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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2016, Volume 113, Issue 8, pp. 2306 - 2311
Journal Article
Biochemistry, ISSN 0006-2960, 07/2017, Volume 56, Issue 26, pp. 3403 - 3413
Journal Article
Circulation Research, ISSN 0009-7330, 07/2007, Volume 101, Issue 2, pp. 185 - 194
We created knock-in mice in which a deletion of 3 base pairs coding for K210 in cardiac troponin (cTn)T found in familial dilated cardiomyopathy patients was... 
Troponin | Knock-in mouse | Mutation | Calcium sensitivity | Dilated cardiomyopathy | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCYTES | T MUTANTS | knock-in mouse | MECHANISMS | PREVALENCE | DELETION | calcium sensitivity | HEART | mutation | HYPERTROPHIC CARDIOMYOPATHY | troponin | FREQUENCY | PERIPHERAL VASCULAR DISEASE | PROTEINS | HEMATOLOGY | EXPRESSION | dilated cardiomyopathy | Sequence Deletion | Cardiomyopathy, Dilated - pathology | Calcium - metabolism | Muscle Contraction - genetics | Humans | Genetic Diseases, Inborn - genetics | Genetic Diseases, Inborn - pathology | Muscle Fibers, Skeletal - metabolism | Pyridazines - pharmacology | Cell Membrane Permeability - genetics | Sarcomeres - pathology | Cardiotonic Agents - therapeutic use | Cardiomyopathy, Dilated - drug therapy | Mice, Mutant Strains | Sarcomeres - genetics | Myocardium - metabolism | Genetic Diseases, Inborn - metabolism | Pyridazines - therapeutic use | Disease Models, Animal | Cardiomyopathy, Dilated - genetics | Amino Acid Sequence | Sarcomeres - metabolism | Myocardium - pathology | Cardiotonic Agents - pharmacology | Troponin C - metabolism | Cardiomyopathy, Dilated - metabolism | Troponin C - genetics | Mice, Knockout | Animals | Cardiomyopathy, Dilated - physiopathology | Muscle Contraction - drug effects | Cell Membrane Permeability - drug effects | Death, Sudden, Cardiac - pathology | Muscle Fibers, Skeletal - pathology | Genetic Diseases, Inborn - physiopathology | Mice | Genetic Diseases, Inborn - drug therapy
Journal Article
FEBS Letters, ISSN 0014-5793, 05/2014, Volume 588, Issue 10, pp. 1935 - 1941
Androgen reduces fat mass, although the underlying mechanisms are unknown. Here, we examined the effect of testosterone on heat production and mitochondrial... 
Testosterone | Mitochondrial biogenesis | Skeletal muscle | Androgen receptor deficient mice | ANDROGEN RECEPTOR | ACTIVATED RECEPTOR-GAMMA | ADIPOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN SENSITIVITY | CELL BIOLOGY | OBESITY | BIOPHYSICS | MASS | MEN | LATE-ONSET | HYPOGONADISM | EXPRESSION | Myoglobin - metabolism | Troponin - genetics | Mitochondria, Muscle - metabolism | Myoglobin - genetics | Body Weight - drug effects | Male | Muscle, Skeletal - metabolism | Receptors, Androgen - deficiency | Cytochromes c - genetics | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Weight Loss - drug effects | Muscle, Skeletal - cytology | Testosterone - pharmacology | Nuclear Respiratory Factor 1 - genetics | Testosterone - metabolism | DNA, Mitochondrial - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Nuclear Respiratory Factor 1 - metabolism | Mitochondria, Muscle - genetics | Troponin - metabolism | Cell Line | DNA, Mitochondrial - metabolism | Cytochromes c - metabolism | Mice, Inbred C57BL | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Eating - drug effects | Animals | Receptors, Androgen - genetics | Androgens - pharmacology | Muscle Fibers, Skeletal - cytology | Mice | Androgens - metabolism | Blood Glucose - metabolism | Energy Metabolism - drug effects | Muscles | Biosynthesis | Body weight | Weight loss
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0181461
Irisin is a myokine encoded in its precursor fibronectin type III domain containing 5 (FNDC5). It is abundantly expressed in cardiac and skeletal muscle, and... 
FNDC5 | MESSENGER-RNA EXPRESSION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MYOSTATIN | TROPONIN-T | SECRETORY ORGAN | HUMAN SKELETAL-MUSCLE | EXERCISE | ADIPOSE-TISSUE | Troponin T - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | Zebrafish Proteins - metabolism | Down-Regulation | Heart - physiology | RNA, Messenger - genetics | Peptides - genetics | Muscle, Skeletal - metabolism | Peptides - deficiency | RNA, Messenger - metabolism | Troponin C - genetics | Zebrafish - genetics | Gene Knockdown Techniques | Zebrafish Proteins - deficiency | Animals | Peptides - metabolism | Zebrafish - metabolism | Myocytes, Cardiac - metabolism | Myostatin - genetics | Zebrafish - physiology | Zebrafish Proteins - genetics | Muscles | Physiological aspects | Myostatin | Messenger RNA | Research | Zebra fish | Veterinary colleges | Heart attacks | Laboratories | Cardiomyopathy | Tissues | Veterinary medicine | Modulators | Fibronectin | Proteins | Exercise | Coding | Rodents | Calcium-binding protein | Physiology | Heart diseases | Cardiovascular system | Cytokines | Cardiac muscle | Immunomodulation | Zebrafish | siRNA | Metabolism | Gene expression | Skeletal muscle | Heart rate | Musculoskeletal system | Troponin | Stem cells | Diabetes | Immunoreactivity | Cardiac output | In vitro methods and tests | Troponin C | Endocrinology
Journal Article