the effect of a calcium channel blocker or a diuretic added to... 
Hypertension | Angiotensin receptor blocker | Combination therapy | Calcium channel blocker | Wave reflection | Calcium channelblocker | CONVERTING ENZYME-INHIBITOR | OXIDATIVE STRESS | ASYMMETRIC DIMETHYLARGININE | WAVE-FORM | ANTIHYPERTENSIVE DRUG | CENTRAL AORTIC PRESSURE | BLOOD-PRESSURE | ACE-INHIBITORS | MEDICINE, GENERAL & INTERNAL | ARTERIAL STIFFNESS | NITRIC-OXIDE | Diuretics - administration & dosage | Trichlormethiazide - administration & dosage | Dihydropyridines - administration & dosage | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Male | Azetidinecarboxylic Acid - analogs & derivatives | Hypertension - physiopathology | Dihydropyridines - therapeutic use | Azetidinecarboxylic Acid - therapeutic use | Trichlormethiazide - therapeutic use | Calcium Channel Blockers - administration & dosage | Diuretics - therapeutic use | Female | Aged | Blood Pressure - drug effects | Drug Therapy, Combination | Angiotensin II Type 1 Receptor Blockers - administration & dosage | Azetidinecarboxylic Acid - administration & dosage
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13. Full Text Duloxetine-induced hyponatremia in an elderly patient treated with thiazide diuretics
by Mori, Miyu and Koide, Tetsuro and Imanishi, Yoshinori and Matsui, Yuriyo and Matsuda, Toru
Indian Journal of Pharmacology, ISSN 0253-7613, 11/2014, Volume 46, Issue 6, pp. 657 - 659
Hyponatremia is a known adverse effect of duloxetine, and it can lead to potentially life-threatening complications. Administration of thiazide diuretics also... 
duloxetine | Drug interaction | syndrome of inappropriate secretion of antidiuretic hormone syndrome | trichlormethiazide | PHARMACOLOGY & PHARMACY | Hyponatremia - chemically induced | Drug Interactions | Thiophenes - adverse effects | Trichlormethiazide - therapeutic use | Humans | Aged, 80 and over | Duloxetine Hydrochloride | Female | Antidepressive Agents - adverse effects | Sodium Chloride Symporter Inhibitors - therapeutic use | Causes of | Diuretics | Aged patients | Dosage and administration | Hyponatremia | Drug therapy | Drug Watch
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14. Full Text CUL3 gene analysis enables early intervention for pediatric pseudohypoaldosteronism type II in infancy
by Osawa, Madori and Ogura, Yumi and Isobe, Kiyoshi and Uchida, Shinichi and Nonoyama, Shigeaki and Kawaguchi, Hiroyuki
Pediatric Nephrology, ISSN 0931-041X, 9/2013, Volume 28, Issue 9, pp. 1881 - 1884
Four genes responsible for pseudohypoaldosteronism type II (PHA-II) have been identified, thereby facilitating molecular diagnostic testing.A 1-year-old boy... 
Hypertension | Pediatrics | Sodium-chloride co-transporter | Hyperkalemia | Medicine & Public Health | Pseudohypoaldosteronism | Cullin-3 | Metabolic acidosis | ACIDOSIS | UROLOGY & NEPHROLOGY | PEDIATRICS | MUTATIONS | Acid-Base Imbalance - blood | Pseudohypoaldosteronism - therapy | Genetic Testing | Introns - genetics | Acidosis - etiology | Pseudohypoaldosteronism - genetics | Humans | RNA, Messenger - genetics | Exons - genetics | Infant | Male | Acidosis - therapy | Acid-Base Imbalance - genetics | Cullin Proteins - genetics | Trichlormethiazide - therapeutic use | Pseudohypoaldosteronism - diagnosis | Diuretics - therapeutic use | Potassium - blood | Bicarbonates - blood | Blood Pressure - physiology | Chlorides - blood | Real-Time Polymerase Chain Reaction | Case studies | Medical research | Medicine, Experimental | Hypoaldosteronism | Children | Diseases | Acidosis
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15. Full Text Salt-losing nephrogenic diabetes insipidus caused by fetal exposure to angiotensin receptor blocker
by Miura, Kenichiro and Sekine, Takashi and Iida, Atsuko and Takahashi, Kazuhiro and Igarashi, Takashi
Pediatric Nephrology, ISSN 0931-041X, 2009, Volume 24, Issue 6, pp. 1235 - 1238
The administration of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin type 1 receptor blockers (ARBs) to pregnant women has been reported to... 
Water restriction test | Urine cyclic AMP | Angiotensin receptor blocker fetopathy | Nephrotoxicity | Urinary concentrating ability | Vasopressin V2 receptor | RATS | UROLOGY & NEPHROLOGY | PEDIATRICS | MECHANISMS | ENZYME-INHIBITOR FETOPATHY | ENALAPRIL | Prenatal Exposure Delayed Effects | Angiotensin II Type 1 Receptor Blockers - adverse effects | Diabetes Insipidus, Nephrogenic - physiopathology | Humans | Child, Preschool | Male | Treatment Outcome | Aspartic Acid - therapeutic use | Sodium Chloride Symporter Inhibitors - therapeutic use | Kidney Function Tests | Pregnancy | Glomerular Filtration Rate - drug effects | Renal Insufficiency - therapy | Arginine Vasopressin - metabolism | Trichlormethiazide - therapeutic use | Female | Peritoneal Dialysis - methods | Child | Cyclic AMP - urine | Diabetes Insipidus, Nephrogenic - chemically induced | Causes of | Antihypertensive drugs | Complications and side effects | Usage | Diabetes insipidus | Index Medicus
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16. Full Text Comparison of Effects of Low Dose of Spironolactone and a Thiazide Diuretic in Patients with Hypertension Treated with an Angiotensin-Converting Enzyme Inhibitor or an Angiotensin Type 1 Receptor Blocker
by Yutaka, Miyashita and Mifune, Mizuo and Kubota, Eiji and Itoh, Hiroshi and Saito, Ikuo
Clinical and Experimental Hypertension, ISSN 1064-1963, 12/2009, Volume 31, Issue 8, pp. 648 - 656
This study was performed to investigate the additional anti-hypertensive effects and safety of low-dose thiazide diuretic, trichlormethiazide (TCTZ), and a... 
spironolactone | hypertension | thiazide diuretics | Hypertension | Spironolactone | Thiazide diuretics | PHARMACOLOGY & PHARMACY | PERIPHERAL VASCULAR DISEASE | ALDOSTERONE | BLOOD-PRESSURE | Diuretics - administration & dosage | Trichlormethiazide - administration & dosage | Prospective Studies | Spironolactone - administration & dosage | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Middle Aged | Hypertension - drug therapy | Treatment Outcome | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Hypertension - physiopathology | Dose-Response Relationship, Drug | Outpatients | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Trichlormethiazide - therapeutic use | Diuretics - therapeutic use | Aged | Blood Pressure - drug effects | Drug Therapy, Combination | Spironolactone - therapeutic use | Angiotensin II Type 1 Receptor Blockers - administration & dosage
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17. Full Text Combining irbesartan and trichlormethiazide enhances blood pressure reduction via inhibition of sympathetic activity without adverse effects on metabolism in hypertensive rats with metabolic syndrome
by Nishihara, Masaaki and Hirooka, Yoshitaka and Sunagawa, Kenji
Clinical and Experimental Hypertension, ISSN 1064-1963, 2/2015, Volume 37, Issue 1, pp. 33 - 38
Abstract Sympathoexcitation and oxidative stress in the brain have pivotal roles in hypertension with metabolic syndrome (MetS). Here, we examined whether oral... 
metabolic syndrome | combination therapy | sympathetic activity | Angiotensin II receptor blocker | diuretics | hypertension | Hypertension | Diuretics | Sympathetic activity | Combination therapy | Metabolic syndrome | SYMPATHOEXCITATION | OXIDATIVE STRESS | RECEPTOR BLOCKADE | NERVE ACTIVITY | TELMISARTAN | OBESITY | CARDIOVASCULAR REGULATION |