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1. Full Text The GPER1/SPOP axis mediates ubiquitination-dependent degradation of ERα to inhibit the growth of breast cancer induced by oestrogen
by Zhang, Nan and Sun, Peng and Xu, Yuanyuan and Li, Haiyan and Liu, Huatao and Wang, Ling and Cao, Yue and Zhou, Kewen and TinghuaiWang
Cancer letters, ISSN 0304-3835, 02/2021, Volume 498, pp. 54 - 69
Hormone receptor | GPCR | Nuclear receptor | Protein interaction | Ubiquitin-proteasome pathway | Index Medicus
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2. Full Text The therapeutic potential of PROTACs
Expert opinion on therapeutic patents, 01/2021, pp. 1 - 23
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3. Full Text Dexamethasone acutely suppresses the anabolic SNAT2/SLC38A2 amino acid transporter protein in L6‐G8C5 rat skeletal muscle cells
by Blbas, Safia and Watson, Emma and Butler, Heather and Brown, Jeremy and Herbert, Terence P and Stover, Cordula M and Bevington, Alan and Abbasian, Nima
FASEB bioAdvances, ISSN 2573-9832, 01/2021, Volume 3, Issue 1, pp. 36 - 48
dexamethasone | glucocorticoid | SNAT2 | skeletal muscle | SLC38A2 | ubiquitin‐proteasome pathway | Glucocorticoids | Transcription | Amino acids | Immunoblotting | Cell fusion | Kinases | pH effects | Experiments | Mammalian cells | Proteins | Proteolysis | Protein transport | Fusion protein | Metabolic acidosis | Dexamethasone | Myotubes | Cachexia | Fluorides | Metabolism | Proteasome inhibitors | Skeletal muscle | Musculoskeletal system | Hypotheses | Plasmids | Protein synthesis | Acidosis
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4. Full Text The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions
by Oughtred, Rose and Rust, Jennifer and Chang, Christie and Breitkreutz, Bobby‐Joe and Stark, Chris and Willems, Andrew and Boucher, Lorrie and Leung, Genie and Kolas, Nadine and Zhang, Frederick and Dolma, Sonam and Coulombe‐Huntington, Jasmin and Chatr‐aryamontri, Andrew and Dolinski, Kara and Tyers, Mike
Protein science, ISSN 0961-8368, 01/2021, Volume 30, Issue 1, pp. 187 - 200
phenotype | biological network | protein interaction | COVID‐19 | chemical interaction | CRISPR screen | drug target | ubiquitin‐proteasome system | genetic interaction | post‐translational modification | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Proteins - genetics | COVID-19 - virology | SARS-CoV-2 - genetics | User-Computer Interface | Animals | SARS-CoV-2 - pathogenicity | Humans | Mice | COVID-19 - genetics | Databases, Factual | Protein Interaction Mapping | Animal experimentation | Post-translational modification | Ubiquitin | Medical research | Databases | Visualization (Computers) | Analysis | Genomics | Severe acute respiratory syndrome | Medicine, Experimental | Health aspects | Repositories | CRISPR | Yeasts | Phenotypes | Viral diseases | Zebrafish | Viruses | Genomes | Genetic screening | Datasets | Residential areas | Severe acute respiratory syndrome coronavirus 2 | COVID-19 | Proteins | Annotations | Respiratory diseases | Data sets | Cell lines | Chemical interactions | Index Medicus
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5. Full Text Association between plasma immunoproteasome and 90-day prognosis after first-ever ischemic stroke
by Chen, Xing-Yong and Fu, Ming and Wan, Shao-Fen and Zhang, Xu and Wang, Yin-Zhou
Neural regeneration research, ISSN 1673-5374, 4/2021, Volume 16, Issue 4, pp. 790 - 795
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Stroke (Disease) | Complications and side effects | Prognosis | Biological markers | Ubiquitin-proteasome system | Health aspects | Immunoproteins | behavior; biomarker; brain; clinical trial; cognitive impairment; immune function; neurological function; protein; stroke
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6. Full Text Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system
by Wu, Xiaomin and Sun, Xutong and Sharma, Shruti and Lu, Qing and Yegambaram, Manivannan and Hou, Yali and Wang, Ting and Fineman, Jeffrey R and Black, Stephen M
Nitric oxide, 12/2020, Volume 108, pp. 12 - 19
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7. Full Text Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development
by Donovan, Katherine A and Ferguson, Fleur M and Bushman, Jonathan W and Eleuteri, Nicholas A and Bhunia, Debabrata and Ryu, SeongShick and Tan, Li and Shi, Kun and Yue, Hong and Liu, Xiaoxi and Dobrovolsky, Dennis and Jiang, Baishan and Wang, Jinhua and Hao, Mingfeng and You, Inchul and Teng, Mingxing and Liang, Yanke and Hatcher, John and Li, Zhengnian and Manz, Theresa D and Groendyke, Brian and Hu, Wanyi and Nam, Yunju and Sengupta, Sandip and Cho, Hanna and Shin, Injae and Agius, Michael P and Ghobrial, Irene M and Ma, Michelle W and Che, Jianwei and Buhrlage, Sara J and Sim, Taebo and Gray, Nathanael S and Fischer, Eric S
Cell (Cambridge), ISSN 0092-8674, 12/2020, Volume 183, Issue 6, pp. 1714 - 1731.e10
kinase | E3 ligase | PROTAC | ubiquitin proteasome system | targeted degradation | IMiD | ubiquitin | degrader | Index Medicus
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8. Full Text Disrupted ubiquitin proteasome system underlying tau accumulation in Alzheimer's disease
Neurobiology of aging, 12/2020, Volume 99, pp. 79 - 85
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9. Full Text The ubiquitin proteasome system is necessary for efficient proliferation of porcine reproductive and respiratory syndrome virus
by Pang, Yu and Li, Mao and Zhou, Yanrong and Liu, Wei and Tao, Ran and Zhang, Hejin and Xiao, Shaobo and Fang, Liurong
Veterinary microbiology, ISSN 0378-1135, 02/2021, Volume 253, pp. 108947 - 108947
Porcine reproductive and respiratory syndrome virus (PRRSV) | MG132 | Ubiquitin-proteasome system (UPS) | Viral replication | Free ubiquitin | Poly-ubiquitin | Index Medicus
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10. Full Text The intrinsic proteostasis network of stem cells
by Llamas, Ernesto and Alirzayeva, Hafiza and Loureiro, Rute and Vilchez, David
Current opinion in cell biology, ISSN 0955-0674, 12/2020, Volume 67, pp. 46 - 55
Germline stem cells | Proteostasis | RNA-binding proteins | Embryonic stem cells | Autophagy | Hematopoietic stem cells | Protein chaperones | Muscle stem cells | Cell reprogramming | Protein synthesis | Induced pluripotent stem cells | Ubiquitin proteasome system | Aging | Neural stem cells | Differentiation | Adult somatic stem cells | Index Medicus
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11. Full Text Studies from State University of New York (SUNY) Upstate Medical University Reveal New Findings on Ubiquitins (Myofibril Assembly and the Roles of the Ubiquitin Proteasome System)
12/2020
Ubiquitin | Physiological aspects | Ubiquitin-proteasome system | Reports | Research | Muscle proteins
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12. Full Text The dialogue between the ubiquitin-proteasome system and autophagy: Implications in ageing
by Sun-Wang, Jia Liang and Ivanova, Saška and Zorzano, Antonio
Ageing research reviews, ISSN 1568-1637, 12/2020, Volume 64, pp. 101203 - 101203
Proteostasis | Ubiquitin-proteasome system | UPS-autophagy crosstalk | Autophagy | Ageing | Aging | Proteasome Endopeptidase Complex - metabolism | Proteolysis | Humans | Ubiquitin - metabolism | Index Medicus
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13. Full Text The Ubiquitin/UBL Drug Target Repertoire
by Osborne, Hugh C and Irving, Elsa and Schmidt, Christine K
Trends in molecular medicine, ISSN 1471-4914, 12/2020, Volume 26, Issue 12, pp. 1133 - 1134
ubiquitin proteasome system | heterobifunctional degrader | deubiquitylating enzyme | proteasome inhibitor | ubiquitin and ubiquitin-like protein (UBL) | Index Medicus
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14. Structure, Dynamics and Function of the 26S Proteasome
by Mao, Youdong
Sub-cellular biochemistry, ISSN 0306-0225, 2021, Volume 96, pp. 1 - 151
AAA-ATPase motor | Deubiquitylation | Proteolysis | Conformational dynamics | Cryo-EM | Ubiquitylation | Homeostasis | Cryogenic electron microscopy | Ubiquitin-proteasome system | Mechanochemistry | Proteasome
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15. Full Text Regulation of Normal and Malignant Hematopoiesis by FBOX Ubiquitin E3 Ligases
by Hynes-Smith, R. Willow and Wittorf, Karli J and Buckley, Shannon M
Trends in immunology, ISSN 1471-4906, 12/2020, Volume 41, Issue 12, pp. 1128 - 1140
ubiquitin proteasome system | hematopoiesis | ubiquitin E3 ligases | FBOX proteins | Ubiquitin | Transcription factors | Anemia | Transportation services | Leukemia | Cyclin-dependent kinases | Multiple myeloma | T cell receptors | Kinases | Lymphoma | Hematopoietic stem cells | Substrates | Hemopoiesis | Proteins | Lymphocytes | Hematopoiesis | Stem cells | Cell cycle | Blood diseases | Binding sites | Apoptosis | Index Medicus
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16. Full Text Cobalt oxide nanoparticle-synergized protein degradation and phototherapy for enhanced anticancer therapeutics
by Huang, Xueqin and Cai, Huaihong and Zhou, Haibo and Li, Ting and Jin, Hua and Evans, Colin E and Cai, Jiye and Pi, Jiang
Acta biomaterialia, 11/2020
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