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Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 32, pp. 19987 - 19998
The eukaryotic protozoan parasite Trypanosoma brucei is the causative agent of human African trypanosomiasis. Polyamine biosynthesis is essential in T. brucei,... 
YEAST | FACTOR EF-P | HUMAN AFRICAN TRYPANOSOMIASIS | BLOOD-STREAM FORMS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HOMOLOG | ACTIN CYTOSKELETON | CELL-GROWTH | HYPUSINE MODIFICATION | SACCHAROMYCES-CEREVISIAE | POLYAMINE METABOLISM | RNA, Protozoan - genetics | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Proteome - genetics | Protozoan Proteins - antagonists & inhibitors | Humans | Molecular Sequence Data | Protozoan Proteins - genetics | RNA, Messenger - metabolism | Gene Knockdown Techniques | Peptides - metabolism | Protozoan Proteins - metabolism | RNA, Messenger - antagonists & inhibitors | Escherichia coli - metabolism | Lysine - metabolism | Microfilament Proteins - metabolism | Flagella - genetics | Peptide Initiation Factors - antagonists & inhibitors | Microfilament Proteins - genetics | RNA-Binding Proteins - antagonists & inhibitors | Recombinant Proteins - metabolism | Amino Acid Sequence | Lysine - analogs & derivatives | Flagella - ultrastructure | Trypanosoma brucei brucei - metabolism | RNA, Messenger - genetics | RNA, Protozoan - antagonists & inhibitors | Recombinant Proteins - genetics | Trypanosoma brucei brucei - genetics | Peptide Initiation Factors - metabolism | Sequence Homology, Amino Acid | Peptide Initiation Factors - genetics | RNA, Protozoan - metabolism | Trypanosoma brucei brucei - ultrastructure | Sequence Alignment | Animals | Flagella - metabolism | Escherichia coli - genetics | Protein Processing, Post-Translational | Proteome - metabolism | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | parasite metabolism | polyamine | spermidine | hypusine | Microbiology | eukaryotic initiation factor 5A (eIF5A) | Trypanosoma brucei
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2016, Volume 60, Issue 4, pp. 2532 - 2536
Journal Article
PLoS pathogens, ISSN 1553-7366, 11/2018, Volume 14, Issue 11, p. e1007412
The bloodstream forms of Trypanosoma brucei (BSF), the parasite protist causing sleeping sickness, primarily proliferate in the blood of their mammalian hosts.... 
PROCYCLIC FORM | TSETSE-FLY GLOSSINA | ALTERNATIVE OXIDASE | MUSCLE | MICROBIOLOGY | IDENTIFICATION | PROLINE METABOLISM | MICRODIALYSIS | VIROLOGY | GENE | CARBOHYDRATE-METABOLISM | PARASITOLOGY | ADIPOSE-TISSUE | Cell Line - metabolism | Metabolomics | Trypanosoma brucei brucei - metabolism | Mitochondria - metabolism | Adipose Tissue - metabolism | Glycerol - metabolism | Succinic Acid - metabolism | Trypanosoma brucei brucei - pathogenicity | Glucose - metabolism | Glycolysis | Culture Media - chemistry | Tandem Mass Spectrometry - methods | Gluconeogenesis | Glycerin | Glycerol | Glucose metabolism | Research | Trypanosoma brucei | Growth | Phosphates | Adaptations | Hexose | Phosphorylation | Adipose tissue | Nuclear magnetic resonance--NMR | Dihydroxyacetone | Glucose kinase | Laboratories | Oxidase | Dihydroxyacetone phosphate | Alternative oxidase | Parasites | Glucose | Adipocytes | Kinases | Western blotting | Proteins | Mitochondria | Supervision | African trypanosomiasis | Carbon sources | Vector-borne diseases | Protozoa | Enzymes | RNA-mediated interference | Cloning | Mass spectroscopy | Metabolism | Carbon | Terminal oxidase | Glycerol kinase | Proteomics | Skin | Acetic acid | Mass spectrometry | Niches | Life Sciences | Microbiology and Parasitology | Parasitology | Nuclear magnetic resonance | NMR
Journal Article
by Matthew Berriman and Elodie Ghedin and Christiane Hertz-Fowler and Gaëlle Blandin and Hubert Renauld and Daniella C. Bartholomeu and Nicola J. Lennard and Elisabet Caler and Nancy E. Hamlin and Brian Haas and Ulrike Böhme and Linda Hannick and Martin A. Aslett and Joshua Shallom and Lucio Marcello and Lihua Hou and Bill Wickstead and U. Cecilia M. Alsmark and Claire Arrowsmith and Rebecca J. Atkin and Andrew J. Barron and Frederic Bringaud and Karen Brooks and Mark Carrington and Inna Cherevach and Tracey-Jane Chillingworth and Carol Churcher and Louise N. Clark and Craig H. Corton and Ann Cronin and Rob M. Davies and Jonathon Doggett and Appolinaire Djikeng and Tamara Feldblyum and Mark C. Field and Audrey Fraser and Ian Goodhead and Zahra Hance and David Harper and Barbara R. Harris and Heidi Hauser and Jessica Hostetler and Al Ivens and Kay Jagels and David Johnson and Justin Johnson and Kristine Jones and Arnaud X. Kerhornou and Hean Koo and Natasha Larke and Scott Landfear and Christopher Larkin and Vanessa Leech and Alexandra Line and Angela Lord and Annette MacLeod and Paul J. Mooney and Sharon Moule and David M. A. Martin and Gareth W. Morgan and Karen Mungall and Halina Norbertczak and Doug Ormond and Grace Pai and Chris S. Peacock and Jeremy Peterson and Michael A. Quail and Ester Rabbinowitsch and Marie-Adele Rajandream and Chris Reitter and Steven L. Salzberg and Mandy Sanders and Seth Schobel and Sarah Sharp and Mark Simmonds and Anjana J. Simpson and Luke Tallon and C. Michael R. Turner and Andrew Tait and Adrian R. Tivey and Susan Van Aken and Danielle Walker and David Wanless and Shiliang Wang and Brian White and Owen White and Sally Whitehead and John Woodward and Jennifer Wortman and Mark D. Adams and T. Martin Embley and Keith Gull and Elisabetta Ullu and J. David Barry and Alan H. Fairlamb and Fred Opperdoes and Barclay G. Barrell and John E. Donelson and Neil Hall and Claire M. Fraser and ...
Science, ISSN 0036-8075, 7/2005, Volume 309, Issue 5733, pp. 416 - 422
African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan Africa. We present the sequence and analysis of the 11... 
Enzymes | Pseudogenes | Genes | Actins | Cytoskeleton | Genomes | Parasitism | Research Articles | Parasites | Metabolism | Chromosomes | ANTIGENIC VARIATION | METABOLISM | MULTIDISCIPLINARY SCIENCES | SEQUENCE | GENES | PARASITIC PROTOZOA | SLEEPING SICKNESS | DRUG TARGET | LEISHMANIA-DONOVANI | CHEMOTHERAPY | TELOMERES | Antigens, Protozoan - immunology | Genome, Protozoan | Glycosylphosphatidylinositols - biosynthesis | Glutathione - metabolism | Humans | Spermidine - analogs & derivatives | Spermidine - metabolism | Molecular Sequence Data | Genes, Protozoan | Pyrimidines - biosynthesis | Protozoan Proteins - genetics | Trypanosoma brucei brucei - chemistry | Amino Acids - metabolism | Protozoan Proteins - metabolism | Chromosomes - genetics | Recombination, Genetic | Protozoan Proteins - chemistry | Antigens, Protozoan - genetics | Cytoskeleton - chemistry | Antigens, Protozoan - chemistry | Antigenic Variation | Glutathione - analogs & derivatives | Trypanosoma brucei brucei - metabolism | Purines - metabolism | Carbohydrate Metabolism | Cytoskeleton - genetics | Ergosterol - biosynthesis | Lipid Metabolism | Trypanosoma brucei brucei - genetics | Sequence Analysis, DNA | Protein Transport | Trypanosomiasis, African - parasitology | Animals | Cytoskeleton - physiology | Trypanosoma brucei brucei - immunology | Genetic aspects | Trypanosoma | Sleep disorders | Glycoproteins | Genomics
Journal Article
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 11/2008, Volume 4, Issue 8, pp. 1079 - 1082
We recently reported the identification and characterization of a novel BH3-only pro-death protein, apolipoprotein L1 (ApoL1), that, when overexpressed,... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Autophagic cell death | Schizophrenia | SNPs | PIPs | Cardiolipin | Autophagy | BH3-only protein | Lipid binding | Apolipoprotein L1 (ApoL1) | Phosphatidic acid | Trypanosomal lytic factor
Journal Article