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Tumor Biology, ISSN 1010-4283, 10/2014, Volume 35, Issue 9, pp. 8633 - 8638
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s13277-014-2104-9... 
Cortactin | FBXL5 | Gastric cancer | Ubiquitylation
Journal Article
11/2013
DNA double-strand breaks (DSBs) are highly cytolethal DNA lesions. To protect genomic integrity and ensure cellular homeostasis, cells initiate a complex... 
DNA damage response | DNA double-strand breaks | chromatin | Molecular | ubiquitylation | Cell
Dissertation
BMB Reports, ISSN 1976-6696, 2016, Volume 49, Issue 5, p. 247
Necroptosis is a well-known form of caspase-independent cell death. Necroptosis can be triggered by various extrinsic stimuli, including death ligands in the... 
CHIP | RIPK3 | Necroptosis | Ubiquitylation | Lysosome
Journal Article
BMB Reports, ISSN 1976-6696, 2016, Volume 49, Issue 6, p. 247
Necroptosis is a well-known form of caspase-independent cell death. Necroptosis can be triggered by various extrinsic stimuli, including death ligands in the... 
CHIP | RIPK3 | Necroptosis | Ubiquitylation | Lysosome
Journal Article
Proteomics, ISSN 1615-9853, 10/2018, Volume 18, Issue 20, pp. e1800108 - e1800108
Several neurodegenerative diseases including Alzheim er’s Disease (AD) are characterized by ubiquitin-positive pathological protein aggregates. Here, an... 
proteomics | protein aggregation | neurodegeneration | mass spectrometry | post-translational modifications | ubiquitylation
Journal Article
MOLECULAR CELL, ISSN 1097-2765, 03/2013, Volume 49, Issue 5, pp. 795 - 807
Ubiquitylation and sumoylation, the covalent attachment of the polypeptides ubiquitin and SUMO, respectively, to target proteins, are pervasive mechanisms for... 
RNA-POLYMERASE-II | E3 LIGASE | HISTONE UBIQUITINATION | INDUCED UBIQUITYLATION | SELECTIVE SEGREGASE | FANCONI-ANEMIA PATHWAY | CROSS-LINK REPAIR | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | BRCA1 TUMOR SUPPRESSION | HOMOLOGOUS RECOMBINATION | CELL BIOLOGY
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 12/2018, Volume 430, Issue 24, pp. 5002 - 5014
On the nucleosome level, histone posttranslational modifications function mainly as the regulatory signals; in addition, some posttranslational modifications... 
histones | DNA topology | chromatin | ubiquitylation | nucleosomes | HISTONE H2B | CHROMATIN-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | FACT | H3 K4 | UBIQUITINATION | H2B UBIQUITYLATION | SEQUENCE | DYNAMICS | CORE PARTICLE | Ubiquitin | Chromatin | Developmental biology | Analysis | DNA | Genetic research | Histones | DNA binding proteins
Journal Article
ISSN 1474-1776, 2018
More than a decade after a Nobel Prize was awarded for the discovery of the ubiquitin-proteasome system and clinical approval of proteasome and ubiquitin E3... 
neurodegenerative diseases | cancer | drug discovery | inflammation | ubiquitylation | infectious diseases
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2010, Volume 40, Issue 1, pp. 9 - 21
PR-Set7/Set8 is a cell-cycle-regulated enzyme that monomethylates lysine 20 of histone H4 (H4K20). Set8 and monomethylated H4K20 are virtually undetectable... 
Cdt2 | Gene silencing | PR-Set7 | Set8 | Cullins | PCNA | Histone methylation | Ubiquitylation | Epigenetics
Journal Article
Methods, ISSN 1046-2023, 04/2019, Volume 159-160, pp. 146 - 156
Transcribing RNA polymerase II (RNAPII) is decorated by a plethora of post-translational modifications that mark different stages of transcription. One... 
Degradation | UV-irradiation | Ubiquitylation | RNA polymerase II | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | BIOCHEMICAL RESEARCH METHODS | DAMAGE-INDUCED UBIQUITYLATION | LARGE SUBUNIT | IDENTIFICATION | REPAIR | INDUCED UBIQUITINATION | TRANSCRIPT CLEAVAGE | CELLULAR-RESPONSE | LIGASE | Ubiquitin | RNA | Analysis | Cells
Journal Article
Epigenetics & Chromatin, ISSN 1756-8935, 08/2019, Volume 12, Issue 1, pp. 52 - 52
Maintenance of genome integrity during DNA replication is crucial to the perpetuation of all organisms. In eukaryotes, the bypass of DNA lesions by the... 
Nucleosomes | Usage | Research | Nucleotide sequencing | DNA repair | DNA sequencing | Index Medicus | SNF2 | Ubiquitination/ubiquitylation | SHPRH | Nucleosome
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2018, Volume 293, Issue 2, pp. 588 - 598
Cells have evolved sophisticated mechanisms to maintain genomic integrity in response to DNA damage. Ionizing radiation (IR)-induced DNA damage results in the... 
BINDING DOMAINS | histone modification | DNA damage response | signal transduction | DNA damage | DNA-DAMAGE RESPONSE | UBIQUITIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RNF8 | DOUBLE-STRAND BREAKS | BRCA1 | REPAIR PROTEINS | ubiquitylation (ubiquitination) | UBIQUITYLATION | ATM | HOMOLOGOUS RECOMBINATION | Index Medicus | Signal Transduction
Journal Article
Biomolecules, ISSN 2218-273X, 07/2019, Volume 9, Issue 8, p. 325
Ubiquitin (Ub) receptors respond to ubiquitylation signals. They bind ubiquitylated substrates and exert their activity in situ. Intriguingly, Ub receptors... 
Index Medicus | ubiquitylation | Ub receptor | phosphatidylinositol phosphate
Journal Article
Nature, ISSN 0028-0836, 03/2004, Volume 428, Issue 6979, pp. 190 - 193
Skp2 and its cofactor Cks1 are the substrate-targeting subunits of the SCFSkp2-Cks1 (Skp1/Cul1/F-box protein) ubiquitin ligase complex that regulates entry... 
MITOSIS | ANAPHASE-PROMOTING COMPLEX | BOX PROTEIN SKP2 | MULTIDISCIPLINARY SCIENCES | UBIQUITYLATION | DEGRADATION | CELL-CYCLE | BINDING | PROGRESSION
Journal Article
Cell Cycle, ISSN 1538-4101, 06/2010, Volume 9, Issue 12, pp. 2342 - 2352
The expression levels of the p21 Cip1 family CDK inhibitors (CKIs), p21 Cip1 , p27 Kip1 and p57 Kip2 , play a pivotal role in the precise regulation of... 
Proteins | Binding | Landes | Calcium | Biology | Bioscience | Cell | Cycle | Organogenesis | Cancer | Phosphorylation | Ubiquitylation | Proteasome | p21Cip1 | proteasome | p27Kip1 | phosphorylation | ubiquitylation | p57Kip2
Journal Article
Cancer Research, ISSN 0008-5472, 02/2019, Volume 79, Issue 4, pp. 760 - 772
Recent insights supporting the fallopian tube epithelium (FTE) and serous tubal intraepithelial carcinomas (STIC) as the tissue of origin and the precursor... 
MONOUBIQUITINATION | METHYLATION | ONCOLOGY | SEROUS CARCINOMA | TRANSCRIPTION | GENE-EXPRESSION | UBIQUITYLATION | LEADS | INTRAEPITHELIAL CARCINOMA
Journal Article
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