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Journal Article
British Journal of Haematology, ISSN 0007-1048, 01/2013, Volume 160, Issue 2, pp. 123 - 132
Summary Gamma delta (γδ) Τ cells are non‐conventional T lymphocyte effectors that can interact with and eradicate tumour cells. Several data demonstrate that... 
gamma delta T lymphocytes | cancer | immunotherapy | monoclonal antibodies | haematological oncology | Haematological oncology | Monoclonal antibodies | Immunotherapy | Gamma delta T lymphocytes | Cancer | T-Lymphocyte Subsets - immunology | Adjuvants, Immunologic - pharmacology | Dendritic Cells - immunology | Humans | Receptors, Antigen, T-Cell, alpha-beta - analysis | Cells, Cultured - transplantation | Receptors, Antigen, T-Cell, gamma-delta - genetics | Gene Rearrangement, delta-Chain T-Cell Antigen Receptor | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | Neoplasms - therapy | T-Lymphocytes, Cytotoxic - transplantation | T-Lymphocyte Subsets - chemistry | Diphosphonates - therapeutic use | Killer Cells, Natural - immunology | Cells, Cultured - immunology | Tumor Escape - immunology | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | Cells, Cultured - drug effects | Immunotherapy, Adoptive | Antigens, Neoplasm - immunology | Translational Medical Research | Clinical Trials as Topic | Immunity, Innate | T-Lymphocyte Subsets - transplantation | Immunologic Surveillance - immunology | Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor | T-Lymphocytes, Cytotoxic - chemistry | Receptors, Antigen, T-Cell, gamma-delta - analysis | Neoplasms - immunology | CD8-Positive T-Lymphocytes - immunology | Dendritic Cells - transplantation | Diphosphonates - pharmacology | Immunologic Surveillance | Tumor Escape | Killer Cells, Natural | Dendritic Cells | T-Lymphocytes, Cytotoxic | Neoplasms | CD8-Positive T-Lymphocytes | Life Sciences | Immunology | Mesenchymal Stromal Cells | Receptors, Antigen, T-Cell, alpha-beta | T-Lymphocytes, Regulatory | T-Lymphocyte Subsets | Antigens, Neoplasm | Adjuvants, Immunologic | Cells, Cultured | Diphosphonates | Receptors, Antigen, T-Cell, gamma-delta
Journal Article
Blood, ISSN 0006-4971, 04/2010, Volume 115, Issue 13, pp. 2695 - 2703
Viral infections and leukemic relapse account for the majority of treatment failures in patients with B-cell acute lymphoblastic leukemia (B-ALL) receiving... 
ALLOGENEIC TRANSPLANTATION | ADOPTIVE TRANSFER | IMMUNOTHERAPY | BONE-MARROW-TRANSPLANTATION | ACUTE LYMPHOBLASTIC-LEUKEMIA | RISK | ADENOVIRUS INFECTION | CYTOMEGALOVIRUS | HEMATOLOGY | 1ST COMPLETE REMISSION | CHEMOTHERAPY | Recombinant Fusion Proteins - immunology | T-Lymphocyte Subsets - immunology | Recurrence | T-Lymphocyte Subsets - cytology | Humans | Postoperative Complications - prevention & control | Cells, Cultured - transplantation | Neoplastic Stem Cells - immunology | Receptors, Antigen, T-Cell, alpha-beta - immunology | Adoptive Transfer | Coxsackie and Adenovirus Receptor-Like Membrane Protein | Receptors, Virus - genetics | Blood Cells - immunology | Feasibility Studies | Receptors, Virus - physiology | Postoperative Complications - virology | Single-Chain Antibodies - genetics | T-Lymphocytes, Cytotoxic - transplantation | Adult | Adenoviridae - immunology | Cells, Cultured - immunology | Antigens, CD19 - immunology | Recombinant Fusion Proteins - biosynthesis | T-Lymphocytes, Cytotoxic - immunology | Virus Diseases - immunology | Leukemia, B-Cell - pathology | Fetal Blood - cytology | T-Lymphocyte Subsets - transplantation | Antigens, Viral - immunology | Cytomegalovirus - immunology | Cell Line, Tumor - immunology | In Vitro Techniques | Leukemia, B-Cell - immunology | T-Lymphocytes, Cytotoxic - cytology | Cell Line, Transformed | Interferon-gamma - biosynthesis | Single-Chain Antibodies - immunology | Virus Diseases - prevention & control | Transplantation
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 24, pp. 6206 - 6214
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 10/2011, Volume 8, Issue 5, pp. 1480 - 1487
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2003, Volume 170, Issue 12, pp. 6338 - 6347
CD8(+) CTL play important roles against malignancy in both active and passive immunotherapy. Nonetheless, the success of antitumor CTL responses may be... 
INDUCED EXPRESSION | CARCINOMA-CELLS | HUMAN CARCINOEMBRYONIC ANTIGEN | CEA TRANSGENIC MICE | CYTOTOXIC LYMPHOCYTES | IMMUNE-RESPONSES | ENDOTHELIAL-CELLS | RECOMBINANT VACCINES | CANCER-IMMUNOTHERAPY | IMMUNOLOGY | IONIZING-RADIATION | Colonic Neoplasms - radiotherapy | Neoplasm Transplantation | Apoptosis - radiation effects | Humans | Up-Regulation - radiation effects | Tumor Cells, Cultured - transplantation | Antibodies, Blocking - pharmacology | fas Receptor - biosynthesis | Tumor Cells, Cultured - pathology | T-Lymphocytes, Cytotoxic - transplantation | Time Factors | Cell Division - immunology | Colonic Neoplasms - immunology | Intercellular Adhesion Molecule-1 - radiation effects | Intercellular Adhesion Molecule-1 - biosynthesis | Female | Tumor Cells, Cultured - radiation effects | fas Receptor - physiology | Epitopes, T-Lymphocyte - immunology | Membrane Glycoproteins - immunology | T-Lymphocytes, Cytotoxic - immunology | Immunotherapy, Adoptive - methods | T-Lymphocytes, Cytotoxic - radiation effects | Tumor Cells, Cultured - immunology | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Cell Division - radiation effects | Mice, Transgenic | Epitopes, T-Lymphocyte - radiation effects | Fas Ligand Protein | Animals | Apoptosis - immunology | Up-Regulation - immunology | Colonic Neoplasms - pathology | Ligands | Mice | fas Receptor - radiation effects | Cytotoxicity, Immunologic - radiation effects | Dose-Response Relationship, Radiation
Journal Article
Journal of Immunotherapy, ISSN 1524-9557, 06/2012, Volume 35, Issue 5, pp. 385 - 389
Malignant glioma is an incurable disease with a relatively short median survival. Several clinical trials have demonstrated that immunotherapy with vaccination... 
CTLA-4 | Vaccine | Glioma | GM-CSF | Immunotherapy | GVAX | ANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | COMBINATION IMMUNOTHERAPY | MECHANISMS | IMMUNOLOGY | BRAIN-TUMORS | RESPONSES | vaccine | GLIOBLASTOMA | ONCOLOGY | immunotherapy | GROWTH | glioma | CENTRAL-NERVOUS-SYSTEM | CLINICAL ACTIVITY | VACCINES | Gamma Rays | Neoplasm Transplantation | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Injections, Intraventricular | Tumor Cells, Cultured - transplantation | Antibodies, Monoclonal - therapeutic use | Brain Neoplasms - immunology | Glioma - therapy | Tumor Cells, Cultured - radiation effects | Brain Neoplasms - mortality | Antibodies, Monoclonal - immunology | Glioma - prevention & control | Glioma - mortality | Tumor Cells, Cultured - immunology | Mice, Inbred C57BL | Injections, Intraperitoneal | Glioma - immunology | Survival Rate | CTLA-4 Antigen - immunology | Brain Neoplasms - prevention & control | Cancer Vaccines - immunology | Animals | Antibodies, Monoclonal - administration & dosage | Interferon-gamma - immunology | Brain Neoplasms - therapy | T-Lymphocytes - immunology | Mice | CTLA-4 Antigen - antagonists & inhibitors | Interferon-gamma - biosynthesis | Animal models | Frontal lobe | Cell survival | Granulocyte-macrophage colony-stimulating factor | Immunosorbents | Brain tumors | Vaccination | Melanoma | Clinical trials | Cytotoxicity | Lymphocytes T | Immunity | Survival | Cancer vaccines | CTLA-4 protein | Splenocytes | Glioma cells | Monoclonal antibodies | Tumors
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3603 - 3617
Epithelial ovarian cancers (EOCs) often exhibit morphologic features of embryonic Mullerian duct-derived tissue lineages and colonize peritoneal surfaces that... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | TGF-BETA | HOMEOBOX GENE-EXPRESSION | BONE-MARROW-CELLS | MESENCHYMAL TRANSITION | HUMAN ENDOMETRIUM | STROMAL CELLS | SEX STEROIDS | TUMOR-GROWTH | Vascular Endothelial Growth Factor A - biosynthesis | Epithelial Cells - metabolism | Prognosis | Humans | Ovarian Neoplasms - pathology | Adipose Tissue - cytology | Carcinoma - mortality | Tumor Cells, Cultured - transplantation | Culture Media, Conditioned - pharmacology | Ovarian Neoplasms - mortality | Tumor Microenvironment - physiology | Vascular Endothelial Growth Factor A - genetics | Ovarian Neoplasms - genetics | Tumor Cells, Cultured - pathology | Chemokine CXCL12 - genetics | Peritoneum - cytology | Female | Gene Expression Regulation, Neoplastic - drug effects | Homeodomain Proteins - pharmacology | Carcinoma - pathology | Neoplasm Proteins - genetics | Carcinoma - secondary | Peritoneal Neoplasms - secondary | Tumor Microenvironment - drug effects | Mesenchymal Stromal Cells - drug effects | Interleukin-6 - genetics | Neoplasm Proteins - biosynthesis | Tumor Cells, Cultured - drug effects | Kaplan-Meier Estimate | Epithelial Cells - pathology | Transforming Growth Factor beta2 - physiology | Fibroblasts - pathology | Cell Division - drug effects | Transforming Growth Factor beta2 - biosynthesis | Animals | Cell Differentiation - drug effects | Endothelial Cells - cytology | Mice, Nude | Paracrine Communication - drug effects | Interleukin-6 - biosynthesis | Carcinoma - genetics | Chemokine CXCL12 - biosynthesis | Mice | Mesenchymal Stromal Cells - pathology | Transforming Growth Factor beta2 - genetics | Homeodomain Proteins - physiology | Endothelial Cells - drug effects | Fibroblasts | Physiological aspects | Genetic aspects | Research | Risk factors | Oncogenes | Ovarian cancer
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2017, Volume 140, Issue 5, pp. 1159 - 1172
PTPN11 mutation, a RAS signaling pathway mutation, is associated with MLL translocations in acute leukemia. A girl with MLL/AF10 AML was found to carry... 
M‐CSF | PTPN11 | cooperating leukemogenesis | monocytic leukemia | MLL/AF10 | M-CSF | SURVIVAL | CELLS | RAS | ACUTE MYELOID-LEUKEMIA | SOMATIC MUTATIONS | HETEROGENEITY | MUTANTS | ONCOLOGY | LEUKEMOGENESIS | INFANT | EXPRESSION | Leukemia, Monocytic, Acute - etiology | Cytarabine - therapeutic use | Coculture Techniques | Humans | Tumor Cells, Cultured - transplantation | Infant | Mutation, Missense | Interleukin-3 - pharmacology | Oncogene Proteins, Fusion - physiology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - physiology | Myeloid-Lymphoid Leukemia Protein - physiology | Cell Transformation, Neoplastic - genetics | Female | Leukemia, Myelomonocytic, Acute - etiology | Daunorubicin - therapeutic use | Leukemia, Myelomonocytic, Acute - genetics | Transduction, Genetic | Mice, Inbred C57BL | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Radiation Chimera | Macrophages - cytology | Leukemia, Monocytic, Acute - genetics | Disease Progression | Point Mutation | Drug Resistance, Neoplasm - genetics | Animals | Macrophage Colony-Stimulating Factor - blood | Cell Differentiation - drug effects | Myeloid-Lymphoid Leukemia Protein - genetics | Oncogene Proteins, Fusion - genetics | Bone Marrow - pathology | Mice | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics | Enzyme Activation - genetics | Anthracyclines | Chemotherapy | Analysis | Leukemia | Bone marrow | Genetic aspects | Transplantation | Macrophage colony stimulating factor | Cancer | Mutation | Cooperation
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