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Nature, ISSN 0028-0836, 10/2011, Volume 478, Issue 7368, pp. 197 - 203
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7508, pp. 184 - 190
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 04/2010, Volume 115, Issue 17, pp. 3520 - 3530
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2012, Volume 109, Issue 37, pp. 14912 - 14917
Toxicity of aggregation-prone proteins is thought to play an important role in aging and age-related neurological diseases like Parkinson and Alzheimer's... 
Protein metabolism | Neurons | Medical genetics | Huntington disease | Homeostasis | Parkinson disease | Metabolic diseases | Gene expression regulation | Alzheimers disease | Human genetics | Huntington | Longevity | LIFE-SPAN | PROTEOTOXICITY | MULTIDISCIPLINARY SCIENCES | HEAT-SHOCK-FACTOR | ALPHA-SYNUCLEIN | CAENORHABDITIS-ELEGANS | KYNURENINE 3-MONOOXYGENASE | IN-VIVO | longevity | C-ELEGANS | LEWY BODIES | PARKINSONS-DISEASE | Tryptophan Oxygenase - antagonists & inhibitors | Animals, Genetically Modified | alpha-Synuclein - toxicity | Computational Biology | Tryptophan - chemistry | Immunoblotting | DNA Primers - genetics | Longevity - genetics | Reverse Transcriptase Polymerase Chain Reaction | Tryptophan - metabolism | Tryptophan Oxygenase - metabolism | Caenorhabditis elegans | Tandem Mass Spectrometry | Fertility - genetics | Animals | Peptides - metabolism | Aging - physiology | RNA Interference | Homeostasis - physiology | Amyloid beta-Peptides - metabolism | Chromatography, Liquid | Aging - metabolism | Proteins | Tryptophan | Physiological aspects | Aging | Research | Health aspects | Enzymes | Metabolites | Nematodes | Cytotoxicity | Index Medicus | Peptides | Neurons and Cognition | Psychology and behavior | Neurobiology | Tryptophan Oxygenase | DNA Primers | Life Sciences | Fertility | Amyloid beta-Peptides | Cognitive Sciences | alpha-Synuclein | Biological Sciences
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 04/2004, Volume 172, Issue 7, pp. 4100 - 4110
Human monocyte-derived dendritic cells (DCs) are capable of expressing the tryptophan-degrading enzyme indoleamine 2,3-dioxygenase (IDO), which allows them to... 
RESPONSES | SERUM-FREE CONDITIONS | INHIBITION | KILLER-CELL | MECHANISM | SUBSETS | ANTIGEN-PRESENTING CELLS | PROLIFERATION | IMMUNOLOGY | INDUCE TOLERANCE | TRYPTOPHAN CATABOLISM | Antigens, CD - immunology | Tryptophan Oxygenase - antagonists & inhibitors | Membrane Glycoproteins - metabolism | T-Lymphocyte Subsets - cytology | Antigens, CD - biosynthesis | Dendritic Cells - immunology | Humans | Membrane Glycoproteins - biosynthesis | Antibodies, Blocking - pharmacology | CD4-Positive T-Lymphocytes - enzymology | Enzyme Induction - immunology | Tryptophan - metabolism | Enzyme Activation - immunology | Tryptophan Oxygenase - physiology | Antigens, CD - metabolism | Lymphocyte Culture Test, Mixed | CD4-Positive T-Lymphocytes - immunology | Immunoconjugates - immunology | B7-2 Antigen | Membrane Glycoproteins - physiology | Tryptophan Oxygenase - biosynthesis | Flow Cytometry | Abatacept | Immunosuppressive Agents - metabolism | B7-1 Antigen - biosynthesis | Membrane Glycoproteins - immunology | B7-1 Antigen - immunology | CD4-Positive T-Lymphocytes - cytology | Cells, Cultured | B7-1 Antigen - physiology | Interferon-gamma - physiology | B7-1 Antigen - metabolism | CD28 Antigens - immunology | Growth Inhibitors - metabolism | Tryptophan Oxygenase - metabolism | Up-Regulation - immunology | Dendritic Cells - enzymology | Down-Regulation - immunology | T-Lymphocyte Subsets - enzymology | Growth Inhibitors - physiology | Antigens, CD - physiology | Ligands | Indoleamine-Pyrrole 2,3,-Dioxygenase
Journal Article