Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (1915) 1915
tyrphostins - pharmacology (1870) 1870
life sciences & biomedicine (1834) 1834
animals (1435) 1435
humans (1271) 1271
enzyme inhibitors - pharmacology (977) 977
biological and medical sciences (721) 721
phosphorylation (644) 644
protein-tyrosine kinases - antagonists & inhibitors (630) 630
mice (592) 592
rats (568) 568
male (505) 505
cells, cultured (499) 499
signal transduction (480) 480
signal transduction - drug effects (480) 480
biochemistry & molecular biology (448) 448
quinazolines (448) 448
medical sciences (447) 447
cell biology (432) 432
tyrphostins (432) 432
nitriles - pharmacology (398) 398
female (391) 391
receptor, epidermal growth factor - metabolism (355) 355
cell line (353) 353
oncology (353) 353
cell line, tumor (337) 337
fundamental and applied biological sciences. psychology (319) 319
protein-tyrosine kinases - metabolism (319) 319
receptor, epidermal growth factor - antagonists & inhibitors (318) 318
phosphorylation - drug effects (315) 315
dose-response relationship, drug (284) 284
quinazolines - pharmacology (265) 265
apoptosis - drug effects (257) 257
blotting, western (236) 236
stat3 transcription factor - metabolism (231) 231
pharmacology & pharmacy (230) 230
tumor cells, cultured (224) 224
rats, sprague-dawley (217) 217
protein kinase inhibitors - pharmacology (207) 207
apoptosis (199) 199
antineoplastic agents - pharmacology (195) 195
epidermal growth factor (193) 193
genistein - pharmacology (192) 192
pharmacology. drug treatments (192) 192
cell proliferation - drug effects (187) 187
signal transduction - physiology (187) 187
catechols - pharmacology (180) 180
epidermal growth factor - pharmacology (180) 180
time factors (171) 171
tyrosine - metabolism (171) 171
kinases (166) 166
cell division - drug effects (165) 165
proteins (165) 165
genistein (159) 159
physiology (159) 159
tumors (154) 154
janus kinase 2 (153) 153
abridged index medicus (149) 149
enzyme activation (149) 149
research (148) 148
tyrosine (147) 147
flavonoids - pharmacology (146) 146
janus kinase 2 - metabolism (146) 146
neurosciences & neurology (146) 146
rna, messenger - metabolism (146) 146
stat3 transcription factor - antagonists & inhibitors (143) 143
mitogen-activated protein kinases - metabolism (139) 139
immunology (137) 137
janus kinase 2 - antagonists & inhibitors (137) 137
neurosciences (136) 136
pyridines - pharmacology (136) 136
transfection (132) 132
enzyme activation - drug effects (125) 125
receptor, epidermal growth factor - genetics (124) 124
gene expression (123) 123
isoflavones - pharmacology (123) 123
kinetics (121) 121
mitogen-activated protein kinase 1 - metabolism (121) 121
calcium - metabolism (117) 117
in vitro techniques (117) 117
analysis (116) 116
epidermal growth factor receptor (116) 116
phosphatidylinositol 3-kinases - metabolism (116) 116
cancer (115) 115
research article (115) 115
rats, wistar (114) 114
biophysics (112) 112
cell survival - drug effects (112) 112
reverse transcriptase polymerase chain reaction (112) 112
cardiovascular system & cardiology (106) 106
cell proliferation (106) 106
physiological aspects (105) 105
erbb receptors - metabolism (104) 104
stat3 (102) 102
dna-binding proteins - metabolism (101) 101
mice, inbred c57bl (101) 101
disease models, animal (99) 99
tyrphostin (99) 99
antineoplastic agents (98) 98
endocrinology & metabolism (98) 98
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation
by Li, Baoman and Zhang, Shiquen and Zhang, Hongyan and Nu, Weiwei and Cai, Liping and Hertz, Leif and Peng, Liang
Psychopharmacology, ISSN 0033-3158, 12/2008, Volume 201, Issue 3, pp. 443 - 458
Neurosciences | Biomedicine | Serotonin | Astrocytes | Fluoxetine | EGFR transactivation | fosB | c-fos | Pharmacology/Toxicology | Psychiatry | ERK | 5-HT 2B receptor | receptor | C-fos | FosB | 5-HT | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer | Psychology. Psychoanalysis. Psychiatry | Psychopharmacology | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Neuropharmacology | Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) | Receptor, Epidermal Growth Factor - genetics | Up-Regulation | Phosphorylation | Transcriptional Activation - genetics | Nitriles - pharmacology | Calcium - metabolism | Maleimides - pharmacology | Substrate Specificity | Extracellular Signal-Regulated MAP Kinases - metabolism | Quinazolines | Calcium - chemistry | Receptor, Serotonin, 5-HT2B - physiology | Dose-Response Relationship, Drug | Fluorobenzenes - pharmacology | Receptor, Epidermal Growth Factor - metabolism | Piperidines - pharmacology | Receptor, Serotonin, 5-HT2B - drug effects | Urea - analogs & derivatives | Egtazic Acid - analogs & derivatives | Indoles - pharmacology | Proto-Oncogene Proteins c-fos - antagonists & inhibitors | Astrocytes - drug effects | Fluoxetine - pharmacology | Butadienes - pharmacology | Gene Expression | Signal Transduction | Dipeptides - pharmacology | RNA, Messenger - genetics | Cells, Cultured | Proto-Oncogene Proteins c-fos - metabolism | Antidepressive Agents, Second-Generation - pharmacology | Protein Kinase C - antagonists & inhibitors | Tyrphostins - pharmacology | Chelating Agents - pharmacology | Antidepressive Agents, Second-Generation - antagonists & inhibitors | Fluoxetine - antagonists & inhibitors | Astrocytes - physiology | Animals | Egtazic Acid - pharmacology | Aminopyridines - pharmacology | Proto-Oncogene Proteins c-fos - genetics | Mice | Urea - pharmacology | Brain | Neurotransmitters | Antidepressants | Cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Homocysteine Mediated Expression and Secretion of Monocyte Chemoattractant Protein-1 and Interleukin-8 in Human Monocytes
by Zeng, Xiaokun and Dai, Jing and Remick, Daniel G and Wang, Xian
Circulation research, ISSN 0009-7330, 08/2003, Volume 93, Issue 4, pp. 311 - 320
Monocyte chemoattractant protein-1 | Monocytes | Homocysteine | Interleukin-8 | Atherosclerosis | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Biological and medical sciences | Medical sciences | Atherosclerosis (general aspects, experimental research) | Blood and lymphatic vessels | Interleukin-8 - genetics | Reactive Oxygen Species - metabolism | Chemokine CCL2 - secretion | Monocytes - cytology | Humans | Dimethyl Sulfoxide - pharmacology | Monocytes - metabolism | RNA, Messenger - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Thiocarbamates - pharmacology | Chromans - pharmacology | Time Factors | Homocysteine - pharmacology | Indoles - pharmacology | Interleukin-8 - secretion | Flavonoids - pharmacology | RNA, Messenger - drug effects | RNA, Messenger - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Chemokine CCL2 - genetics | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Monocytes - drug effects | Genistein - pharmacology | Pyridines - pharmacology | Thiazoles - pharmacology | Thiazolidinediones | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Modulation of mast cell proteinase-activated receptor expression and IL-4 release by IL-12
by Zhang, Huiyun and Yang, Xiaoyu and Yang, Haiwei and Zhang, Zhongfang and Lin, Qing and Zheng, Yanshan and Chen, Shaoying and Yang, Pingchang and He, Shaoheng
Immunology and cell biology, ISSN 0818-9641, 10/2007, Volume 85, Issue 7, pp. 558 - 566
mast cell | IL‐4 | IL‐12 | trypsin | protease‐activated receptor | tryptase | IL-4 | Trypsin | Mast cell | Protease-activated receptor | IL-12 | Tryptase | Immunology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Receptors, Proteinase-Activated - metabolism | Nitriles - pharmacology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Receptors, Proteinase-Activated - genetics | Trypsin - pharmacology | Mast Cells - metabolism | Flavonoids - pharmacology | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Interleukin-12 - pharmacology | Butadienes - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Imidazoles - pharmacology | Tyrphostins - pharmacology | Mast Cells - drug effects | Gene Expression Regulation - drug effects | Interleukin-4 - secretion | Animals | Tryptases - pharmacology | Mice | Pyridines - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Tyrphostins, pharmacology | Up-Regulation | Chromones, pharmacology | Trypsin, pharmacology | Humans | Imidazoles, pharmacology | Tryptases, pharmacology | Oligopeptides, pharmacology | Interleukin-12, pharmacology | Flow Cytometry | Pyridines, pharmacology | Polymerase Chain Reaction | Receptor, PAR-1, drug effects | Morpholines, pharmacology | RNA, Messenger, metabolism | Flavonoids, pharmacology | Receptor, PAR-2, drug effects | Receptors, Thrombin, drug effects | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Butadienes, pharmacology | Down-Regulation | Mast Cells, drug effects | Interleukin-6, secretion | Nitriles, pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4, secretion | Fluorescent Antibody Technique | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
by Hua Yuan and Cynthia N. Perry and Chengqun Huang and Eri Iwai-Kanai and Raquel S. Carreira and Christopher C. Glembotski and Roberta A. Gottlieb
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2009, Volume 296, Issue 2, pp. 470 - 479
Green fluorescent protein- Microtubule-associated protein light chain 3 | Lipopolysaccharide | Oxidative stress | Hl-1 cardiac myocyte | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Mitochondria, Heart - metabolism | Glutathione - metabolism | Mitochondria, Heart - pathology | Nitric Oxide Synthase - antagonists & inhibitors | omega-N-Methylarginine - pharmacology | Mitochondria, Heart - drug effects | Nitroprusside - pharmacology | Autophagy - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Donors - pharmacology | Cytoprotection | Animals, Newborn | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mice, Transgenic | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Sirolimus - pharmacology | Hydrogen Peroxide - metabolism | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Mice | Nitric Oxide Synthase - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Signal transduction | Bacteria | Oxidation | Biochemistry | Cytokines | Sugar | Index Medicus | green fluorescent protein-microtubule-associated protein light chain 3 | lipopolysaccharide | HL-1 cardiac myocyte | oxidative stress
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Zinc pyrithione inhibits caspase-3 activity, promotes ErbB1-ErbB2 heterodimerization and suppresses ErbB2 downregulation in cardiomyocytes subjected to ischemia/reperfusion
by Bodiga, Vijaya Lakshmi and Thokala, Sandhya and Vemuri, Praveen Kumar and Bodiga, Sreedhar
Journal of inorganic biochemistry, ISSN 0162-0134, 12/2015, Volume 153, pp. 49 - 59
Hypoxia | Reoxygenation | Proteolysis | Caspase-3 | Zinc | Apoptosis | Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | Receptor, Epidermal Growth Factor - genetics | Caspase Inhibitors - pharmacology | Phosphorylation | Receptor, ErbB-2 - genetics | Protein Multimerization | Caspase 3 - metabolism | Receptor, ErbB-2 - metabolism | RNA, Messenger - metabolism | Cell Hypoxia | Receptor, Epidermal Growth Factor - metabolism | Zinc Compounds - pharmacology | Amino Acid Chloromethyl Ketones - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Benzothiazoles - pharmacology | Chlorides - pharmacology | Down-Regulation | RNA, Messenger - genetics | Rats | Tyrphostins - pharmacology | Cardiotonic Agents - pharmacology | Leupeptins - pharmacology | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Thiones - pharmacology | Quinazolines - pharmacology | Organometallic Compounds - pharmacology | Proteins | Membrane lipids | Inositol | RNA | Antifungal agents | Permeability | Antibacterial agents | Phosphotransferases | Tyrosine | Cell death | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner
by Kiprianova, Irina and Remy, Janina and Milosch, Nelli and Mohrenz, Isabelle V and Seifert, Volker and Aigner, Achim and Kögel, Donat
Neoplasia (New York, N.Y.), ISSN 1476-5586, 2015, Volume 17, Issue 7, pp. 564 - 573
Oncology | Life Sciences & Biomedicine | Science & Technology | Niacinamide - analogs & derivatives | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Cell Survival - genetics | Apoptosis - genetics | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Gene Knockdown Techniques | Activating Transcription Factors - genetics | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | Glioma - pathology | Antineoplastic Agents - pharmacology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Peptide Hydrolases - metabolism | Cytochromes c - secretion | Tyrphostins - pharmacology | Sulfonamides - pharmacology | Piperazines - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Phenylurea Compounds - pharmacology | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Niacinamide - pharmacology | STAT3 Transcription Factor - antagonists & inhibitors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Targeting Stat3 in cancer therapy
by Jing, Naijie and Tweardy, David J
Anti-cancer drugs, ISSN 0959-4973, 07/2005, Volume 16, Issue 6, pp. 601 - 607
Stat3 | Cancer therapy | G-quartet oligodeoxynucleotide | Pharmacology & Pharmacy | Oncology | Life Sciences & Biomedicine | Science & Technology | Neoplasms - metabolism | Cell Cycle Proteins - pharmacology | Transcriptional Activation - genetics | Cell Proliferation | Triterpenes - pharmacology | Apoptosis - drug effects | Humans | Cell Movement - physiology | Plasmids - pharmacology | Oligonucleotides - pharmacology | Angiogenesis Inducing Agents - pharmacology | Anticarcinogenic Agents - pharmacology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Oligonucleotides, Antisense - pharmacology | Signal Transduction - genetics | Tyrphostins - pharmacology | src Homology Domains - physiology | Neoplasms - drug therapy | Animals | Ligands | Protein Conformation | Inhibitor of Apoptosis Proteins - pharmacology | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Protein-Tyrosine Kinases | Phosphopeptides - pharmacology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Combined Treatment of Curcumin and Small Molecule Inhibitors Suppresses Proliferation of A549 and H1299 Human Non‐Small‐Cell Lung Cancer Cells
by Lin, Hui‐Ping and Kuo, Li‐Kuo and Chuu, Chih‐Pin
Phytotherapy research, ISSN 0951-418X, 01/2012, Volume 26, Issue 1, pp. 122 - 126
AG1478 | LY294002 | NSCLC | PD173074 | CAPE | AG1024 | curcumin | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Pharmacognosy. Homeopathy. Health food | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Phenylethyl Alcohol - analogs & derivatives | Plant Extracts - pharmacology | Humans | Biological Availability | Caffeic Acids - pharmacology | Antineoplastic Agents - therapeutic use | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Somatomedins - antagonists & inhibitors | Caffeic Acids - therapeutic use | Antineoplastic Agents - pharmacology | Phytotherapy | Chromones - pharmacology | Drug Therapy, Combination | Chromones - therapeutic use | Morpholines - therapeutic use | NF-kappa B - antagonists & inhibitors | Curcumin - therapeutic use | Carcinoma, Non-Small-Cell Lung - metabolism | Curcumin - pharmacology | Enzyme Inhibitors - pharmacology | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Morpholines - pharmacology | Tyrphostins - pharmacology | Pyrimidines - pharmacology | Enzyme Inhibitors - therapeutic use | Tyrphostins - therapeutic use | Phenylethyl Alcohol - pharmacology | Signal Transduction - drug effects | Pyrimidines - therapeutic use | Quinazolines - therapeutic use | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Cell Proliferation - drug effects | Carcinoma, Non-Small-Cell Lung - drug therapy | Quinazolines - pharmacology | Phenylethyl Alcohol - therapeutic use | Plant Extracts - therapeutic use | Curcuma - chemistry | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text β-amyloid monomers are neuroprotective
by Giuffrida, Maria Laura and Caraci, Filippo and Pignataro, Bruno and Cataldo, Sebastiano and De Bona, Paolo and Bruno, Valeria and Molinaro, Gemma and Pappalardo, Giuseppe and Messina, Angela and Palmigiano, Angelo and Garozzo, Domenico and Nicoletti, Ferdinando and Rizzarelli, Enrico and Copani, Agata
The Journal of neuroscience, ISSN 0270-6474, 08/2009, Volume 29, Issue 34, pp. 10582 - 10587
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Butadienes - pharmacology | Podophyllotoxin - pharmacology | Nitriles - pharmacology | Embryo, Mammalian | Amyloid beta-Peptides - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Peptide Fragments - pharmacology | Tyrphostins - pharmacology | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Peptide Fragments - chemistry | Animals | Excitatory Amino Acid Agonists - toxicity | Neuroprotective Agents - pharmacology | Analysis of Variance | Amyloid beta-Peptides - chemistry | Cell Death - drug effects | Neurons - drug effects | N-Methylaspartate - toxicity | Podophyllotoxin - analogs & derivatives | Index Medicus | Brief Communications
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Diverse intracellular pathogens activate type III interferon expression from peroxisomes
by Odendall, Charlotte and Dixit, Evelyn and Stavru, Fabrizia and Bierne, Helene and Franz, Kate M and Durbin, Ann Fiegen and Boulant, Steeve and Gehrke, Lee and Cossart, Pascale and Kagan, Jonathan C
Nature immunology, ISSN 1529-2908, 2014, Volume 15, Issue 8, pp. 717 - 726
Life Sciences & Biomedicine | Immunology | Science & Technology | Interferons - biosynthesis | Cyclohexanes - pharmacology | Humans | Interferons - immunology | Intestinal Mucosa - cytology | Signal Transduction - immunology | RNA Interference | Intestinal Mucosa - immunology | Reoviridae - immunology | Antineoplastic Agents - pharmacology | Cell Differentiation | Janus Kinase 2 - antagonists & inhibitors | Cell Line | DEAD Box Protein 58 | Peroxisomes - immunology | Reoviridae Infections - immunology | Enzyme Inhibitors - pharmacology | Janus Kinase 2 - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Tyrphostins - pharmacology | Vidarabine - analogs & derivatives | Immunity, Innate | STAT1 Transcription Factor - antagonists & inhibitors | STAT1 Transcription Factor - immunology | Vidarabine - pharmacology | Animals | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | DEAD-box RNA Helicases - immunology | Benzimidazoles - pharmacology | Mice | RNA, Small Interfering | Pyridones - pharmacology | Physiological research | Interferon | Immune response | Research | Properties | Index Medicus | Life Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights