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epithelial-mesenchymal transition (180) 180
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Cell Death and Differentiation, ISSN 1350-9047, 02/2011, Volume 18, Issue 2, pp. 271 - 281
Journal Article
Cancers, ISSN 2072-6694, 09/2019, Volume 11, Issue 9, p. 1392
Diffuse invasion into adjacent brain matter by glioblastoma (GBM) is largely responsible for their dismal prognosis. Previously, we showed that the TWIST1 (TW)... 
dimerization | TWIST1 | glioblastoma | invasion | periostin
Journal Article
Circulation, ISSN 0009-7322, 03/2015, Volume 131, Issue 11, pp. 1006 - 1018
BACKGROUND—The vascular remodeling responsible for pulmonary arterial hypertension (PAH) involves predominantly the accumulation of α-smooth muscle... 
Human | Hypertension | Vimentin | Sirolimus | Twist1 protein | Vascular remodeling | Epithelial-mesenchymal transition | Neointima | Animal | Type ii | Models | Bone morphogenetic protein receptors | Cardiovascular diseases | Pulmonary | RAPAMYCIN | MIGRATION | FIBROSIS | models, animal | CARDIAC & CARDIOVASCULAR SYSTEMS | neointima | hypertension, pulmonary | vimentin | cardiovascular diseases | vascular remodeling | DISCOVERY | bone morphogenetic protein receptors, type II | IN-VITRO | sirolimus | TWIST1 protein, human | ARTERIAL-HYPERTENSION | PERIPHERAL VASCULAR DISEASE | epithelial-mesenchymal transition | SMOOTH-MUSCLE-CELLS | KNOCKOUT RATS | TRANSDIFFERENTIATION | Vascular Remodeling | Humans | Gene Expression Profiling | Hypertension, Pulmonary - chemically induced | Actins - genetics | RNA, Messenger - biosynthesis | Vimentin - genetics | Cell Transdifferentiation | Lung - metabolism | Disease Models, Animal | Lung - pathology | Actins - biosynthesis | Bone Morphogenetic Protein Receptors, Type II - genetics | Vimentin - biosynthesis | Cells, Cultured | Rats | Hypertension, Pulmonary - genetics | Hypoxia - complications | Monocrotaline - toxicity | Sirolimus - pharmacology | Animals | Biomarkers | Mutation | Endothelial Cells - pathology | Lung - blood supply | Hypertension, Pulmonary - pathology | Mesoderm - pathology | Bone Morphogenetic Protein Receptors, Type II - biosynthesis | Cell Movement | Life Sciences
Journal Article
Experimental and Molecular Pathology, ISSN 0014-4800, 06/2019, Volume 108, pp. 143 - 149
The dysregulation of microRNA (miRNA) expression has been highlighted in a variety of human malignant conditions with reports implicating a critical role in... 
miR-539 | Epithelial-mesenchymal transition | TWIST1 | Pancreatic cancer
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 12/2019, Volume 1866, Issue 12, p. 118537
The epithelial-mesenchymal transition is a major cause of cancer metastasis, and deregulation of the transcription factor, Twist1, is a critical molecular... 
Cancer stemness | Ubiquitination | HR23A | EMT | Twist1
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 09/2019, Volume 20, Issue 18, p. 4427
Wnt signaling plays a major role in bone metabolism. Advances in our understanding of secreted regulators of Wnt have yielded several therapeutic targets to... 
osteocytes | Wnt | osteoporosis | mechanotransduction | Twist1 | sclerostin
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/2019, Volume 860, p. 172589
Long noncoding RNA cancer susceptibility candidate 15 (CASC15) facilitates progression of hepatocellular carcinoma (HCC) cells, but the molecular mechanisms... 
Hepatocellular carcinoma | TWIST1 | CASC15 | Epithelial-to-mesenchymal transition | NONCODING RNA | OVEREXPRESSION | METASTASIS | PHARMACOLOGY & PHARMACY | CANCER
Journal Article
by Cho, KH and Yu, SL and Cho, DY and Park, CG and Lee, HY
BMC CANCER, ISSN 1471-2407, 10/2015, Volume 15
Background: Cancer metastasis is a multi-step event including epithelial-to-mesenchymal transition (EMT). Breast cancer metastasis suppressor 1 (BRMS1) is a... 
HIF-1 alpha | PROTEIN | TGF-beta 1 | TWIST1 | Snail | HYPOXIA | TWIST1 EXPRESSION | EPITHELIAL-MESENCHYMAL TRANSITION | LUNG-CANCER | INVASION | BRMS1 | GENE | ONCOLOGY | PROMOTES | CARCINOMA METASTASIS
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 15, pp. 12201 - 12211
Triple negative breast cancer (TNBC) still remains a challenge to treat in the clinic due to a lack of good targets for treatment. Although TNBC lacks... 
SOX2 | Slug | c-Myc | CD133 | Twist1
Journal Article
CANCER LETTERS, ISSN 0304-3835, 08/2013, Volume 336, Issue 1, pp. 167 - 173
TGF-beta 1 induces epithelial-mesenchymal transition (EMT) to stimulate cancer cell progression, and TWIST1 is a critical regulator of EMT. In the present... 
EPITHELIAL-MESENCHYMAL TRANSITION | HIF-1 alpha | ONCOLOGY | TGF-beta 1 | STAT3 | TWIST1 | HIF-1-ALPHA | UP-REGULATION | Prostate cancer cell invasion
Journal Article
Nature Communications, ISSN 2041-1723, 06/2017, Volume 8, Issue 1, p. 15773
Recent fate-mapping studies concluded that EMT is not required for metastasis of carcinomas. Here we challenge this conclusion by showing that these studies... 
EPITHELIAL-MESENCHYMAL TRANSITION | PATHWAY | MULTIDISCIPLINARY SCIENCES | GROWTH | TRANSCRIPTION | KINASE | SIX1 | TWIST1 | CHEMORESISTANCE | EXPRESSION | HEDGEHOG
Journal Article
Chinese Journal of Integrative Medicine, ISSN 1672-0415, 2018, Volume 25, Issue 5, pp. 334 - 341
ObjectiveTo evaluate the effects of Celastrus Orbiculatus extracts (COE) on metastasis in hypoxia-induced hepatocellular carcinoma cells (HepG2) and to explore... 
Celastrus Orbiculatus | Hif-1α/Twist1 signaling pathway | epithelial-mesenchymal transition | antimetastasis | hepatocellular carcinoma | Twist1 signaling pathway | INTEGRATIVE & COMPLEMENTARY MEDICINE | Hif-1
Journal Article
by Liu, Y and Meng, FZ and Wang, JB and Liu, MY and Yang, GC and Song, RP and Zheng, TS and Liang, YJ and Zhang, SG and Yin, DL and Wang, JZ and Yang, HY and Pan, SH and Sun, B and Han, JH and Sun, J and Lan, YL and Wang, Y and Liu, XR and Zhu, MX and Cui, YF and Zhang, B and Wu, DH and Liang, SH and Liu, YF and Song, X and Lu, ZY and Yang, JX and Li, M and Liu, LX
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 09/2019, Volume 25, Issue 17, pp. 5407 - 5421
Purpose: As a main rate-limiting subunit of the 2-oxoglutarate dehydrogenase multienzyme complex, oxoglutarate dehydrogenase like (OGDHL) is involved in the... 
EPITHELIAL-MESENCHYMAL TRANSITION | HEPATOCELLULAR-CARCINOMA | IN-VITRO | GENE | ONCOLOGY | RESISTANCE | TWIST1 | PROLIFERATION | TRANSCRIPTION FACTOR | EMT | CYCLE
Journal Article
Cell Death & Differentiation, ISSN 1350-9047, 02/2011, Volume 18, Issue 2, pp. 271 - 281
  A mutation within one allele of the p53 tumor suppressor gene can inactivate the remaining wild-type allele in a dominant-negative manner and in some cases... 
Original Paper | prostate | p53 | Twist1
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2018, Volume 498, Issue 1, pp. 132 - 138
Emerging evidence has indicated that transforming growth factor-beta 1 (TGF-β1) induces the epithelial–mesenchymal transition (EMT) in cancer cells, thus... 
Epithelial–mesenchymal transition (EMT) | Quercetin (Que) | Transforming growth factor-β1 (TGF-β1) | Colorectal cancer (CRC) | E-cadherin | Twist1
Journal Article