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Journal Article
FEBS letters, ISSN 0014-5793, 2013, Volume 587, Issue 5, pp. 398 - 403
Journal Article
Journal Article
Nature chemistry, ISSN 1755-4349, 2015, Volume 7, Issue 2, pp. 160 - 165
Life is sustained by complex systems operating far from equilibrium and consisting of a multitude of enzymatic reaction networks. The operating principles of... 
CIRCUITS | CHEMICAL OSCILLATORS | AMPLIFICATION | DYNAMICS | PATTERNS | SYSTEMS | TIME | CHEMISTRY, MULTIDISCIPLINARY | CYCLE | GEL | Microfluidic Analytical Techniques | Trypsin Inhibitors - chemistry | Biocatalysis | Chymotrypsin - metabolism | Chymotrypsin - chemistry | Polymers - chemistry | Trypsin Inhibitors - metabolism | Trypsin - metabolism | Trypsin - chemistry
Journal Article
PLOS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, p. e0176694
PRSS3/mesotrypsin is an atypical isoform of trypsin, the upregulation of which has been implicated in promoting tumor progression. To date there are no... 
TARGET | METASTASIS | AFFINITY | CIS-TRANS ISOMERIZATION | MULTIDISCIPLINARY SCIENCES | TRYPSIN-INHIBITORS | DEGRADATION | PROTEIN DATA-BANK | CANCER | EXPRESSION | DISCOVERY | Amino Acid Sequence | Diminazene - chemistry | Diminazene - pharmacology | Catalytic Domain | United States | Escherichia coli | Humans | Trypsin Inhibitors - pharmacology | Drug Discovery - methods | Static Electricity | Trypsin - metabolism | Databases, Pharmaceutical | Dose-Response Relationship, Drug | Trypsin Inhibitors - chemistry | Hydrogen Bonding | Trypsin - genetics | Molecular Docking Simulation | Molecular Structure | Trypsin - chemistry | United States Food and Drug Administration | Trypsin inhibitors | Care and treatment | Research | Structure | Cancer | Brain | Cell culture | Regulatory agencies | Parkinson's disease | Peptides | Lung cancer | Nervous system | Metastasis | Crystallography | Data bases | Molecular docking | Metastases | Proteins | Degradation | Angiogenesis | Hepatitis | Bonding | Movement disorders | Enzymes | Neurodegenerative diseases | Macromolecules | Solubility | Proteinase inhibitors | Nucleic acids | Studies | Benzamidine | Immunogenicity | Pancreatic cancer | Isoforms | Ligands | Cell migration | Drugs | Substructures | Animal models | Molecular structure | Laboratories | Colorimetry | Engineering | Databases | Pain | Rodents | Digestive tract | Metamorphosis | Hydrogen ion concentration | Crystal structure | Epidermis | Breast cancer | Permeability | Free energy | Lungs | Natural products | Pharmacokinetics | Prostate cancer | Prostate | x-ray crystallography | protease inhibitor | drug discovery | virtual screening | BASIC BIOLOGICAL SCIENCES | crystal structure | trypsin | mesotrypsin | serine protease | structure-based docking | in-silico screening
Journal Article
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2012, Volume 209, Issue 13, pp. 2395 - 2408
Journal Article
Journal of chemical theory and computation, ISSN 1549-9618, 10/2015, Volume 11, Issue 10, pp. 5002 - 5011
Journal Article
Biophysical journal, ISSN 0006-3495, 02/2016, Volume 110, Issue 3, pp. 550a - 550a
Journal Article
PloS one, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63571
Inhibitors of peptidases isolated from leguminous seeds have been studied for their pharmacological properties. The present study focused on purification,... 
AMINO-ACID-SEQUENCE | MACULATUS COWPEA WEEVIL | CECAL LIGATION | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | SERINE PROTEINASE-INHIBITOR | PURIFICATION | CHYMOTRYPSIN INHIBITOR | URINARY TRYPSIN-INHIBITOR | SEPSIS | PROTEASE INHIBITORS | Plant Extracts - chemistry | Plant Extracts - pharmacology | Escherichia coli - drug effects | Humans | Trypsin Inhibitors - pharmacology | Molecular Sequence Data | Substrate Specificity | Trypsin Inhibitors - isolation & purification | Erythrina - chemistry | Microbial Sensitivity Tests | Sepsis - drug therapy | Trypsin Inhibitors - chemistry | Anticoagulants - chemistry | Plant Proteins - chemistry | Anti-Inflammatory Agents - isolation & purification | Leukocyte Count | Seeds - chemistry | Protein Stability | Drug Evaluation, Preclinical | Anticoagulants - isolation & purification | Plant Proteins - isolation & purification | Amino Acid Sequence | Sepsis - immunology | Plant Proteins - pharmacology | Cytokines - metabolism | Peptides - chemistry | Anti-Inflammatory Agents - pharmacology | Plant Extracts - isolation & purification | Peptides - pharmacology | Sequence Homology, Amino Acid | Cell Movement - drug effects | Peptides - isolation & purification | Animals | Anti-Inflammatory Agents - chemistry | Chromatography, Affinity | Anticoagulants - pharmacology | Mice | Mice, Inbred BALB C | Trypsin - chemistry | Hydrogen-Ion Concentration | Enzymes | Seeds | Ammonium sulphate | Analysis | Thrombin | Hydrolases | Anticoagulants (Medicine) | High performance liquid chromatography | Trypsin inhibitors | Blood coagulation | Ammonium | Leukocyte migration | Coagulation | Cytotoxicity | Blood | Clotting | Affinity chromatography | Rodents | Peripheral blood | Elastase | Inhibition | Anticoagulants | Fractionation | Peptidase | Purification | Blood cells | Neutrophils | Amino acid sequence | Mass spectroscopy | Interleukin 12 | Inflammation | Coagulants | Pharmacology | Liquid chromatography | High-performance liquid chromatography | Chromatography | Studies | White blood cells | Chymotrypsin | Peptidases | Properties (attributes) | Ammonium sulfate | Trypsin | Inhibitors | Sepsis | Interferon | Pepsin | Sulfate | Mass spectrometry | Potassium
Journal Article