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Toxicology and Applied Pharmacology, ISSN 0041-008X, 2008, Volume 230, Issue 2, pp. 252 - 260
UDP glucuronosyltransferases (UGTs) play an important role for drug detoxification and toxicity. UGT function is genetically modulated by single nucleotide... 
UGT1A4 | Nuclear receptor | Xenobiotic response element | Single nucleotide polymorphism | Transcriptional regulation | UDP glucuronosyltransferase | FAMILY 1 | single nucleotide polymorphism | transcriptional regulation | GASTROINTESTINAL-TRACT | IDENTIFICATION | LOCUS | CANCER | UDP-GLUCURONOSYLTRANSFERASE-1 | POLYMORPHISMS | xenobiotic response element | nuclear receptor | PHARMACOLOGY & PHARMACY | HUMAN LIVER | TOXICOLOGY | EXPRESSION | N-GLUCURONIDATION | Liver - enzymology | Mutagenesis, Site-Directed | Humans | Receptors, Aryl Hydrocarbon - genetics | Environmental Pollutants - pharmacology | Genes, Reporter - genetics | DNA Primers | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Aryl Hydrocarbon - physiology | Xenobiotics - pharmacology | Luciferases - genetics | Genetic Variation | Glucuronosyltransferase - genetics | Mutation - drug effects | Gene Expression Regulation, Enzymologic - genetics | Polychlorinated Dibenzodioxins - pharmacology | TATA Box - genetics | Electrophoretic Mobility Shift Assay | Polymorphism, Single Nucleotide | Response Elements - genetics | Index Medicus | DIOXIN | MUTAGENS | DETOXIFICATION | MUTAGENESIS | HYDROCARBONS | TRANSCRIPTION | TOXICITY | 60 APPLIED LIFE SCIENCES | NUCLEOTIDES | ANTIDEPRESSANTS | METABOLISM | PROMOTERS | ANTICONVULSANTS | GENES | GENETIC VARIABILITY | REGULATIONS | RECEPTORS | ENVIRONMENTAL EXPOSURE | MODULATION | BLOOD
Journal Article
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 2007, Volume 35, Issue 1, pp. 116 - 120
The UGT1A3-1A5 genes are a highly related UDP-glucuronosyl-transferase (UGT) cluster exhibiting high levels of coding and regulatory region homology. However,... 
HUMAN UDP-GLUCURONOSYLTRANSFERASES | CLONING | TISSUE | GENES | PHARMACOLOGY & PHARMACY | BINDING-SITES | IDENTIFICATION | EXPRESSION | LOCUS
Journal Article
African Health Sciences, ISSN 1680-6905, 2015, Volume 15, Issue 1, pp. 146 - 149
Journal Article
Clinical Chemistry, ISSN 0009-9147, 10/2009, Volume 55, Issue 10, pp. 1770 - 1782
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0132269
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 08/2018, Volume 33, Issue 4, pp. 203 - 210
UDP-Glucuronosyltransferase (UGT) 1A enzymes catalyze the glucuronidation of various compounds. Since no correlation was observed between the protein and mRNA... 
Post-transcriptional regulation | MicroRNA | UGT | Interindividual difference | Intestine | Liver | COMPLEX | HUMAN BILIRUBIN | MICRORNAS | IDENTIFICATION | HUMAN UDP-GLUCURONOSYLTRANSFERASE | MESSENGER-RNAS | ACTIVATED-RECEPTOR-ALPHA | GENOMICS | REGIONS | PHARMACOLOGY & PHARMACY | EXPRESSION | Enzymes | Regulation | Gene expression | Health aspects | Transferases
Journal Article
Journal Article