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1. Full Text Lung cancers diagnosed at annual CT screening: Volume doubling times
by Henschke, Claudia I and Yankelevitz, David F and Yip, Rowena and Reeves, Anthony P and Farooqi, Ali and Xu, Dongming and Smith, James P and Libby, Daniel M and Pasmantier, Mark W and Miettinen, Olli S and I ELCAP Investigators and Writing Committee for the I-ELCAP Investigators
Radiology, ISSN 0033-8419, 2012, Volume 263, Issue 2, pp. 578 - 583
Purpose: To empirically address the distribution of the volume doubling time (VDT) of lung cancers diagnosed in repeat annual rounds of computed tomographic... 
SMALL PULMONARY NODULES | GUIDELINES 2ND EDITION | NATURAL-HISTORY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GROWTH-RATE | Reproducibility of Results | Humans | Tomography, X-Ray Computed - methods | Female | Lung Neoplasms - diagnostic imaging | Lung Neoplasms - pathology | Male | Tumor Burden | Chi-Square Distribution | Mass Screening - methods | Radiographic Image Interpretation, Computer-Assisted | Original Research
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2. Full Text Tumor Volume Doubling Time in Active Surveillance of Papillary Thyroid Carcinoma
by Oh, Hye-Seon and Kwon, Hyemi and Song, Eyun and Jeon, Min Ji and Kim, Tae Yong and Lee, Jeong Hyun and Kim, Won Bae and Shong, Young Kee and Chung, Ki-Wook and Baek, Jung Hwan and Kim, Won Gu
Thyroid, ISSN 1050-7256, 05/2019, Volume 29, Issue 5, pp. 642 - 649
Background: Tumor volume (TV) of papillary thyroid carcinoma (PTC) increases exponentially during active surveillance, and the growth rate differs for each... 
Thyroid Cancer and Nodules | ultrasonography | MICROCARCINOMA | tumor volume doubling time | METASTASES | ASSOCIATION GUIDELINES | CORE NEEDLE-BIOPSY | NATURAL-HISTORY | CANCER | NODULES | KOREAN SOCIETY | ENDOCRINOLOGY & METABOLISM | calcification | papillary thyroid carcinoma | CONSENSUS STATEMENT | active surveillance | PROGRESSION
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3. Full Text Tumour volume doubling time of molecular breast cancer subtypes assessed by serial breast ultrasound
by Ryu, Eun Bi and Chang, Jung Min and Seo, Mirinae and Kim, Sun Ah and Lim, Ji He and Moon, Woo Kyung
European Radiology, ISSN 0938-7994, 9/2014, Volume 24, Issue 9, pp. 2227 - 2235
The aim of our study was to evaluate the tumour volume doubling time (TVDT) of molecular breast cancer subtypes by serial ultrasound (US).Sixty-six patients... 
Molecular subtypes | Tumour volume doubling time | Medicine & Public Health | Diagnostic Radiology | Internal Medicine | Breast cancer | Interventional Radiology | Imaging / Radiology | Ultrasound | Neuroradiology | Triple-negative breast cancer | SURVIVAL | NEGATIVE TUMORS | PROGNOSIS | GROWTH-RATE | PATTERNS | ELASTOGRAPHY | MAMMOGRAPHY | WOMEN | IMPACT | BIOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Immunohistochemistry | Breast Neoplasms - surgery | Multivariate Analysis | Receptors, Estrogen - metabolism | Follow-Up Studies | Ultrasonography, Mammary - methods | Humans | Middle Aged | Receptor, ErbB-2 - metabolism | Tumor Burden | Disease Progression | Breast Neoplasms - metabolism | Time Factors | Biomarkers, Tumor - metabolism | Mastectomy | Adult | Female | Aged | Retrospective Studies | Breast Neoplasms - diagnostic imaging | Estrogen
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4. Full Text Tumor Volume Doubling Time as a Dynamic Prognostic Marker for Patients with Hepatocellular Carcinoma
by Kim, Jong Kwan and Kim, Hyung-Don and Jun, Mi-Jung and Yun, Sung-Cheol and Shim, Ju Hyun and Lee, Han Chu and Lee, Danbi and An, Jihyun and Lim, Young-Suk and Chung, Young-Hwa and Lee, Yung Sang and Kim, Kang Mo
Digestive Diseases and Sciences, ISSN 0163-2116, 10/2017, Volume 62, Issue 10, pp. 2923 - 2931
To evaluate the clinical value of tumor growth rate in hepatocellular carcinoma (HCC) patients, we investigated the growth rate of HCC by calculating the tumor... 
Biochemistry, general | Recurrence | Medicine & Public Health | Hepatology | Gastroenterology | Oncology | Hepatocellular carcinoma | Tumor doubling time | Survival | Transplant Surgery | CRITERIA | GROWTH-RATE | STAGING SYSTEMS | BCLC | TRANSARTERIAL CHEMOEMBOLIZATION | GASTROENTEROLOGY & HEPATOLOGY | STRATIFICATION | CLIP | Multivariate Analysis | Carcinoma, Hepatocellular - mortality | Cell Proliferation | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Liver Neoplasms - therapy | Liver Neoplasms - mortality | Carcinoma, Hepatocellular - diagnostic imaging | Time Factors | Female | Liver Neoplasms - pathology | Retrospective Studies | Chemoembolization, Therapeutic | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Proportional Hazards Models | Logistic Models | Treatment Outcome | Tumor Burden | Chi-Square Distribution | Liver Neoplasms - diagnostic imaging | Disease Progression | Disease-Free Survival | Magnetic Resonance Imaging | Carcinoma, Hepatocellular - pathology | Aged | Carcinoma, Hepatocellular - therapy | Medicine, Experimental | Medical research | Care and treatment | Prognosis | Hepatoma | Liver cancer | Medical imaging
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5. Full Text Cervical Tumor Volume Doubling Time: A Pilot Study
by Cosper, P and Olsen, J.R and Siegel, B and Dehdashti, F and Schwarz, J.K and Grigsby, P.W
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2015, Volume 93, Issue 3, pp. E258 - E259
Radiology | Hematology, Oncology and Palliative Medicine | Cervical cancer | Tumors
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6. Full Text Volume doubling time of lung cancer detected in idiopathic interstitial pneumonia: comparison with that in chronic obstructive pulmonary disease
by Kim, Cherry and Kim, Cherry and Lee, Sang Min and Lee, Sang Min and Choe, Jooae and Choe, Jooae and Chae, Eun Jin and Chae, Eun Jin and Do, Kyung-Hyun and Do, Kyung-Hyun and Seo, Joon Beom and Seo, Joon Beom
European Radiology, ISSN 0938-7994, 4/2018, Volume 28, Issue 4, pp. 1402 - 1409
To assess the volume doubling time (VDT) of lung cancers in IIP compared with COPD.A total of 61 patients (32 with IIP and 29 with COPD) were identified. A... 
Medicine & Public Health | Diagnostic Radiology | Idiopathic interstitial pneumonia | Lung cancer | Internal Medicine | Chronic obstructive pulmonary disease | Interventional Radiology | Imaging / Radiology | Ultrasound | Multislice computed tomography | Neuroradiology | Tumour volume | FIBROSIS | SMOKING | TRENDS | NODULES | NELSON | ASSOCIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | EPIDEMIOLOGY | AIR-FLOW OBSTRUCTION | TUMOR GROWTH | Pneumonia | Lung diseases, Obstructive | Squamous cell carcinoma | Pulmonary fibrosis | Bacterial pneumonia | Analysis | Diagnosis | Cancer | Adenocarcinoma | Segmentation | Small cell lung carcinoma | Lung diseases | Regression analysis | Multivariate analysis | Patients | Nodules | Obstructive lung disease | Health risk assessment | Tumors
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7. Full Text Prolongation of tumour volume doubling time (midDT) is associated with improvement in disease‐specific survival in patients with rapidly progressive radioactive iodine refractory differentiated thyroid cancer selected for molecular targeted therapy
by Sabra, Mona M and Sherman, Eric and Tuttle, Robert Michael
Clinical Endocrinology, ISSN 0300-0664, 04/2019, Volume 90, Issue 4, pp. 617 - 622
Summary Purpose To assess molecular targeted therapy (MTT)’s ability to affect tumour volume doubling time (TVDT) and disease‐specific survival (DSS) in... 
ENDOCRINOLOGY & METABOLISM | Care and treatment | Thyroid cancer | Patient outcomes | Oncology, Experimental | Metastasis | Research | Cancer | Lung diseases | Survival | Iodine | Tumors | Thyroid | Metastases
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8. Full Text Tumor volume doubling time of pulmonary metastases predicts overall survival and can guide the initiation of multikinase inhibitor therapy in patients with metastatic, follicular cell‐derived thyroid carcinoma
by Sabra, Mona M and Sherman, Eric J and Tuttle, R. Michael
Cancer, ISSN 0008-543X, 08/2017, Volume 123, Issue 15, pp. 2955 - 2964
BACKGROUND The current study was conducted to better characterize the association between overall survival (OS) from metastatic thyroid cancer and the rate of... 
lung metastasis | metastatic thyroid cancer | multikinase inhibitor (MKI) therapy | structural doubling time | overall survival (OS) | radioactive iodine‐refractory thyroid cancer | radioactive iodine-refractory thyroid cancer | PROGNOSTIC IMPACT | GROWTH-RATES | CANCER | CALCITONIN | ONCOLOGY | RECURRENCE | PAPILLARY | DISTANT METASTASES | Lung Neoplasms - drug therapy | Adenocarcinoma, Follicular - pathology | Thyroglobulin - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Lung Neoplasms - pathology | Male | Survival Rate | Tumor Burden | Young Adult | Lung Neoplasms - secondary | Protein Kinase Inhibitors - therapeutic use | Adenocarcinoma, Follicular - secondary | Adenocarcinoma, Follicular - drug therapy | Adolescent | Aged, 80 and over | Adult | Female | Adenocarcinoma, Follicular - metabolism | Aged | Retrospective Studies | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Cancer patients | Care and treatment | Thyroid cancer | Diagnosis | Research | Health aspects | Tumors | Correlation coefficient | Therapy | Growth rate | Lung cancer | Correlation coefficients | Metastasis | Patients | Survival | Metastases | Thyroid carcinoma | Inhibitors | Thyroglobulin | Mathematical analysis | Pulmonary lesions | Health risk assessment | Iodine | Cancer | Thyroid
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9. Full Text Correlation factors analysis of breast cancer tumor volume doubling time measured by 3D-ultrasound
by Zhang, Shuying and Ding, Yan and Zhu, Qiaoying and Wang, Cheng and Wu, Pengxi and Dong, Ji
Medical Science Monitor, ISSN 1234-1010, 06/2017, Volume 23, pp. 3147 - 3153
Background: Tumor volume doubling time (TVDT) is relatively important for breast cancer diagnosis and prognosis evaluation. This study aimed to analyze the... 
Tumor burden | Three-dimensional | Multivariate analysis | Imaging | MOLECULAR SUBTYPES | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | Multivariate Analysis | NEGATIVE TUMORS | BIOPSY | PATTERNS | PATHOLOGICAL FINDINGS | Tumor Burden | MAMMOGRAPHY | IMPACT | ULTRASOUND | OUTCOMES | Three-Dimensional | Humans | Middle Aged | Triple Negative Breast Neoplasms - diagnostic imaging | Linear Models | Factor Analysis, Statistical | Breast Neoplasms - pathology | Triple Negative Breast Neoplasms - pathology | Ultrasonography | Adult | Female | Aged | Breast Neoplasms - diagnostic imaging | Imaging, Three-Dimensional
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10. Full Text Effect of Tumor Volume Doubling Time on Prognosis for Stage I Non–small Cell Lung Cancers
by No, H and Gagne, H.M and Nelson, C.J and Kinsey, M and Garrison, G and Kikut, J and Gentchos, G and Seward, D and Sidiropoulos, N and Folefac, E and Leavitt, B and Ashikaga, T and Dragnev, K and Lin, S.H and Anker, C.J
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 10/2017, Volume 99, Issue 2, pp. E487 - E487
Medical colleges | Prognosis | Lung cancer, Non-small cell | Radiation | Tumors
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11. Full Text Epidermal Growth Factor Receptor Mutations: Effect on Volume Doubling Time of Non–Small-Cell Lung Cancer Patients
by Nakamura, Ryota and Inage, Yoshihisa and Tobita, Rika and Mori, Kazuko and Numata, Takeshi and Yanai, Hidetoshi and Endo, Takeo and Ohtani, Haruo and Satoh, Hiroaki and Yuzawa, Kenji and Koizumi, Masanori and Ueki, Hamaichi
Journal of Thoracic Oncology, ISSN 1556-0864, 09/2014, Volume 9, Issue 9, pp. 1340 - 1344
The purpose of this study was to retrospectively compare the volume doubling time (VDT) on serial computed tomography (CT) of non–small-cell lung cancer... 
Non–small-cell lung cancer | Epidermal growth factor receptor mutation | Volume doubling time | Non-small-cell lung cancer | GEFITINIB | APPEARANCE | ADENOCARCINOMA | SENSITIVITY | EGFR MUTATIONS | GENE MUTATION | TUMORS | FEATURES | NODULES | ONCOLOGY | RESPIRATORY SYSTEM | NELSON | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - genetics | Prognosis | Follow-Up Studies | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Lung Neoplasms - metabolism | Middle Aged | Carcinoma, Non-Small-Cell Lung - metabolism | Male | Tomography, X-Ray Computed | Carcinoma, Non-Small-Cell Lung - diagnosis | Disease Progression | Receptor, Epidermal Growth Factor - metabolism | Time Factors | DNA Mutational Analysis | Polymerase Chain Reaction | Aged, 80 and over | Female | Aged | Retrospective Studies | DNA, Neoplasm - genetics | Mutation | Lung Neoplasms - diagnosis
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12. Full Text Consequences of Referral Time and Volume Doubling Time in Inoperable Patients With Early Stage Lung Cancer
by Frelinghuysen, Michael and Fest, Jesse and Van der Voort Van Zyp, Noelle C and Van der Holt, Bronno and Hoogeman, Mischa and Nuyttens, Joost
Clinical Lung Cancer, ISSN 1525-7304, 2017, Volume 18, Issue 6, pp. e403 - e409
Micro-Abstract In 117 inoperable early stage lung cancer patients treated with stereotactic body radiotherapy, referral time (time between diagnostic and... 
Hematology, Oncology and Palliative Medicine | Pulmonary/Respiratory | Progression | Biology | Survival | Growth speed | SBRT | PULMONARY NODULES | GROWTH-RATE | TUMOR | FOLLOW-UP | RADIATION-THERAPY | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | STEREOTACTIC BODY RADIOTHERAPY | PROSPECTIVE PHASE-II | CARCINOMA | CLINICAL-OUTCOMES | Humans | Middle Aged | Lung Neoplasms - radiotherapy | Tomography, X-Ray Computed - methods | Lung Neoplasms - pathology | Male | Survival Rate | Referral and Consultation - statistics & numerical data | Tumor Burden | Disease Progression | Time Factors | Aged, 80 and over | Adult | Female | Lung Neoplasms - diagnostic imaging | Aged | Neoplasm Staging | Radiosurgery - methods
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13. Full Text The impact of histology and ground-glass opacity component on volume doubling time in primary lung cancer
by Obayashi, Kai and Shimizu, Kimihiro and Nakazawa, Seshiru and Nagashima, Toshiteru and Yajima, Toshiki and Kosaka, Takayuki and Atsumi, Jun and Kawatani, Natsuko and Yazawa, Tomohiro and Kaira, Kyoichi and Mogi, Akira and Kuwano, Hiroyuki
Journal of Thoracic Disease, ISSN 2072-1439, 09/2018, Volume 10, Issue 9, pp. 5428 - 5434
Background: Correlations between volume doubling time (VDT) of primary lung cancer (PLC), histology, and ground glass opacity (GGO) components remain unclear.... 
Adenocarcinoma | Volume doubling time (VDT) | Ground glass opacity (GGO) | Primary lung cancer (PLC) | SURVIVAL | ground glass opacity (GGO) | RESPIRATORY SYSTEM | adenocarcinoma | CLASSIFICATION | primary lung cancer (PLC) | TUMOR-GROWTH | Original
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14. Full Text Volume-doubling time of pulmonary nodules with ground glass opacity at multidetector CT. Assessment with computer-aided three-dimensional volumetry
by Oda, Seitaro and Awai, Kazuo and Murao, Kohei and Ozawa, Akio and Utsunomiya, Daisuke and Yanaga, Yumi and Kawanaka, Koichi and Yamashita, Yasuyuki
Academic Radiology, ISSN 1076-6332, 01/2011, Volume 18, Issue 1, pp. 63 - 69
Rationale and Objectives: To investigate the volume-doubling time (VDT) of histologically proved pulmonary nodules showing ground glass opacity (GGO) at... 
Multidetector CT | Ground glass opacity | Volume-doubling time | Volumetry | HISTOLOGIC CHARACTERISTICS | TOMOGRAPHY | volumetry | ADENOCARCINOMA | GROWTH-RATE | ground glass opacity | REPRODUCIBILITY | ACCURACY | multidetector CT | LUNG-CANCER | HELICAL CT | THIN-SECTION CT | AUTOMATED VOLUMETRY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Diagnosis, Differential | Lung - pathology | Follow-Up Studies | Humans | Middle Aged | Imaging, Three-Dimensional - methods | Tomography, Spiral Computed - methods | Lung Neoplasms - pathology | Male | Lung - diagnostic imaging | Tumor Burden | Carcinoma, Bronchogenic - diagnostic imaging | Carcinoma, Bronchogenic - pathology | Solitary Pulmonary Nodule - diagnostic imaging | Radiographic Image Interpretation, Computer-Assisted - methods | Hyperplasia - diagnostic imaging | Female | Lung Neoplasms - diagnostic imaging | Aged | Retrospective Studies | Adenocarcinoma - diagnostic imaging | Observer Variation | Solitary Pulmonary Nodule - pathology
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15. Full Text Correlation between ultrasonic tumor volume doubling time (TVDT) and malignant molecule expression in breast cancer
by Gen-Jin Wang and Da-Xue Yan
Journal of Hainan Medical University, ISSN 1007-1237, 08/2018, Volume 24, Issue 8, pp. 73 - 77
Objective: To investigate the correlation between ultrasonic tumor volume doubling time (TVDT) and malignant molecule expression in breast cancer. Methods: A... 
Breast cancer | Proliferation | Ultrasonic tumor volume doubling time | Invasion
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16. MIB-1 labeling index correlated with magnetic resonance imaging detected tumor volume doubling time in pituitary adenoma
by Hsu, Chih-Yi and Guo, Wan-Yuo and Chien, Chen-Ping and Ho, Donald Ming-Tak
European Journal of Endocrinology, ISSN 0804-4643, 06/2010, Volume 162, Issue 6, pp. 1027 - 1033
Objective: The purpose of this study was to evaluate whether MIB-1 labeling index (LI) could be used to predict growth velocity of residual pituitary adenomas... 
INVASIVENESS | RELEVANCE | GROWTH | ENDOCRINOLOGY & METABOLISM | KI-67 ANTIGEN | MONOCLONAL-ANTIBODY | RADIOTHERAPY | PROLIFERATION MARKERS | EXPRESSION | IMMUNOHISTOCHEMISTRY | P53 | Pituitary Neoplasms - surgery | Prognosis | Humans | Middle Aged | Male | Pituitary Neoplasms - pathology | Tumor Burden | Neoplasm Recurrence, Local - surgery | Neoplasm Recurrence, Local - pathology | Magnetic Resonance Imaging | Mitotic Index | Adult | Female
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17. Full Text A retrospective study of volume doubling time in surgically resected non‐small cell lung cancer
by Mackintosh, John A and Marshall, Henry M and Yang, Ian A and Bowman, Rayleen V and Fong, Kwun M
Respirology, ISSN 1323-7799, 07/2014, Volume 19, Issue 5, pp. 755 - 762
Background and objective Volume doubling time (VDT) contributes to the evaluation of the indeterminate pulmonary nodule, an increasingly frequent problem given... 
adenocarcinoma | lung neoplasm | tomography | non‐small cell lung cancer | time factor | non-small cell lung cancer | SMALL PULMONARY NODULES | MANAGEMENT | RESPIRATORY SYSTEM | GROWTH-RATE | FOLLOW-UP | CARCINOMA | FEATURES | Carcinoid Tumor - surgery | Adenocarcinoma - pathology | Cell Proliferation | Carcinoma, Large Cell - pathology | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Lung Neoplasms - pathology | Male | Tomography, X-Ray Computed | Carcinoma, Squamous Cell - diagnostic imaging | Positron-Emission Tomography | Pneumonectomy | Time Factors | Aged, 80 and over | Female | Retrospective Studies | Carcinoma, Non-Small-Cell Lung - pathology | Carcinoma, Non-Small-Cell Lung - surgery | Carcinoid Tumor - diagnostic imaging | Tumor Burden | Carcinoid Tumor - pathology | Carcinoma, Large Cell - surgery | Carcinoma, Large Cell - diagnostic imaging | Lung Neoplasms - diagnostic imaging | Lung Neoplasms - surgery | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Adenocarcinoma - diagnostic imaging | Adenocarcinoma - surgery | Cohort Studies | Squamous cell carcinoma | Analysis | Oncology, Experimental | Lung cancer, Small cell | Research | Lung cancer, Non-small cell | Cancer
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