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Journal of Biological Chemistry, ISSN 0021-9258, 05/2015, Volume 290, Issue 22, pp. 13875 - 13887
Journal Article
Stem Cell Research and Therapy, ISSN 1757-6512, 04/2017, Volume 8, Issue 1, pp. 88 - 88
Background: Liver stem cell therapy (SCT) has been suggested as a promising means to improve liver regeneration in advanced liver disease. However, data from... 
Cirrhosis | Kupffer cell | SPINK1 | Alcoholic hepatitis | HGF | Stem cell transplantation | CD68 | Macrophage | PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | COLONY-STIMULATING FACTOR | REGENERATION | MACROPHAGES | INJURY | PROLIFERATION | CELL BIOLOGY | HEPATITIS | CD34(+) | Liver - pathology | Leukocyte Common Antigens - metabolism | Humans | Middle Aged | Transcriptome | Male | Serum Amyloid A Protein - genetics | Antigens, CD - genetics | Mesenchymal Stem Cell Transplantation - adverse effects | Antigens, CD - metabolism | Mesenchymal Stromal Cells - cytology | Collagen Type I - genetics | Liver Diseases, Alcoholic - therapy | Hepatocyte Growth Factor - genetics | Adult | Female | Collagen Type I - metabolism | Serum Amyloid A Protein - metabolism | Liver - metabolism | Mesenchymal Stromal Cells - metabolism | Antigens, Differentiation, Myelomonocytic - genetics | Hepatocyte Growth Factor - metabolism | Carrier Proteins - genetics | Macrophages - metabolism | Carrier Proteins - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Transplantation, Autologous - adverse effects | Leukocyte Common Antigens - genetics | Aged | Trypsin Inhibitor, Kazal Pancreatic | Liver diseases | Alcohol | Inflammation | Histology | Gene expression | Macrophages | Hepatitis | Cell growth | Immunology | Granulocytes | Hepatology | Rodents | Stem cells | Gastroenterology | Bone marrow | Liver transplantation | Index Medicus
Journal Article
Molecular and Cellular Proteomics, ISSN 1535-9476, 05/2015, Volume 14, Issue 5, pp. 1400 - 1410
The data-independent acquisition (DIA) approach has recently been introduced as a novel mass spectrometric method that promises to combine the high content... 
DRUG-INDUCED HEPATOTOXICITY | ACCURATE | TARGETED MASS-SPECTROMETRY | PEPTIDE IDENTIFICATION | BIOCHEMICAL RESEARCH METHODS | VALIDATION | NORMALIZATION | ABSOLUTE QUANTIFICATION | PROTEINS | DISCOVERY | Glutamate Formimidoyltransferase - metabolism | Oncogene Proteins - genetics | Glutamate Formimidoyltransferase - genetics | Proteome - genetics | Humans | Analgesics, Non-Narcotic - pharmacology | Voltage-Dependent Anion Channel 2 - genetics | Amidinotransferases - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Hepatocytes - metabolism | Peroxiredoxin VI - genetics | Peroxiredoxin VI - metabolism | Liver - drug effects | Acetaminophen - pharmacology | Proteolysis | Peroxiredoxin VI - analysis | Annexin A2 - analysis | Ammonia-Lyases - analysis | Proteomics - methods | Amidinotransferases - analysis | Oncogene Proteins - analysis | Intracellular Signaling Peptides and Proteins - genetics | Hepatocytes - drug effects | Gene Expression | Glutamate Formimidoyltransferase - analysis | Voltage-Dependent Anion Channel 2 - analysis | Ammonia-Lyases - genetics | Tissue Culture Techniques | Liver - metabolism | Intracellular Signaling Peptides and Proteins - analysis | Oncogene Proteins - metabolism | Ammonia-Lyases - metabolism | Proteome - analysis | Voltage-Dependent Anion Channel 2 - metabolism | Amidinotransferases - metabolism | Protein Deglycase DJ-1 | Annexin A2 - genetics | Annexin A2 - metabolism | Proteome - metabolism | Trypsin - chemistry | Peptides - analysis | Index Medicus | Research
Journal Article
Gastroenterology, ISSN 0016-5085, 2009, Volume 137, Issue 1, pp. 350 - 360.e5
Background & Aims Acute pancreatitis constitutes a life-threatening condition in which pancreatic acinar cells undergo massive cell death. We investigated the... 
Gastroenterology and Hepatology | ACTIVATED PROTEIN-KINASE | INHIBITION | RAT PANCREAS | TRYPSINOGEN ACTIVATION | IN-VIVO | ENDOTOXIN | LIPOPOLYSACCHARIDE | CHRONIC ALCOHOL EXPOSURE | ACINAR-CELLS | GASTROENTEROLOGY & HEPATOLOGY | CELL-DEATH | Caspase 9 - metabolism | Pancreatitis - etiology | Humans | Caspase 3 - metabolism | Endotoxemia - chemically induced | Lysosomes - enzymology | Male | Endotoxemia - pathology | Autophagy | Lipopolysaccharides | Necrosis | Lysosomes - metabolism | Transfection | RNA Interference | Time Factors | Adenosine Triphosphate - metabolism | HMGB1 Protein - metabolism | Pancreatitis, Alcoholic - metabolism | Disease Models, Animal | Pancreas - enzymology | Pancreatitis, Alcoholic - etiology | Cell Line | Acute Disease | Lysosome-Associated Membrane Glycoproteins - metabolism | Ethanol | Down-Regulation | Lysosomal-Associated Membrane Protein 2 - genetics | Pancreas - pathology | Rats | Cathepsin B - metabolism | Pancreas - metabolism | Trypsin - metabolism | Rats, Sprague-Dawley | Animals | Endotoxemia - complications | Pancreatitis, Alcoholic - pathology | Pancreatitis - pathology | Pancreatitis - metabolism | Endotoxemia - metabolism | Lysosomal-Associated Membrane Protein 2 - metabolism | Apoptosis | Chromosomal proteins | Mitogens | Pancreatitis | Index Medicus | Abridged Index Medicus
Journal Article
Fish Physiology and Biochemistry, ISSN 0920-1742, 6/2015, Volume 41, Issue 3, pp. 773 - 787
The goal of this study was to systematically evaluate the molecular activities of endocrine-, amino acid and peptide transporters-, and metabolic... 
Life Sciences | Animal Physiology | Animal Biochemistry | Zoology | Freshwater & Marine Ecology | Transporters | Zebrafish | Animal Anatomy / Morphology / Histology | Postprandial starvation | Metabolic enzymes | PHYSIOLOGY | RAINBOW-TROUT | PLASMA GHRELIN LEVELS | BIOCHEMISTRY & MOLECULAR BIOLOGY | APPETITE-REGULATING HORMONES | GROWTH-HORMONE RECEPTOR | LIPOPROTEIN-LIPASE | NEUROPEPTIDE-Y NPY | FISHERIES | STIMULATES FOOD-INTAKE | HEPATIC GLUCOSE-METABOLISM | FACTOR-I AXIS | GLUTAMINE-SYNTHETASE ACTIVITY | Fatty Acid Synthases - metabolism | Leptin - metabolism | DNA Primers - genetics | RNA, Messenger - metabolism | Postprandial Period - physiology | Neuropeptide Y - metabolism | Cholecystokinin - metabolism | Time Factors | Membrane Transport Proteins - genetics | Membrane Transport Proteins - metabolism | Fasting - metabolism | Glutamate Dehydrogenase - metabolism | Glutamate-Ammonia Ligase - metabolism | Lipoprotein Lipase - metabolism | Real-Time Polymerase Chain Reaction | Gene Expression Regulation - physiology | Trypsin - metabolism | Amino Acid Transport Systems - metabolism | Aspartate Aminotransferases - metabolism | Animals | Analysis of Variance | Zebrafish - metabolism | Amino Acid Transport Systems - genetics | Zebrafish - physiology | Alanine Transaminase - metabolism | Feedback, Physiological - physiology | Phosphates | Starvation | Genes | Body weight | Neuropeptides | Aspartate | Lipoprotein lipase | Glucose | Glutamate | Fatty acids | Dextrose | Messenger RNA | Biological diversity conservation | Ligases | Analysis | Aquaculture industry | Leptin | Genetic research | Genetic aspects | Glutamine | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2016, Volume 36, Issue 6, pp. 1101 - 1113
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2006, Volume 281, Issue 16, pp. 10760 - 10768
ATP-binding cassette protein A1 (ABCA1) plays a major role in cholesterol homeostasis and high density lipoprotein metabolism. Apolipoprotein A-I binds to... 
BINDING CASSETTE TRANSPORTER | MULTIDRUG-RESISTANCE PROTEINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHOLESTEROL EFFLUX | EXTRACELLULAR DOMAIN | INORGANIC-PHOSPHATE | NUCLEOTIDE-BINDING | PHOSPHOLIPID EFFLUX | APOLIPOPROTEIN-A-I | HIGH-DENSITY-LIPOPROTEIN | P-GLYCOPROTEIN | Choline - metabolism | Microsomes - metabolism | Chromatography, Ion Exchange | Baculoviridae - metabolism | Humans | Insecta | Lipoproteins, HDL - metabolism | Phosphatidylcholines - metabolism | ATP-Binding Cassette Transporters - physiology | Dose-Response Relationship, Drug | Lipids - chemistry | Trypsin - pharmacology | Time Factors | ATP-Binding Cassette Transporters - metabolism | Sitosterols - chemistry | Cell Membrane - metabolism | Phospholipids - metabolism | ATP Binding Cassette Transporter 1 | Fibroblasts - metabolism | Cell Line | Cholesterol - analogs & derivatives | Detergents - pharmacology | Phosphatidylserines - chemistry | Adenosine Triphosphatases - metabolism | Glycosylation | Glyburide - metabolism | Phosphatidylcholines - chemistry | Cholesterol - metabolism | Sitosterols - metabolism | Liposomes - chemistry | Phosphatidylglycerols - chemistry | Animals | Models, Biological | Sepharose - chemistry | Phytosterols - metabolism | Protein Binding | Genetic Vectors | DNA, Complementary - metabolism | Phosphatidylethanolamines - chemistry | Intracellular Membranes - metabolism | Index Medicus
Journal Article
Journal Article
Journal Article
Laboratory Investigation, ISSN 0023-6837, 2008, Volume 88, Issue 3, pp. 264 - 274
A fine balance between anabolic and catabolic mechanisms maintains extracellular matrix homeostasis in articular cartilage, and shifts toward degradation are... 
MMP | β-catenin signaling | Articular cartilage | Chondrocyte | Wnt | Osteoarthritis | articular cartilage | ENDOCHONDRAL OSSIFICATION | TRANSCRIPTION FACTORS | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATED PROTEIN-KINASE | osteoarthritis | PATHOLOGY | BETA-CATENIN | beta-catenin signaling | DIFFERENTIATED PHENOTYPE | CARTILAGE | chondrocyte | BONE | EXPRESSION | Immunohistochemistry | Chondrocytes - cytology | Luciferases - metabolism | Extracellular Matrix - metabolism | Cytoplasm - metabolism | L Cells (Cell Line) | Proteoglycans - secretion | Wnt Proteins - metabolism | Hemagglutinins - metabolism | Extracellular Matrix - genetics | Cell Nucleus - metabolism | Transfection | Trypsin - pharmacology | Wnt Proteins - genetics | Cartilage, Articular - metabolism | Interleukin-1beta - metabolism | Adenoviridae - genetics | Female | Cell Culture Techniques | Osteoarthritis - pathology | Chondrocytes - metabolism | Genes, Reporter | Disease Models, Animal | Recombinant Proteins - metabolism | Rabbits | Guinea Pigs | Signal Transduction | beta Catenin | Luciferases - analysis | Matrix Metalloproteinase 13 - genetics | Cells, Cultured | Joints - pathology | Matrix Metalloproteinase 3 - metabolism | Proteoglycans - analysis | Cell Separation - methods | Epitopes | Recombinant Proteins - pharmacology | Matrix Metalloproteinase 13 - metabolism | Culture Media, Conditioned | ADAM Proteins - metabolism | Animals | Mice | Wnt Proteins - physiology | ADAM Proteins - genetics | Cartilage, Articular - drug effects | Matrix Metalloproteinase 3 - genetics | Index Medicus
Journal Article