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European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2015, Volume 92, pp. 501 - 513
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2010, Volume 53, Issue 10, pp. 4248 - 4258
A series of 1-aryl-5-(3′,4′,5′-trimethoxyphenyl) derivatives and their related 1-(3′,4′,5′-trimethoxyphenyl)-5-aryl-1,2,4-triazoles, designed as cis-restricted... 
MEDICINAL CHEMISTRY | CYTOCHROME-C | IN-VITRO | CHEMISTRY, MEDICINAL | COLCHICINE SITE | CANCER CELLS | A-4 ANALOGS | TUBULIN POLYMERIZATION | MICROTUBULE DYNAMICS | A4 PHOSPHATE | CELL-DEATH | Reactive Oxygen Species - metabolism | Triazoles - chemistry | Tubulin Modulators - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Caspase 3 - metabolism | Structure-Activity Relationship | Membrane Potential, Mitochondrial - drug effects | Bibenzyls - chemistry | G2 Phase - drug effects | Tubulin Modulators - chemical synthesis | Cell Shape | Triazoles - chemical synthesis | Antineoplastic Agents - pharmacology | Tubulin - chemistry | Angiogenesis Inhibitors - chemical synthesis | Colchicine - chemistry | Endothelial Cells - physiology | Tubulin Modulators - chemistry | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Models, Molecular | Mitochondria - drug effects | Antineoplastic Agents - chemistry | Chick Embryo | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Bibenzyls - chemical synthesis | Triazoles - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Animals | Endothelial Cells - cytology | Cell Line, Tumor | Protein Binding | Bibenzyls - pharmacology | Enzyme Activation | Mitochondria - physiology | Angiogenesis Inhibitors - chemistry | Apoptosis | Drug Screening Assays, Antitumor | Endothelial Cells - drug effects
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 07/2017, Volume 134, pp. 110 - 118
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2017, Volume 127, pp. 1025 - 1034
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2014, Volume 57, Issue 15, pp. 6795 - 6808
A new class of compounds that incorporated the structural motif of the 1-(3′,4′,5′-trimethoxtbenzoyl)-3-arylamino-5-amino-1,2,4-triazole molecular skeleton was... 
IN-VITRO | POTENT | CHEMISTRY, MEDICINAL | MICROTUBULE STRUCTURE | TUBULIN POLYMERIZATION INHIBITORS | ANTICANCER AGENTS | ENDOTHELIAL-CELLS | COMBRETASTATIN A-4 | BIOLOGICAL EVALUATION | ANTITUMOR-ACTIVITY | CANCER | Neoplasm Transplantation | Apoptosis - drug effects | Stereoisomerism | Triazoles - chemistry | Tubulin Modulators - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Drug Resistance, Neoplasm | Structure-Activity Relationship | Tubulin Modulators - chemical synthesis | Carcinoma, Hepatocellular - drug therapy | Human Umbilical Vein Endothelial Cells - cytology | Triazines - chemistry | Triazoles - chemical synthesis | Antineoplastic Agents - pharmacology | Tubulin - chemistry | Angiogenesis Inhibitors - chemical synthesis | Colchicine - chemistry | Triazines - pharmacology | Tubulin Modulators - chemistry | Aniline Compounds - pharmacology | Human Umbilical Vein Endothelial Cells - drug effects | Liver Neoplasms - drug therapy | Angiogenesis Inhibitors - pharmacology | Models, Molecular | Antimitotic Agents - chemical synthesis | Neoplastic Stem Cells | Antineoplastic Agents - chemistry | Triazoles - pharmacology | Animals | Triazines - chemical synthesis | Protein Binding | Antimitotic Agents - pharmacology | Cell Proliferation - drug effects | Mice, Inbred BALB C | Aniline Compounds - chemistry | Cell Cycle - drug effects | Aniline Compounds - chemical synthesis | Angiogenesis Inhibitors - chemistry | Antimitotic Agents - chemistry | Drug Screening Assays, Antitumor
Journal Article