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Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1109 - 1123
Imatinib mesylate (IM), a potent inhibitor of the BCR/ABL tyrosine kinase, has become standard first-line therapy for patients with chronic myeloid leukemia... 
CHRONIC MYELOGENOUS LEUKEMIA | MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANT GLIOMA-CELLS | BLAST CRISIS | CLINICAL RESISTANCE | BCR-ABL MUTATIONS | ENDOPLASMIC-RETICULUM | CYTOCHROME-C RELEASE | CASPASE ACTIVATION | IMATINIB RESISTANCE | CHRONIC MYELOID-LEUKEMIA | Transcription Factor CHOP - genetics | Neoplastic Stem Cells - cytology | Gene Expression - drug effects | Calcium - metabolism | Gene Expression - genetics | Microtubule-Associated Proteins - metabolism | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Endoplasmic Reticulum - metabolism | Antineoplastic Agents - therapeutic use | Autophagy - physiology | Thiazoles - therapeutic use | Autophagy - drug effects | Chloroquine - pharmacology | Neoplastic Stem Cells - metabolism | RNA Interference | Endoplasmic Reticulum - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Macrolides - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Dasatinib | Chloroquine - therapeutic use | Piperazines - therapeutic use | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Mice, Inbred C3H | Xenograft Model Antitumor Assays | Fusion Proteins, bcr-abl - genetics | Animals | Cell Death - physiology | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Fusion Proteins, bcr-abl - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Benzamides | Macrolides - therapeutic use | Protein-Tyrosine Kinases - antagonists & inhibitors | Causes of | Physiological aspects | Genetic aspects | Chronic myeloid leukemia | Research | Drug therapy | Phagocytosis | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Colloid And Interface Science, ISSN 0021-9797, 03/2017, Volume 490, pp. 783 - 796
Chemotherapy is still the main adjuvant strategy after surgery in glioblastoma therapy. As the main obstacles of chemotherapeutic drugs for glioblastoma... 
Targeting drug delivery system | Aptamer | Paclitaxel-nanoconjugate | Nucleolin | Glioblastoma | DRUG-DELIVERY | CHEMISTRY, PHYSICAL | CONJUGATED NANOPARTICLES | CELL-SURFACE | PHASE-II | G-RICH OLIGONUCLEOTIDES | PACLITAXEL | MALIGNANT GLIOMA | CENTRAL-NERVOUS-SYSTEM | BRAIN GLIOMA | Human Umbilical Vein Endothelial Cells | Oligodeoxyribonucleotides - administration & dosage | Humans | Brain Neoplasms - pathology | Paclitaxel - pharmacokinetics | Aptamers, Nucleotide - administration & dosage | Drug Delivery Systems | Nanoconjugates - therapeutic use | Proteins - therapeutic use | Antineoplastic Agents, Phytogenic - administration & dosage | Proteins - administration & dosage | Antineoplastic Agents, Phytogenic - therapeutic use | Paclitaxel - administration & dosage | Antineoplastic Agents, Phytogenic - pharmacokinetics | Oligodeoxyribonucleotides - therapeutic use | Proteins - pharmacokinetics | Paclitaxel - analogs & derivatives | Aptamers, Nucleotide - therapeutic use | Brain Neoplasms - drug therapy | Nanoconjugates - administration & dosage | Paclitaxel - therapeutic use | Brain - drug effects | Animals | Mice, Nude | Glioblastoma - pathology | Oligodeoxyribonucleotides - pharmacokinetics | Brain - pathology | Cell Line, Tumor | Aptamers, Nucleotide - pharmacokinetics | Mice, Inbred BALB C | Glioblastoma - drug therapy | Antimitotic agents | Antineoplastic agents | Drugs | Chemotherapy | Drug delivery systems | Brain tumors | Smart drugs and nutrients | Glioblastoma multiforme | Vehicles | Cancer | Biomedical engineering | Glutamine | Index Medicus
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 03/2017, Volume 12, pp. 2117 - 2127
The blood-brain barrier is a formidable obstacle for glioma chemotherapy due to its compact structure and drug efflux ability. In this study, a dual-targeting... 
Biodegradable polymersomes | Angiopep-2 | Glioma treatment | Dual targeting | Doxorubicin | SOLID TUMORS | PENETRATION | NANOSCIENCE & NANOTECHNOLOGY | dual targeting | glioma treatment | BLOOD-BRAIN-BARRIER | CHEMOTHERAPY | ADJUVANT TEMOZOLOMIDE | GLIOBLASTOMA | PHARMACOLOGY & PHARMACY | biodegradable polymersomes | doxorubicin | RADIOTHERAPY | BLOCK-COPOLYMER | DENSITY-LIPOPROTEIN RECEPTOR | Rats, Wistar | Drug Carriers - administration & dosage | Male | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Drug Carriers - chemistry | Peptides - administration & dosage | Antibiotics, Antineoplastic - chemistry | Polyesters - administration & dosage | Antibiotics, Antineoplastic - pharmacokinetics | Doxorubicin - administration & dosage | Peptides - chemistry | Receptors, LDL - metabolism | Permeability | Blood-Brain Barrier - drug effects | Polyethylene Glycols - administration & dosage | Blood-Brain Barrier - metabolism | Antibiotics, Antineoplastic - administration & dosage | Polyesters - chemistry | Animals | Drug Carriers - pharmacokinetics | Cryoelectron Microscopy - methods | Drug Delivery Systems - methods | Glioma - drug therapy | Hydrogen-Ion Concentration | Drugs | Ethylene glycol | Usage | Drug delivery systems | Gliomas | Physiological aspects | Research | Drug therapy | Vehicles | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 539, Issue 7629, pp. 443 - 447
Journal Article
Journal Article
Journal Article
Small, ISSN 1613-6810, 01/2017, Volume 13, Issue 3, pp. np - n/a
Inflammation has been reported as one significant hallmark of breast cancer in relation to tumor development, metastasis, and invasion. The bradykinin receptor... 
dual stimuli responsive | drug delivery | ATP aptamer intercalation | breast cancer targeting | bradykinin receptor | CANCER-CELLS | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | FUNCTIONAL NUCLEIC-ACIDS | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | D-PEPTIDE LIGAND | NANOSCIENCE & NANOTECHNOLOGY | TUMOR-CELLS | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | KININ RECEPTORS | RNA LIGANDS | THERAPY | PROSTATE-CANCER | BRADYKININ B1 RECEPTOR | Doxorubicin - therapeutic use | Kallidin - therapeutic use | Nanoparticles - chemistry | Male | Drug Delivery Systems | Tissue Distribution | Endocytosis | Kallidin - analogs & derivatives | Female | Antineoplastic Agents - pharmacology | Nanoparticles - ultrastructure | Treatment Outcome | Rats, Sprague-Dawley | Doxorubicin - pharmacokinetics | Xenograft Model Antitumor Assays | Mammary Neoplasms, Animal - pathology | Animals | Tumor Burden - drug effects | Mice, Nude | Cell Line, Tumor | Drug Liberation | Polymers - chemistry | Mammary Neoplasms, Animal - drug therapy | Adenosine Triphosphate - chemistry | Doxorubicin - pharmacology | Hydrogen-Ion Concentration | Drugs | Chemotherapy | Anthracyclines | Drug delivery systems | Bradykinin | Metastasis | Drug therapy, Combination | Polymers | Vehicles | Cancer | Nanoparticles | Rodents | Breast cancer | Index Medicus | Conjugates | Receptors | Breast | Nanostructure | Tumors
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 32, Issue 18, pp. 4293 - 4305
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 2008, Volume 1784, Issue 1, pp. 159 - 185
Journal Article