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Journal of Neuroscience, ISSN 0270-6474, 03/2012, Volume 32, Issue 12, pp. 4240 - 4246
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 02/2006, Volume 96, Issue 3, pp. 656 - 668
Glial subcellular re‐sealed particles (referred to as gliosomes here) were purified from rat cerebral cortex and investigated for their ability to release... 
exocytosis | gliosomes | glutamate release | SNARE proteins | Glutamate release | Exocytosis | Gliosomes | NEURONAL-ACTIVITY | SYNAPTIC VESICLES | HIPPOCAMPAL ASTROCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLASMALEMMAL VESICLES | SYNAPTOSOMES | CALCIUM WAVES | NEUROSCIENCES | AMINO-ACIDS | CULTURED ASTROCYTES | H+-ATPASE | IN-SITU | Disks Large Homolog 4 Protein | L-Lactate Dehydrogenase - metabolism | Propionates - metabolism | Neuroglia - ultrastructure | Microscopy, Electron, Transmission - methods | Microtubule-Associated Proteins - metabolism | Vesicular Transport Proteins - metabolism | Male | Intracellular Signaling Peptides and Proteins - metabolism | Synaptosomes - metabolism | Glial Fibrillary Acidic Protein - metabolism | Cerebral Cortex - cytology | Exocytosis - physiology | Dose-Response Relationship, Drug | Tubulin - metabolism | Tritium - metabolism | Time Factors | Macrolides - pharmacology | Membrane Proteins - metabolism | Ionophores - pharmacology | Calcium - pharmacology | Myelin Basic Protein - metabolism | Vesicular Glutamate Transport Protein 1 - metabolism | Fluorescent Antibody Technique - methods | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | S100 Proteins - metabolism | D-Aspartic Acid - metabolism | Microscopy, Confocal - methods | Rats, Sprague-Dawley | Synaptosomes - ultrastructure | Animals | Ionomycin - pharmacology | Neuroglia - metabolism | Glutamic Acid - metabolism | Synaptosomal-Associated Protein 25 - metabolism | CD11b Antigen - metabolism | Vesicle-Associated Membrane Protein 2 - metabolism | Proteins | Brain | Amino acids | Neurotransmitters | Neurons | Rodents
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 01/2010, Volume 298, Issue 1, pp. 59 - 67
The recently discovered peptide apelin is known to be involved in the maintenance of insulin sensitivity. However, questions persist regarding its precise role... 
Obesity | Insulin resistance | Diabetes | Hormones | 3T3-L1 ADIPOCYTES | METABOLIC SYNDROME | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | hormones | HEART-FAILURE | ACETYL-COA CARBOXYLASE | APJ RECEPTOR | MIDDLE-AGED MEN | IN-VIVO | ENDOTHELIAL-CELLS | ENDOCRINOLOGY & METABOLISM | STIMULATES GLUCOSE-UPTAKE | insulin resistance | diabetes | obesity | Phosphorylation - physiology | AMP-Activated Protein Kinases - metabolism | Deoxyglucose - metabolism | Receptors, Leptin - genetics | Muscle, Skeletal - metabolism | Tritium | Diabetes Mellitus, Type 2 - metabolism | Myoblasts - metabolism | Insulin Resistance - physiology | Myoblasts - cytology | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Apelin | Hyperinsulinism - physiopathology | Hyperinsulinism - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Dietary Sucrose - pharmacology | Intercellular Signaling Peptides and Proteins | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Obesity - physiopathology | Adipokines | Mice, Knockout | Obesity - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Signal Transduction - drug effects | Signal Transduction - physiology | Mice | Receptors, Leptin - metabolism | AMP-Activated Protein Kinases - genetics | Prevention | Glucose metabolism | Physiological aspects | Research | Peptide hormones | Risk factors
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2012, Volume 32, Issue 32, pp. 10841 - 10853
Delineation of key molecules that act epigenetically to transduce diverse stressors into established patterns of disease would facilitate the advent of... 
OXIDATIVE STRESS | HEME OXYGENASE-1 EXPRESSION | PREPULSE INHIBITION | ALZHEIMERS-DISEASE | SPINAL CORD BARRIER | ALPHA-SYNUCLEIN EXPRESSION | IMMUNE ACTIVATION | INCREASE LOCOMOTOR-ACTIVITY | OVER-EXPRESSION | CEREBROSPINAL-FLUID | NEUROSCIENCES | Glial Fibrillary Acidic Protein - genetics | Heme Oxygenase-1 - metabolism | Protein Binding - genetics | Superoxide Dismutase - genetics | Embryo, Mammalian | Homeodomain Proteins - metabolism | Humans | MicroRNAs - metabolism | Gait Disorders, Neurologic - genetics | Schizophrenia - pathology | Nuclear Receptor Subfamily 4, Group A, Member 2 - genetics | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - metabolism | Receptors, Dopamine D1 - metabolism | Schizophrenia - genetics | Dopamine Agents - pharmacokinetics | Protein Binding - drug effects | alpha-Synuclein - genetics | Disease Models, Animal | Inhibition (Psychology) | Animals, Newborn | Mice, Transgenic | Laser-Doppler Flowmetry | Astrocytes - ultrastructure | Tyrosine 3-Monooxygenase - genetics | Analysis of Variance | Brain - pathology | Mice | MicroRNAs - genetics | Biogenic Monoamines - metabolism | Gait Disorders, Neurologic - etiology | Tritium - pharmacokinetics | Astrocytes - metabolism | Tyrosine 3-Monooxygenase - metabolism | Age Factors | Benzamides - pharmacokinetics | Gene Expression Regulation, Developmental - genetics | Chromatography, High Pressure Liquid | Receptors, Dopamine D2 - metabolism | Heme Oxygenase-1 - genetics | Schizophrenia - physiopathology | Sensory Gating - genetics | Superoxide Dismutase - metabolism | Enzyme-Linked Immunosorbent Assay | Acoustic Stimulation | Transcription Factors - genetics | Benzazepines - pharmacokinetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Animals | Nuclear Receptor Subfamily 4, Group A, Member 2 - metabolism | alpha-Synuclein - metabolism
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 05/2016, Volume 89, Issue 5, pp. 593 - 605
Here we describe the pharmacologic properties of a series of clinically relevant chemoattractant receptor-homologous molecules expressed on T-helper type 2... 
BINDING-KINETICS | RECEPTOR-HOMOLOGOUS MOLECULE | PHARMACOLOGICAL CHARACTERIZATION | ANTIGEN CHALLENGE | TH2 LYMPHOCYTES | MAST-CELLS | T(H)2 CELLS | PHARMACOLOGY & PHARMACY | PLASMA-PROTEIN | ALLERGIC DISEASES | PROSTAGLANDIN D-2 | Prostaglandin D2 - antagonists & inhibitors | Eosinophils - drug effects | Pyridines - chemistry | Humans | Acetates - chemistry | Th2 Cells - immunology | Anti-Allergic Agents - pharmacology | Eosinophils - immunology | Indoleacetic Acids - chemistry | Th2 Cells - drug effects | Receptors, Immunologic - antagonists & inhibitors | Receptors, Immunologic - agonists | Solubility | Recombinant Proteins - chemistry | Anti-Allergic Agents - metabolism | Ligands | Kinetics | Receptors, Immunologic - genetics | Eosinophils - metabolism | Drugs, Investigational - pharmacology | Cricetulus | Tritium | Drugs, Investigational - metabolism | Receptors, Prostaglandin - metabolism | Drugs, Investigational - chemistry | Indoles - metabolism | Receptors, Prostaglandin - genetics | Prostaglandin D2 - metabolism | Anti-Allergic Agents - chemistry | Indoles - pharmacology | Receptors, Prostaglandin - antagonists & inhibitors | CHO Cells | Binding, Competitive | Recombinant Proteins - metabolism | Indoleacetic Acids - metabolism | Acetates - metabolism | Cells, Cultured | Th2 Cells - cytology | Th2 Cells - metabolism | Cell Shape - drug effects | Animals | Pyridines - metabolism | Receptors, Prostaglandin - agonists | Indoleacetic Acids - pharmacology | Acetates - pharmacology | Pyridines - pharmacology | Eosinophils - cytology | Indoles - chemistry | Receptors, Immunologic - metabolism
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 10/2015, Volume 49, Issue 2, pp. 287 - 300
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 06/2001, Volume 88, Issue 12, pp. 1276 - 1282
Itis generally accepted that endothelial cells generate most of their ATP byanaerobic glycolysis and that very little ATP is derived from the oxidation offatty... 
AICAR | Fuel metabolism | Acetyl CoA carboxylase | Glucose transport | Malonyl CoA | glucose transport | malonyl CoA | CARDIAC & CARDIOVASCULAR SYSTEMS | fuel metabolism | NITRIC-OXIDE SYNTHASE | OLEIC-ACID | ACETYL-COA CARBOXYLASE | VASCULAR ENDOTHELIUM | SKELETAL-MUSCLE | acetyl CoA carboxylase | METABOLISM | MALONYL-COA | GLUCOSE | PERIPHERAL VASCULAR DISEASE | NO SYNTHASE | HEMATOLOGY | CEREBRAL MICROVESSELS | Endothelium, Vascular - cytology | Palmitic Acid - metabolism | Humans | Multienzyme Complexes - metabolism | Endothelium, Vascular - drug effects | Tritium | Carnitine - metabolism | Caprylates - metabolism | Glycolysis - drug effects | AMP-Activated Protein Kinases | Aminoimidazole Carboxamide - pharmacology | Dose-Response Relationship, Drug | Ribonucleotides - pharmacology | Malonyl Coenzyme A - metabolism | Carnitine - pharmacology | Adenosine Triphosphate - metabolism | Oxidation-Reduction - drug effects | Aminoimidazole Carboxamide - metabolism | Energy Metabolism - physiology | Fatty Acids - metabolism | 3-O-Methylglucose - pharmacokinetics | Intracellular Fluid - metabolism | Protein-Serine-Threonine Kinases - metabolism | Ribonucleotides - metabolism | Cells, Cultured | Umbilical Veins | Glucose - pharmacology | Enzyme Activation - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Endothelium, Vascular - metabolism | Glucose - pharmacokinetics | Glucose - metabolism | Acetyl-CoA Carboxylase - metabolism | Energy Metabolism - drug effects
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 1/2013, Volume 33, Issue 1, pp. 53 - 58
Journal Article
Glia, ISSN 0894-1491, 05/2012, Volume 60, Issue 6, pp. 894 - 907
Journal Article
Neuroscience, ISSN 0306-4522, 2012, Volume 225, pp. 65 - 75
Highlights ► Morphologically activated microglia seen up to 28 days after diffuse brain injury. ► Inflammatory genes acutely elevated in thalamus & cortex... 
Neurology | anti-inflammatory | alternate activation | classical activation | neuroplasticity | Neuroplasticity | Anti-inflammatory | Classical activation | Alternate activation | NEUTROPHIL INFILTRATION | MACROPHAGES | NEURONAL INJURY | AXON REGENERATION | SPINAL-CORD | MYELOID CELLS | NEUROSCIENCES | CLOSED-HEAD INJURY | LATE-ONSET | EXPRESSION | ALTERNATIVE ACTIVATION | Ibuprofen - therapeutic use | Microglia - metabolism | Isoquinolines - pharmacokinetics | Ventral Thalamic Nuclei - pathology | Male | Brain Injuries - physiopathology | Somatosensory Cortex - pathology | Histocompatibility Antigens Class I - metabolism | Encephalitis - drug therapy | Time Factors | Protein Binding - drug effects | Microglia - pathology | Histocompatibility Antigens Class II - metabolism | Microfilament Proteins - metabolism | Radioligand Assay | Cytokines - genetics | Disease Models, Animal | Calcium-Binding Proteins - metabolism | Cytokines - metabolism | Somatosensory Cortex - drug effects | Gene Expression Regulation - physiology | Rats | Histocompatibility Antigens Class I - genetics | Ventral Thalamic Nuclei - drug effects | Rats, Sprague-Dawley | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Analysis of Variance | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Receptors, GABA-A - genetics | Cyclooxygenase 2 - metabolism | Gene Expression Regulation - radiation effects | Receptors, GABA-A - metabolism | Histocompatibility Antigens Class II - genetics | Brain Injuries - pathology | Somatosensory Cortex - metabolism | Tritium - pharmacokinetics | Encephalitis - etiology | Ventral Thalamic Nuclei - metabolism | Brain | Neurosciences | Genes | Ibuprofen | Genetic research | Universities and colleges | Injuries | Protein binding
Journal Article
13.