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PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 1, p. e30264
NK cells have therapeutic potential for a wide variety of human malignancies. However, because NK cells expand poorly in vitro, have limited life spans in vivo... 
MOUSE NK CELLS | GAMMA PRODUCTION | CELLULAR CYTOTOXICITY ADCC | ADOPTIVE TRANSFER | SCALE EXPANSION | MULTIDISCIPLINARY SCIENCES | IN-VITRO EXPANSION | PERIPHERAL-BLOOD | MONOCLONAL-ANTIBODY | CLINICAL-GRADE | CD8(+) T-CELLS | Cell Proliferation | Artificial Cells - immunology | Coculture Techniques | Humans | Antibody-Dependent Cell Cytotoxicity - immunology | Gene Expression Profiling | Interleukin-15 - immunology | Interleukins - metabolism | Flow Cytometry | T-Lymphocytes - metabolism | U937 Cells | Interleukins - immunology | Receptors, KIR - metabolism | Killer Cells, Natural - immunology | Membrane Proteins - metabolism | Telomere - genetics | Cell Line | Antigen-Presenting Cells - metabolism | Immunotherapy, Adoptive - methods | Cells, Cultured | Immunophenotyping | Membrane Proteins - immunology | Antigen-Presenting Cells - immunology | Artificial Cells - metabolism | Interleukin-15 - metabolism | K562 Cells | Cell Line, Tumor | T-Lymphocytes - immunology | Killer Cells, Natural - metabolism | Receptors, KIR - immunology | Antigens | Fc receptors | Telomeres | Killer cells | Health aspects | Immunotherapy | Cell proliferation | Lymphocyte receptors | Cell culture | Pediatrics | Senescence | Transplants & implants | Transcription | Toxicity | Adoptive immunotherapy | Erythrocytes | Multiple myeloma | Science | Clinical trials | Cytotoxicity | Leukocytes | Cancer therapies | NKG2 antigen | Cell growth | Lymphocytes | Interleukin 21 | Killer cell immunoglobulin-like receptors | Biocompatibility | Natural killer cells | Expansion | Killing | Cytomegalovirus | Cytokines | Dendritic cells | Blood cells | T cell receptors | Tumor cell lines | Gene expression | Interleukin 15 | White blood cells | CD16 antigen | Biopsy | Antigen-presenting cells | Human performance | Ligands | Genetic engineering
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 474, Issue 7353, pp. 654 - 657
Journal Article
PloS one, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0168092
...)-treated human aortic smooth muscle cells (HASMCs) and identify the underlying mechanism responsible for these effects... 
MYELOLEUKEMIC U937 CELLS | POTENT ANTIINFLAMMATORY AGENT | ENDOTHELIAL PROGENITOR CELLS | SUPEROXIDE ANION | ACTIVATED PROTEIN-KINASE | LECTIN-INDUCED APOPTOSIS | HEPATOCARCINOMA CELLS | MULTIDISCIPLINARY SCIENCES | VISCUM-COLORATUM | II-INDUCED APOPTOSIS | KAPPA-B | Cell Cycle - genetics | Humans | Immunoblotting | Male | NF-kappa B - metabolism | Biphenyl Compounds - therapeutic use | Transcription Factor AP-1 - metabolism | Cell Movement - genetics | Biphenyl Compounds - pharmacology | Propane - analogs & derivatives | Hyperplasia - drug therapy | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Hyperplasia - metabolism | In Situ Nick-End Labeling | Cell Proliferation - genetics | Mice, Inbred C57BL | Cells, Cultured | Platelet-Derived Growth Factor - pharmacology | Neointima - metabolism | Cell Movement - drug effects | Animals | Neointima - drug therapy | Propane - therapeutic use | Fluorescent Antibody Technique | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Propane - pharmacology | Cell proliferation | Prevention | Blood circulation disorders | Usage | Care and treatment | Platelet-derived growth factor | Hyperplasia | Muscle cells | Genetic aspects | Research | Materia medica, Vegetable | Plant extracts | GTP-binding protein | Femoral artery | Transcription factors | Phosphorylation | Femur | Senescence | Disease | AKT protein | Smooth muscle | Biology | Kinases | Cyclin D1 | Cyclin-dependent kinase 4 | Cell adhesion & migration | Proteins | Cell growth | Blood platelets | Atherosclerosis | Cell cycle | Tumor necrosis factor-TNF | Aorta | Cyclin E | Pretreatment | Telomerase | Growth factors | c-Fos protein | G1 phase | Hypertension | Medical treatment | Activator protein 1 | Muscles | Extracellular signal-regulated kinase | JNK protein | Inflammation | Gene expression | Thrombosis | Platelet-derived growth factor BB | Chromatography | Cyclin-dependent kinase 2 | Medicine | Herbal medicine | Cyclin-dependent kinase inhibitor p21 | Hospitals | Natural products | Cell migration
Journal Article
The Journal of clinical investigation, ISSN 1558-8238, 2019, Volume 129, Issue 5, pp. 2094 - 2106
A key mechanism of tumor resistance to immune cells is mediated by expression of peptide-loaded HLA class I molecule (HLA-E... 
Innate immunity | Oncology | NK cells | Immunology | Immunotherapy | MEDICINE, RESEARCH & EXPERIMENTAL | NATURAL-KILLER-CELLS | CD94 | RECOGNITION | IMMUNOTHERAPY | IFN-GAMMA | CD94/NKG2A | CYTOTOXICITY | T-CELLS | HLA-E | LYMPHOCYTES | Neoplasm Transplantation | Immunotherapy - methods | NK Cell Lectin-Like Receptor Subfamily C - metabolism | NK Cell Lectin-Like Receptor Subfamily C - antagonists & inhibitors | Down-Regulation | Humans | Gene Expression Regulation, Neoplastic | Histocompatibility Antigens Class I - immunology | Endoplasmic Reticulum - metabolism | Drug Resistance, Neoplasm | Gene Expression Profiling | Mice, SCID | Animals | U937 Cells | K562 Cells | Cell Line, Tumor | Protein Domains | Mice, Inbred NOD | Mice | Killer Cells, Natural - metabolism | NK Cell Lectin-Like Receptor Subfamily D - metabolism | Receptors, Immunologic - metabolism | Cytotoxicity, Immunologic | Killer cells | Usage | Genetic aspects | Research | Gene expression | Tumors | Viral antibodies | Histocompatibility antigens | HLA histocompatibility antigens | Antibodies | Cancer | Cell proliferation | Peptides | Leukemia | Cytotoxicity | Genomes | NKG2 antigen | Lymphocytes | Peripheral blood | Natural killer cells | Bioinformatics | CRISPR | Antigens | Cytokines | Tumor cells | Immunodeficiency | Immune checkpoint | Stem cells | Antitumor activity | Protein expression | Histocompatibility antigen HLA | Endoplasmic reticulum
Journal Article
Journal of cellular and molecular medicine, ISSN 1582-1838, 2012, Volume 16, Issue 9, pp. 2208 - 2218
Cells derived from the amniotic foetal membrane of human term placenta have drawn particular attention mainly for their plasticity and immunological properties, which render them interesting for stem... 
placenta | mesenchymal stem/stromal cells | cancer cell lines | cell proliferation | amniotic membrane | amnion‐derived cells | Cell proliferation | Amniotic membrane | Placenta | Amnion-derived cells | Cancer cell lines | Mesenchymal stem/stromal cells | MEDICINE, RESEARCH & EXPERIMENTAL | amnion-derived cells | TUMOR-CELLS | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | TERM PLACENTA | THERAPY | mesenchymal stem | stromal cells | IN-VIVO | GROWTH | BONE | DIFFERENTIATION | T-CELLS | Cyclin D2 - genetics | Oncogene Proteins - genetics | Up-Regulation | Cyclin D2 - metabolism | Coculture Techniques | Cyclin-Dependent Kinase 4 - genetics | Humans | G1 Phase - drug effects | RNA, Messenger - metabolism | Cyclin E - genetics | Amnion - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Cyclin-Dependent Kinase Inhibitor p15 - genetics | U937 Cells | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Amnion - cytology | Down-Regulation | RNA, Messenger - genetics | Cyclin-Dependent Kinase 6 - genetics | Oncogene Proteins - metabolism | Cyclin-Dependent Kinase 2 - genetics | Cyclin-Dependent Kinase 6 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Cell Division - drug effects | Cyclin H - metabolism | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Cyclin E - metabolism | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | HeLa Cells | Cyclin H - genetics | RNA | Dendritic cells | Oncology, Experimental | Cell cycle | Stem cells | Research | Gene expression | Cancer | Biotechnology | Mesenchyme | Leukemia | Metastasis | Kinases | Experiments | Cyclin-dependent kinase 4 | Cyclin D2 | Cell growth | Immunology | Lymphocytes | Penicillin | Fibroblasts | G1 phase | Therapeutic applications | Tumor cell lines | Cyclins | Cyclin-dependent kinase 2 | Studies | Monocytes | Biopsy | S phase | Lymphomas | Apoptosis | Tumors | Original
Journal Article
PloS one, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e70430
.... Proliferating cell nuclear antigen (PCNA) is a multifunctional protein essential for DNA replication and repair that is often overexpressed in cancer cells... 
SURVIVAL | PCNA-BINDING | REPLICATION | DNA | MULTIDISCIPLINARY SCIENCES | DISEASE | SENSITIVITY | THERAPIES | DISRUPTS | IDENTIFICATION | INHIBITOR | Apoptosis - drug effects | Humans | Molecular Sequence Data | Antineoplastic Agents - metabolism | Cell-Penetrating Peptides - pharmacology | Multiple Myeloma - drug therapy | Proliferating Cell Nuclear Antigen - genetics | U937 Cells | Protein Binding - drug effects | Antineoplastic Agents - pharmacology | Melphalan - pharmacology | Tumor Cells, Cultured | Amino Acid Sequence | Cell Survival - drug effects | Cell-Penetrating Peptides - genetics | Cells, Cultured | Mice, SCID | Multiple Myeloma - metabolism | Drug Synergism | Xenograft Model Antitumor Assays | Microscopy, Confocal | Multiple Myeloma - pathology | Animals | Cell Line, Tumor | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | HeLa Cells | Amino Acid Motifs - genetics | Proliferating Cell Nuclear Antigen - metabolism | Cell-Penetrating Peptides - metabolism | Proteins | Antigens | DNA replication | Therapeutics | Multiple myeloma | Homeopathy | Materia medica and therapeutics | Apoptosis | Peptides | DNA damage | Science | Homology | Amino acids | Malignancy | DNA repair | Anticancer properties | Cell growth | Antitumor agents | Pathways | Lymphocytes | Melphalan | Proliferating cell nuclear antigen | Xenografts | Cell cycle | Bone marrow | Deoxyribonucleic acid--DNA | Medical research | Hematology | Amino acid sequence | Caspase | Tumor cell lines | Medicine | DNA biosynthesis | Sensitivity | Bone cancer | Stromal cells | Strategy | Protein interaction | Cellular stress response | Cancer | Deoxyribonucleic acid
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23315
...) towards human tumor cells. To enhance PS efficiency, we recently covalently linked a porphyrin (TrMPyP) to a plant lectin (Morniga G... 
HUMAN-COLON-CANCER | GROWTH-FACTOR RECEPTOR | OXIDATIVE STRESS | LYMPHOCYTIC-LEUKEMIA | PHOTODYNAMIC THERAPY | INDUCED APOPTOSIS | ANTIOXIDANT STATUS | MULTIDISCIPLINARY SCIENCES | SIALOSYL-TN | JACALIN-RELATED LECTINS | FLUORESCENT-PROBES | Leukemia - pathology | Photosensitizing Agents - chemistry | Apoptosis - drug effects | Apoptosis - radiation effects | Photochemotherapy - methods | Humans | Porphyrins - chemistry | Leukemia - metabolism | Dose-Response Relationship, Drug | Photosensitizing Agents - pharmacology | Caspases - metabolism | U937 Cells | Plant Lectins - chemistry | Cell Line | Cell Survival - drug effects | Jurkat Cells | Cells, Cultured | Leukemia - drug therapy | Plant Lectins - pharmacology | Porphyrins - pharmacology | Cell Survival - radiation effects | Antigens, Tumor-Associated, Carbohydrate - metabolism | K562 Cells | Cell Line, Tumor | HL-60 Cells | Antigens | Cell death | Leukemia | Plant lectins | T cells | Photochemotherapy | Cancer | Porphyrins | Laboratories | Biochemistry | Lymphocytes T | Leukocytes | Cancer therapies | Cell activation | Lymphocytes | Gangrene | Chronic lymphatic leukemia | Photodynamic therapy | Tumor cells | Mortality | Caspase | Breast cancer | Glycosylation | Lymphatic leukemia | Glycan | White blood cells | Phototoxicity | Lectins | Conjugation | Solid tumors | Tumors | Apoptosis
Journal Article
PloS one, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, p. e113480
.... They have been found to exert anti-inflammatory and pro-resolving responses in macrophages, neutrophils and bronchial epithelial cells and impart beneficial actions in murine models of peritonitis and colitis... 
ADHESION MOLECULE-1 | OXIDATIVE STRESS | MULTIDISCIPLINARY SCIENCES | E-SELECTIN | TRANSCRIPTION | NECROSIS-FACTOR-ALPHA | NF-KAPPA-B | HUMAN PHAGOCYTES | EXPRESSION | MICROARRAY ANALYSIS | CAMP | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Reactive Oxygen Species - metabolism | Muscle, Smooth, Vascular - metabolism | Endothelial Cells - metabolism | Humans | Cells, Cultured | NADPH Oxidases - metabolism | E-Selectin - metabolism | NF-kappa B - metabolism | Cell Adhesion - drug effects | Down-Regulation - drug effects | Muscle, Smooth, Vascular - cytology | Up-Regulation - drug effects | Docosahexaenoic Acids - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | Endothelial Cells - cytology | U937 Cells | Oxidative Stress - drug effects | Cyclic AMP - metabolism | Endothelial Cells - drug effects | Muscle, Smooth, Vascular - drug effects | Oxidative stress | Animal models | Angioplasty | Epithelial cells | Gene regulation | Homeostasis | Intracellular signalling | Smooth muscle | Lipids | Kinases | Macrophages | Docosahexaenoic acid | Cell surface | NAD(P)H oxidase | Cell adhesion & migration | Signal transduction | Cell activation | NOX4 protein | Pathways | Surgery | Penicillin | CYBB protein | Attenuation | Peritonitis | Translocation | Edema | NF-κB protein | Oxygen | Neutrophils | Muscles | Cyclic AMP | Leukocytes (neutrophilic) | Inflammation | Fatty acids | Adhesion | Biological activity | Nuclear transport | Endothelial cells | Studies | E-selectin | Monocytes | Intracellular | Colitis | Alzheimers disease | Human behavior
Journal Article
PloS one, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e114446 - e114446
... endothelial and mononuclear cells. Given the role of reactive oxygen species (ROS) and inflammation in vascular thrombosis, the objective of this study was to evaluate... 
OXIDATIVE STRESS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | UREMIC TOXICITY | ORGAN DAMAGE | CARDIOVASCULAR-DISEASES | DYSFUNCTION | CHRONIC KIDNEY-DISEASE | DENTAL-PULP CELLS | PLASMINOGEN-ACTIVATOR RECEPTOR | FUNCTION IN-VITRO | Leukocytes, Mononuclear - metabolism | Receptors, Urokinase Plasminogen Activator - chemistry | Cresols - toxicity | Leukocytes, Mononuclear - drug effects | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Endothelial Cells - metabolism | Humans | Solubility | Atherosclerosis - metabolism | Dinoprost - biosynthesis | Leukocytes, Mononuclear - pathology | Plasminogen Activator Inhibitor 1 - biosynthesis | Receptors, Urokinase Plasminogen Activator - biosynthesis | Inflammation - metabolism | Cell Cycle Checkpoints - drug effects | U937 Cells | Urokinase-Type Plasminogen Activator - biosynthesis | Cell Proliferation - drug effects | Endothelial Cells - pathology | Endothelial Cells - drug effects | Enzymes | Analysis | Cell cycle | Atherosclerosis | Pesticides | Fluorescence | Kidney diseases | Thrombosis | Enzyme-linked immunosorbent assay | Blood clot | Endothelium | Cytotoxicity | Leukocytes (mononuclear) | Smooth muscle | Propidium iodide | Assaying | Urokinase | Cell growth | Cresols | Inhibition | Thromboembolism | Iodides | Immunomodulation | Polyamide-imides | Wounds | Metabolism | Patients | U-Plasminogen activator | Hospitals | Arteriosclerosis | Stem cells | Viability | Cell migration | Oxidative stress | Flow cytometry | Toxicity | Bleeding | Modulators | Cresol | p-Cresol | Agrochemicals | Blood platelets | Metabolites | Resins | Oxygen | Antiseptics | Complications | Inflammation | Dentistry | Endothelial cells | Cytometry | Cell number | Coal tar | Plasminogen activator inhibitors | Intoxication | Diabetes | Uremia | Index Medicus
Journal Article