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Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 2007, Volume 64, Issue 14, pp. 1853 - 1860
Uncoupling protein 2 (UCP2) belongs to a family of transporters/exchangers of the mitochon-drial inner membrane. Using cell lines representing natural sites of... 
Mitochondria | Translation | 5′untranslated region | Green fluorescent protein | UCP2 | Glutamine
Journal Article
Cardiovascular research, ISSN 0008-6363, 06/2019, Volume 115, Issue 7, pp. 1217 - 1227
Aims The role of uncoupling protein 2 ( UCP2) in cardiac adaptation to pressure overload remains unclear. In a classical model of left ventricular pressure... 
Cardiac protection | Reactive oxygen species | Cardiac remodelling | Pulmonary hypertension | Fibrosis | CARDIAC & CARDIOVASCULAR SYSTEMS | INHIBITION | UCP2 | DISEASE | RAT VENTRICULAR CARDIOMYOCYTES | EXPRESSION | Spotlight Original
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2019, Volume 510, Issue 1, pp. 48 - 52
The mechanism underlying the development of osteoarthritis induced by high tensile strain is unclear. In this study, the effects of different degrees of... 
Reactive oxygen species | Tensile strain | Chondrocyte | Cell damage | UCP2 | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXERCISE | CARTILAGE | DEGENERATION | REPAIR | BIOPHYSICS | METABOLISM | GROWTH | OSTEOARTHRITIS | MODULATION
Journal Article
Canadian Journal of Animal Science, ISSN 0008-3984, 06/2016, Volume 96, Issue 4, pp. 457 - 460
Expression of uncoupling protein (Ucp) 2 but not Ucp3 in subcutaneous fat was significantly higher in cattle fed the concentrate diet than in those fed the... 
Ucp2 | Ucp3 | Cattle (beef) | Brown/beige adipocyte | cattle (beef) | AGRICULTURE, DAIRY & ANIMAL SCIENCE | brown/beige adipocyte | GENE-EXPRESSION | UNCOUPLING PROTEIN-2
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 02/2019, Volume 845, pp. 56 - 64
Cerebral ischemia-reperfusion injury is a thorny issue in the treatment of stroke. Energy depletion and oxidative stress are the core mechanisms underlying... 
Ischemia-reperfusion injury | Mitochondria | UCP2 | Genipin | SIRT3 | CELLS | OXIDATIVE STRESS | UNCOUPLING PROTEINS | MITOCHONDRIAL-DYSFUNCTION | TIME | SIRTUINS | STROKE | METABOLISM | ANTIOXIDANT | PHARMACOLOGY & PHARMACY
Journal Article
Journal of Hypertension, ISSN 0263-6352, 07/2015, Volume 33, Issue 7, pp. 1465 - 1479
OBJECTIVES:Renal damage precedes occurrence of stroke in high-sodium/low-potassium-fed stroke-prone spontaneously hypertensive rat (SHRSP). We previously... 
PPAR-ALPHA | OXIDATIVE STRESS | high-salt diet | SPONTANEOUSLY HYPERTENSIVE-RATS | PROLIFERATOR-ACTIVATED RECEPTORS | ENDOTHELIAL FUNCTION | renal damage | BLOOD-PRESSURE | stroke-prone spontaneously hypertensive rat | Brassica oleracea | DISEASE | PERIPHERAL VASCULAR DISEASE | UNCOUPLING PROTEIN-2 | hypertension | AMPK/PGC1 alpha/SIRT1/PPAR alpha/UCP2 | BROCCOLI SPROUTS | MOLECULAR-MECHANISMS | AMP-Activated Protein Kinases - metabolism | Seedlings - chemistry | Diet - adverse effects | Proteinuria - prevention & control | Plant Extracts - administration & dosage | Proteinuria - chemically induced | Glomerular Mesangium - metabolism | Mitochondrial Proteins - metabolism | Kidney Diseases - chemically induced | Kidney Glomerulus - metabolism | Glomerular Mesangium - drug effects | Blood Pressure - physiology | Brassica - chemistry | Rats, Inbred SHR | Kidney Tubules, Proximal - pathology | Kidney Diseases - prevention & control | Kidney Glomerulus - drug effects | Sodium Chloride, Dietary - adverse effects | Rats | Antioxidants - pharmacology | Kidney Glomerulus - pathology | Glomerular Mesangium - pathology | Stroke - etiology | Animals | Ion Channels - metabolism | Iridoids - pharmacology | Kidney Tubules, Proximal - metabolism | Hypertension - complications | Uncoupling Protein 2 | Kidney Diseases - etiology | Oxidative Stress - drug effects | PPAR alpha - metabolism | Kidney Tubules, Proximal - drug effects
Journal Article
Chinese Journal of Medical Genetics, ISSN 1003-9406, 08/2018, Volume 35, Issue 4, pp. 502 - 506
Journal Article
Biochemical Society Transactions, ISSN 0300-5127, 12/2001, Volume 29, Issue 6, p. 763
Journal Article
JOURNAL OF NEUROCHEMISTRY, ISSN 0022-3042, 10/2015, Volume 135, Issue 1, pp. 147 - 156
Microglial activation is a dynamic process, central to neuroinflammation, which can have beneficial or pathogenic effects to human health. Mitochondria are key... 
CELLS | ACTIVATION | uncoupling protein-2 | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | mitochondrial membrane potential | brain macrophages | MAPK | NEUROSCIENCES | GLUCOSE | reactive oxygen species | UCP2 | ROS | cytokines | MICE | DYSFUNCTION
Journal Article
Journal of Sichuan University (Medical Science Edition), ISSN 1672-173X, 07/2018, Volume 49, Issue 4, pp. 512 - 517
Journal Article
Biochemical Society Transactions, ISSN 0300-5127, 2001, Volume 29, Issue 6, pp. 763 - 768
Addition of coenzyme Q10 (CoQ) at low concentration (29 nmol/mg of protein) to kidney but not liver mitochondria resulted in an increase in proton conductance.... 
Mitochondrion | Superoxide | UCP2
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 03/2011, Volume 50, Issue 5, pp. 609 - 616
Glucose-stimulated insulin secretion (GSIS) by pancreatic β cells is regulated by mitochondrial uncoupling protein-2 (UCP2), but opposing phenotypes, GSIS... 
Type 2 diabetes | Reactive oxygen species | Free radicals | Uncoupling protein 2 | Pancreatic β cells | Mitochondrial respiration | Glucose-stimulated insulin secretion | Coupling efficiency of oxidative phosphorylation | Metabolic syndrome | CAPACITY | Pancreatic beta cells | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTON LEAK | UCP2 | ENDOCRINOLOGY & METABOLISM | NEURONS | PANCREATIC BETA-CELLS | DYSFUNCTION | EXPRESSION | Reactive Oxygen Species - metabolism | Ion Channels - genetics | Mitochondrial Proteins - physiology | Rats | Ion Channels - physiology | Mitochondria - metabolism | Mitochondrial Proteins - genetics | Antioxidants - pharmacology | Diabetes Mellitus, Type 2 - metabolism | Metalloporphyrins - pharmacology | Gene Knockdown Techniques | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Cell Line, Tumor | Glucose - metabolism | Mice | Uncoupling Protein 2 | Energy Metabolism - physiology | Insulin Secretion | DHE, hydroethidine | FCCP, carbonyl cyanide p-trifluoromethoxyphenylhydrazone | MnTBAP, manganese tetrakis-(4-benzoic acid) porphyrin | ψ, mitochondrial membrane potential | Original Contribution | DAPI, 4′,6-diamidino-2-phenylindole | UCP2, uncoupling protein-2 | KRH, Hepes-buffered Krebs–Ringer medium | TTNPB, 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1-propenyl]benzoic acid | MnTMPyP, manganese tetrakis-(N-methyl-4-pyridyl) porphyrin | GSIS, glucose-stimulated insulin secretion | MitoSOX, mitochondria-targeted hydroethidine | ROS, reactive oxygen species | FCS, fetal calf serum
Journal Article