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by Peloso, Gina M and Auer, Paul L and Bis, Joshua C and Voorman, Arend and Morrison, Alanna C and Stitziel, Nathan O and Brody, Jennifer A and Khetarpal, Sumeet A and Crosby, Jacy R and Fornage, Myriam and Isaacs, Aaron and Jakobsdottir, Johanna and Feitosa, Mary F and Davies, Gail and Huffman, Jennifer E and Manichaikul, Ani and Davis, Brian and Lohman, Kurt and Joon, Aron Y and Smith, Albert V and Grove, Megan L and Zanoni, Paolo and Redon, Valeska and Demissie, Serkalem and Lawson, Kim and Peters, Ulrike and Carlson, Christopher and Jackson, Rebecca D and Ryckman, Kelli K and Mackey, Rachel H and Robinson, Jennifer G and Siscovick, David S and Schreiner, Pamela J and Mychaleckyj, Josyf C and Pankow, James S and Hofman, Albert and Uitterlinden, Andre G and Harris, Tamara B and Taylor, Herman A and Taylor, Kent D and Stafford, Jeanette M and Reynolds, Lindsay M and Marioni, Riccardo E and Dehghan, Abbas and Franco, Oscar H and Patel, Aniruddh P and Lu, Yingchang and Hindy, George and Gottesman, Omri and Bottinger, Erwin P and Melander, Olle and Orho-Melander, Marju and Loos, Ruth J.F and Duga, Stefano and Merlini, Piera Angelica and Farrall, Martin and Goel, Anuj and Asselta, Rosanna and Girelli, Domenico and Martinelli, Nicola and Shah, Svati H and Kraus, William E and Li, Mingyao and Rader, Daniel J and Reilly, Muredach P and McPherson, Ruth and Watkins, Hugh and Ardissino, Diego and Zhang, Qunyuan and Wang, Judy and Tsai, Michael Y and Correa, Adolfo and Griswold, Michael E and Lange, Leslie A and Starr, John M and Rudan, Igor and Eiriksdottir, Gudny and Launer, Lenore J and Ordovas, Jose M and Levy, Daniel and Chen, Y.-D. Ida and Reiner, Alexander P and Hayward, Caroline and Polasek, Ozren and Deary, Ian J and Borecki, Ingrid B and Liu, Yongmei and Gudnason, Vilmundur and Wilson, James G and van Duijn, Cornelia M and Kooperberg, Charles and Rich, Stephen S and Psaty, Bruce M and Rotter, Jerome I and O’Donnell, Christopher J and Rice, Kenneth and Boerwinkle, Eric and Kathiresan, Sekar and Cupples, L. Adrienne and NHLBI GO Exome Sequencing Project and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and EpiHealth: Epidemiology for Health and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
The American Journal of Human Genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 223 - 232
Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin type 9 gene ( ) lower plasma low-density lipoprotein cholesterol... 
DENSITY-LIPOPROTEIN CHOLESTEROL | FACTOR ACETYLHYDROLASES | PROTEIN | LDL | GENETICS & HEREDITY | PCSK9 | PLATELET-ACTIVATING-FACTOR | TRAITS | Genetic Code | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Male | Genetic Variation | 1-Alkyl-2-acetylglycerophosphocholine Esterase - genetics | Adult | Cholesterol, LDL - blood | Female | Subtilisins - metabolism | African Continental Ancestry Group - genetics | Coronary Disease - blood | European Continental Ancestry Group - genetics | Genetic Association Studies | Gene Frequency | Mice, Inbred C57BL | Linear Models | Cholesterol, HDL - genetics | Sequence Analysis, DNA | 1-Alkyl-2-acetylglycerophosphocholine Esterase - metabolism | Cholesterol, LDL - genetics | Phenotype | Animals | Coronary Disease - genetics | Alleles | Triglycerides - blood | Cholesterol, HDL - blood | Subtilisins - genetics | Aged | Mice | Cohort Studies | Genetic code | Genetic variation | Physiological aspects | Genetic research | Genetic aspects | Research | Coronary heart disease | Population genetics | Lipids | Cardiovascular disease | Low density lipoprotein | Risk assessment | Deoxyribonucleic acid--DNA | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Kilpeläinen, Tuomas O and Bentley, Amy R and Noordam, Raymond and Sung, Yun Ju and Schwander, Karen and Winkler, Thomas W and Jakupović, Hermina and Chasman, Daniel I and Manning, Alisa and Ntalla, Ioanna and Aschard, Hugues and Brown, Michael R and de las Fuentes, Lisa and Franceschini, Nora and Guo, Xiuqing and Vojinovic, Dina and Aslibekyan, Stella and Feitosa, Mary F and Kho, Minjung and Musani, Solomon K and Richard, Melissa and Wang, Heming and Wang, Zhe and Bartz, Traci M and Bielak, Lawrence F and Campbell, Archie and Dorajoo, Rajkumar and Fisher, Virginia and Hartwig, Fernando P and Horimoto, Andrea R. V. R and Li, Changwei and Lohman, Kurt K and Marten, Jonathan and Sim, Xueling and Smith, Albert V and Tajuddin, Salman M and Alver, Maris and Amini, Marzyeh and Boissel, Mathilde and Chai, Jin Fang and Chen, Xu and Divers, Jasmin and Evangelou, Evangelos and Gao, Chuan and Graff, Mariaelisa and Harris, Sarah E and He, Meian and Hsu, Fang-Chi and Jackson, Anne U and Zhao, Jing Hua and Kraja, Aldi T and Kühnel, Brigitte and Laguzzi, Federica and Lyytikäinen, Leo-Pekka and Nolte, Ilja M and Rauramaa, Rainer and Riaz, Muhammad and Robino, Antonietta and Rueedi, Rico and Stringham, Heather M and Takeuchi, Fumihiko and van der Most, Peter J and Varga, Tibor V and Verweij, Niek and Ware, Erin B and Wen, Wanqing and Li, Xiaoyin and Yanek, Lisa R and Amin, Najaf and Arnett, Donna K and Boerwinkle, Eric and Brumat, Marco and Cade, Brian and Canouil, Mickaël and Chen, Yii-Der Ida and Concas, Maria Pina and Connell, John and de Mutsert, Renée and de Silva, H. Janaka and de Vries, Paul S and Demirkan, Ayşe and Ding, Jingzhong and Eaton, Charles B and Faul, Jessica D and Friedlander, Yechiel and Gabriel, Kelley P and Ghanbari, Mohsen and Giulianini, Franco and Gu, Chi Charles and Gu, Dongfeng and Harris, Tamara B and He, Jiang and Heikkinen, Sami and Heng, Chew-Kiat and Hunt, Steven C and Ikram, M. Arfan and Jonas, Jost B and Koh, Woon-Puay and Komulainen, Pirjo and Krieger, Jose E and ... and Lifelines Cohort Study
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 376 - 11
Journal Article
Nature, ISSN 0028-0836, 04/2017, Volume 544, Issue 7649, pp. 235 - 239
Journal Article
by Zhao, Wei and Rasheed, Asif and Tikkanen, Emmi and Lee, Jung-Jin and Butterworth, Adam S and Howson, Joanna M. M and Assimes, Themistocles L and Chowdhury, Rajiv and Orho-Melander, Marju and Damrauer, Scott and Small, Aeron and Asma, Senay and Imamura, Minako and Yamauch, Toshimasa and Chambers, John C and Chen, Peng and Sapkota, Bishwa R and Shah, Nabi and Jabeen, Sehrish and Surendran, Praveen and Lu, Yingchang and Zhang, Weihua and Imran, Atif and Abbas, Shahid and Majeed, Faisal and Trindade, Kevin and Qamar, Nadeem and Mallick, Nadeem Hayyat and Yaqoob, Zia and Saghir, Tahir and Hasan Rizvi, Syed Nadeem and Memon, Anis and Rasheed, Syed Zahed and Memon, Fazal-Ur-Rehman and Mehmood, Khalid and Ahmed, Naveeduddin and Hussain Qureshi, Irshad and Tanveer-Us-Salam, Tanveer-Us-Salam and Iqbal, Wasim and Malik, Uzma and Mehra, Narinder and Kuo, Jane Z and Sheu, Wayne H.-H and Guo, Xiuqing and Hsiung, Chao A and Juang, Jyh-Ming J and Taylor, Kent D and Hung, Yi-Jen and Lee, Wen-Jane and Quertermous, Thomas and Lee, I-Te and Hsu, Chih-Cheng and Bottinger, Erwin P and Ralhan, Sarju and Teo, Yik Ying and Wang, Tzung-Dau and Alam, Dewan S and Di Angelantonio, Emanuele and Epstein, Steve and Nielsen, Sune F and Nordestgaard, Borge G and Tybjaerg-Hansen, Anne and Young, Robin and Benn, Marianne and Frikke-Schmidt, Ruth and Kamstrup, Pia R and Jukema, J. Wouter and Sattar, Naveed and Smit, Roelof and Chung, Ren-Hua and Liang, Kae-Woei and Anand, Sonia and Sanghera, Dharambir K and Ripatti, Samuli and Loos, Ruth J. F and Kooner, Jaspal S and Tai, E. Shyong and Rotter, Jerome I and Ida Chen, Yii-Der and Frossard, Philippe and Maeda, Shiro and Kadowaki, Takashi and Reilly, Muredach and Pare, Guillaume and Melander, Olle and Salomaa, Veikko and Rader, Daniel J and Danesh, John and Voight, Benjamin F and Saleheen, Danish and EPIC-CVD Consortium and CHD Exome Consortium and EPIC-Interact Consortium and Michigan Biobank and CHD Exome+ Consortium and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and EpiHealth: Epidemiology for Health and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Nature Genetics, ISSN 1061-4036, 10/2017, Volume 49, Issue 10, pp. 1450 - 1457
To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic... 
METAANALYSIS | AP2 | VARIANTS | ACID-BINDING PROTEIN | GENETICS & HEREDITY | ATHEROSCLEROSIS | RISK | GENETIC ARCHITECTURE | MENDELIAN RANDOMIZATION | GENOME-WIDE ASSOCIATION | ARTERY-DISEASE | Diabetes Mellitus, Type 2 - genetics | Humans | Asian Continental Ancestry Group - genetics | Genetic Loci - genetics | Coronary Disease - epidemiology | Mutation, Missense | Molecular Targeted Therapy | Diabetes Mellitus, Type 2 - epidemiology | Diabetes Mellitus, Type 2 - etiology | HLA-DRB5 Chains - genetics | Metabolic Syndrome - epidemiology | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Comorbidity | Risk Factors | Coronary Disease - etiology | Europe - epidemiology | Asia - epidemiology | Metabolic Networks and Pathways - genetics | Coronary Disease - genetics | Metabolic Syndrome - genetics | Biomarkers | Polymorphism, Single Nucleotide | Diabetes Mellitus, Type 2 - drug therapy | Quantitative trait loci | Type 2 diabetes | Genetic variation | Genetic aspects | Health aspects | Coronary heart disease | Risk factors | Drugs | Diabetes mellitus | Cardiovascular disease | Triglycerides | Genomes | Genetic diversity | Adipocytes | Risk analysis | Fatty acids | Loci | Coronary artery disease | Meta-analysis | Proteins | Pathways | Etiology | Atherosclerosis | Gene loci | Histocompatibility antigen HLA | Diabetes | Cardiovascular diseases | Bioinformatics | Heart diseases | Index Medicus | Medical and Health Sciences | single nucleotide polymorphism | major clinical study | ischemic heart disease | Genetic Loci | HLA DRB5 gene | genetic risk | genetic predisposition | East Asian | Diabetes Mellitus, Type 2 | genetic susceptibility | metabolic syndrome X | Basic Medicine | gene | Europe | Caucasian | genetic variation | European Continental Ancestry Group | South Asian | European | non insulin dependent diabetes mellitus | Metabolic Networks and Pathways | HLA-DRB5 Chains | metabolism | molecularly targeted therapy | comparative study | HLA DRB5 antigen | CCDC92 gene | Medicin och hälsovetenskap | Article | fatty acid binding protein 4 | missense mutation | Medicinsk genetik | Medical Genetics | genetics | Coronary Disease | icosapentaenoic acid ethyl ester | priority journal | human | risk factor | genetic variability | gene locus | comorbidity | biological marker | controlled study | Asian continental ancestry group | Asia | genome-wide association study | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Walter, Klaudia and Min, Josine L and Huang, Jie and Crooks, Lucy and Memari, Yasin and McCarthy, Shane and Perry, John and Xu, Changjiang and Futema, Marta and Lawson, Daniel and Iotchkova, Valentina and Schiffels, Stephan and Henicks, Auey E and Danecek, Petr and Li, Rui and Floyd, James and Wain, Louise and Barroso, Inês and Humphries, Steve and Hurles, Matthew and Zeggini, Eleftheria and Barrett, Jeffrey C and Plagnol, Vincent and Richards, Brent and Greenwood, Celia and Timpson, Nicholas and Durbin, Richard and Bala, Senduran and Clapham, Peter and Coates, Guy and Cox, Tony and Daly, Allan and Du, Yuanping and Edkins, Ted and Ellis, Peter and Flicek, Paul and Guo, Xiaosen and Guo, Xueqin and Huang, Liren and Jackson, David K and Joyce, Chris and Keane, Thomas and Kolb-Kokocinski, Anja and Langford, Cordelia and Li, Yingrui and Liang, Jieqin and Lin, Hong and Liu, Ryan and Maslen, John and Muddyman, Dawn and Quail, Michael A and Stalker, Jim and Sun, Jianping and Tian, Jing and Wang, Guangbiao and Wang, Jun and Wang, Yu and Wong, Kim and Zhang, Pingbo and Birney, Ewan and Boustred, Chris and Chen, Lu and Clement, Gail and Cocca, Massimiliano and Smith, G.D and Day, Ian N.M and Day-Williams, Aaron and Down, Thomas and Dunham, David and Evans, David M and Gaunt, Tom and Geihs, Matthias and Hart, Deborah and Howie, Bryan and Hubbard, Tim and Hysi, Pirro and Jamshidi, Yalda and Karczewski, Konrad and Kemp, John and Lachance, Genevieve and Lek, Monkol and Lopes, Margarida and MacArthur, Daniel G and Marchini, Jonathan and Mangino, Massimo and Mathieson, Iain and Metrustry, Sarah and Moayyeri, Alireza and Northstone, Kate and Panoutsopoulou, Kalliope and Paternoster, Lavinia and Quaye, Lydia and Ring, Susan and Ritchie, Graham R.S and Shihab, Hashem A and Shin, So-Youn and Small, Kerrin and Artigas, M.S and Soranzo, Nicole and Southam, Lorraine and ... and UCLEB Consortium and UK10K Consortium and The UK10K Consortium
Nature: international weekly journal of science, ISSN 0028-0836, 10/2015, Volume 526, Issue 7571, pp. 82 - 89
Journal Article
PLoS Genetics, ISSN 1553-7390, 06/2011, Volume 7, Issue 6, pp. e1002138 - e1002138
Journal Article
PLoS Genetics, ISSN 1553-7390, 10/2017, Volume 13, Issue 10, pp. e1007079 - e1007079