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BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 02/2020, Volume 1865, Issue 2, p. 158543
Dysregulation of the tryptophan (Trp)-NAD pathway has been related to several pathological conditions, and the metabolites in this pathway are known to... 
3-(2,2,2-Trimethylhydrazinium)propionate dihydrate | NAD | Tryptophan biosynthesis and metabolites | Meldonium | CoA | NADH mitochondria | 2-(tridec-12-yn-1-ylthio)acetic acid | Lipid metabolism | 1-Triple TTA | Carnitine
Journal Article
Experimental Gerontology, ISSN 0531-5565, 01/2020, Volume 129, p. 110770
The essential amino acid L-tryptophan (Trp) appears to play an important role in aging by acting as a general regulator of protein homeostasis. The major route... 
Aging | Indoleamine 2,3-dioxygenase | Kynurenine pathway enzymes | Tryptophan 2,3-dioxygenase | Tryptophan binding | Plasma free tryptophan
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3693 - 9
Serotonin has a pivotal function regulating development, growth, reproduction and behavior in animals. In this paper, we studied the deregulatory effects of... 
CRAYFISH | LIFE-HISTORY TRAITS | CHEMICALS | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | NEURONS | DOPAMINE | POLYUNSATURATED FATTY-ACIDS | REUPTAKE INHIBITORS | MAGNA | FLUOXETINE | CRISPR | Energy metabolism | Deregulation | Serotonin | Thyrotropin-releasing hormone | Hydroxylase | Cloning | Tryptophan | Molting | Arachidonic acid | Metabolism | Insulin | Tryptophan hydroxylase | Signal transduction | Metabolic pathways
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 16
Parkinson’s disease (PD) is a chronic disorder that presents a range of premotor signs, such as sleep disturbances and cognitive decline, which are key... 
Parkinson's disease | Phenylalanine | Neurodegenerative diseases | Cognitive ability | Tryptophan | Cognition | Metabolism | Sleep deprivation | Rotenone | Lipoproteins | Mitochondria | Sleep | Biomarkers | Movement disorders | Locomotor activity
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6602 - 9
Amino acid derangements are common in severe falciparum malaria and have been associated with endothelial dysfunction (L-arginine), metabolic acidosis (alanine... 
METABOLISM | MULTIDISCIPLINARY SCIENCES | L-ARGININE | NITRIC-OXIDE | QUININE | DYSFUNCTION | CEREBROSPINAL-FLUID | ENDOTHELIAL FUNCTION | ARTESUNATE | CEREBRAL MALARIA | CHILDREN | Alanine | Malaria | Phenylalanine | Tryptophan | Amino acid sequence | Amino acids | Mass spectroscopy | High-performance liquid chromatography | Metabolites | Arginine | Sepsis | Hypoxia | Lactic acid | Acidosis | Metabolic acidosis
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 1 - 11
The lack of effective treatments and a high rate of relapse in cocaine addiction constitute a major health problem. The present study was conducted to examine... 
RESEARCH INTERVIEW | DEPRESSION | ENDOGENOUS BRAIN LEVELS | TRANSPORTER | MULTIDISCIPLINARY SCIENCES | MENTAL-DISORDERS | DOPAMINE | POLYMORPHISM | UPTAKE SITES | STRESS | EPIDEMIOLOGY | Metabolites | Mental disorders | Addiction | Serotonin | Comorbidity | Tryptophan | Cocaine | Kynurenic acid | Addictions
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 10/2019, Volume 10, Issue 1, pp. 1 - 14
Journal Article
Stress, ISSN 1025-3890, 11/2019, Volume 22, Issue 6, pp. 707 - 717
Transport stress causes not only physiological changes but also behavioral responses, including anxiety-like and depression-like behaviors in animals. The... 
dorsal raphe nucleus | anxiety | Fos | tryptophan hydroxylase 2 | 5-hydroxytryptamine | transport stress
Journal Article