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2017, ISBN 9813147318, xii, 306 pages
Book
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2009, Volume 10, Issue 2, pp. 195 - 202
The neuronal guidance molecule netrin-1 is linked to the coordination of inflammatory responses. Given that mucosal surfaces are particularly prone to... 
ISCHEMIA-REPERFUSION INJURY | ECTO-5'-NUCLEOTIDASE CD73 | ADENOSINE A2B RECEPTOR | INDUCED VASCULAR LEAK | NUCLEOTIDE PHOSPHOHYDROLYSIS | HIF-1-DEPENDENT REPRESSION | AXON GUIDANCE | FACTOR-I | IMMUNOLOGY | KAPPA-B ACTIVITY | EXTRACELLULAR ADENOSINE | Immunohistochemistry | Immunoprecipitation | Netrin-1 | Humans | Immunoblotting | Nerve Growth Factors - metabolism | Hypoxia - metabolism | Inflammation - metabolism | Flow Cytometry | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Tumor Suppressor Proteins - genetics | Receptors, Purinergic P1 - immunology | Neutrophil Infiltration - immunology | Caco-2 Cells | Hypoxia-Inducible Factor 1, alpha Subunit - immunology | Gene Expression | Tumor Suppressor Proteins - metabolism | Enzyme-Linked Immunosorbent Assay | Receptors, Purinergic P1 - genetics | Gene Expression Regulation - immunology | Hypoxia - complications | Hypoxia - immunology | Inflammation - immunology | Nerve Growth Factors - immunology | Reverse Transcriptase Polymerase Chain Reaction | Tumor Suppressor Proteins - immunology | Mucous Membrane - metabolism | Animals | Mucous Membrane - immunology | Nerve Growth Factors - genetics | Fluorescent Antibody Technique | Inflammation - genetics | Mice | Receptors, Purinergic P1 - metabolism | Chemotaxis, Leukocyte - immunology | Complications and side effects | Physiological aspects | Hypoxia | Genetic aspects | Inflammation | Research | DNA binding proteins | Risk factors | Index Medicus
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 02/2015, Volume 91, Issue 2, pp. 351 - 359
Purpose Several individual clinical and preclinical studies have shown the possibility of evaluating tumor hypoxia by using noninvasive positron emission... 
Radiology | Hematology, Oncology and Palliative Medicine | LUNG-CANCER | HEAD | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | CHEMORADIOTHERAPY | BIODISTRIBUTION | F-18-FLUOROMISONIDAZOLE | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NECK-CANCER | REPRODUCIBILITY | RADIATION-THERAPY | Reproducibility of Results | Radiopharmaceuticals - pharmacokinetics | Rhabdomyosarcoma - metabolism | Rats | Rhabdomyosarcoma - pathology | Misonidazole - pharmacokinetics | Imidazoles - pharmacokinetics | Misonidazole - analogs & derivatives | Positron-Emission Tomography - methods | Rhabdomyosarcoma - diagnostic imaging | Oxygen - metabolism | Cell Hypoxia | Animals | Models, Biological | Computer Simulation | Sensitivity and Specificity | Cell Line, Tumor | Triazoles - pharmacokinetics | Nitroimidazoles - pharmacokinetics | PET imaging | Tracers (Biology) | Comparative analysis | Developmental biology | Tumors | Index Medicus | NEOPLASMS | BIOMEDICAL RADIOGRAPHY | NICOTINAMIDE | SENSITIVITY | CORRELATIONS | COMPARATIVE EVALUATIONS | CAT SCANNING | OXYGEN | MODIFICATIONS | ANOXIA | INJECTION | POSITRON COMPUTED TOMOGRAPHY | RESPIRATION | UPTAKE | RADIOLOGY AND NUCLEAR MEDICINE | FLUORINE 18 | BLOOD | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
International Journal of Cancer, ISSN 0020-7136, 10/2012, Volume 131, Issue 8, pp. 1755 - 1767
Hypoxia is known to play important roles in the development and progression of tumors. We previously demonstrated that S100A4, a critical molecule for... 
ovarian carcinoma | hypoxia | S100A4 | hypomethylation | STEM-CELLS | INDUCIBLE FACTOR-I | TUMOR PROGRESSION | NUCLEAR EXPRESSION | CELL-LINES | DNA-METHYLATION | HUMAN PROSTATE-CANCER | ONCOLOGY | ALLELIC LOSS | TRANSCRIPTIONAL REGULATION | CALPONIN H1 | RNA, Small Interfering - genetics | Prognosis | Follow-Up Studies | Adenocarcinoma, Mucinous - pathology | S100 Calcium-Binding Protein A4 | Humans | Cystadenocarcinoma, Serous - metabolism | Endometrial Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Cystadenocarcinoma, Serous - genetics | Cystadenocarcinoma, Serous - pathology | Ovary - cytology | Immunoenzyme Techniques | Ovarian Neoplasms - genetics | DNA Methylation | S100 Proteins - genetics | Chromatin Immunoprecipitation | Endometrial Neoplasms - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Female | Ovarian Neoplasms - metabolism | Real-Time Polymerase Chain Reaction | Ovary - metabolism | Response Elements | Adenocarcinoma, Clear Cell - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Neoplasm Invasiveness | RNA, Messenger - genetics | S100 Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Animals | Mice, Nude | Adenocarcinoma, Mucinous - metabolism | Fluorescent Antibody Technique | Endometrial Neoplasms - pathology | Hypoxia - physiopathology | Adenocarcinoma, Clear Cell - pathology | Mice | Mice, Inbred BALB C | Adenocarcinoma, Mucinous - genetics | Adenocarcinoma, Clear Cell - genetics | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, pp. e25911 - e25911
Background: Preclinical imaging requires anaesthesia to reduce motion-related artefacts. For direct translational relevance, anaesthesia must not significantly... 
HYPERTHERMIA | POSITRON-EMISSION-TOMOGRAPHY | RADIOSENSITIZATION | NORMOBARIC OXYGEN | ISOFLURANE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | CARBOGEN | AGENTS | MICE | BLOOD-FLOW | Hypoxia - drug therapy | Tomography, Emission-Computed, Single-Photon | Positron-Emission Tomography | Copper Radioisotopes - pharmacokinetics | Radiation-Sensitizing Agents - pharmacokinetics | Muscles - pathology | Oxygen - metabolism | Hypoxia - metabolism | Tissue Distribution | Adenocarcinoma - metabolism | Fluorine Radioisotopes - pharmacokinetics | Mice, Inbred CBA | Anesthesia | Female | Muscles - metabolism | Radiopharmaceuticals - pharmacokinetics | Neoplasms, Experimental - diagnosis | Organometallic Compounds - pharmacokinetics | Misonidazole - pharmacokinetics | Hypoxia - diagnosis | Misonidazole - analogs & derivatives | Adenocarcinoma - drug therapy | Thiosemicarbazones - pharmacokinetics | Adenocarcinoma - diagnosis | Animals | Organotechnetium Compounds - pharmacokinetics | Muscles - drug effects | Mice | Neoplasms, Experimental - metabolism | Gases - analysis | Neoplasms, Experimental - drug therapy | Usage | Blood gases | SPECT imaging | Analysis | Central nervous system agents | Tumors | Nuclear medicine | Animal models | Laboratories | Oncology | Biology | Technetium isotopes | Quantitation | Gas analysis | Cancer therapies | Blood | Reduction | Imaging | Tomography | Artefacts | Medical research | Oxygen | Medical imaging | Positron emission | Xylazine | Anesthetics | Single photon emission computed tomography | Isoflurane | Carriers | Studies | Artifacts | Gases | Ketamine | Councils | Hypoxia | Breathing | Respiration | Index Medicus
Journal Article
Journal Article
BioMed Research International, ISSN 2314-6133, 2018, Volume 2018, pp. 4174232 - 9
Journal Article
BMC Cancer, ISSN 1471-2407, 03/2013, Volume 13, Issue 1, pp. 108 - 108
Journal Article
British Journal of Cancer, ISSN 0007-0920, 01/2011, Volume 104, Issue 1, pp. 166 - 174
  The underlying mechanisms involved in the activation of hypoxia-inducible factor-1 (HIF-1) in gastric cancer remain unclear. As nuclear factor-κB (NF-κB) as... 
hypoxia | NF-κB | HIF-1α | gastric cancer | angiogenesis | tumour growth
Journal Article