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2cl (1) 1
2cl− co-transporter (1) 1
2cl− co-transporter 2 (1) 1
accelerated publication (1) 1
adapter (1) 1
alanine-rich kinase (1) 1
amino acid substitution (1) 1
biochemistry & molecular biology (1) 1
blood-pressure (1) 1
btb domain (1) 1
btb-kelch proteins (1) 1
carrier proteins - genetics (1) 1
carrier proteins - metabolism (1) 1
cl (1) 1
cl− co-transporter (1) 1
co-transporter (1) 1
co-transporter 2 (1) 1
crl, cullin–ring e3 ligase (1) 1
cul3, cullin-3 (1) 1
cullin proteins - genetics (1) 1
cullin proteins - metabolism (1) 1
cullin-ring e3 ligase (1) 1
cullin–ring e3 ligase (1) 1
dct, distal convoluted tubule (1) 1
dominant retinitis-pigmentosa (1) 1
dtt, dithiothreitol (1) 1
gapdh, glyceraldehyde-3-phosphate dehydrogenase (1) 1
gfp, green fluorescent protein (1) 1
gst, glutathione transferase (1) 1
hek, human embryonic kidney (1) 1
hek293 cells (1) 1
hela cells (1) 1
hrp, horseradish peroxidase (1) 1
humans (1) 1
index medicus (1) 1
intracellular signaling peptides and proteins - genetics (1) 1
intracellular signaling peptides and proteins - metabolism (1) 1
keap1, kelch-like ech-associated protein 1 (1) 1
kelch-like domain (1) 1
kinases (1) 1
klhl3, kelch-like 3 (1) 1
lc, liquid chromatography (1) 1
minor histocompatibility antigens (1) 1
mutation, missense (1) 1
na+ (1) 1
na+-cl-cotransporter (1) 1
na+/cl- co-transporter (1) 1
na+/cl− co-transporter (1) 1
na+/k+/2cl co-transporter 2 (1) 1
na+/k+/2cl− co-transporter 2 (1) 1
ncc, na+ (1) 1
ncc, na+/cl− co-transporter (1) 1
nkcc, na+ (1) 1
nkcc, na+/k+/2cl− co-transporter (1) 1
nrf2, nf-e2-related factor 2 (1) 1
osr1 (1) 1
osr1, oxidative stress-responsive kinase 1 (1) 1
oxidative stress-responsive kinase 1 (spak (1) 1
protein-serine-threonine kinases - genetics (1) 1
protein-serine-threonine kinases - metabolism (1) 1
pseudohypoaldosteronism - enzymology (1) 1
pseudohypoaldosteronism - genetics (1) 1
pseudohypoaldosteronism type-ii (1) 1
qrt-pcr, real time quantitative reverse transcription pcr (1) 1
rbx1, ring-box 1, e3 ubiquitin protein ligase (1) 1
ring ubiquitin ligases (1) 1
rpl13a, ribosomal protein l13a (1) 1
rt, reverse transcription (1) 1
rtev, recombinant tobacco etch virus (1) 1
sirna, small interfering rna (1) 1
sodium-potassium-chloride symporters - genetics (1) 1
sodium-potassium-chloride symporters - metabolism (1) 1
solute carrier family 12, member 2 (1) 1
spak (1) 1
spak, sps1-related proline (1) 1
spak, sps1-related proline/alanine-rich kinase (1) 1
sps1-related proline (1) 1
sps1-related proline/alanine-rich kinase/oxidative stress-responsive kinase 1 (1) 1
tal, thick ascending limb (1) 1
transcription factors - genetics (1) 1
transcription factors - metabolism (1) 1
ttbs, tris-buffered saline containing tween 20 (1) 1
ube1, ubiquitin-like modifier-activating enzyme 1 (1) 1
ube2d3, ubiquitin-conjugating enzyme e2 d3 (1) 1
ubiquitin (1) 1
ubiquitination (1) 1
urogenital system (1) 1
wnk lysine-deficient protein kinase 1 (1) 1
wnk, with no lysine kinase (1) 1
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Biochemical Journal, ISSN 0264-6021, 04/2013, Volume 451, Issue 1, pp. 111 - 122
The WNK (with no lysine kinase)-SPAK (SPS1-related proline/alanine-rich kinase)/OSR1 (oxidative stress-responsive kinase 1) signalling pathway plays an... 
Ubiquitin | Cullin-RING E3 ligase (CRL) | SPS1-related proline/alanine-rich kinase/oxidative stress-responsive kinase 1 (SPAK/OSR1) | co-transporter (NCC) | co-transporter 2 (NKCC2) | BTB domain | Cl | 2Cl | Kelch-like domain (KLHL domain) | SPAK | OSR1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | Na+/K+/2Cl(-) co-transporter 2 (NKCC2) | ubiquitin | BLOOD-PRESSURE | DOMINANT RETINITIS-PIGMENTOSA | Na+/Cl- co-transporter (NCC) | NA+-CL-COTRANSPORTER | PSEUDOHYPOALDOSTERONISM TYPE-II | ADAPTER | BTB-KELCH PROTEINS | RING UBIQUITIN LIGASES | KINASES | Minor Histocompatibility Antigens | Pseudohypoaldosteronism - genetics | Humans | Protein-Serine-Threonine Kinases - genetics | Sodium-Potassium-Chloride Symporters - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Mutation, Missense | Transcription Factors - genetics | Sodium-Potassium-Chloride Symporters - metabolism | Cullin Proteins - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Pseudohypoaldosteronism - enzymology | Ubiquitination | Carrier Proteins - metabolism | Solute Carrier Family 12, Member 2 | WNK Lysine-Deficient Protein Kinase 1 | HEK293 Cells | Cullin Proteins - metabolism | HeLa Cells | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Amino Acid Substitution | HEK, human embryonic kidney | 2Cl− co-transporter | RT, reverse transcription | TTBS, Tris-buffered saline containing Tween 20 | DTT, dithiothreitol | rTEV, recombinant tobacco etch virus | HRP, horseradish peroxidase | LC, liquid chromatography | UBE2D3, ubiquitin-conjugating enzyme E2 D3 | qRT-PCR, real time quantitative reverse transcription PCR | TAL, thick ascending limb | OSR1, oxidative stress-responsive kinase 1 | GST, glutathione transferase | RBX1, RING-box 1, E3 ubiquitin protein ligase | 2Cl− co-transporter 2 (NKCC2) | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | UBE1, ubiquitin-like modifier-activating enzyme 1 | Cullin–RING E3 ligase (CRL) | GFP, green fluorescent protein | Cl− co-transporter | NKCC, Na+ | DCT, distal convoluted tubule | KEAP1, Kelch-like ECH-associated protein 1 | CRL, Cullin–RING E3 ligase | SPAK, SPS1-related proline | Accelerated Publication | Cl− co-transporter (NCC) | siRNA, small interfering RNA | NRF2, NF-E2-related factor 2 | oxidative stress-responsive kinase 1 (SPAK | WNK, with no lysine kinase | RPL13A, ribosomal protein L13a | KLHL3, Kelch-like 3 | CUL3, Cullin-3 | Na+ | SPS1-related proline | NCC, Na+ | alanine-rich kinase
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