Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
biochemistry & molecular biology (511) 511
humans (453) 453
u1 snrna (345) 345
molecular sequence data (337) 337
base sequence (302) 302
index medicus (296) 296
animals (285) 285
cell biology (262) 262
rna splicing (233) 233
ribonucleoprotein, u1 small nuclear - metabolism (232) 232
pre-messenger-rna (227) 227
u1 snrnp (197) 197
rna, small nuclear - genetics (184) 184
rna (179) 179
hela cells (168) 168
rna, small nuclear - metabolism (166) 166
mutation (153) 153
nucleic acid conformation (148) 148
amino acid sequence (142) 142
rna precursors - metabolism (140) 140
small nuclear ribonucleoprotein (140) 140
genetics & heredity (135) 135
binding sites (131) 131
ribonucleoprotein, u1 small nuclear - genetics (129) 129
proteins (128) 128
splicing (128) 128
ribonucleoprotein, u1 small nuclear - chemistry (121) 121
protein binding (118) 118
identification (117) 117
introns (117) 117
messenger-rna (113) 113
research (111) 111
saccharomyces-cerevisiae (111) 111
spliceosomes - metabolism (107) 107
rna-binding proteins - metabolism (105) 105
spliceosome (102) 102
yeast (98) 98
article (97) 97
exons (95) 95
saccharomyces cerevisiae - genetics (91) 91
research article (90) 90
rna precursors - genetics (90) 90
rna, small nuclear - chemistry (90) 90
u6 snrna (87) 87
small nuclear-rna (86) 86
protein (85) 85
models, molecular (84) 84
alternative splicing (83) 83
complex (79) 79
crystal-structure (77) 77
gene expression (77) 77
transcription, genetic (77) 77
rna, messenger - metabolism (74) 74
recognition (71) 71
rna splicing - genetics (71) 71
cell nucleus - metabolism (69) 69
sr proteins (69) 69
binding (67) 67
genes (67) 67
analysis (63) 63
rna-binding proteins - genetics (63) 63
ribonucleoproteins (62) 62
ribonucleoproteins, small nuclear - metabolism (62) 62
transcription (62) 62
mice (61) 61
rna-binding proteins (61) 61
rna-binding proteins - chemistry (61) 61
messenger rna (60) 60
polyadenylation (59) 59
site selection (59) 59
environment and public health (58) 58
premessenger rna (58) 58
multidisciplinary sciences (57) 57
nuclear proteins - metabolism (57) 57
small nuclear ribonucleoproteins (57) 57
snrna u1 (57) 57
pre-mrna splicing (56) 56
ribonucleoproteins - metabolism (56) 56
genetic aspects (55) 55
in-vitro (55) 55
site (55) 55
secondary structure (54) 54
expression (53) 53
molecular biology (53) 53
snrna (53) 53
cell line (52) 52
protein structure, tertiary (51) 51
rna, messenger - genetics (51) 51
in-vivo (50) 50
rna - metabolism (50) 50
sequence alignment (50) 50
base-pairing interaction (49) 49
rna splice sites (49) 49
spliceosomes (48) 48
biophysics (47) 47
a-protein (46) 46
developmental biology (46) 46
ribonucleic acid--rna (46) 46
invitro (45) 45
spliceosomes - genetics (45) 45
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text A Subset of Drosophila Integrator Proteins Is Essential for Efficient U7 snRNA and Spliceosomal snRNA 3′-End Formation
by Nader Ezzeddine and Jiandong Chen and Bernhard Waltenspiel and Brandon Burch and Todd Albrecht and Ming Zhuo and William D. Warren and William F. Marzluff and Eric J. Wagner
Molecular and Cellular Biology, ISSN 0270-7306, 01/2011, Volume 31, Issue 2, pp. 328 - 341
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
U1 SNRNA | SMALL NUCLEAR-RNA | 3' END FORMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLYADENYLATION FACTOR CPSF-73 | PREMESSENGER RNAS | POLYMERASE-II | MATURATION | HISTONE MESSENGER-RNAS | GENE PROMOTERS | EXPRESSION | CELL BIOLOGY | Spliceosomes - genetics | Humans | Cells, Cultured | Molecular Sequence Data | RNA Polymerase II - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Recombinant Fusion Proteins - metabolism | Protein Subunits - metabolism | Drosophila melanogaster - metabolism | Spliceosomes - metabolism | Animals | RNA Interference | RNA, Small Nuclear - genetics | Base Sequence | Recombinant Fusion Proteins - genetics | RNA Polymerase II - genetics | Drosophila Proteins - genetics | RNA, Small Nuclear - metabolism | 3' Untranslated Regions | Protein Subunits - genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing
by Lardelli, Rea M and Schaffer, Ashleigh E and Eggens, Veerle R. C and Zaki, Maha S and Grainger, Stephanie and Sathe, Shashank and van Nostrand, Eric L and Schlachetzki, Zinayida and Rosti, Basak and Akizu, Naiara and Scott, Eric and Silhavy, Jennifer L and Heckman, Laura Dean and Rosti, Rasim Ozgur and Dikoglu, Esra and Gregor, Anne and Guemez-Gamboa, Alicia and Musaev, Damir and Mande, Rohit and Widjaja, Ari and Shaw, Tim L and Markmiller, Sebastian and Marin-Valencia, Isaac and Davies, Justin H and de Meirleir, Linda and Kayserili, Hulya and Altunoglu, Umut and Freckmann, Mary Louise and Warwick, Linda and Chitayat, David and Blaser, Susan and Çağlayan, Ahmet Okay and Bilguvar, Kaya and Per, Huseyin and Fagerberg, Christina and Christesen, Henrik T and Kibaek, Maria and Aldinger, Kimberly A and Manchester, David and Matsumoto, Naomichi and Muramatsu, Kazuhiro and Saitsu, Hirotomo and Shiina, Masaaki and Ogata, Kazuhiro and Foulds, Nicola and Dobyns, William B and Chi, Neil C and Traver, David and Spaccini, Luigina and Bova, Stefania Maria and Gabriel, Stacey B and Gunel, Murat and Valente, Enza Maria and Nassogne, Marie-Cecile and Bennett, Eric J and Yeo, Gene W and Baas, Frank and Lykke-Andersen, Jens and Gleeson, Joseph G
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 3, pp. 457 - 464
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout evolution and, in mammals,... 
U1 SNRNAS | COMPLEX | SMALL NUCLEAR-RNA | GENETICS & HEREDITY | GENE-EXPRESSION | NEURODEGENERATION | BODIES | MATURATION | PROTEINS | Spliceosomes - genetics | Humans | RNA, Messenger - genetics | Male | Neurodegenerative Diseases - genetics | Zebrafish | Mutation - genetics | Animals | Cerebellar Diseases - genetics | RNA, Small Nuclear - genetics | Alleles | Exonucleases - genetics | Female | Mice | Nuclear Proteins - genetics | Care and treatment | Gene mutations | Exonucleases | Nervous system | Development and progression | Degeneration | Genetic aspects | Gene expression | Health aspects | Proteins | Medical research | Genealogy | Neurodegeneration | Rodents | Genomics | Colleges & universities | Fibroblasts | Genetics | Mutation | Patients | Defects | TOE1 | Pontocerebellar hypoplasia | snRNA | deadenylation | snRNP | CAF1Z
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Binding Affinity and Cooperativity Control U2B″/snRNA/U2A′ RNP Formation
by Williams, Sandra G and Hall, Kathleen B
Biochemistry, ISSN 0006-2960, 06/2014, Volume 53, Issue 23, pp. 3727 - 3737
The U1A and U2B″ proteins are components of the U1 and U2 snRNPs, respectively, where they bind to snRNA stemloops. While localization of U1A and U2B″ to their... 
ISOTHERMAL TITRATION CALORIMETRY | B-PROTEIN | MOLECULAR-DYNAMICS | COMPLEX | U2B | SNRNP-A-PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | U2 SNRNP | NON-NUCLEOTIDE SPACERS | STEM-LOOP | HUMAN U1A PROTEIN | Ribonucleoprotein, U1 Small Nuclear - metabolism | Ribonucleoprotein, U2 Small Nuclear - chemistry | Humans | Protein Multimerization | Molecular Sequence Data | snRNP Core Proteins - metabolism | Thermodynamics | Ribonucleoprotein, U2 Small Nuclear - metabolism | Nucleotide Motifs | Ribonucleoprotein, U1 Small Nuclear - chemistry | Ribonucleoprotein, U2 Small Nuclear - genetics | Protein Interaction Domains and Motifs | Protein Stability | snRNP Core Proteins - genetics | Peptide Fragments - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Peptide Fragments - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Ribonucleoprotein, U1 Small Nuclear - genetics | RNA Stability | Peptide Fragments - chemistry | Sequence Alignment | snRNP Core Proteins - chemistry | RNA, Small Nuclear - chemistry | RNA, Small Nuclear - metabolism | Physiological aspects | Small nuclear ribonucleoproteins | Research | Binding sites (Biochemistry)
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Widespread recognition of 5′ splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides
by Roca, Xavier and Akerman, Martin and Gaus, Hans and Berdeja, Andrés and Bennett, C. Frank and Krainer, Adrian R
Genes and Development, ISSN 0890-9369, 05/2012, Volume 26, Issue 10, pp. 1098 - 1109
An established paradigm in pre-mRNA splicing is the recognition of the 5' splice site (5'ss) by canonical base-pairing to the 5' end of U1 small nuclear RNA... 
Alternative splicing | 5′ splice site | U1 small nuclear RNA | Splicing mutation | Base-pairing register | Bulged nucleotide | bulged nucleotide | 5 ' splice site | alternative splicing | base-pairing register | CRYSTAL-STRUCTURE | DEVELOPMENTAL BIOLOGY | U2 SNRNA | THERMODYNAMIC PARAMETERS | SINGLE NUCLEOTIDE | U6 SNRNA | 5'-SPLICE SITES | CELL BIOLOGY | IN-VITRO | MESSENGER-RNA | COMPARATIVE GENOMICS | GENETICS & HEREDITY | splicing mutation | SMALL NUCLEAR RNAS | Ribonucleotides - chemistry | Alternative Splicing | Base Pairing | RNA Splice Sites - genetics | RNA, Small Nuclear - genetics | Humans | Transcriptome | RNA, Small Nuclear - chemistry | HeLa Cells | Nucleic Acid Conformation | Messenger RNA | Research | Nucleotides | Gene mutations | RNA splicing | Research Paper
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text The conserved AU dinucleotide at the 5′ end of nascent U1 snRNA is optimized for the interaction with nuclear cap-binding-complex
by Yeh, Chung-Shu and Chang, Shang-Lin and Chen, Jui-Hui and Wang, Hsuan-Kai and Chou, Yue-Chang and Wang, Chun-Hsiung and Huang, Shih-Hsin and Larson, Amy and Pleiss, Jeffrey A and Chang, Wei-Hau and Chang, Tien-Hsien
Nucleic Acids Research, ISSN 0305-1048, 09/2017, Volume 45, Issue 16, pp. 9679 - 9693
Splicing is initiated by a productive interaction between the pre-mRNA and the U1 snRNP, in which a short RNA duplex is established between the 5' splice site... 
COMMITMENT COMPLEX | YEAST | SPLICE SITES | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SR PROTEINS | GENETIC INTERACTIONS | PREMESSENGER RNA | PRE-MESSENGER-RNA | RIBOSOMAL-PROTEIN L32 | SCHIZOSACCHAROMYCES-POMBE | Ribonucleoprotein, U1 Small Nuclear - metabolism | Ribonucleoprotein, U1 Small Nuclear - genetics | Saccharomyces cerevisiae Proteins - genetics | Nuclear Cap-Binding Protein Complex - genetics | Nuclear Cap-Binding Protein Complex - metabolism | RNA Cap-Binding Proteins - metabolism | RNA Cap-Binding Proteins - genetics | Yeasts - genetics | RNA Splicing | Base Pairing | RNA, Small Nuclear - genetics | Saccharomyces cerevisiae Proteins - metabolism | Yeasts - growth & development | RNA Precursors - metabolism | RNA, Small Nuclear - chemistry | Molecular Docking Simulation | RNA, Small Nuclear - metabolism | RNA and RNA-protein complexes
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Gemin5 plays a role in unassembled‐U1 snRNA disposal in SMN‐deficient cells
by Jiang, Dongxu and Zou, Xuan and Zhang, Cheng and Chen, Jincao and Li, Zhiqiang and Wang, Yunfu and Deng, Zixin and Wang, Liangrong and Chen, Shi
FEBS Letters, ISSN 0014-5793, 04/2018, Volume 592, Issue 8, pp. 1400 - 1411
Gemin5 acts as a U1 small nuclear RNA (snRNA)‐binding protein in U1 small nuclear ribonucleic protein (snRNP) biogenesis. Here, we report a role for Gemin5 in... 
SMN deficiency | Unassembled U1 snRNA disposal | Gemin5 | PROTEIN | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOTOR-NEURON COMPLEX | IDENTIFICATION | ZINC-FINGER NUCLEASES | CELL BIOLOGY | IN-VITRO | P-BODIES | U1 SNRNP | BIOPHYSICS | SPINAL MUSCULAR-ATROPHY | ASSEMBLY PATHWAY | Ribonucleoprotein, U1 Small Nuclear - metabolism | RNA, Small Nuclear - genetics | Cytoplasmic Granules - metabolism | Humans | Cytoplasmic Granules - genetics | Survival of Motor Neuron 1 Protein - genetics | Ribonucleoprotein, U1 Small Nuclear - genetics | Ribonucleoproteins, Small Nuclear - genetics | HeLa Cells | RNA, Small Nuclear - metabolism | Survival of Motor Neuron 1 Protein - metabolism | Ribonucleoproteins, Small Nuclear - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text snRNA 3′ end formation: The dawn of the Integrator complex
by Chen, Jiandong and Wagner, Eric J
Biochemical Society Transactions, ISSN 0300-5127, 08/2010, Volume 38, Issue 4, pp. 1082 - 1087
The ubiquitously expressed uridine-rich snRNAs (small nuclear RNAs) are essential for the removal of introns, proper expression of histone mRNA and... 
Cleavage and polyadenylation specificity factor (CPSF) | Integrator complex | Small nuclear RNA (snRNA) | RNA cleavage | β-lactamase | RNA polymerase II | RNA-POLYMERASE-II | U1 SNRNA | ELONGATION COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN U2 SNRNA | SMALL NUCLEAR | BINDING-PROTEIN | cleavage and polyadenylation specificity factor (CPSF) | small nuclear RNA (snRNA) | GENE-EXPRESSION | 3'-END FORMATION | beta-lactamase | POLYADENYLATION FACTOR CPSF-73 | HISTONE MESSENGER-RNAS | Transcription, Genetic - physiology | Animals | Models, Biological | RNA 3' End Processing - physiology | Humans | RNA, Small Nuclear - chemistry | RNA, Small Nuclear - metabolism | 3' Flanking Region | Nucleic Acid Conformation | Ribonucleoproteins, Small Nuclear - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text An RNAi screen identifies additional members of the Drosophila Integrator complex and a requirement for cyclin C/Cdk8 in snRNA 3′-end formation
by Chen, Jiandong and Ezzeddine, Nader and Waltenspiel, Bernhard and Albrecht, Todd R and Warren, William D and Marzluff, William F and Wagner, Eric J
RNA, ISSN 1355-8382, 12/2012, Volume 18, Issue 12, pp. 2148 - 2156
Formation of the 3' end of RNA polymerase II-transcribed snRNAs requires a poorly understood group of proteins called the Integrator complex. Here we used a... 
Asunder | Cdk8 | Integrator complex | Cyclin C | RNAPII | snRNA | U1 SNRNA | TERMINAL DOMAIN | 3' END FORMATION | MEDIATOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | KINASE | SMALL NUCLEAR | POLYMERASE-II | HISTONE MESSENGER-RNAS | cyclin C | Cell Line | Species Specificity | Mediator Complex - metabolism | Humans | Cell Cycle Proteins - metabolism | Mediator Complex - genetics | Blood Proteins - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Animals | RNA Interference | Blood Proteins - genetics | RNA, Small Nuclear - genetics | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase 8 - metabolism | Cyclin C - metabolism | Drosophila Proteins - genetics | RNA, Small Nuclear - metabolism | RNA 3' End Processing | Report
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text FTO controls reversible m(6)Am RNA methylation during snRNA biogenesis
by Mauer, J and Sindelar, M and Despic, V and Guez, T and Hawley, BR and Vasseur, JJ and Rentmeister, A and Gross, SS and Pellizzoni, L and Debart, F and Goodarzis, H and Jaffrey, SR
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 04/2019, Volume 15, Issue 4, pp. 340 - 340
Small nuclear RNAs (snRNAs) are core spliceosome components and mediate pre-mRNA splicing. Here we show that snRNAs contain a regulated and reversible... 
U1 SNRNA | N6-METHYLADENOSINE | INHIBITION | SMALL NUCLEAR-RNA | STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRE-MESSENGER-RNAS | IDENTIFICATION | MATURATION | CELL | FAT MASS
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text The C-terminal domain of pol II and a DRB-sensitive kinase are required for 3′ processing of U2 snRNA
by Taylor, Alice and Medlin, Joanne E and Bentley, David L and Uguen, Patricia and Murphy, Shona
The EMBO Journal, ISSN 0261-4189, 02/2003, Volume 22, Issue 4, pp. 925 - 934
The human snRNA genes transcribed by RNA polymerase II (e.g. U1 and U2) have a characteristic TATA‐less promoter containing an essential proximal sequence... 
CTD | transcription | RNA processing | snRNA | pol II | Pol II | Transcription | RNA-POLYMERASE-II | 3'-END | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN U1 | PRE-MESSENGER-RNA | P-TEFB | CELL BIOLOGY | IN-VIVO | GENES | SUBUNIT | Protein Kinases - drug effects | RNA, Small Nuclear - drug effects | Humans | Enzyme Inhibitors - pharmacology | Gene Expression Regulation - physiology | Dichlororibofuranosylbenzimidazole - pharmacology | RNA Processing, Post-Transcriptional - physiology | RNA, Small Nuclear - metabolism | DNA Polymerase II - metabolism | pol II
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text How to Recruit the Correct RNA Polymerase? Lessons from snRNA Genes
by Dergai, Oleksandr and Hernandez, Nouria
Trends in Genetics, ISSN 0168-9525, 06/2019, Volume 35, Issue 6, pp. 457 - 469
Nuclear eukaryotic genomes are transcribed by three related RNA polymerases (Pol), which transcribe distinct gene sets. Specific Pol recruitment is achieved... 
transcription initiation | RNA polymerase | snRNA genes | SNAPc | SEA-URCHIN U1 | NONCODING RNA | DROSOPHILA U1 | PROXIMAL SEQUENCE ELEMENT | III TRANSCRIPTION | CONFORMATIONAL-CHANGE | TATA BOX | PROMOTER ELEMENTS | GENETICS & HEREDITY | MONOCOT PLANTS | BINDING PROTEIN | Arabidopsis thaliana | Anopheles | Promoters (Genetics) | Wildlife conservation | Genes | Genomics | Antisense RNA | Genetic transcription | DNA binding proteins | RNA polymerases
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Gene expression profiling reveals U1 snRNA regulates cancer gene expression
by Cheng, Zhi and Sun, Yu and Niu, Xiaoran and Shang, Yingchun and Ruan, Jishou and Chen, Ze and Gao, Shan and Zhang, Tao
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 68, pp. 112867 - 112874
U1 small nuclear RNA (U1 snRNA), as one of the most abundant ncRNAs in human cells, plays an important role in splicing of pre-mRNAs. Compared to previous... 
Microarray | Gene expression profiling | Over-expression | U1 snRNA | Cancer | microarray | POLYMORPHISMS | RNA | RECEPTOR SIGNALING PATHWAY | ALZHEIMERS-DISEASE | NUCLEAR RIBONUCLEOPROTEIN COMPLEX | cancer | over-expression | gene expression profiling | ASSOCIATION | CELL BIOLOGY
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Expression of human snRNA genes from beginning to end
by Egloff, Sylvain and O'Reilly, Dawn and Murphy, Shona
Biochemical Society Transactions, ISSN 0300-5127, 08/2008, Volume 36, Issue 4, pp. 590 - 594
in addition to protein-coding genes, mammalian pot 11 (RNA polymerase 11) transcribes independent genes for some non-coding RNAs, including the spliceosomal U1... 
C-terminal domain | Small nuclear RNA (snRNA) | Transcription | RNA processing | RNA polymerase II (pol II) | POL-II | PROXIMAL SEQUENCE ELEMENT | transcription | SMALL NUCLEAR-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN U2 SNRNA | HUMAN U1 | small nuclear RNA (snRNA) | MESSENGER-RNA | IN-VIVO | POLYMERASE-II | c-terminal domain | TRANSCRIPTION FACTOR | Animals | Gene Expression Regulation - genetics | RNA, Small Nuclear - genetics | Humans | Protein Binding | RNA Polymerase II - metabolism | RNA, Small Nuclear - metabolism | Transcription, Genetic - genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Modified U1 snRNA and antisense oligonucleotides rescue splice mutations in SLC26A4 that cause hereditary hearing loss
by Lee, Byeonghyeon and Kim, Ye‐Ri and Kim, Sang‐Joo and Goh, Sung‐Ho and Kim, Jong‐Heun and Oh, Se‐Kyung and Baek, Jeong‐In and Kim, Un‐Kyung and Lee, Kyu‐Yup
Human Mutation, ISSN 1059-7794, 08/2019, Volume 40, Issue 8, pp. 1172 - 1180
One of most important factors for messenger RNA (mRNA) transcription is the spliceosomal component U1 small nuclear RNA (snRNA), which recognizes 5′ splicing... 
splicing | SLC26A4 | antisense oligonucleotide | splicing correction | U1 snRNA | PENDRED-SYNDROME | DEFECTS | SMALL NUCLEAR-RNA | GENETIC CAUSES | IDENTIFICATION | CORRECT | FAMILIES | GENETICS & HEREDITY | ENLARGED VESTIBULAR AQUEDUCT | SPECTRUM | INSIGHTS | Genetic aspects | Messenger RNA | Genetic transcription | Hearing loss | Splicing | Transcription | Antisense oligonucleotides | Mutation | Hearing impairment | snRNA | Binding sites
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text The increasing functional repertoire of U1 snRNA
by West, Steven
Biochemical Society Transactions, ISSN 0300-5127, 08/2012, Volume 40, Issue 4, pp. 846 - 849
Splicing is a key process for mRNA maturation, particularly in higher eukaryotes where most protein-coding transcripts contain multiple introns. It is achieved... 
Cleavage | Splicing | Transcription | Polyadenylation | Long terminal repeat | U1 small nuclear RNA (U1 snRNA) | polyadenylation | DEFINITION | II TRANSCRIPTS | COMPLEX | transcription | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUALITY-CONTROL | PRE-MESSENGER-RNA | cleavage | long terminal repeat | GENE-EXPRESSION | POLY(A) POLYMERASE | splicing | SPLICING-INDEPENDENT RECRUITMENT | DONOR SITE | Polyadenylation - genetics | RNA, Small Nuclear - metabolism | RNA, Small Nuclear - genetics | Humans | Polyadenylation - physiology | Terminal Repeat Sequences - genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Defining essential elements and genetic interactions of the yeast Lsm2–8 ring and demonstration that essentiality of Lsm2–8 is bypassed via overexpression of U6 snRNA or the U6 snRNP subunit Prp24
by Roth, Allen J and Shuman, Stewart and Schwer, Beate
RNA, ISSN 1355-8382, 06/2018, Volume 24, Issue 6, pp. 853 - 864
A seven-subunit Lsm2-8 protein ring assembles on the U-rich 3' end of the U6 snRNA. A structure-guided mutational analysis of the Saccharomyces cerevisiae... 
Lsm proteins | mRNA splicing | Prp24 | U6 snRNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPLICEOSOME | CRYSTAL-STRUCTURES | CAP-BINDING COMPLEX | SACCHAROMYCES-CEREVISIAE | PRE-MESSENGER-RNA | 3' END | U1 SNRNP | SMALL NUCLEAR RIBONUCLEOPROTEIN | MUTATIONS | SM-LIKE PROTEINS | Amino Acid Sequence | Sequence Deletion | Saccharomyces cerevisiae - genetics | Ribonucleoproteins, Small Nuclear - genetics | Saccharomyces cerevisiae Proteins - genetics | Saccharomyces cerevisiae - metabolism | RNA Splicing | RNA, Small Nuclear - genetics | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | RNA, Fungal - genetics | Mutation | RNA, Small Nuclear - metabolism | Binding Sites | Ribonucleoproteins, Small Nuclear - metabolism | Saccharomyces cerevisiae - growth & development
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights