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Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 42, pp. 4867 - 4873
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2004, Volume 173, Issue 10, pp. 6357 - 6365
Bacillus Calmette-Guerin (BCG) vaccine has failed to control the global tuberculosis (TB) epidemic, and there is a lack of safe and effective mucosal vaccines... 
MYCOBACTERIUM-TUBERCULOSIS | ENHANCED IMMUNOGENICITY | IMMUNITY | DNA VACCINES | EFFICACY | SYSTEMIC IMMUNIZATION | CD4(+) T-CELLS | RECENT PROGRESS | INFECTION | IMMUNOLOGY | BCG VACCINES | Vaccines, DNA - genetics | Mycobacterium bovis - immunology | Viral Vaccines - genetics | Mycobacterium tuberculosis - immunology | Vaccines, DNA - immunology | Respiratory Mucosa - virology | Vaccines, Synthetic - immunology | Acyltransferases - genetics | Antigens, Bacterial - biosynthesis | Antigens, Bacterial - genetics | Vaccines, DNA - administration & dosage | Acyltransferases - biosynthesis | CD4-Positive T-Lymphocytes - immunology | Respiratory Mucosa - microbiology | Immunization, Secondary | Injections, Subcutaneous | Respiratory Mucosa - immunology | Adenoviridae - genetics | Female | Tuberculosis Vaccines - immunology | Adenoviridae - immunology | Tuberculosis Vaccines - genetics | Immunity, Cellular - genetics | Tuberculosis Vaccines - administration & dosage | Vaccines, Synthetic - genetics | Injections, Intramuscular | Administration, Intranasal | Tuberculosis, Pulmonary - prevention & control | Viral Vaccines - administration & dosage | Tuberculosis, Pulmonary - immunology | Animals | Mice | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Genetic Vectors | Viral Vaccines - immunology | Mycobacterium tuberculosis - genetics | Tuberculosis, Pulmonary - virology | Index Medicus | Abridged Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 2015, Volume 33, Issue 48, pp. 6800 - 6808
Journal Article
Journal Article
Infection and Immunity, ISSN 0019-9567, 08/2009, Volume 77, Issue 8, pp. 3364 - 3373
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 12/2016, Volume 214, Issue 12, pp. 1996 - 2005
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 12/2015, Volume 99, Issue 24, pp. 10587 - 10595
Tuberculosis (TB) remains one of the most menacing infectious diseases, although attenuated Mycobacterium bovis Bacillus Calmette-Guerin (BCG) vaccine has been... 
Life Sciences | Biotechnology | HspX | Tuberculosis | Microbiology | Microbial Genetics and Genomics | Overexpresssion | Recombinant BCG | Vaccine | Ag85B | IMMUNITY | PROTEIN | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | T-CELLS | Mycobacterium bovis - immunology | Antigens, Bacterial - immunology | Mycobacterium tuberculosis - immunology | Vaccines, Synthetic - immunology | Acyltransferases - genetics | Antigens, Bacterial - biosynthesis | Antigens, Bacterial - genetics | Acyltransferases - biosynthesis | CD4-Positive T-Lymphocytes - immunology | BCG Vaccine - genetics | Vaccines, Attenuated - administration & dosage | Bacterial Proteins - immunology | Mycobacterium bovis - genetics | Disease Models, Animal | Mice, Inbred C57BL | Vaccines, Synthetic - genetics | Bacterial Proteins - genetics | Acyltransferases - immunology | Tuberculosis - immunology | Vaccines, Attenuated - immunology | Animals | Tuberculosis - prevention & control | BCG Vaccine - immunology | Bacterial Proteins - biosynthesis | Vaccines, Synthetic - administration & dosage | CD8-Positive T-Lymphocytes - immunology | BCG Vaccine - administration & dosage | Mycobacterium tuberculosis - genetics | Vaccines, Attenuated - genetics | Prevention | BCG | BCG vaccines | Physiological aspects | Genetic aspects | Research | Studies | Antigens | Pathogens | Analysis | Vaccines | Genetic recombination | Index Medicus
Journal Article
Infection and Immunity, ISSN 0019-9567, 08/2007, Volume 75, Issue 8, pp. 4105 - 4115
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 2/2015, Volume 99, Issue 4, pp. 1817 - 1826
The use of the food-grade bacterium Lactococcus lactis as a vehicle for the oral delivery of DNA vaccine plasmids constitutes a promising strategy for... 
Life Sciences | Biotechnology | Lactococcus lactis | Tuberculosis | Microbiology | ESAT-6 | Microbial Genetics and Genomics | DNA delivery system | Intestinal mucosa | FIBRONECTIN-BINDING PROTEIN | PLASMID | TUBERCULOSIS INFECTION | AG85B | PROTECTIVE EFFICACY | IMMUNOGENICITY | BOVIS BCG | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FUSION PROTEIN | AG85A-ESAT-6-IL-21 | MUCOSAL DELIVERY | Vaccines, DNA - genetics | Spleen - immunology | Antigens, Bacterial - immunology | Mycobacterium tuberculosis - immunology | Colon - immunology | Vaccines, Synthetic - immunology | Antigens, Bacterial - genetics | Vaccines, DNA - administration & dosage | Drug Carriers | Vaccines, Synthetic - isolation & purification | Leukocytes, Mononuclear - immunology | Cloning, Molecular | Bacterial Proteins - immunology | Tuberculosis Vaccines - immunology | Tuberculosis Vaccines - genetics | Lactococcus lactis - genetics | Tuberculosis Vaccines - isolation & purification | Interferon-gamma - secretion | Tuberculosis Vaccines - administration & dosage | Vaccines, Synthetic - genetics | Bacterial Proteins - genetics | Immunoglobulin A, Secretory - analysis | Animals | Feces - chemistry | Plasmids | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | Mycobacterium tuberculosis - genetics | Antigens | Mycobacterium | Usage | Lactococcus | Mycobacteria | DNA vaccines | Production processes | Studies | Analysis | Bacteria | Vaccines | Genetic recombination | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 04/2018, Volume 36, Issue 18, pp. 2462 - 2470
Tuberculosis (TB) infection affects a quarter of the global population resulting in a large burden of TB disease and mortality. The long-term control of TB... 
Tuberculosis | Recombinant influenza A | Mucosal vaccine | Antigen 85B | Protection | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | LUNG | CD8(+) | EFFICACY | BCG | VACCINATION | IMMUNOLOGY | CHALLENGE | IMMUNOGENICITY | T-CELL RESPONSES | AEROSOL | Influenza A virus - genetics | Antigens, Bacterial - immunology | Mycobacterium tuberculosis - immunology | Epitopes, T-Lymphocyte - genetics | Vaccines, Synthetic - immunology | Acyltransferases - genetics | Antigens, Bacterial - genetics | Drug Carriers | CD4-Positive T-Lymphocytes - immunology | Female | Immunization Schedule | Bacterial Proteins - immunology | Epitopes, T-Lymphocyte - immunology | Tuberculosis Vaccines - immunology | Disease Models, Animal | Tuberculosis Vaccines - genetics | Mice, Inbred C57BL | Tuberculosis Vaccines - administration & dosage | Vaccines, Synthetic - genetics | Bacterial Proteins - genetics | Cytokines - secretion | Acyltransferases - immunology | Treatment Outcome | Administration, Intranasal | Tuberculosis, Pulmonary - prevention & control | Animals | Vaccines, Synthetic - administration & dosage | Mycobacterium tuberculosis - genetics | Influenza vaccines | Medical research | Tuberculosis vaccines | Influenza | Medicine, Experimental | T cells | Health aspects | Antigenic determinants | Peptides | Lung | Viruses | Infections | Lymphocytes T | Vaccines | Immunity | Interleukin 2 | Lymphocytes | Recombinant | Spleen | Antigens | Immunization | Cytokines | Glycerol | Durability | T cell receptors | Disease control | CD4 antigen | Lungs | Immunogenicity | Tumor necrosis factor | γ-Interferon | Index Medicus
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2005, Volume 174, Issue 10, pp. 6332 - 6339
Previously we have shown that Ag85B-ESAT-6 is a highly efficient vaccine against tuberculosis. However, because the ESAT-6 Ag is also an extremely valuable... 
MYCOBACTERIUM-TUBERCULOSIS | IMMUNITY | BACILLUS-CALMETTE-GUERIN | PROTEIN | DNA VACCINE | BOVIS | BCG | T-CELL EPITOPES | INFECTION | IMMUNOLOGY | ANTIGEN 85B | Recombinant Fusion Proteins - immunology | Lung - microbiology | Vaccines, DNA - genetics | Vaccines, Subunit - genetics | Antigens, Bacterial - immunology | Vaccines, DNA - immunology | Molecular Sequence Data | Colony Count, Microbial | Acyltransferases - genetics | Antigens, Bacterial - genetics | Vaccines, DNA - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Acyltransferases - administration & dosage | Base Sequence | Female | Bacterial Proteins - immunology | Epitopes, T-Lymphocyte - immunology | Tuberculosis Vaccines - immunology | Recombinant Fusion Proteins - administration & dosage | Tuberculosis Vaccines - genetics | Amino Acid Sequence | CD4-Positive T-Lymphocytes - microbiology | Mice, Inbred C57BL | Tuberculosis Vaccines - administration & dosage | Bacterial Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Acyltransferases - immunology | Antigens, Bacterial - administration & dosage | Vaccines, Subunit - immunology | Tuberculosis, Pulmonary - prevention & control | Bacterial Proteins - administration & dosage | Tuberculosis, Pulmonary - immunology | Animals | Tuberculosis, Pulmonary - diagnosis | Vaccines, Subunit - administration & dosage | Recombinant Fusion Proteins - genetics | Mice | Mice, Inbred BALB C | Epitopes, T-Lymphocyte - metabolism | Interferon-gamma - biosynthesis | Lung - immunology | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54708 - e54708
Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the leading fatal infectious diseases. The development of TB vaccines has been recognized as a... 
TOXIN-B-SUBUNIT | MYCOBACTERIUM-TUBERCULOSIS | HEAT-LABILE ENTEROTOXIN | THERAPEUTIC PROTEINS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | FUSION PROTEIN | ORAL DELIVERY | CHOLERA-TOXIN | TOBACCO CHLOROPLASTS | POLYPROTEIN VACCINE | Recombinant Fusion Proteins - immunology | Tuberculosis Vaccines - metabolism | Antigens, Bacterial - immunology | Bacterial Proteins - chemistry | Antigens, Bacterial - biosynthesis | Antigens, Bacterial - genetics | Chloroplasts | Bacterial Proteins - immunology | Tuberculosis Vaccines - immunology | Lettuce - metabolism | Tuberculosis Vaccines - genetics | Recombinant Fusion Proteins - biosynthesis | Gene Expression | Lettuce - chemistry | Lettuce - genetics | Antigens, Bacterial - chemistry | Plants, Genetically Modified - genetics | Administration, Oral | Plants, Genetically Modified - chemistry | Plants, Genetically Modified - immunology | Bacterial Proteins - genetics | Recombinant Fusion Proteins - chemistry | Animals | Plants, Genetically Modified - metabolism | Tuberculosis Vaccines - chemistry | Recombinant Fusion Proteins - genetics | Sheep | Bacterial Proteins - biosynthesis | Lettuce - immunology | Mycobacterium tuberculosis - genetics | Proteins | Antigens | Tuberculosis vaccines | Tuberculosis | Analysis | Genomics | Development and progression | Cholera toxin | Protein binding | Water-borne diseases | Temperature | Drug delivery systems | Erythrocytes | Infections | Genomes | Vaccines | Leaves | Red blood cells | E coli | Plant tissues | Protein folding | Low cost | Fusion protein | Public health | Freeze-drying | Hemolysis | Plants (botany) | Disulfide bonds | Bacterial infections | Toxin b | Cell walls | Blood cells | Stability analysis | Medicine | Tobacco | Infectious diseases | ESAT-6 antigen | Cholera | Index Medicus
Journal Article