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Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 36, pp. 26391 - 26399
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 2019, Volume 131, pp. 144 - 153
.... Allicin induces apoptosis or necrosis in a dose-dependent manner but biocompatible doses influence cellular metabolism and signalling cascades... 
T-cells | Cysteine | Allicin | IL-2 | S-thioallylation | Zinc | Protein modification | Actin | Glycolysis | Fibroblasts | Cytoskeleton | Interleukin IL-1 | Jurkat | Enolase | Warburg effect | APOPTOSIS | PHOSPHORYLATION | INHIBITION | ANTIBACTERIAL PRINCIPLE | ENDOCRINOLOGY & METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEMBRANES | FILAMENTS | ADF/COFILIN | CELL | Proteome - genetics | Actin Depolymerizing Factors - genetics | Membrane Glycoproteins - metabolism | Zinc - metabolism | Humans | Actins - metabolism | Sulfinic Acids - pharmacology | Garlic - chemistry | Tubulin - genetics | Actins - genetics | Actin Depolymerizing Factors - metabolism | Sulfhydryl Compounds - metabolism | Tubulin - metabolism | Sulfinic Acids - isolation & purification | Eukaryotic Initiation Factor-2 - metabolism | HSP90 Heat-Shock Proteins - genetics | Microfilament Proteins - metabolism | Filamins - genetics | Fructose-Bisphosphate Aldolase - metabolism | Microfilament Proteins - genetics | Fibroblasts - metabolism | Cell Line | Pyruvate Kinase - metabolism | Jurkat Cells | Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - genetics | Membrane Glycoproteins - genetics | HSP110 Heat-Shock Proteins - genetics | Filamins - metabolism | Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - metabolism | Animals | Eukaryotic Initiation Factor-2 - genetics | Fibroblasts - drug effects | HSP90 Heat-Shock Proteins - metabolism | Fibroblasts - cytology | Mice | Protein Processing, Post-Translational | Fructose-Bisphosphate Aldolase - genetics | HSP110 Heat-Shock Proteins - metabolism | Proteome - metabolism | Pyruvate Kinase - genetics
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 10, p. e0186615
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal disease. Histone deacetylase 6 (HDAC6) alters function and fate of various... 
EPITHELIAL-MESENCHYMAL TRANSITION | LUNG FIBROSIS | IN-VITRO | TGF-BETA | HISTONE DEACETYLASE INHIBITION | MULTIDISCIPLINARY SCIENCES | TUBULIN ACETYLATION | DISEASE | AUTOPHAGY | MYOFIBROBLAST DIFFERENTIATION | EXPRESSION | Idiopathic Pulmonary Fibrosis - genetics | Ribosomal Protein S6 Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Phosphoprotein Phosphatases - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Autophagy - drug effects | Idiopathic Pulmonary Fibrosis - metabolism | Mechanistic Target of Rapamycin Complex 1 | Autophagosomes - drug effects | Multiprotein Complexes - metabolism | Tubulin - metabolism | Bleomycin | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Aged, 80 and over | Female | Indoles - pharmacology | Lung - metabolism | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Hydroxamic Acids - pharmacology | Fibroblasts - metabolism | Lung - pathology | Collagen Type I - metabolism | Histone Deacetylases - genetics | Histone Deacetylase 6 | RNA, Messenger - genetics | Histone Deacetylases - metabolism | Nuclear Proteins - metabolism | Autophagosomes - metabolism | Mice, Knockout | Transforming Growth Factor beta - pharmacology | Animals | Signal Transduction - drug effects | Fibroblasts - drug effects | Idiopathic Pulmonary Fibrosis - pathology | Hydroxamic Acids - therapeutic use | Indoles - therapeutic use | Aged | Transforming Growth Factor beta - metabolism | Idiopathic Pulmonary Fibrosis - drug therapy | Histone deacetylase | Deregulation | Collagen (type I) | Phosphorylation | Disease | Mesenchyme | Pathogenesis | Critical care | AKT protein | Leucine | Kinases | Autophagy | Proteins | Fibroblasts | Vascular endothelial growth factor | Internal medicine | Lung diseases | Environmental health | 1-Phosphatidylinositol 3-kinase | Medicine | Pulmonary fibrosis | Inhibitors | Lungs | Lysine | Deacetylation | Collagen | Fibrosis | Mice | Protein phosphatase | Phagocytosis
Journal Article
Neuron, ISSN 0896-6273, 2003, Volume 40, Issue 3, pp. 485 - 499
The CNS is thought to develop from self-renewing stem cells that generate neurons, astrocytes, and oligodendrocytes. Other data, however, have suggested that... 
OLIGODENDROCYTE LINEAGE | PROGENITOR CELLS | TRANSCRIPTION FACTORS | GLIAL-RESTRICTED PRECURSORS | RAT CEREBRAL-CORTEX | SONIC HEDGEHOG | EMBRYONIC SPINAL-CORD | NEURAL-TUBE | CENTRAL-NERVOUS-SYSTEM | MAMMALIAN FOREBRAIN | NEUROSCIENCES | Immunohistochemistry | Green Fluorescent Proteins | O Antigens - metabolism | Embryo, Mammalian | Cell Count | Homeodomain Proteins - metabolism | Fibroblast Growth Factor 2 - pharmacology | Glial Fibrillary Acidic Protein - metabolism | Hedgehog Proteins | RNA, Messenger - biosynthesis | Time Factors | SOXE Transcription Factors | Neurons - metabolism | Basic Helix-Loop-Helix Transcription Factors | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Enzyme Inhibitors - pharmacology | Proteoglycans - metabolism | Rats | Oligodendrocyte Transcription Factor 2 | Mice | Astrocytes - metabolism | Oligodendroglia - metabolism | Flow Cytometry - methods | Epithelial Cells - metabolism | Epithelial Cells - drug effects | PAX7 Transcription Factor | Carbocyanines - metabolism | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Tubulin - metabolism | Transfection | Reverse Transcriptase Polymerase Chain Reaction - methods | beta-Galactosidase - metabolism | Fibroblast Growth Factor 2 - physiology | Bromodeoxyuridine - metabolism | Spinal Cord - cytology | Cell Differentiation - physiology | High Mobility Group Proteins - metabolism | Cells, Cultured | Zebrafish Proteins | Antigens - metabolism | Body Patterning - physiology | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Spinal Cord - embryology | Blotting, Northern | Animals | Cell Aggregation | Stem Cells - physiology | Trans-Activators - metabolism | Epidermal Growth Factor - pharmacology | In Vitro Techniques | Luminescent Proteins - metabolism | Spinal cord | Scholarships & fellowships | Neurosciences | Rodents | Stem cells | Experiments | Neurogenesis
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2013, Volume 288, Issue 17, pp. 11920 - 11929
Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 14, Issue 11, pp. 2653 - 2667
Neuronal function is highly sensitive to changes in oxygen levels, but how hypoxia affects dendritic spine formation and synaptogenesis is unknown. Here we... 
NEURONAL MIGRATION | MORPHOGENESIS | DOMAIN | PROTEIN | ACTIN | PROLYL HYDROXYLATION | PHOSPHORYLATION | RAT-BRAIN | HIF-ALPHA | REGULATES FILAMIN | CELL BIOLOGY | Rats, Wistar | Humans | Dendritic Spines - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors | Amino Acids, Dicarboxylic - pharmacology | Oxygen - metabolism | Cell Hypoxia | Tubulin - metabolism | Synapses - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | HEK293 Cells | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Filamins - genetics | Von Hippel-Lindau Tumor Suppressor Protein - antagonists & inhibitors | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Cells, Cultured | Hypoxia-Inducible Factor-Proline Dioxygenases - genetics | Filamins - antagonists & inhibitors | Rats | Hippocampus - cytology | Mice, Knockout | Up-Regulation - drug effects | Hippocampus - metabolism | Filamins - metabolism | Animals | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Cell Line, Tumor | Mice | Up-Regulation/drug effects | Hippocampus/cytology | Hypoxia-Inducible Factor-Proline Dioxygenases/antagonists & inhibitors | Tubulin/metabolism | Dendritic Spines/metabolism | Hypoxia-Inducible Factor 1, alpha Subunit/genetics | Oxygen/metabolism | Synapses/metabolism | Von Hippel-Lindau Tumor Suppressor Protein/antagonists & inhibitors | Life Sciences | Filamins/genetics | Hypoxia-Inducible Factor-Proline Dioxygenases/genetics | Filamins/metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases/metabolism | Von Hippel-Lindau Tumor Suppressor Protein/metabolism | Amino Acids, Dicarboxylic/pharmacology | Von Hippel-Lindau Tumor Suppressor Protein/genetics | Hippocampus/metabolism | Filamins/antagonists & inhibitors | Hypoxia-Inducible Factor 1, alpha Subunit/metabolism
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 476, Issue 7359, pp. 228 - 231
Journal Article
The Journal of neuroscience, ISSN 1529-2401, 2012, Volume 32, Issue 32, pp. 11095 - 11108
Journal Article
Cell death & disease, ISSN 2041-4889, 2018, Volume 9, Issue 10, pp. 990 - 17
Journal Article
Brain, ISSN 0006-8950, 09/2017, Volume 140, Issue 9, pp. 2460 - 2474
Journal Article