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1. Full Text Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
by Fourcade, Julien and Sun, Zhaojun and Benallaoua, Mourad and Guillaume, Philippe and Luescher, Immanuel F and Sander, Cindy and Kirkwood, John M and Kuchroo, Vijay and Zarour, Hassane M
Journal of Experimental Medicine, ISSN 0022-1007, 09/2010, Volume 207, Issue 10, pp. 2175 - 2186
The paradoxical coexistence of spontaneous tumor antigen-specific immune responses with progressive disease in cancer patients furthers the need to dissect the... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | AUTOIMMUNE | TOLERANCE | DISEASE | CD4(+) | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | EXHAUSTION | Apoptosis Regulatory Proteins - biosynthesis | Antigens, CD - immunology | Up-Regulation | Apoptosis Regulatory Proteins - immunology | CD8-Positive T-Lymphocytes - pathology | Antigens, CD - biosynthesis | Antigens, Neoplasm - immunology | Humans | Membrane Proteins - immunology | Melanoma - pathology | Hepatitis A Virus Cellular Receptor 2 | Membrane Proteins - biosynthesis | Interleukin-2 - immunology | Melanoma - immunology | Interferon-gamma - immunology | Tumor Necrosis Factor-alpha - immunology | CD8-Positive T-Lymphocytes - metabolism | Programmed Cell Death 1 Receptor | Epitopes, T-Lymphocyte - immunology | CD8-Positive T-Lymphocytes - immunology | Interleukin-2 - biosynthesis | Immunity, Cellular | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - biosynthesis | Index Medicus
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2. Cancer immunology, immunotherapy
: CII
Springer International (Firm)
Cancer immunology, immunotherapy, ISSN 1432-0851, 1982
Periodicals | Immunotherapy | Immunology
Journal
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3. Full Text NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
by Franchi, Luigi and Kamada, Nobuhiko and Nakamura, Yuumi and Burberry, Aaron and Kuffa, Peter and Suzuki, Shiho and Shaw, Michael H and Kim, Yun-Gi and Núñez, Gabriel
Nature Immunology, ISSN 1529-2908, 05/2012, Volume 13, Issue 5, pp. 449 - 456
Intestinal phagocytes transport oral antigens and promote immune tolerance, but their role in innate immune responses remains unclear. Here we found that... 
FLAGELLIN | PATTERN-RECOGNITION | NOD-LIKE RECEPTORS | ACTIVATES CASPASE-1 | MACROPHAGES | INTERLEUKIN-1-BETA | INFLAMMASOME RECEPTORS | INFECTION | NLRP3 INFLAMMASOME | SECRETION | IMMUNOLOGY | Inflammasomes - metabolism | Humans | Receptors, Interleukin-1 - genetics | Salmonella Infections - genetics | Salmonella Infections - immunology | Clonal Anergy | Caspase 1 - metabolism | Monocytes - metabolism | Monocytes - immunology | Intestines - immunology | Host-Pathogen Interactions - immunology | Signal Transduction - immunology | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Apoptosis Regulatory Proteins - genetics | Pseudomonas - immunology | Toll-Like Receptors - metabolism | Neutrophil Infiltration - immunology | Neutrophils - pathology | Apoptosis Regulatory Proteins - immunology | Flagellin - immunology | Receptors, Interleukin-1 - immunology | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Neutrophils - immunology | Salmonella - genetics | Signal Transduction - genetics | Phagocytes - immunology | Neutrophil Infiltration - genetics | Mice, Knockout | Pseudomonas Infections - immunology | Salmonella - immunology | Animals | Intestines - microbiology | Phagocytes - microbiology | Inflammasomes - immunology | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Calcium-Binding Proteins - genetics | Index Medicus
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4. Full Text Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
by Baitsch, Lukas and Baumgaertner, Petra and Devêvre, Estelle and Raghav, Sunil K and Legat, Amandine and Barba, Leticia and Wieckowski, Sébastien and Bouzourene, Hanifa and Deplancke, Bart and Romero, Pedro and Rufer, Nathalie and Speiser, Daniel E
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2350 - 2360
In chronic viral infections, CD8(+) T cells become functionally deficient and display multiple molecular alterations. In contrast, only little is known of... 
MEDICINE, RESEARCH & EXPERIMENTAL | MOLECULAR SIGNATURE | RESPONSES | VIRUS-INFECTION | PERSISTENCE | TOLERANCE | EFFECTOR FUNCTION | VACCINATION | EXPRESSION PROFILES | CHRONIC VIRAL-INFECTION | PD-1 | T-Lymphocyte Subsets - immunology | CD8-Positive T-Lymphocytes - pathology | Humans | Vaccination | Molecular Sequence Data | Cytomegalovirus Infections - immunology | Gene Expression Profiling | Cancer Vaccines - therapeutic use | Receptors, Immunologic - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | MART-1 Antigen - immunology | CpG Islands - immunology | Epstein-Barr Virus Infections - immunology | Herpesvirus 4, Human - immunology | Melanoma - secondary | Cancer Vaccines - immunology | Cytomegalovirus - immunology | T-Lymphocyte Subsets - pathology | Melanoma - immunology | T-Lymphocyte Subsets - metabolism | T-Cell Antigen Receptor Specificity | CD8-Positive T-Lymphocytes - immunology | Melanoma - therapy | Receptors, Immunologic - genetics | Virus Latency - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus | Abridged Index Medicus
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5. Cancer immunology and immunotherapy
Cancer immunology and immunotherapy, ISSN 0340-7004, 1976
immunology | Immunotherapy | therapy | Neoplasms | Cancer | Tumors
Journal
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6. Cellular and molecular immunology
by Lichtman, Andrew H and Abbas, Abul K and Elsevier Science (USA)
2003, 5th., ISBN 0721600085, 562
Antigens | Cellular immunity | Immunology | Molecular immunology | Lymphocytes
Book
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7. Full Text Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation
by Farache, Julia and Koren, Idan and Milo, Idan and Gurevich, Irina and Kim, Ki-Wook and Zigmond, Ehud and Furtado, Glaucia C and Lira, Sergio A and Shakhar, Guy
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 581 - 595
CD103 dendritic cells (DCs) carry bacteria from the small intestine and can present antigens to T cells. Yet they have not been recorded sampling luminal... 
TARGETED DISRUPTION | ENTERICA SEROVAR TYPHIMURIUM | IN-VIVO | RETINOIC-ACID | LYMPH-NODES | SALMONELLA-TYPHIMURIUM | TIGHT JUNCTION PROTEINS | LY6C(HI) MONOCYTES | IMMUNOLOGY | LAMINA PROPRIA | T-CELLS | Antigens, CD - immunology | Intestinal Mucosa - metabolism | Dendritic Cells - immunology | Antigens, Bacterial - immunology | CD11c Antigen - immunology | Antigens, CD - metabolism | Host-Pathogen Interactions - immunology | CD11c Antigen - metabolism | Cell Movement - immunology | Lymphocyte Activation - immunology | CD11c Antigen - genetics | Flow Cytometry | Intestinal Mucosa - immunology | Integrin alpha Chains - immunology | Salmonella typhi - physiology | CD8-Positive T-Lymphocytes - metabolism | Toll-Like Receptors - metabolism | Microscopy, Fluorescence, Multiphoton | Receptors, Chemokine - genetics | Dendritic Cells - metabolism | Salmonella typhimurium - physiology | Salmonella typhimurium - immunology | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Toll-Like Receptors - immunology | Cells, Cultured | Salmonella typhi - immunology | Integrin alpha Chains - metabolism | Intestinal Mucosa - microbiology | Receptors, Chemokine - immunology | Antigen Presentation - immunology | Mice, Knockout | Mucous Membrane - metabolism | Animals | Mucous Membrane - immunology | Cell Line, Tumor | Luminescent Proteins - genetics | Mice | CD8-Positive T-Lymphocytes - immunology | CX3C Chemokine Receptor 1 | Mucous Membrane - microbiology | Luminescent Proteins - metabolism | Flow cytometry | Motility | Microscopy | Morphology | Bone marrow | Bacteria | Behavior | Index Medicus
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8. Full Text Insulin inhibits IL-10-mediated regulatory T cell function: Implications for obesity
by Han, Jonathan M and Patterson, Scott J and Speck, Madeleine and Ehses, Jan A and Levings, Megan K
Journal of Immunology, ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 623 - 629
Chronic inflammation is known to promote metabolic dysregulation in obesity and type 2 diabetes. Although the precise origin of the unchecked inflammatory... 
IMMUNE-SYSTEM | INFLAMMATION | DISEASE | RESISTANCE | FAT | AKT | IMMUNOLOGY | DIET-INDUCED OBESITY | KEY PLAYERS | ADIPOSE-TISSUE | CUTTING EDGE | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Obesity - immunology | Insulin - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Macrophages - immunology | Hyperinsulinism - metabolism | Intra-Abdominal Fat - immunology | Transforming Growth Factor beta - immunology | Epithelium - metabolism | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Apyrase - immunology | CTLA-4 Antigen - metabolism | Inflammation - immunology | CTLA-4 Antigen - immunology | Intra-Abdominal Fat - metabolism | Obesity - metabolism | TOR Serine-Threonine Kinases - immunology | Insulin - metabolism | Macrophages - metabolism | Animals | Hyperinsulinism - immunology | Proto-Oncogene Proteins c-akt - immunology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Receptor, Insulin - metabolism | Mice | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
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9. Full Text VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics
by Lund, Amanda W and Duraes, Fernanda V and Hirosue, Sachiko and Raghavan, Vidya R and Nembrini, Chiara and Thomas, Susan N and Issa, Amine and Hugues, Stéphanie and Swartz, Melody A
Cell Reports, ISSN 2211-1247, 03/2012, Volume 1, Issue 3, pp. 191 - 199
Tumor expression of the lymphangiogenic factor VEGF-C is correlated with metastasis and poor prognosis, and although VEGF-C enhances transport to the draining... 
ACTIVATION | METASTASIS | DENDRITIC CELLS | GROWTH-FACTOR-C | SINUSOIDAL ENDOTHELIAL-CELLS | PERIPHERAL TOLERANCE | LYMPHANGIOGENESIS | INTERSTITIAL FLOW | INDUCTION | T-CELLS | CELL BIOLOGY | Lymph Nodes - pathology | Antigens, Neoplasm - immunology | Endothelial Cells - metabolism | Dendritic Cells - immunology | Peptides - immunology | Stromal Cells - metabolism | Histocompatibility Antigens Class I - immunology | Melanoma, Experimental - pathology | Lymph Nodes - immunology | Antigen Presentation - immunology | Cancer Vaccines - immunology | Melanoma, Experimental - prevention & control | Neoplasm Metastasis | Animals | Apoptosis - immunology | Melanoma, Experimental - immunology | Cross-Priming - immunology | Immune Tolerance - immunology | Vascular Endothelial Growth Factor C - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | Lymphangiogenesis | Index Medicus | Cell proliferation | Antigen presentation | Ovalbumin | Prognosis | CD8 antigen | Immunomodulation | Melanoma | Lymphocytes T | Immunological tolerance | Endothelial cells | Lymph nodes | Endothelium | Metastases | Antigen (tumor-associated) | Microenvironments | Apoptosis | Immune system | Tumors
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10. Tumor immunology
: methods and protocols
by Bondanza, Attilio and Casucci, Monica
2016, Methods in molecular biology, ISBN 1493933361, Volume 1393.
Immunological aspects | Immunotherapy | therapy | immunology | Neoplasms | Tumors
Web Resource
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11. Tumor immunology
: methods and protocols
by Bondanza, Attilio and Casucci, Monica
2016, Methods in molecular biology, ISBN 1493933361, Volume 1393.
Immunological aspects | Immunotherapy | therapy | immunology | Neoplasms | Tumors
Web Resource
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12. Full Text Autoantibody‐Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity
by Slight‐Webb, Samantha and Lu, Rufei and Ritterhouse, Lauren L and Munroe, Melissa E and Maecker, Holden T and Fathman, Charles G and Utz, Paul J and Merrill, Joan T and Guthridge, Joel M and James, Judith A
Arthritis & Rheumatology, ISSN 2326-5191, 10/2016, Volume 68, Issue 10, pp. 2492 - 2502
ObjectiveAntinuclear antibodies (ANAs) are detected in approximate to 18% of females, yet autoimmune disease develops in only 5-8%. Immunologic differences... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | INTERFERON | RISK-FACTORS | CYTOKINE PRODUCTION | DENDRITIC CELLS | ANTINUCLEAR ANTIBODIES | RHEUMATOLOGY | EXPRESSION | BLOOD MONONUCLEAR-CELLS | IG-LIKE RECEPTOR-1 | T-CELLS | Interferon-alpha - pharmacology | Multivariate Analysis | Phosphoproteins - drug effects | Interferon-beta - immunology | Antibodies, Antinuclear - immunology | Humans | Middle Aged | Interleukin-17 - immunology | STAT1 Transcription Factor - drug effects | Centromere Protein B - immunology | Male | Monocytes - immunology | Ribosomal Proteins - immunology | Healthy Volunteers | Case-Control Studies | Leukocytes - immunology | Young Adult | Flow Cytometry | Autoimmunity - immunology | Lupus Erythematosus, Systemic - immunology | Ribonucleoproteins - immunology | Tumor Necrosis Factor-alpha - immunology | Aged, 80 and over | Adult | B-Lymphocyte Subsets - immunology | Female | Interleukin-12 Subunit p40 - immunology | Cytokines - immunology | Interleukin 1 Receptor Antagonist Protein - immunology | Immunophenotyping | Logistic Models | Nuclear Proteins - immunology | STAT1 Transcription Factor - immunology | Stem Cell Factor - immunology | Interferon-alpha - immunology | Autoantibodies - immunology | Interferon-gamma - immunology | STAT3 Transcription Factor - drug effects | Sex Factors | Aged | Granulocyte Colony-Stimulating Factor - immunology | STAT3 Transcription Factor - immunology | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus | Systemic Lupus Erythematosus
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13. Full Text Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release
by Samstad, Eivind O and Niyonzima, Nathalie and Nymo, Stig and Aune, Marie H and Ryan, Liv and Bakke, Siril S and Lappegård, Knut T and Brekke, Ole-Lars and Lambris, John D and Damås, Jan K and Latz, Eicke and Mollnes, Tom E and Espevik, Terje
Journal of Immunology, ISSN 0022-1767, 03/2014, Volume 192, Issue 6, pp. 2837 - 2845
Inflammation is associated with development of atherosclerosis, and cholesterol crystals (CC) have long been recognized as a hallmark of atherosclerotic... 
ATHEROSCLEROTIC LESIONS | TUMOR-NECROSIS-FACTOR | C5A RECEPTOR | MEMBRANE ATTACK | STERILE INFLAMMATION | EPITHELIAL-CELLS | CARDIOVASCULAR EVENTS | INTERLEUKIN-1-BETA | OXIDATIVE BURST | ANAPHYLATOXINS | IMMUNOLOGY | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Complement C1q - immunology | Humans | Complement Pathway, Classical - drug effects | Complement C5a - metabolism | Complement System Proteins - immunology | Caspase 1 - metabolism | Monocytes - metabolism | Caspase 1 - immunology | Macrophage-1 Antigen - immunology | Monocytes - immunology | Interleukin-1beta - genetics | Complement Activation - immunology | Complement C1q - metabolism | Complement System Proteins - metabolism | Inflammasomes - drug effects | Reactive Oxygen Species - immunology | Complement C5 - immunology | Tumor Necrosis Factor-alpha - immunology | Macrophage-1 Antigen - metabolism | Complement Activation - drug effects | Cytokines - immunology | Interleukin-1beta - secretion | Complement C5 - metabolism | Tumor Necrosis Factor-alpha - secretion | Cells, Cultured | Cytokines - secretion | Phagocytosis - immunology | Interleukin-1beta - immunology | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Monocytes - drug effects | Complement Pathway, Classical - immunology | Microscopy, Confocal | Complement Pathway, Alternative - drug effects | Complement Pathway, Alternative - immunology | Inflammasomes - immunology | Cholesterol - pharmacology | Complement C5a - immunology | Index Medicus | Abridged Index Medicus
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14. Full Text Anti–Tumor Necrosis Factor-α Antibodies Induce Regulatory Macrophages in an Fc Region-Dependent Manner
by Vos, Anne Christine W and Wildenberg, Manon E and Duijvestein, Marjolijn and Verhaar, Auke P and van den Brink, Gijs R and Hommes, Daniel W
Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 1, pp. 221 - 230.e3
Background & Aims Anti–tumor necrosis factor (TNF)α antibodies are effective in treating patients with Crohn's disease whereas soluble TNFα receptors have not... 
Gastroenterology and Hepatology | Autoimmunity | IBD | Inflammatory Response | Type 2 Macrophage | MONOCLONAL-ANTIBODY | POLYMORPHISM | ACTIVE CROHNS-DISEASE | INFLAMMATORY-BOWEL-DISEASE | ACCENT-I | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | TNF-ALPHA | INFLIXIMAB | GASTROENTEROLOGY & HEPATOLOGY | T-LYMPHOCYTES | Cell Proliferation | Certolizumab Pegol | Humans | Lectins, C-Type - immunology | Anti-Inflammatory Agents - immunology | Caspase 3 - immunology | Antibodies, Monoclonal, Humanized | Lymphocyte Activation - immunology | Immunoglobulin Fc Fragments - immunology | Etanercept | Infliximab | Immunoglobulin G - immunology | T-Lymphocytes - drug effects | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | Immunoglobulin G - pharmacology | Immunosuppressive Agents - pharmacology | Antibodies, Monoclonal - immunology | Macrophages - immunology | Cytokines - immunology | Polyethylene Glycols - pharmacology | Leukocytes, Mononuclear - drug effects | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Cytokines - secretion | Crohn Disease - immunology | Receptors, Cell Surface - immunology | Immunoglobulin Fab Fragments - pharmacology | Mannose-Binding Lectins - immunology | Receptors, Fc - immunology | Immunosuppressive Agents - immunology | Lymphocyte Activation - drug effects | Caspase 3 - analysis | T-Lymphocytes - immunology | Immunoglobulin Fab Fragments - immunology | Adalimumab | Receptors, Tumor Necrosis Factor - immunology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Apoptosis | Index Medicus | Abridged Index Medicus
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