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Human Reproduction, ISSN 0268-1161, 04/2016, Volume 31, Issue 4, pp. 700 - 711
Abstract STUDY QUESTION Are the immune regulatory molecules programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) involved in regulating... 
CD4+T | miscarriage | Th2 bias | pregnancy | trophoblast | PD-1 | Tim-3 | ALLOGRAFT-REJECTION | IMMUNITY | PROTECTION | THYMIC STROMAL LYMPHOPOIETIN | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | COSTIMULATORY PATHWAYS | CD4(+)T | DIFFERENTIATION | PDL1 | EXHAUSTION | FETOMATERNAL TOLERANCE | Abortion, Habitual - pathology | Fetal Resorption - prevention & control | Coculture Techniques | Humans | Hepatitis A Virus Cellular Receptor 2 - metabolism | Abortion, Habitual - immunology | Fetal Resorption - metabolism | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Th2 Cells - immunology | CD4-Positive T-Lymphocytes - pathology | Abortion, Habitual - metabolism | Pregnancy Trimester, First | Programmed Cell Death 1 Receptor - blood | Th2 Cells - drug effects | Abortion, Induced | CD4-Positive T-Lymphocytes - immunology | Hepatitis A Virus Cellular Receptor 2 - antagonists & inhibitors | Abortion, Habitual - blood | Antibodies, Neutralizing - therapeutic use | Female | Fetal Resorption - pathology | Maternal-Fetal Exchange - drug effects | Th2 Cells - pathology | Immune Tolerance - drug effects | Decidua - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Hepatitis A Virus Cellular Receptor 2 - blood | Programmed Cell Death 1 Receptor - metabolism | Antibodies, Neutralizing - pharmacology | Decidua - pathology | Fetal Resorption - immunology | Th2 Cells - metabolism | Decidua - metabolism | Pregnancy | Tocolytic Agents - pharmacology | Tocolytic Agents - therapeutic use | Animals | Cell Proliferation - drug effects | Mice | Decidua - drug effects | CD4-Positive T-Lymphocytes - drug effects | Crosses, Genetic
Journal Article
STEM CELLS, ISSN 1066-5099, 02/2008, Volume 26, Issue 2, pp. 300 - 311
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56289
An essential aspect of stem cell culture is the successful maintenance of the undifferentiated state. Many types of stem cells are FGF2 dependent, and... 
TROPHOBLAST | DERIVATION | HUMAN ES | MULTIDISCIPLINARY SCIENCES | GROWTH | SELF-RENEWAL | PLGA MICROSPHERES | VASCULAR NICHE | DIFFERENTIATION | FATE | LINES | Embryonic Stem Cells - cytology | Humans | Fibroblast Growth Factor 2 - pharmacology | Stem Cells - cytology | Neural Stem Cells - cytology | Cell Culture Techniques - methods | Cells, Immobilized - drug effects | Microspheres | Stem Cells - enzymology | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - enzymology | Induced Pluripotent Stem Cells - drug effects | Lactic Acid | Polyglycolic Acid | Cells, Cultured | Neural Stem Cells - drug effects | Embryonic Stem Cells - enzymology | Enzyme Activation - drug effects | Cells, Immobilized - cytology | Neural Stem Cells - enzymology | Animals | MAP Kinase Signaling System - drug effects | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Culture Media - pharmacology | Stem Cells - drug effects | Mice | Mitogen-Activated Protein Kinases - metabolism | Embryonic stem cells | Fibroblast growth factors | Fibroblast growth factor 2 | Bioengineering | Cell culture | Biotechnology | Media (culture) | Stability | Embryo cells | Cultures | Embryos | Feeding | Polylactide-co-glycolide | Biomedical materials | Stem cells | Differentiation | Growth factors | Pluripotency | Controlled release | Public health
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 502, Issue 7471, pp. 340 - 345
Reprogramming of adult cells to generate induced pluripotent stem cells (iPS cells) has opened new therapeutic opportunities; however, little is known about... 
TRANSCRIPTION FACTORS | GENE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MOUSE | DIRECT CONVERSION | NEURONS | GENERATION | DIFFERENTIATION | EXPRESSION | FIBROBLASTS | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Pancreas - cytology | Blood Cells - metabolism | Cell Dedifferentiation | Male | Gene Expression Profiling | SOXB1 Transcription Factors - metabolism | Teratoma - metabolism | Embryoid Bodies - metabolism | Octamer Transcription Factor-3 - genetics | Blood Cells - cytology | Embryoid Bodies - cytology | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Female | Trophoblasts - cytology | Induced Pluripotent Stem Cells - cytology | Totipotent Stem Cells - cytology | Totipotent Stem Cells - metabolism | Cellular Reprogramming - genetics | Induced Pluripotent Stem Cells - metabolism | Cell Separation | Mice, Inbred C57BL | Cells, Cultured | Kidney - cytology | Transcriptome - genetics | Organ Specificity | Proto-Oncogene Proteins c-myc - metabolism | Ectoderm - cytology | Teratoma - pathology | Animals | Octamer Transcription Factor-3 - metabolism | Stomach - cytology | Teratoma - genetics | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Kruppel-Like Transcription Factors - genetics | Intestines - cytology | Physiological aspects | Cell research | Nuclear reprogramming | Research | Embryonic stem cells | Regenerative medicine | Transplants & implants | Bone marrow | Rodents | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 9, p. e107308
The inner cell mass (ICM) and trophoblast cell lineages duet early embryonic development in mammals. After implantation, the ICM forms the embryo proper as... 
DERIVATION | INHIBITION | GENE | MULTIDISCIPLINARY SCIENCES | MOUSE EMBRYOS | FGF-4 | SELF-RENEWAL | DIFFERENTIATION | INDUCTION | EXPRESSION | Embryonic Stem Cells - metabolism | Ectoderm - drug effects | Embryo Implantation - drug effects | Heterocyclic Compounds, 3-Ring - pharmacology | Humans | Fibroblast Growth Factor 2 - pharmacology | Blastocyst - physiology | Ectoderm - physiology | Cell Lineage - drug effects | Culture Media - metabolism | Trophoblasts - drug effects | Ectoderm - metabolism | Female | Cell Differentiation - physiology | Amides - pharmacology | Embryo Implantation - physiology | Trophoblasts - metabolism | Placenta - physiology | Blastocyst - metabolism | Embryonic Development - physiology | Blastocyst - drug effects | Embryonic Stem Cells - physiology | Cell Lineage - physiology | Placenta - metabolism | Pregnancy | Animals | Activins - pharmacology | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Trophoblasts - physiology | Mice | Pyridines - pharmacology | Embryonic Development - drug effects | Fibroblast growth factors | Stem cells | Cell culture | Ectoderm | Laboratories | Science | Stem cell transplantation | Derivation | CDX2 protein | Kinases | Proteins | Embryogenesis | CDH1 protein | Fibroblasts | Giant cells | Growth factors | Fibroblast growth factor 2 | Developmental biology | Fetuses | Implantation | Blastocysts | Gene expression | Chemical compounds | Embryos | Molecular chains | Embryonic growth stage | Placenta | Morphology | Activin | Pluripotency
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, p. e0177994
Although human term placenta-derived primary cytotrophoblasts (pCTBs) represent a good human syncytiotrophoblast (STB) model, in vitro culture of pCTBs is not... 
CYTOTROPHOBLASTS | MODELS | MULTIDISCIPLINARY SCIENCES | E-CADHERIN | ACTIN CYTOSKELETON | SYNCYTIN | HUMAN CHORIONIC-GONADOTROPIN | EXPRESSION | CULTURE | LINES | CELL-FUSION | Amides - pharmacology | Apoptosis - drug effects | Humans | Trophoblasts - enzymology | Cells, Cultured | Trophoblasts - pathology | Placenta - enzymology | Cell Adhesion - drug effects | rho-Associated Kinases - antagonists & inhibitors | Placenta - drug effects | Pregnancy | Trophoblasts - drug effects | Cell Differentiation - drug effects | Placenta - pathology | Female | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Physiological aspects | Trophoblast | Enzyme inhibitors | Cell differentiation | Growth | Health aspects | Coils | Reproductive health | Protein kinase A | Cell culture | Cornea | Embryo cells | Childrens health | Adhesion tests | Staining | Cell fusion | Kinases | Cell adhesion & migration | Proteins | Trophoblasts | Epidermal growth factor | Immunology | Plates | Medical research | Enzymes | Deoxyribonuclease | Achievement tests | Cultures | Rac1 protein | Gene expression | Botulinum toxin | Adhesion | Rho-associated kinase | Endothelial cells | Medicine | Studies | Trypsin | Placenta | Inhibitors | Stem cells | Rocks | Histocompatibility antigen HLA | Differentiation | Immunofluorescence | In vitro methods and tests | Viability | Apoptosis
Journal Article