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Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 64, pp. 108079 - 108092
The E3 ubiquitin protein UBR5 has been implicated in the regulation of multiple biological functions and has recently emerged as a key regulator of the... 
Immunohistochemistry | Ubiquitin-proteasome system | Colorectal cancer | UBR5 | Prognostic biomarker | colorectal cancer | EDD | CISPLATIN RESISTANCE | RECEPTOR | OVARIAN-CANCER | LIGASE UBR5 | CELL BIOLOGY | ubiquitin-proteasome system | GROWTH | prognostic biomarker | TUMOR-SUPPRESSOR | THERAPIES | immunohistochemistry | PROTEASOME SYSTEM | MUTATIONS
Journal Article
Pharmazie, ISSN 0031-7144, 2017, Volume 72, Issue 7, pp. 408 - 413
UBR5 is recently recognized as a key player in a large number of prevalent cancers. In this study, we sought to explore the connection of UBR5 expression with... 
CYCLE ARREST | PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | CHEMISTRY, MULTIDISCIPLINARY | UBIQUITIN LIGASE UBR5 | GROWTH
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 40, pp. 11243 - 11248
BMI1 is a component of the Polycomb Repressive Complex 1 (PRC1), which plays a key role in maintaining epigenetic silencing during development. BMI1 also... 
Polycomb | Transcription | BMI1 | FACT | UBR5 | transcription | EDD | UBIQUITIN LIGASE | ACETYLATION | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | REPAIR | BREAKS | UBIQUITYLATION | HOMOLOGOUS RECOMBINATION | Chromatin | Genetic transcription | Health aspects | DNA damage | Biological Sciences
Journal Article
Oncogene, ISSN 0950-9232, 01/2015, Volume 34, Issue 2, pp. 154 - 164
Estrogen receptor-[alpha] (ER[alpha]) is a central transcription factor that regulates mammary gland physiology and a key driver in breast cancer. In the... 
ubiquitin ligase | high content screening | estrogen receptor | high throughput microscopy | UBR5 | Receptors | Breast cancer | Genetic aspects | Diagnosis | Analysis | Estrogen | Proteins | Ribonucleic acid--RNA | Neurons | Content analysis
Journal Article
by Pan, ZQ and Li, GF and Sun, ML and Xie, L and Liu, D and Zhang, Q and Yang, XX and Xia, SH and Liu, XD and Zhou, HM and Xue, ZY and Zhang, M and Hao, LY and Zhu, LJ and Cao, JL
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 03/2019, Volume 39, Issue 11, pp. 2125 - 2143
Dysfunctions of gene transcription and translation in the nociceptive pathways play the critical role in development and maintenance of chronic pain. Circular... 
CELLS | ABUNDANT | CIRCULAR RNAS | HYDROXYMETHYLATION | NEUROSCIENCES | chronic inflammation pain | NEUROPATHIC PAIN | circRNA-Filipi1l | GENE | spinal | NOCICEPTIVE SENSITIZATION | Ubr5 | ARGONAUTE 2 | EXPRESSION | CONTRIBUTES | miRNA-1224 | Ubiquitin | Pain perception | Transcription | Splicing | Inflammation | Gene expression | Argonaute 2 protein | Ribonucleic acid--RNA | Blockage | Proteins | Pain | Freund's adjuvant | miRNA | Mice | Ubiquitin-protein ligase
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 12/2007, Volume 6, Issue 24, pp. 3070 - 3077
The cellular response to DNA damage is critical for maintenance of genomic integrity and inhibition of tumorigenesis. Mutations or aberrant expression of the... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | CHK2 | EDD | Ubiquitin ligase | DNA damage | UBR5 | E2F1 | HECT
Journal Article
Journal Article
The Journal of Pathology, ISSN 0022-3417, 10/2013, Volume 231, Issue 2, pp. 158 - 167
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 01/2018, Volume 9, p. 80
Human T-cell leukemia virus type 1 (HTLV-1) encodes a protein derived from the antisense strand of the proviral genome designated HBZ (HTLV-1 basic leucine... 
Ubiquitin | HBZ | HTLV-1 | Proliferation | T-cell | UBR | proliferation | VIRAL TRANSCRIPTION | T-CELL LEUKEMIA | MICROBIOLOGY | TAX | ubiquitin | REPLICATION | VIRUS TYPE-I | UBR5 | GENE-EXPRESSION | RETROVIRUS | LYMPHOMA | NF-KAPPA-B | Transcription factors | Viral proteins | Ligases | Genetic aspects | T cells | Gene expression | Health aspects
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2017, Volume 292, Issue 28, pp. 11804 - 11814
MicroRNAs (miRNAs) are small, noncoding RNAs that post-transcriptionally regulate gene expression. For example, miRNAs repress gene expression by recruiting... 
post-translational modification (PTM) | RISC | CELLS | microRNA (miRNA) | EDD | HYPERPLASTIC-DISCS | UBIQUITIN LIGASE | DNA-DAMAGE RESPONSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEIN | DEUBIQUITINASE DUBA | PROTEIN-KINASES | FAMILY | E3 LIGASE | Toll-like receptor (TLR) | TRAF3 | Argonaute | UBR5 | p90RSK | phosphorylation | RNA-Binding Proteins - genetics | Phosphorylation | Autoantigens - metabolism | Humans | Cercopithecus aethiops | Ubiquitin-Protein Ligases - antagonists & inhibitors | MicroRNAs - metabolism | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | Autoantigens - genetics | Recombinant Fusion Proteins - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | RNA Interference | TNF Receptor-Associated Factor 3 - genetics | RNA, Messenger - antagonists & inhibitors | HEK293 Cells | Toll-Like Receptors - metabolism | 3' Untranslated Regions | RNA-Binding Proteins - antagonists & inhibitors | Green Fluorescent Proteins - metabolism | TNF Receptor-Associated Factor 3 - antagonists & inhibitors | Signal Transduction | Ubiquitin-Protein Ligases - metabolism | TNF Receptor-Associated Factor 3 - metabolism | Animals | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Protein Processing, Post-Translational | HeLa Cells | Mutation | Ubiquitin-Protein Ligases - genetics | COS Cells | RNA-Binding Proteins - metabolism | Amino Acid Substitution
Journal Article
Journal Article
Journal Article