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unsymmetrical ureas (64) 64
chemistry, organic (59) 59
derivatives (42) 42
chemistry, multidisciplinary (35) 35
amines (30) 30
urea (22) 22
ureas (21) 21
inhibitors (20) 20
synthesis (18) 18
chemistry (15) 15
isocyanates (14) 14
one-pot synthesis (14) 14
carbonylation (13) 13
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unsymmetrical urea (13) 13
chemistry, medicinal (12) 12
catalysis (11) 11
index medicus (11) 11
microwave irradiation (10) 10
chemical synthesis (9) 9
chemistry, inorganic & nuclear (9) 9
chiral unsymmetrical urea (9) 9
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urea - analogs & derivatives (9) 9
urea - chemical synthesis (9) 9
urea - chemistry (9) 9
carbon-monoxide (8) 8
chemistry, physical (8) 8
design (8) 8
efficient synthesis (8) 8
mild conditions (8) 8
recognition (8) 8
reductive carbonylation (8) 8
selenium (8) 8
tetrasubstituted ureas (8) 8
curtius rearrangement (7) 7
isocyanate (7) 7
oxidative carbonylation (7) 7
practical synthesis (7) 7
discovery (6) 6
efficient (6) 6
potent (6) 6
primary amines (6) 6
solid-phase synthesis (6) 6
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carbamates (5) 5
carbon-dioxide (5) 5
hydroxamic acids (5) 5
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nitrobenzene (5) 5
organic-synthesis (5) 5
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protease inhibitors (5) 5
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unsymmetrical (5) 5
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agents (4) 4
amides (4) 4
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biochemistry & molecular biology (4) 4
carbon monoxide (4) 4
carbonyls (4) 4
catalyzed oxidative carbonylation (4) 4
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coumarin (4) 4
harnstoff (4) 4
one-pot (4) 4
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s,s-dimethyl dithiocarbonate (4) 4
thiourea (4) 4
thioureas (4) 4
water (4) 4
1,3,4-thiadiazoles (3) 3
1,3-disubstituted ureas (3) 3
acid (3) 3
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amine (3) 3
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Reactive and Functional Polymers, ISSN 1381-5148, 03/2018, Volume 124, pp. 156 - 161
Model compounds of unsymmetrical -ureas have been designed and synthesised to investigate and further understand the formation of supramolecular polymer... 
Bis-urea | Association constant | Unsymmetrical | Self-assembly | Hydrogen bonding | GELATORS | DESIGN | POLYMER SCIENCE | GELS | LOW-MOLECULAR-MASS | SUPRAMOLECULAR POLYMERS | GELATION | ELASTOMERS | ENGINEERING, CHEMICAL | ORGANIC-SOLVENTS | CHEMISTRY | CHEMISTRY, APPLIED | URETHANE | Drugstores | Urea | Nuclear magnetic resonance spectroscopy | Hydrogen | Pharmacy | Analysis
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2017, Volume 139, Issue 43, pp. 15407 - 15413
Organic isocyanates are versatile intermediates that provide access to a wide range of functionalities. In this work, we have developed the first synthetic... 
SOLUBLE EPOXIDE HYDROLASE | HYDROXAMIC ACIDS | SPECTROSCOPY | EPR | BONDS | SALEN | CONFORMATION | FLUORINATION | UNSYMMETRICAL UREAS | CHEMISTRY, MULTIDISCIPLINARY | LATE-STAGE FUNCTIONALIZATION
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 08/2018, Volume 360, Issue 15, pp. 2820 - 2824
A palladium‐catalyzed carbonylative procedure for the synthesis of unsymmetrical ureas has been developed. This one‐pot one‐step cascade procedure is consisted... 
Cascade reaction | Curtius rearrangement | Carbonylation | Palladium catalyst | Unsymmetrical urea | OXIDATIVE CARBONYLATION | ASYMMETRIC CATALYSIS | SMALL-MOLECULE | ONE-POT | CHEMISTRY, ORGANIC | REDUCTIVE CARBONYLATION | SELENIUM | AROMATIC AZIDOCARBONYLATION | AMINES | CHEMISTRY, APPLIED | DERIVATIVES | Palladium catalysts | Urea | Palladium | Amines | Iodides | Aromatic compounds | Ureas | Chemical synthesis | Carbonyls
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 05/2014, Volume 79, Issue 10, pp. 4477 - 4483
A practical one-pot synthesis of ureas is described. Boc-protected amines can be transformed into nonsymmetrical and symmetrical disubstituted and... 
THIOUREAS | FACILE SYNTHESIS | ACID | CARBONYLATION | CONVERSION | CHEMISTRY, ORGANIC | SOLID-PHASE SYNTHESES | CLEAVAGE | UNSYMMETRICAL UREAS | EFFICIENT | DERIVATIVES | Amines - chemistry | Pyridines - chemistry | Urea - analogs & derivatives | Molecular Structure | Mesylates - chemistry | Urea - chemical synthesis | Urea - chemistry
Journal Article
Green Chemistry, ISSN 1463-9262, 2016, Volume 18, Issue 24, pp. 6630 - 6636
A novel solvent- and halide-free atom-economical synthesis of practically useful pyridine-2-yl substituted ureas utilizes easily accessible or commercially... 
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2018, Volume 59, Issue 17, pp. 1614 - 1618
An efficient approach to N, N′-unsymmetrically substituted ureas has been developed through the ammonolysis process of -Boc protected anilines with amines... 
Ureas | Organocatalyzed | DABCO | TBD | Ammonolysis | BOC-PROTECTED AMINES | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | DISCOVERY | INDOLES | SUBSTITUTED UREAS | CATALYZED OXIDATIVE CARBONYLATION | UNSYMMETRICAL TETRASUBSTITUTED UREAS | ISOCYANATES | INHIBITORS | DERIVATIVES
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 07/2018, Volume 54, Issue 60, pp. 8363 - 8366
Insertion of isocyanides into the N-H bond gives access to many medicinally important and structurally diverse complex nitrogen-containing heterocycles.... 
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 60, pp. 8363 - 8366
Insertion of isocyanides into the N-H bond gives access to many medicinally important and structurally diverse complex nitrogen-containing heterocycles.... 
SYSTEM | CARBONYLATION | ONE-POT SYNTHESIS | AMINES | GREENER CONDITIONS | POLYMERIZATION | INHIBITORS | ANTAGONISTS | UNSYMMETRICAL UREAS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Isocyanates | Synthesis | Amines | Hydrogen bonds | Reagents | Insertion | Ureas | Nitrogen | Aliphatic compounds | Substrates | Iodine | Aliphatic amines
Journal Article
by Kang, S and Kim, HK
TETRAHEDRON, ISSN 0040-4020, 07/2018, Volume 74, Issue 30, pp. 4036 - 4046
A practical synthetic method for the direct synthesis of unsymmetrically substituted ureas from N-Alloc-, N-Cbz-, and N-Boc-protected amines is described. In... 
HIV-1 PROTEASE INHIBITORS | RECEPTOR ANTAGONISTS | ONE-POT SYNTHESIS | ANALOGS | ALME3 | DABAL-Me-3 | CHEMISTRY, ORGANIC | Unsymmetrical ureas | DISCOVERY | Urea synthesis | CARBONYLATION | DHMEQ | Protected carbamates | DERIVATIVES | AMIDES
Journal Article
Organic Letters, ISSN 1523-7060, 01/2016, Volume 18, Issue 2, pp. 212 - 215
An unprecedented protocol for urea synthesis directly from methanol and amine was accomplished. The reaction is highly atom-economical, producing hydrogen as... 
DEHYDROGENATIVE OXIDATION | PRACTICAL SYNTHESIS | MILD CONDITIONS | BIPYRIDONATE LIGAND | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | N-FORMYLATION | CYCLIC CARBONATES | UNSYMMETRICAL UREAS | DIRECT AMIDE SYNTHESIS | SUBSTITUTED UREAS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 06/2012, Volume 53, Issue 23, pp. 2890 - 2893
Bromodimethylsulfonium bromide (BDMS) was found to be a very efficient reagent for Lossen rearrangement of hydroxamic acids to the corresponding isocyanates... 
Isocyanates | Bromodimethylsulfonium bromide (BDMS) | Lossen rearrangement | Hydroxamic acids | Unsymmetrical ureas | REAGENT | ONE-POT SYNTHESIS | ACIDS | CHEMISTRY, ORGANIC | AMINES | (BROMODIMETHYL)SULFONIUM BROMIDE | CHEMISTRY | INHIBITORS | DERIVATIVES
Journal Article
Synthesis, ISSN 0039-7881, 05/2017, Volume 49, Issue 10, pp. 2163 - 2176
Abstract A wide range of chemicals such as amides, hydrazides, amines, alcohols, carbazate, and sulfonate were reacted with acyl isocyanates generated by the... 
paper | acyl isocyanates | acyl carbamates | acyl ureas | acyl thiocarbamates | bioisostere | symmetrical/unsymmetrical diacyl ureas | ACYLATION | OXALYL CHLORIDE | DRUG DESIGN | CHEMISTRY, ORGANIC | AROYL ISOTHIOCYANATES | PHOSGENE | CARBON-MONOXIDE | AMINES | CHEMISTRY | ISOCYANATES | AMIDES
Journal Article
MOLECULES, ISSN 1420-3049, 10/2017, Volume 22, Issue 10
Positron emission tomography is an imaging technique with applications in clinical settings as well as in basic research for the study of biological processes.... 
CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEDIATED SYNTHESIS | carbon monoxide | UNSYMMETRICAL UREAS | CHEMISTRY, MULTIDISCIPLINARY | urea | PRESSURE | C-11-labelling | POSITRON-EMISSION-TOMOGRAPHY | RADIOSYNTHESIS | PALLADIUM-CATALYZED CARBONYLATION | carbon-11 | CARBAMOYL CHLORIDES | INHIBITORS | positron emission tomography | carbonylation | EFFICIENT
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 10/2019, Volume 2019, Issue 37, pp. 6359 - 6368
A palladium‐catalyzed domino method for the direct synthesis of carbamates and ureas has been developed by using readily available and economical starting... 
Carbamates | Heterogeneous catalysis | Domino reactions | Curtius rearrangement | Carbonylation | Unsymmetrical ureas | Palladium | Magnetite
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 02/2013, Volume 54, Issue 8, pp. 975 - 979
A simple, mild, and an alternative protocol for the preparation of , ′-disubstituted ureas from readily available ethers and cyanamides as starting materials... 
Lewis acid | N,N′-disubstituted ureas | Ethers | Cyanamides | OXIDATIVE CARBONYLATION | CATALYZED SYNTHESIS | ONE-POT | DIOXIDE | CHEMISTRY, ORGANIC | CARBON-CARBON BONDS | N,N '-disubstituted ureas | REDUCTIVE CARBONYLATION | UNSYMMETRICAL UREAS | OXYGEN | AMINES | INHIBITORS
Journal Article
by Tran, VH and Kim, HK
NEW JOURNAL OF CHEMISTRY, ISSN 1144-0546, 09/2019, Volume 43, Issue 35, pp. 14093 - 14101
A novel and facile CaI2-catalyzed direct synthesis of asymmetrical ureas from N-Alloc-, N-Troc-, and N-Cbz-protected amines is developed. In this study, the... 
SAR | MODULATORS | RECEPTOR | INHIBITORS | UNSYMMETRICAL UREAS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY
Journal Article
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