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Nature genetics, ISSN 1546-1718, 11/2016, Volume 49, Issue 1, pp. 10 - 16
There is a striking and unexplained male predominance across many cancer types. A subset of X-chromosome genes can escape X-inactivation, which would protect females from complete functional loss by a single mutation... 
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Chromosomes, Human, X - genetics | X Chromosome Inactivation - genetics | Neoplasms - genetics | Genes, X-Linked - genetics | Humans | Female | Male | Mutation - genetics | Genes, Tumor Suppressor | Sexism - statistics & numerical data | Tumor suppressor genes | Gene mutations | Analysis | Risk factors | Cancer | Hypotheses | Tobacco | Biology | Mutation | Males | Gene expression | Females | Chromosomes | Tumors | Index Medicus
Journal Article
Journal of thoracic oncology, ISSN 1556-0864, 06/2015, Volume 10, Issue 6, pp. 910 - 923
Epidermal growth factor receptor (EGFR) mutation status was reported to be associated with programmed death-ligand 1 (PD-L1) expression. However, the molecular... 
PD-L1 | NSCLC | PD-1 | EGFR | Tyrosine kinase inhibitors | Respiratory System | Oncology | Life Sciences & Biomedicine | Science & Technology | Tumor Escape - drug effects | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Sequence Deletion | Up-Regulation | Exons | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Molecular Targeted Therapy | Receptor, Epidermal Growth Factor - metabolism | T-Lymphocytes - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - immunology | Lung Neoplasms - enzymology | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Programmed Cell Death 1 Receptor - metabolism | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Carcinoma, Non-Small-Cell Lung - immunology | B7-H1 Antigen - metabolism | Lung Neoplasms - immunology | Apoptosis - immunology | B7-H1 Antigen - antagonists & inhibitors | Interferon-gamma - immunology | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | T-Lymphocytes - immunology | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Interferon-gamma - biosynthesis | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 03/2019, Volume 567, Issue 7749, pp. 479 - 485
The interplay between an evolving cancer and a dynamic immune microenvironment remains unclear. Here we analyse 258 regions from 88 early-stage, untreated... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Adenocarcinoma - pathology | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - pathology | Male | Female | Adenocarcinoma - genetics | Gene Expression Regulation, Neoplastic - genetics | Tumor Escape - immunology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - immunology | Antigen Presentation - immunology | Carcinoma, Squamous Cell - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Tumor Microenvironment - immunology | Disease-Free Survival | Lung Neoplasms - immunology | Evolution, Molecular | Lymphocytes, Tumor-Infiltrating - immunology | Causes of | Development and progression | Genetic aspects | Cellular immunity | Lung cancer | RNA sequencing | Epigenetic inheritance | Medical colleges | Histocompatibility antigens | RNA | Tumor antigens | HLA histocompatibility antigens | Lung cancer, Non-small cell | Tumors | Working groups | Brain cancer | Editing | Genomes | Metastases | Gene sequencing | Histopathology | Lymphocytes | Evolution | Bioinformatics | Immune system | Antigens | T cell receptors | Ribonucleic acid--RNA | Estimates | Heterozygosity | White blood cells | Pathology | Depletion | Loss of heterozygosity | Epigenetics | Biomarkers | Ligands | Infiltration | Microenvironments | Mutation | Cancer | Index Medicus
Journal Article
Molecular therapy, ISSN 1525-0016, 11/2013, Volume 21, Issue 11, pp. 2087 - 2101
Journal Article
Cancer discovery, ISSN 2159-8290, 09/2013, Volume 3, Issue 12, pp. 1355 - 1363
The success in lung cancer therapy with programmed death (PD)-1 blockade suggests that immune escape mechanisms contribute to lung tumor pathogenesis... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus
Journal Article