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1. Full Text Nifurtimox-Eflornithine Combination Therapy for Second-Stage Gambiense Human African Trypanosomiasis: Médecins Sans Frontières Experience in the Democratic Republic of the Congo
by Emilie Alirol and David Schrumpf and Josué Amici Heradi and Andrea Riedel and Catherine de Patoul and Michel Quere and François Chappuis
Clinical infectious diseases, ISSN 1058-4838, 1/2013, Volume 56, Issue 2, pp. 195 - 203
Headache | Relapse | Vomiting | Mortality | Clinical trials | Hats | Children | Cerebrospinal fluid | ARTICLES AND COMMENTARIES | African trypanosomiasis | Trypanosome | human african trypanosomiasis | NECT | pharmacovigilance | Democratic Republic of Congo | safety | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Infectious diseases | Parasitic diseases | Pharmacology. Drug treatments | Protozoal diseases | Biological and medical sciences | Antiparasitic agents | Human protozoal diseases | Medical sciences | Trypanosomiasis | Antibiotics. Antiinfectious agents. Antiparasitic agents | Trypanosomiasis, African - drug therapy | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Child, Preschool | Eflornithine - adverse effects | Infant | Male | Treatment Outcome | Eflornithine - therapeutic use | Trypanosoma brucei gambiense | Young Adult | Medication Adherence | Nifurtimox - adverse effects | Adolescent | Adult | Female | Democratic Republic of the Congo | Drug Therapy, Combination | Child | Nifurtimox - therapeutic use | Cohort Studies | Patient safety | Pharmacology | Drug therapy | Medical treatment | Index Medicus | Side effects | Hospitals
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2. Full Text Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial
by Priotto, Gerardo, Dr and Kasparian, Serena, MD and Mutombo, Wilfried, MD and Ngouama, Daniel, MD and Ghorashian, Sara, MD and Arnold, Ute, MD and Ghabri, Salah, PhD and Baudin, Elisabeth, MD and Buard, Vincent, MD and Kazadi-Kyanza, Serge, MD and Ilunga, Médard, MD and Mutangala, Willy, MD and Pohlig, Gabriele, PhD and Schmid, Caecilia, PhD and Karunakara, Unni, PhD and Torreele, Els, PhD and Kande, Victor, MD
The Lancet (British edition), ISSN 0140-6736, 2009, Volume 374, Issue 9683, pp. 56 - 64
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | General aspects | Infectious diseases | Parasitic diseases | Protozoal diseases | Biological and medical sciences | Human protozoal diseases | Medical sciences | Trypanosomiasis | Trypanosomiasis, African - drug therapy | Trypanocidal Agents - adverse effects | Follow-Up Studies | Humans | Eflornithine - adverse effects | Male | Eflornithine - therapeutic use | Fever - chemically induced | Infection - chemically induced | Seizures - chemically induced | Trypanosomiasis, African - diagnosis | Trypanosomiasis, African - epidemiology | Congo - epidemiology | Adult | Female | Trypanocidal Agents - therapeutic use | Safety | Drug Therapy, Combination | Drug Administration Schedule | Administration, Oral | Kaplan-Meier Estimate | Treatment Outcome | Trypanosoma brucei gambiense | Democratic Republic of the Congo - epidemiology | Animals | Nifurtimox - adverse effects | Infusions, Intravenous | Nifurtimox - therapeutic use | Evaluation | Drug therapy, Combination | Drug therapy | African trypanosomiasis | Drugs | Data analysis | Disease | Research methodology | Clinical trials | Clinical medicine | Tropical diseases | Index Medicus | Abridged Index Medicus
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3. Full Text Recent Developments in Drug Discovery for Leishmaniasis and Human African Trypanosomiasis
by Nagle, Advait S and Khare, Shilpi and Kumar, Arun Babu and Supek, Frantisek and Buchynskyy, Andriy and Mathison, Casey J. N and Chennamaneni, Naveen Kumar and Pendem, Nagendar and Buckner, Frederick S and Gelb, Michael H and Molteni, Valentina
Chemical reviews, ISSN 0009-2665, 11/2014, Volume 114, Issue 22, pp. 11305 - 11347
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Trypanosomiasis - drug therapy | Humans | Drug Design | Antiprotozoal Agents - chemical synthesis | Leishmaniasis - drug therapy | Antiprotozoal Agents - chemistry | Antiprotozoal Agents - therapeutic use | Medical research | Disease | Drug therapy | Epidemiology | Index Medicus | Review
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4. Full Text Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial
by Mesu, Victor Kande Betu Ku and Kalonji, Wilfried Mutombo and Bardonneau, Clélia and Mordt, Olaf Valverde and Blesson, Séverine and Simon, François and Delhomme, Sophie and Bernhard, Sonja and Kuziena, Willy and Lubaki, Jean-Pierre Fina and Vuvu, Steven Lumeya and Ngima, Pathou Nganzobo and Mbembo, Hélène Mahenzi and Ilunga, Médard and Bonama, Augustin Kasongo and Heradi, Josué Amici and Solomo, Jean Louis Lumaliza and Mandula, Guylain and Badibabi, Lewis Kaninda and Dama, Francis Regongbenga and Lukula, Papy Kavunga and Tete, Digas Ngolo and Lumbala, Crispin and Scherrer, Bruno and Strub-Wourgaft, Nathalie and Tarral, Antoine
The Lancet (British edition), ISSN 0140-6736, 01/2018, Volume 391, Issue 10116, pp. 144 - 154
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Trypanosomiasis, African - drug therapy | Drug Administration Schedule | Administration, Oral | Humans | Middle Aged | Male | Treatment Outcome | Trypanosoma brucei gambiense | Nitroimidazoles - therapeutic use | Trypanosomiasis, African - diagnosis | Trypanosomiasis, African - mortality | Adult | Female | Trypanocidal Agents - therapeutic use | Democratic Republic of the Congo | Drug Therapy, Combination | Nifurtimox - therapeutic use | Vector-borne diseases | Drugs | Lymphatic system | Clinical trials | Parasites | Evidence-based medicine | Blood | Tropical diseases | Studies | Parasitic diseases | Drug therapy | Drug dosages | African trypanosomiasis | Index Medicus | Abridged Index Medicus
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5. Full Text Antiparasitic Therapy
by Kappagoda, Shanthi, MD, SM and Singh, Upinder, MD and Blackburn, Brian G., MD
Mayo Clinic proceedings, ISSN 0025-6196, 2011, Volume 86, Issue 6, pp. 561 - 583
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | Antiparasitic agents | General aspects | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Trypanosomiasis, African - drug therapy | Toxoplasmosis - drug therapy | Cestode Infections - drug therapy | Humans | Parasitic Diseases - drug therapy | Giardiasis - drug therapy | Leishmaniasis - drug therapy | Nematode Infections - drug therapy | Trematode Infections - drug therapy | Protozoan Infections - drug therapy | Antiparasitic Agents - therapeutic use | Amebiasis - drug therapy | Chagas Disease - drug therapy | Helminthiasis - drug therapy | Malaria - drug therapy | Antiprotozoal Agents - therapeutic use | Anthelmintics - therapeutic use | Drug Resistance | Complications and side effects | Dosage and administration | Drug therapy | Parasitic diseases | Patient outcomes | Index Medicus | Abridged Index Medicus | Symposium on Antimicrobial Therapy
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6. Full Text Human African trypanosomiasis
by Büscher, Philippe and Cecchi, Giuliano and Jamonneau, Vincent and Priotto, Gerardo
The Lancet (British edition), ISSN 0140-6736, 11/2017, Volume 390, Issue 10110, pp. 2397 - 2409
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Severity of Illness Index | Endemic Diseases - statistics & numerical data | Trypanosomiasis, African - drug therapy | World Health Organization | Global Health | Risk Assessment | Humans | Male | Incidence | Travel | Animals | Trypanosomiasis, African - diagnosis | Neglected Diseases - diagnosis | Trypanosomiasis, African - epidemiology | Neglected Diseases - epidemiology | Female | Developing Countries | Trypanosoma brucei gambiense - isolation & purification | Endemic Diseases - prevention & control | Africa South of the Sahara - epidemiology | Travelers | Agricultural societies | Health aspects | Trypanosomiasis | World health | Vector-borne diseases | Drugs | Epidemics | Medical research | Rural areas | Medical treatment | Rural communities | Clinical trials | Parasites | Epidemiology | Disease control | Low level | Migrants | Tourists | Historical account | Parasitic diseases | Travellers | Differential diagnosis | African trypanosomiasis | Vaccines | Expatriates | Mammals | Exports | 20th century | Index Medicus | Abridged Index Medicus
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