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BioMetals, ISSN 0966-0844, 4/2017, Volume 30, Issue 2, pp. 313 - 320
Gold compounds form a new class of promising metal-based drugs with a number of potential therapeutic applications, particularly in the fields of anticancer... 
Life Sciences | Biochemistry, general | Cysteine proteases | Gold compounds | Microbiology | Enzyme inhibition | Plant Physiology | Parasitic protozoa | Pharmacology/Toxicology | Medicine/Public Health, general | Cell Biology | DRUG-SENSITIVITY | TRYPANOSOMA-BRUCEI-RHODESIENSE | ASSAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | IN-VITRO | LEISHMANIA-MEXICANA | CATHEPSIN-L | ROLES | PARASITE | Cysteine Endopeptidases - chemistry | Plasmodium falciparum - enzymology | Fibroblasts - enzymology | Protozoan Proteins - antagonists & inhibitors | Humans | Cathepsin B - chemistry | Plasmodium falciparum - drug effects | Trypanosoma brucei brucei - enzymology | Trypanosoma cruzi - enzymology | Leishmania infantum - growth & development | Cysteine Proteinase Inhibitors - chemical synthesis | Inhibitory Concentration 50 | Trypanosoma brucei rhodesiense - growth & development | Antiprotozoal Agents - chemical synthesis | Protozoan Proteins - chemistry | Trypanosoma brucei brucei - growth & development | Cell Line | Organogold Compounds - chemical synthesis | Cathepsin B - antagonists & inhibitors | Proteasome Endopeptidase Complex - chemistry | Recombinant Proteins - chemistry | Macrophages - cytology | Cathepsin L - antagonists & inhibitors | Antiprotozoal Agents - pharmacology | Trypanosoma brucei brucei - drug effects | Leishmania infantum - enzymology | Macrophages - enzymology | Animals | Trypanosoma cruzi - growth & development | Organogold Compounds - pharmacology | Cysteine Proteinase Inhibitors - pharmacology | Fibroblasts - drug effects | Leishmania infantum - drug effects | Trypanosoma cruzi - drug effects | Macrophages - drug effects | Fibroblasts - cytology | Mice | Trypanosoma brucei rhodesiense - drug effects | Plasmodium falciparum - growth & development | Cathepsin L - chemistry | Trypanosoma brucei rhodesiense - enzymology | Cysteine | Biological products | Protease inhibitors | Proteases | Parasitic diseases | Antiparasitic agents | Technical education | Cystine | Gold | Enzymes | Antimicrobial agents | Cancer therapies | Pharmaceuticals
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2006, Volume 116, Issue 10, pp. 2739 - 2747
In this study we investigated why bloodstream forms of Trypanosoma brucei gambiense cross human brain microvascular endothelial cells (BMECs), a human... 
Leucine - pharmacology | Blood-Brain Barrier - cytology | Calcium - metabolism | Calcium Signaling - physiology | Humans | Pyrrolidinones - pharmacokinetics | Cell Communication - physiology | Culture Media, Conditioned - pharmacology | Trypanosoma brucei brucei - enzymology | Vinyl Compounds - pharmacology | Cell Movement - physiology | Endothelial Cells - parasitology | Cysteine Endopeptidases - metabolism | Protozoan Proteins - metabolism | Trypanosoma brucei rhodesiense - metabolism | Egtazic Acid - analogs & derivatives | Estrenes - pharmacokinetics | Blood-Brain Barrier - parasitology | Trypanosoma - enzymology | Leucine - analogs & derivatives | Cathepsins - antagonists & inhibitors | Trypanosoma brucei brucei - metabolism | Endothelial Cells - metabolism | Trypanosoma brucei gambiense - metabolism | Dipeptides - pharmacology | Cells, Cultured | Blood-Brain Barrier - metabolism | Naphthalenes - pharmacology | Cell Movement - drug effects | Animals | Egtazic Acid - pharmacology | Trypanosoma - metabolism | Calcium Signaling - drug effects | Cathepsins - metabolism | Endothelial Cells - cytology | Cysteine Proteinase Inhibitors - pharmacology | Cell Communication - drug effects | Trypanosoma brucei gambiense - enzymology | Trypanosoma brucei rhodesiense - enzymology | Cathepsins | Research | Trypanosoma brucei | Analysis
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2012, Volume 55, Issue 20, pp. 8745 - 8756
Journal Article
Molecular & Biochemical Parasitology, ISSN 0166-6851, 2001, Volume 118, Issue 1, pp. 61 - 73
Journal Article
Parasitology International, ISSN 1383-5769, 2010, Volume 59, Issue 4, pp. 560 - 564
Abstract Trypanosoma brucei rhodesiense and T. b. gambiense are known causes of human African trypanosomiasis (HAT), or “sleeping sickness,” which is deadly if... 
Infectious Disease | Gastroenterology and Hepatology | Chemotherapy | Sleeping sickness | Human African Trypanosomiasis | Trypanosome alternative oxidase | COMPLEX | EFFICACY | NORMAL HUMAN-SERUM | ATOVAQUONE | RESISTANCE | GAMBIENSE | AFRICAN TRYPANOSOMIASIS | PLASMODIUM-BERGHEI | PARASITE | PARASITOLOGY | CYTOCHROME-B GENE | Oxidoreductases - antagonists & inhibitors | Trypanosomiasis, African - drug therapy | Parasitic Sensitivity Tests | Protozoan Proteins - antagonists & inhibitors | Humans | Molecular Sequence Data | Mitochondrial Proteins | Protozoan Proteins - genetics | Trypanosoma brucei brucei - enzymology | Oxidoreductases - chemistry | Sesquiterpenes - therapeutic use | Protozoan Proteins - metabolism | Trypanosoma brucei gambiense - genetics | Trypanosoma brucei gambiense - drug effects | Conserved Sequence | Protozoan Proteins - chemistry | Trypanosoma brucei rhodesiense - genetics | Amino Acid Sequence | Oxidoreductases - metabolism | Oxidoreductases - genetics | Enzyme Inhibitors - pharmacology | Trypanosoma brucei brucei - genetics | Enzyme Inhibitors - therapeutic use | Sequence Analysis, DNA | Trypanosoma brucei brucei - drug effects | Trypanosomiasis, African - parasitology | Sequence Alignment | Animals | Trypanosoma brucei brucei - classification | Plant Proteins | Trypanosoma brucei rhodesiense - drug effects | Sesquiterpenes - pharmacology | Trypanosoma brucei gambiense - enzymology | Trypanosoma brucei rhodesiense - enzymology | Oxidases | Trypanosomiasis | Health aspects
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2008, Volume 52, Issue 1, pp. 211 - 219
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 08/2004, Volume 48, Issue 8, pp. 2937 - 2950
Journal Article
Journal Article
Chemical Biology & Drug Design, ISSN 1747-0277, 01/2016, Volume 87, Issue 1, pp. 154 - 158
Journal Article
Journal Article