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Methods in molecular biology (Clifton, N.J.), 2019, Volume 1998, p. 149
Visualization of subcellular localization of ESCRT proteins and their interactions with different cellular compartments are critical to understand their... 
Journal Article
CELL, ISSN 0092-8674, 05/2014, Volume 157, Issue 5, pp. 1117 - 1129
Dynamic instability, the stochastic switching between growth and shrinkage, is essential for microtubule function. This behavior is driven by GTP hydrolysis in... 
SLOWLY HYDROLYZABLE ANALOG | ELECTRON CRYSTALLOGRAPHY | NDC80 KINETOCHORE COMPLEX | DENSITY MAPS | CRYOELECTRON MICROSCOPY | UCSF CHIMERA | BIOCHEMISTRY & MOLECULAR BIOLOGY | DYNAMIC INSTABILITY | STATHMIN-LIKE DOMAIN | BINDING | GAMMA-TUBULIN | CELL BIOLOGY
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 09/2010, Volume 17, Issue 9, pp. 1037 - 1042
The small heat shock protein alpha B-crystallin (alpha B) contributes to cellular protection against stress. For decades, high-resolution structural studies on... 
DOMAIN | X-RAY SOLUTION | UCSF CHIMERA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CRYSTALLOGRAPHY | CHAPERONE | HEAT-SHOCK-PROTEIN | CELL BIOLOGY | AMYLOID FIBRILS | BIOPHYSICS | SPECTROSCOPY | ASSEMBLIES | SOLUTION SCATTERING
Journal Article
ELIFE, ISSN 2050-084X, 12/2014, Volume 3
Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins constitute a major superfamily of pore-forming proteins that act as... 
INSERTION | PREPORE | UCSF CHIMERA | CRYSTAL-STRUCTURE | BETA-BARREL | FORMING TOXINS | BIOLOGY | ELECTRON-MICROSCOPY | PERFRINGOLYSIN-O | LIPID-MEMBRANES | BINDING
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 02/2017, Volume 33, Issue 3, pp. 444 - 446
Motivation: The recently released PyMod GUI integrates many of the individual steps required for protein sequence-structure analysis and homology modeling... 
SYSTEM | ALIGNMENT | UCSF CHIMERA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | GENERATION | BLAST | PREDICTION | FEATURES | Models, Molecular | Sequence Analysis, Protein - methods | Protein Conformation | Computational Biology - methods | Software
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 02/2014, Volume 82, Issue 2, pp. 1 - 6
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2018, Volume 61, Issue 5, pp. 1990 - 2008
Human neuraminidases (NEU) are associated with human diseases including cancer, atherosclerosis, and diabetes. To obtain small molecule inhibitors as research... 
MOLECULAR-DYNAMICS | IN-VITRO | CHEMISTRY, MEDICINAL | SWISS-MODEL WORKSPACE | UCSF CHIMERA | CRYSTAL-STRUCTURE | INFLUENZA | CYTOSOLIC SIALIDASE NEU2 | LYSOSOMAL STORAGE | DRUG ABSORPTION | SUBSTRATE RECOGNITION
Journal Article
Structure, ISSN 0969-2126, 10/2019, Volume 27, Issue 10, pp. 1547 - 1560.e4
Electron paramagnetic resonance (EPR) spectroscopy of full-length vimentin and X-ray crystallography of vimentin peptides has provided concordant structural... 
site-directed spin labeling | electron paramagnetic resonance | ESR | molecular modeling | EPR | UCSF chimera: macromolecular structure | vimentin | molecular dynamics | intermediate filaments
Journal Article
Bioinformatics, ISSN 1367-4803, 01/2018, Volume 34, Issue 2, pp. 294 - 296
Abstract Motivation Protein function is directly related to amino acid residue composition and the dynamics of these residues. Centrality analyses based on... 
VISUALIZATION | PROTEIN STRUCTURES | BIOLOGICAL NETWORKS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | UCSF-CHIMERA | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Applications Notes
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1558, pp. 111 - 124
Journal Article
Structure, ISSN 0969-2126, 2008, Volume 16, Issue 2, pp. 295 - 307
Journal Article
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 12/2018, Volume 430, Issue 24, pp. 4941 - 4954
Hepatitis B virus is a major human pathogen that consists of a viral genome surrounded by an icosahedrally ordered core protein and a polymorphic, lipidic... 
cryo electron microscopy | premature envelopment mutant | Hepatitis B virus | structure | SYSTEM | PARTICLES | UCSF CHIMERA | VIRIONS | REVERSE TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMATURE SECRETION | REPLICATION | VIRUS CAPSIDS | HIGHLY FREQUENT | MUTATION | Proteins | Genetic aspects | Gene mutations | Genomics | Hepatitis B
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 08/2017, Volume 56, Issue 34, pp. 4489 - 4499
Vitamin A (all-trans-retinol) is metabolized to the visual chromophore (11-cis-retinal), in the eyes and to. all-trans-retinoic acid, a hormone like compound,... 
VISUAL CYCLE | LEBER CONGENITAL AMAUROSIS | VITAMIN-A UPTAKE | MOLECULAR DIAGNOSIS | UCSF CHIMERA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | BINDING-PROTEIN | GENE-THERAPY | KNOCKOUT MICE | RETINITIS-PIGMENTOSA
Journal Article
Nature, ISSN 0028-0836, 08/2016, Volume 536, Issue 7617, pp. 431 - 436
In the dividing eukaryotic cell, the spindle assembly checkpoint (SAC) ensures that each daughter cell inherits an identical set of chromosomes. The SAC... 
MAD2 | ANAPHASE-PROMOTING COMPLEX | MECHANISM | CDC20 BINDING | UCSF CHIMERA | PHOSPHORYLATION | PROTEIN BUBR1 | MULTIDISCIPLINARY SCIENCES | RECOMBINANT EXPRESSION | MITOTIC CHECKPOINT | SACCHAROMYCES-CEREVISIAE | Spindle Apparatus - chemistry | Humans | Protein-Serine-Threonine Kinases - ultrastructure | Structure-Activity Relationship | Anaphase-Promoting Complex-Cyclosome - antagonists & inhibitors | Anaphase-Promoting Complex-Cyclosome - ultrastructure | Protein Subunits - metabolism | Ubiquitin-Conjugating Enzymes - chemistry | Ubiquitination | Spindle Apparatus - metabolism | Cdc20 Proteins - chemistry | Anaphase-Promoting Complex-Cyclosome - chemistry | Spindle Apparatus - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | Cdc20 Proteins - ultrastructure | Chromosome Segregation | Biocatalysis | Kinetochores - metabolism | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Ubiquitin-Conjugating Enzymes - ultrastructure | Cryoelectron Microscopy | Ubiquitin-Conjugating Enzymes - metabolism | Cdc20 Proteins - metabolism | Protein Binding | Protein Conformation | Protein Subunits - chemistry | Protein-Serine-Threonine Kinases - chemistry | Anaphase-Promoting Complex-Cyclosome - metabolism | M Phase Cell Cycle Checkpoints - physiology | Spindle (Cell division) | Physiological aspects | Research | Molecular biology | Ligases | Cell division | Kinases | Chromosomes | Binding sites | Crystal structure
Journal Article
Biochimie, ISSN 0300-9084, 02/2018, Volume 145, pp. 131 - 136
There is a critical need for better malaria rapid diagnostic tests to discriminate and infection given the recent observation of HRP2 deletions in parasites.... 
Aptamer | Diagnosis | Malaria | Plasmodium lactate dehydrogenase | TETHERED ENZYME CAPTURE | LACTATE-DEHYDROGENASE | VISUALIZATION | RECOGNITION | UCSF CHIMERA | FALCIPARUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA APTAMER | NANOPARTICLES | AMPLIFICATION | SELECTION | Plasmodium falciparum | Enzymes | Anopheles | Epidemiology
Journal Article