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Nature Immunology, ISSN 1529-2908, 08/2010, Volume 11, Issue 8, pp. 717 - 724
Journal Article
Immunity, ISSN 1074-7613, 12/2017, Volume 47, Issue 6, pp. 1083 - 1099.e6
The immunosuppressive protein PD-L1 is upregulated in many cancers and contributes to evasion of the host immune system. The relative importance of the tumor... 
PD-L1 | TTP | KRAS | RAS | tristetraprolin | immunotherapy | CELL LUNG-CANCER | ACTIVATED PROTEIN-KINASE | EPITHELIAL-CELLS | TRISTETRAPROLIN | MELANOMA-CELLS | TNF-ALPHA | IMMUNOLOGY | EXPRESSION | CHECKPOINT BLOCKADE | Proto-Oncogene Proteins p21(ras) - immunology | Neoplasm Transplantation | RNA, Messenger - immunology | Tumor Escape | Proto-Oncogene Proteins p21(ras) - genetics | Tristetraprolin - immunology | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Intracellular Signaling Peptides and Proteins - immunology | Lung Neoplasms - pathology | Male | Female | Intracellular Signaling Peptides and Proteins - genetics | Lung Neoplasms - genetics | Signal Transduction | MAP Kinase Kinase Kinases - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Protein-Serine-Threonine Kinases - genetics | Epithelial Cells - pathology | RNA Cleavage | RNA Stability | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | MAP Kinase Kinase Kinases - immunology | Lung Neoplasms - immunology | Animals | Colorectal Neoplasms - immunology | Tristetraprolin - genetics | Epithelial Cells - immunology | Cell Line, Tumor | Protein Binding | Protein-Serine-Threonine Kinases - immunology | Mice | Mice, Inbred BALB C | Colorectal Neoplasms - pathology | Messenger RNA | Gastrointestinal diseases | Immunotherapy | Colorectal cancer | Cellular signal transduction | Cancer | Protein binding | Transcription factors | Cytokines | Lung cancer | Genomes | Ras protein | Kinases | Ribonucleic acid--RNA | Patients | Proteins | Signal transduction | Immunosuppression | 3' Untranslated regions | DNA methylation | Tumor necrosis factor-TNF | Ligands | Protein expression | Mutation | Oncogenes | Tumors
Journal Article
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2011, Volume 7, Issue 1, pp. 560 - n/a
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2002, Volume 277, Issue 11, pp. 9606 - 9613
Tristetraprolin (TTP), the prototype of a small family of CCCH tandem zinc finger (TZF) domain proteins, is a physiological stimulator of instability of the... 
tristetraprolin
Journal Article
Science, ISSN 0036-8075, 04/2016, Volume 352, Issue 6284, pp. 453 - 459
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2013, Volume 19, Issue 5, pp. 1169 - 1179
Purpose: Invasion is the critical step in progression of a precancerous lesion to squamous cell carcinoma of the head and neck (HNSCC). Invasion is regulated... 
SURVIVAL | PROTEIN TRISTETRAPROLIN | THERAPY | TUMOR PROGRESSION | ONCOLOGY | IN-VIVO | FACTOR MESSENGER-RNA | PROLIFERATION | GROWTH-FACTOR | BINDING PROTEIN | INTERLEUKIN-6 | RNA, Small Interfering - genetics | Cell Proliferation | Immunoprecipitation | Luciferases - metabolism | Tissue Array Analysis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | 3' Untranslated Regions - genetics | Head and Neck Neoplasms - metabolism | Matrix Metalloproteinase 9 - genetics | Tristetraprolin - metabolism | Matrix Metalloproteinase 9 - secretion | p38 Mitogen-Activated Protein Kinases - metabolism | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | rap1 GTP-Binding Proteins - metabolism | Interleukin-6 - genetics | Neoplasm Invasiveness | RNA, Messenger - genetics | Tristetraprolin - antagonists & inhibitors | p38 Mitogen-Activated Protein Kinases - genetics | Chorioallantoic Membrane - metabolism | RNA Stability | Reverse Transcriptase Polymerase Chain Reaction | Chick Embryo | Interleukin-6 - secretion | Blotting, Western | Head and Neck Neoplasms - pathology | Matrix Metalloproteinase 2 - genetics | Animals | Tristetraprolin - genetics | Head and Neck Neoplasms - genetics | Matrix Metalloproteinase 2 - secretion | Neoplasm Staging | rap1 GTP-Binding Proteins - genetics | Apoptosis | Cell Movement | chick chorioallantoic membrane assay (CAM) | oral cancer equivalent (OCE) | cytokines | post-transcriptional regulation | 3′UTR
Journal Article