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1. Full Text Structural biology of the tumor suppressor p53
by Joerger, Andreas C and Fersht, Alan R
Annual review of biochemistry, ISSN 0066-4154, 2008, Volume 77, Issue 1, pp. 557 - 582
Intrinsic disorder | Oncogenic mutation | Drug design | Multidomain protein | Transcription factor | Neoplasms - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Humans | Molecular Sequence Data | Transcription Factors - metabolism | Tumor Suppressor Protein p53 - physiology | Genes, p53 | Animals | Cell Cycle | Genes, Dominant | Models, Biological | Drug Design | Protein Structure, Quaternary | Tumor Suppressor Protein p53 - chemistry | Mutation | Molecular mechanics | Tumor suppressor genes | Research | Gene expression | Analysis | Cell cycle | Proteins | Genomics | Apoptosis | Tumors | Cancer | Index Medicus
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2. Full Text Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53
by Martinez-Zapien, Denise and Ruiz, Francesc Xavier and Poirson, Juline and Mitschler, André and Ramirez, Juan and Forster, Anne and Cousido-Siah, Alexandra and Masson, Murielle and Pol, Scott Vande and Podjarny, Alberto and Travé, Gilles and Zanier, Katia
Nature (London), ISSN 0028-0836, 01/2016, Volume 529, Issue 7587, pp. 541 - 545
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oncogene Proteins, Viral - chemistry | Humans | Molecular Sequence Data | Crystallography, X-Ray | Tumor Suppressor Protein p53 - genetics | Proteolysis | Oncogene Proteins, Viral - genetics | Human papillomavirus 16 - chemistry | Binding Sites | Repressor Proteins - metabolism | Oncogene Proteins, Viral - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Repressor Proteins - chemistry | Human papillomavirus 16 - pathogenicity | Tumor Suppressor Protein p53 - metabolism | Models, Molecular | Repressor Proteins - genetics | Mutant Proteins - metabolism | Ubiquitin-Protein Ligases - chemistry | Human papillomavirus 16 - metabolism | Amino Acid Motifs | Models, Biological | Mutant Proteins - chemistry | Protein Binding | Tumor Suppressor Protein p53 - chemistry | Analysis | Distribution | Tumor proteins | Health aspects | Papillomavirus infections | DNA viruses | Cervical cancer | Proteins | Human papillomavirus | Peptides | Mutation | Deoxyribonucleic acid--DNA | Tumors | Crystal structure | Index Medicus | Cristallography | Chemical Sciences
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3. Full Text P53 mutations in cancer
by Muller, Patricia A. J and Vousden, Karen H
Nature cell biology, ISSN 1465-7392, 01/2013, Volume 15, Issue 1, pp. 2 - 8
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Transcription Factors - physiology | Tumor Suppressor Proteins - metabolism | Signal Transduction | Humans | Gene Expression Regulation, Neoplastic | Mutant Proteins - genetics | Tumor Suppressor Protein p53 - metabolism | Mutant Proteins - metabolism | Mutant Proteins - physiology | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Neoplasms - drug therapy | Transcription Factors - metabolism | Tumor Suppressor Protein p53 - physiology | Tumor Suppressor Proteins - physiology | Animals | Neoplasms - genetics | Protein Binding | Protein Processing, Post-Translational | Mutation | Genetic aspects | Research | Gene mutations | Tumor proteins | Health aspects | Cancer | Index Medicus
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4. Full Text P53, a translational regulator: Contribution to its tumour-suppressor activity
by Marcel, V and Catez, F and Diaz, J.-J
Oncogene, ISSN 0950-9232, 03/2015, Volume 34, Issue 44, pp. 5513 - 5523
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Neoplasms - genetics | Genes, Tumor Suppressor - physiology | Humans | RNA, Messenger - genetics | Carcinogenesis - genetics | Protein Biosynthesis - genetics | Tumor Suppressor Protein p53 - genetics | Protein biosynthesis | Research | Tumor proteins | Genetic translation | Analysis | Tumorigenesis | RNA polymerase | Rodents | Tumors | Translation | Animal models | p53 Protein | c-Myc protein | Myc protein | DNA-directed RNA polymerase | Proteins | Protein synthesis | PTEN protein | Index Medicus
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5. Full Text Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature
by Sánchez, Yolanda and Segura, Victor and Marín-Béjar, Oskar and Athie, Alejandro and Marchese, Francesco P and González, Jovanna and Bujanda, Luis and Guo, Shuling and Matheu, Ander and Huarte, Maite
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5812 - 5812
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Colorectal Neoplasms - genetics | HCT116 Cells | Humans | Gene Expression Regulation, Neoplastic | Tumor Suppressor Protein p53 - metabolism | RNA, Long Noncoding - genetics | Gene Regulatory Networks | Tumor Suppressor Protein p53 - genetics | Protein Binding | DNA Damage | Genes, Tumor Suppressor | RNA, Long Noncoding - metabolism | Colorectal Neoplasms - metabolism | Index Medicus
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6. Full Text Modes of p53 Regulation
by Kruse, Jan-Philipp and Gu, Wei
Cell (Cambridge), ISSN 0092-8674, 2009, Volume 137, Issue 4, pp. 609 - 622
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proto-Oncogene Proteins c-mdm2 - genetics | Animals | Humans | Gene Expression Regulation, Neoplastic | Tumor Suppressor Protein p53 - metabolism | Protein Processing, Post-Translational | Proto-Oncogene Proteins c-mdm2 - metabolism | Tumor Suppressor Protein p53 - genetics | Physiological aspects | Tumor proteins | Laws, regulations and rules | Analysis | Index Medicus
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7. Full Text A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53
by Bernal, Federico and Wade, Mark and Godes, Marina and Davis, Tina N and Whitehead, David G and Kung, Andrew L and Wahl, Geoffrey M and Walensky, Loren D
Cancer cell, ISSN 1535-6108, 2010, Volume 18, Issue 5, pp. 411 - 422
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Humans | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - chemistry | Nuclear Proteins - chemistry | Proto-Oncogene Proteins c-mdm2 - chemistry | Tumor Suppressor Protein p53 - physiology | Animals | Protein Engineering | Cell Line, Tumor | Mice, Inbred NOD | Mice | Tumor Suppressor Protein p53 - chemistry | Binding Sites | Proto-Oncogene Proteins c-mdm2 - metabolism | Ubiquitin | Tumor proteins | Gene expression | Ligases | Analysis | Index Medicus
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