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ANNALS OF INTERNAL MEDICINE, ISSN 0003-4819, 06/2010, Volume 152, Issue 12, pp. 761 - 761
Background: Cytomegalovirus (CMV) is the most prevalent opportunistic infection after lung transplantation. Current strategies do not prevent CMV in most... 
ORAL GANCICLOVIR | BRONCHIOLITIS OBLITERANS | TRIAL | MEDICINE, GENERAL & INTERNAL | GANCICLOVIR RESISTANCE | UL97 MUTATIONS | REJECTION | DISEASE | CMV INFECTION | RECIPIENTS | EMERGENCE
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 09/2019, Volume 63, Issue 9
Mutations in the cytomegalovirus UL97 kinase gene contribute to anti-viral resistance. Mutations A594S and G598D from two clinical isolates were analyzed, and... 
mutation | PROPHYLAXIS | UL97 | cytomegalovirus | PROTEIN-KINASE | RESISTANCE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | drug resistance | ganciclovir | phosphorylation | protein kinase
Journal Article
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, ISSN 0305-7453, 08/2019, Volume 74, Issue 8, pp. 2370 - 2376
Objectives: Antiviral resistance in cytomegalovirus (CMV) may result from mutations in the molecular targets of antiviral agents. The aim of this study was to... 
INFECTIOUS DISEASES | RISK-FACTORS | KINASE | MICROBIOLOGY | DRUG-RESISTANCE | RECIPIENTS | EMERGENCE | UL97 | DISEASE | PHARMACOLOGY & PHARMACY | MUTATIONS | OUTCOMES | VALGANCICLOVIR
Journal Article
Future Virology, ISSN 1746-0794, 01/2017, Volume 12, Issue 1, pp. 13 - 18
Aim: Human cytomegalovirus (HCMV) treatment is hard to achieve because of viral protein target sequence variations. Objectives: We aimed to find HCMV pUL97... 
HIV | UL97 substitution | HCMV | cCMV | UL97 D605E MUTATION | GANCICLOVIR RESISTANCE | PREVALENCE | RECIPIENTS | EMERGENCE | THERAPY | VIROLOGY | DISEASE | GENES | STEM-CELL TRANSPLANTATION
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 10/2019, Volume 63, Issue 10
To determine the mechanism of action of third-generation methylenecyclopropane nucleoside analogs (MCPNAs), DNA sequencing of herpes simplex virus 1 (HSV-1)... 
CYTOMEGALOVIRUS UL97 MUTATIONS | MECHANISM | PHOSPHORYLATION | KINASE | MICROBIOLOGY | viral DNA polymerase | human cytomegalovirus | herpes simplex virus | CYCLOPROPAVIR | METABOLISM | antiviral | GANCICLOVIR | RESISTANCE | ANTIVIRAL ACTIVITY | PHARMACOLOGY & PHARMACY | PARADIGM
Journal Article
Antiviral Research, ISSN 0166-3542, 09/2018, Volume 157, pp. 128 - 133
The human cytomegalovirus (CMV) UL97 kinase inhibitor maribavir is in Phase III clinical trials as antiviral therapy, including use for infections refractory... 
Maribavir | Cytomegalovirus | Ganciclovir | Antagonism | Sirolimus | Synergism | RESISTANT CYTOMEGALOVIRUS | UL97 KINASE | ORAL MARIBAVIR | VIRAL-INFECTION | IN-VITRO | INHIBITION | REPLICATION | VIROLOGY | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | MUTATIONS | Analysis | Communicable diseases | Cytomegalovirus infections | Rapamycin | Drug resistance | Drug therapy | Health aspects | synergism | ganciclovir | antagonism | maribavir | sirolimus
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 04/2019, Volume 294, Issue 15, pp. 6188 - 6203
Journal Article
Journal Article