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Synthesis, ISSN 0039-7881, 12/2010, Volume 2010, Issue 23, pp. 4107 - 4118
Abstract Multicomponent reactions (MCRs), followed by subsequent transformations, are fascinating tools for the rapid and effective synthesis of molecular... 
paper | chalcones | multicomponent reactions | isocyanides | Ugi reaction | 5-aroyl-1-aryltetrazoles | TETRAZOLES | ISONITRILE | CHEMISTRY, ORGANIC | DIVERSITY
Journal Article
ORGANIC LETTERS, ISSN 1523-7060, 10/2015, Volume 17, Issue 20, pp. 4980 - 4983
The direct macrocycle synthesis of alpha-isocyano-omega-carboxylic acids via an Ugi multicomponent reaction is introduced. This multicomponent reaction (MCR)... 
BUILDING-BLOCKS | 4-COMPONENT REACTION | CHEMISTRY, ORGANIC | CELL-PERMEABILITY | UGI REACTION | INHIBITORS | PEPTIDE | DISCOVERY | HYBRIDS
Journal Article
Green Chemistry, ISSN 1463-9262, 2014, Volume 16, Issue 6, pp. 2958 - 2975
Sustainable or green chemistry has established firm ground providing essential design criteria for the development of efficient chemical syntheses of complex,... 
Journal Article
Green Chemistry, ISSN 1463-9262, 5/2014, Volume 16, Issue 6, pp. 2958 - 2975
Journal Article
Polymer Chemistry, ISSN 1759-9954, 10/2017, Volume 8, Issue 38, pp. 5829 - 5835
We investigated intra-chain isocyanide-based multicomponent reactions to synthesize single-chain nanoparticles (SCNP) containing sequence-defined segments at... 
DESIGN | POLYMER SCIENCE | POLYMERIC NANOPARTICLES | BLOCK-COPOLYMERS | UGI 4-COMPONENT REACTION | GROWTH | CHEMISTRY | POLYAMIDES | WATER
Journal Article
Chemical science, ISSN 2041-6520, 10/2015, Volume 6, Issue 10, pp. 5446 - 5455
Aziridine aldehyde dimers, peptides, and isocyanides participate in a multicomponent reaction to yield peptide macrocycles. We have investigated the... 
Journal Article
Synthesis, ISSN 0039-7881, 04/2017, Volume 49, Issue 7, pp. 1664 - 1674
Abstract We report the synthesis of racetams, a diverse class of small molecule drugs, by means of the Ugi four-center three-component reaction (U4C-3CR). For... 
multicomponent reactions | pyrrolidones | racetams | Ugi reaction | medicinal chemistry | paper | PIRACETAM | 4-COMPONENT REACTION | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | ALCOHOLS | ACETAMIDE DERIVATIVES | MORPHOLIN-2-ONE DERIVATIVES | BETA-LACTAMS | LEVETIRACETAM
Journal Article
Organic Letters, ISSN 1523-7060, 06/2015, Volume 17, Issue 11, pp. 2606 - 2609
Herein an operationally simple multicomponent reaction of unprotected carbohydrates with amino isonitriles is presented. By the extension of this Ugi-type... 
ROUTE | UGI REACTIONS | ASYMMETRIC-SYNTHESIS | ONE-POT SYNTHESIS | 4-COMPONENT REACTION | DIRECT GLYCOSYLATION | CHEMISTRY, ORGANIC | STEREOSELECTIVE-SYNTHESIS | DERIVATIVES | ACCESS | TEMPLATES | Amino Acids - chemistry | Glycopeptides - chemistry | Glycopeptides - chemical synthesis | Molecular Structure | Carbohydrates - chemistry
Journal Article
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 8/2019, Volume 17, Issue 31, pp. 726 - 7269
This critical review focuses on some key features which determine successful enantioselective catalysed multicomponent reactions (MCRs) and are typically... 
MANNICH | HANTZSCH | 4-COMPONENT REACTION | BIGINELLI REACTION | CHEMISTRY | CHEMISTRY, ORGANIC | IONIC LIQUID | UGI REACTION | BRONSTED-ACID | MASS-SPECTROMETRY | STRUCTURAL ORGANIZATION | Transformation | Reviews | Catalysts | Reagents | Chemical bonds | Catalysis | Enantiomers | Reaction mechanisms | Intermediates
Journal Article
Chemical Communications, ISSN 1359-7345, 08/2017, Volume 53, Issue 61, pp. 8549 - 8552
Here we describe the direct usage of C,N-unprotected amino acids in Ugi-tetrazole reactions to produce a novel class of acid-tetrazole compounds. Surprisingly,... 
unclassified drug | amino acid | drug synthesis | isocyanate | reaction analysis | peptidomimetic agent | To be checked by Faculty | MULTICOMPONENT REACTIONS | ISOCYANIDE | 4-COMPONENT REACTION | DRUG DISCOVERY | CHEMISTRY | UGI REACTION | CARBOXYLIC-ACID | DERIVATIVES | UNION | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
ACS Macro Letters, ISSN 2161-1653, 11/2015, Volume 4, Issue 11, pp. 1189 - 1193
The tricomponent Biginelli reaction and the tetracomponent Hantzsch reaction which share the same reaction modules (aldehyde and β-ketone ester) have been... 
FUNCTIONAL POLYMERS | POLYMER SCIENCE | KABACHNIK-FIELDS REACTION | MULTIFUNCTIONAL POLYMERS | UGI 4-COMPONENT REACTION | PASSERINI 3-COMPONENT REACTION | EPOXY CLICK CHEMISTRY | POLYMERIZATION
Journal Article
European Polymer Journal, ISSN 0014-3057, 07/2018, Volume 104, pp. 32 - 38
Sequence-defined and information coding macromolecules suitable for data storage materials were synthesized a combination of two multicomponent reactions.... 
Sequence-definition | Multicomponent reactions | Digital polymers | Mass spectrometry | Macromolecules | Data storage | ENCODED OLIGOMERS | POLYMER SCIENCE | DESIGN | UGI 4-COMPONENT REACTION | LIBRARIES | DNA | CHEMISTRY | GENERATION | Oligomers | Computer storage devices
Journal Article
RSC Advances, ISSN 2046-2069, 2014, Volume 4, Issue 72, pp. 38159 - 38163
A facile and efficient synthetic method for the stereoselective preparation of trisubstituted tetrahydro-beta-carboline-fused diketopiperazine derivatives is... 
MULTICOMPONENT REACTIONS | PICTET-SPENGLER REACTION | UGI 4-COMPONENT REACTION | DRUG DISCOVERY | CHEMISTRY | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Topics in Current Chemistry, ISSN 2365-0869, 8/2017, Volume 375, Issue 4, pp. 1 - 29
Journal Article
Tetrahedron, ISSN 0040-4020, 09/2017, Volume 73, Issue 39, pp. 5778 - 5783
A new category of bis- and tris-amides was synthesized using succinic acid, succinic anhydride and maleic anhydride in the Ugi reaction. It provides a simple... 
Bis-amide, tris-amides | Micheal addition | Succinic anhydride | Succinic acid | Ugi adducts | Multi-component reaction | Maleic anhydride | ONE-POT | 4-COMPONENT REACTION | CHEMISTRY, ORGANIC | AZIDE | MULTICOMPONENT REACTIONS | PEPTIDOMIMETICS | HETEROCYCLES | 2,5-DIKETOPIPERAZINES | PRODUCTS | CHEMISTRY | DIVERSITY | Amides
Journal Article
Chemical Science, ISSN 2041-6520, 07/2015, Volume 6, Issue 10, pp. 5446 - 5455
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2016, Volume 138, Issue 27, pp. 8612 - 8622
Journal Article
Tetrahedron, ISSN 0040-4020, 10/2014, Volume 70, Issue 43, pp. 7996 - 8003
A facile one-pot synthesis of functionalized 1,2-dihydrobenzo[ ][1,6]naphthyridines is described via sequential Ugi four components using... 
One-pot | Heck reaction | Functionalized | Ugi reaction | Benzo[b][1,6]naphthyridines | BICYCLIC LACTAMS | TANDEM SYNTHESIS | 3-COMPONENT REACTION | NAPHTHYRIDINES | 4-COMPONENT REACTION | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | CYTOTOXIC ACTIVITY | DIVERSE ROUTE | MULTICOMPONENT REACTIONS | FACILE SYNTHESIS | Organic acids
Journal Article