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nuclear proteins - metabolism (649) 649
twist-related protein 1 - genetics (637) 637
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cell biology (301) 301
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transcription factors - metabolism (250) 250
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twist1 (197) 197
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cell movement (149) 149
developmental biology (146) 146
genetic aspects (144) 144
gene-expression (141) 141
article (140) 140
cells (137) 137
emt (133) 133
twist-related protein 1 (132) 132
tumors (130) 130
breast neoplasms - pathology (129) 129
breast cancer (128) 128
cell proliferation (126) 126
epithelial-mesenchymal transition - genetics (126) 126
analysis (122) 122
invasion (121) 121
apoptosis (116) 116
breast neoplasms - metabolism (116) 116
reverse transcriptase polymerase chain reaction (115) 115
twist-related protein 1 - biosynthesis (115) 115
cadherins - genetics (113) 113
progression (113) 113
gene expression regulation, developmental (110) 110
phenotype (107) 107
rna interference (107) 107
activation (106) 106
mice, nude (106) 106
neoplasm metastasis (106) 106
research article (104) 104
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snail (99) 99
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Nature, ISSN 0028-0836, 02/2010, Volume 463, Issue 7283, pp. 958 - 962
Heterozygous mutations in the gene encoding the CHD (chromodomain helicase DNA-binding domain) member CHD7, an ATP-dependent chromatin remodeller homologous to... 
NETWORK | COMPLEX | PROTEIN | CHROMATIN | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | TRANSCRIPTION | POLYMERASE-II | MUTATIONS | EXPRESSION | CHARGE-SYNDROME | Embryonic Stem Cells - metabolism | Embryo, Nonmammalian - cytology | Embryonic Stem Cells - cytology | Xenopus Proteins - genetics | Humans | Multipotent Stem Cells - metabolism | Embryo, Nonmammalian - metabolism | Embryo, Nonmammalian - embryology | DNA-Binding Proteins - deficiency | Neural Crest - metabolism | Xenopus Proteins - chemistry | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Developmental | Transcription, Genetic | Cell Differentiation | Xenopus laevis - genetics | DNA Helicases - genetics | Snail Family Transcription Factors | SOX9 Transcription Factor - metabolism | Cell Line | DNA Helicases - chemistry | Neural Crest - cytology | Xenopus laevis - embryology | Chromosomal Proteins, Non-Histone - metabolism | DNA Helicases - deficiency | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Syndrome | Chromosomal Proteins, Non-Histone - genetics | Transcription Factors - metabolism | Cell Lineage | DNA Helicases - metabolism | Animals | Xenopus Proteins - deficiency | Multipotent Stem Cells - cytology | Neural Crest - embryology | Xenopus laevis - metabolism | Twist-Related Protein 1 - genetics | Protein Binding | Xenopus Proteins - metabolism | Enhancer Elements, Genetic - genetics | Twist-Related Protein 1 - metabolism | SOX9 Transcription Factor - genetics | Cell Movement | Chromatin | Drosophila | Polybrominated biphenyls | Physiological aspects | Genetic aspects | Research | Structure | Embryonic stem cells | Helicases | Proteins | Labeling | Evacuations & rescues | Cell adhesion & migration | Human | Peripheral nervous system | Genes | Charge | Bones | Activation | Numerical control | Gene expression | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 9, pp. 864 - 875
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7579, pp. 525 - 530
Diagnosis of pancreatic ductal adenocarcinoma (PDAC) is associated with a dismal prognosis despite current best therapies; therefore new treatment strategies... 
STEM-CELLS | REPRESSION | DUCTAL ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | RESISTANCE | TUMOR-CELLS | PROLIFERATION | EMT | SNAIL | BETA | Adenocarcinoma - pathology | Pancreatic Neoplasms - metabolism | Transcription Factors - deficiency | Carcinoma, Pancreatic Ductal - metabolism | Deoxycytidine - pharmacology | Male | Nucleoside Transport Proteins - metabolism | Twist-Related Protein 1 - deficiency | Pancreatic Neoplasms - drug therapy | Deoxycytidine - therapeutic use | Adenocarcinoma - metabolism | Neoplasm Invasiveness - pathology | Epithelial-Mesenchymal Transition | Female | Snail Family Transcription Factors | Disease Models, Animal | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Transcription Factors - genetics | Adenocarcinoma - drug therapy | Carcinoma, Pancreatic Ductal - pathology | Disease Progression | Transcription Factors - metabolism | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Neoplasm Metastasis - pathology | Survival Analysis | Twist-Related Protein 1 - genetics | Cell Proliferation - drug effects | Mice | Twist-Related Protein 1 - metabolism | Deoxycytidine - analogs & derivatives | Drug Resistance, Neoplasm - drug effects | Care and treatment | Prognosis | Diagnosis | Pancreatic cancer | Analysis | Cancer cells | Studies | Cell growth | Chemotherapy | Transcription factors | Medical prognosis | Metastasis | Gene expression | Cancer therapies | Tumors | Apoptosis | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2008, Volume 14, Issue 1, pp. 79 - 89
Twist1 and Twist2 are major regulators of embryogenesis. Twist1 has been shown to favor the metastatic dissemination of cancer cells through its ability to... 
CELLBIO | HUMDISEASE | SIGNALING | BREAST-CANCER | TRANSFORMATION | DORSOVENTRAL PATTERN | ONCOGENIC RAS | ONCOLOGY | IN-VIVO | ZYGOTIC GENE | SUPPRESSION | EXPRESSION | TUMORIGENESIS | CELL IMMORTALIZATION | Neoplasms - metabolism | Up-Regulation | Fibroblasts - enzymology | Epithelial Cells - metabolism | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | Transplantation, Heterologous | Cell Transdifferentiation - genetics | Mammary Glands, Human - metabolism | Transfection | Neoplasms - genetics | RNA Interference | Cell Transformation, Neoplastic - genetics | Mice, Inbred DBA | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Fibroblasts - metabolism | Cell Line | Cellular Senescence - genetics | Neoplasm Invasiveness | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Neoplasms - enzymology | Repressor Proteins - genetics | Epithelial Cells - pathology | Mice, Transgenic | Nuclear Proteins - metabolism | Fibroblasts - pathology | Cell Transformation, Neoplastic - metabolism | Animals | Mice, Nude | Dogs | Epithelial Cells - enzymology | Twist-Related Protein 1 - genetics | Mice | Enzyme Activation | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | Twist-Related Protein 1 - metabolism | Tumor proteins | Stem cells | Tumors | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2017, Volume 19, Issue 5, pp. 518 - 529
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2015, Volume 17, Issue 5, pp. 678 - 688
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2010, Volume 285, Issue 47, pp. 36721 - 36735
Dysregulation of microRNAs is observed in many cancers, including breast cancer. In particular, miR-10b appears to play an important role in tumor cell... 
MIGRATION | CD44 INTERACTION | STRESS FIBERS | METASTASIS | CANCER CELLS | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | TYROSINE KINASES | HYALURONIC-ACID | FOCAL ADHESIONS | RNA, Small Interfering - genetics | Cell Proliferation | src-Family Kinases | Protein-Tyrosine Kinases - metabolism | Homeodomain Proteins - metabolism | Humans | MicroRNAs - metabolism | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Immunoenzyme Techniques | Breast Neoplasms - metabolism | Protein-Tyrosine Kinases - genetics | Chromatin Immunoprecipitation | rho-Associated Kinases - metabolism | Adjuvants, Immunologic - metabolism | Hyaluronan Receptors - metabolism | Female | Tumor Cells, Cultured | Nuclear Proteins - genetics | Twist-Related Protein 1 - antagonists & inhibitors | Neoplasm Invasiveness | rho GTP-Binding Proteins - genetics | RNA, Messenger - genetics | rho-Associated Kinases - genetics | Nuclear Proteins - metabolism | rhoC GTP-Binding Protein | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Hyaluronan Receptors - genetics | Blotting, Western | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Hyaluronic Acid - metabolism | Nuclear Proteins - antagonists & inhibitors | rho GTP-Binding Proteins - metabolism | Fluorescent Antibody Technique | Twist-Related Protein 1 - genetics | Cytoskeleton - metabolism | MicroRNAs - genetics | Twist-Related Protein 1 - metabolism | Apoptosis | Cell Movement | Index Medicus | Cytoskeleton | MicroRNA | Cell Surface Receptor | Signal Transduction | Hyaluronate | Breast Cancer
Journal Article
Cancer Cell, ISSN 1535-6108, 09/2013, Volume 24, Issue 3, pp. 347 - 364
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2010, Volume 12, Issue 10, pp. 982 - 992
Journal Article
Cancer Cell, ISSN 1535-6108, 02/2014, Volume 25, Issue 2, pp. 210 - 225
Twist is a key transcription activator of epithelial-mesenchymal transition (EMT). It remains unclear how Twist induces gene expression. Here we report a... 
TARGET | RECRUITMENT | NMR | INHIBITION | CHROMATIN | ONCOLOGY | DISEASE | SWITCH | LEUKEMIA | BROMODOMAIN | BINDING | CELL BIOLOGY | Transcription Factors - chemistry | Carcinoma, Basal Cell - genetics | Humans | Positive Transcriptional Elongation Factor B - metabolism | RNA Polymerase II - metabolism | Wnt-5a Protein | Wnt Proteins - metabolism | Promoter Regions, Genetic - genetics | Immunoenzyme Techniques | Histone Acetyltransferases - metabolism | Carcinoma, Basal Cell - prevention & control | Neoplastic Stem Cells - pathology | Female | Transcription, Genetic | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Acetylation | Tumor Cells, Cultured | Lysine Acetyltransferase 5 | Nuclear Proteins - genetics | Proto-Oncogene Proteins - metabolism | Twist-Related Protein 1 - antagonists & inhibitors | Neoplasm Invasiveness | Nuclear Proteins - metabolism | Carcinoma, Basal Cell - pathology | Transcription Factors - genetics | Mice, SCID | Nuclear Proteins - chemistry | Blotting, Western | Breast Neoplasms - prevention & control | Transcription Factors - metabolism | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Transformation, Neoplastic | Nuclear Proteins - antagonists & inhibitors | Fluorescent Antibody Technique | Mice, Inbred NOD | Mice | HeLa Cells | Twist-Related Protein 1 - metabolism | Gene expression | Medical colleges | Breast cancer | Index Medicus
Journal Article