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life sciences & biomedicine (15) 15
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Clinical cancer research, ISSN 1557-3265, 11/2016, Volume 22, Issue 22, pp. 5487 - 5496
Journal Article
The Lancet (British edition), ISSN 0140-6736, 05/2012, Volume 379, Issue 9829, pp. 1893 - 1901
.... We aimed to assess its safety and tolerability and to establish a recommended phase 2 dose in patients with incurable solid tumours, especially those with melanoma and untreated, asymptomatic brain metastases... 
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Oximes - adverse effects | Humans | Middle Aged | Carcinoma, Squamous Cell - chemically induced | Oximes - administration & dosage | Imidazoles - administration & dosage | Male | Fatigue - chemically induced | Antineoplastic Agents - administration & dosage | Fever - chemically induced | Indoles - administration & dosage | Brain Neoplasms - secondary | Neoplasms - genetics | Antineoplastic Agents - adverse effects | Melanoma - genetics | Adult | Female | Drug Administration Schedule | Imidazoles - adverse effects | Genotype | Treatment Outcome | Skin Neoplasms - chemically induced | Brain Neoplasms - drug therapy | Mutation - genetics | Melanoma - secondary | Neoplasms - drug therapy | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Maximum Tolerated Dose | Indoles - adverse effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Sulfonamides - adverse effects | Sulfonamides - administration & dosage | Antimitotic agents | Complications and side effects | Melanoma | Dosage and administration | Metastasis | Antineoplastic agents | Drug therapy | Clinical trials | Medical research | Chemotherapy | Mutation | Toxicity | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Value in health, ISSN 1098-3015, 07/2019, Volume 22, Issue 7, pp. 777 - 784
.... To understand how consideration of option value may affect the potential cost-effectiveness of a treatment through a case study of ipilimumab for previously untreated metastatic melanoma... 
cost-effectiveness | option value | life extension | Economics | Social Sciences | Life Sciences & Biomedicine | Health Care Sciences & Services | Business & Economics | Health Policy & Services | Science & Technology | Drug Costs | Markov Chains | Skin Neoplasms - drug therapy | Humans | Middle Aged | Male | Models, Economic | Skin Neoplasms - economics | Clinical Trials, Phase III as Topic | Time Factors | Life Expectancy | Skin Neoplasms - mortality | Clinical Decision-Making | Ipilimumab - economics | Ipilimumab - therapeutic use | Female | Quality-Adjusted Life Years | Skin Neoplasms - pathology | Ipilimumab - adverse effects | Disease Progression | Melanoma - secondary | Antineoplastic Agents, Immunological - economics | Antineoplastic Agents, Immunological - adverse effects | Antineoplastic Agents, Immunological - therapeutic use | Cost-Benefit Analysis | Melanoma - drug therapy | Progression-Free Survival | Melanoma - economics | Quality of Life | Melanoma - mortality | Medical technology | Effectiveness | Medical treatment | Mortality | Innovations | Melanoma | Clinical trials | Clinical research | Efficacy | Metastasis | Epidemiology | Metastases | Untreated | Surveillance | Skin melanoma | Value | Approaches | Timing | Cost analysis | Quality adjusted life years | Cancer | Index Medicus
Journal Article
Journal Article
Value in health, ISSN 1098-3015, 10/2017, Volume 20, Issue 9, p. A423
OBJECTIVES: Metastatic melanoma is one of the most aggressive forms of cancer, affecting over 150,000 new patients annually worldwide... 
Drugs | Health insurance | Oncologists | Social insurance | Parameters | Medical treatment | Melanoma | Combination therapy | Patients | Uptake | Market shares | Impact analysis | Metastases | Studies | Prices | Untreated | Health care expenditures | Skin melanoma | Treatment methods | Models | Mutation | Malignant | Cancer
Journal Article
International journal of ophthalmology, ISSN 2222-3959, 2014, Volume 7, Issue 4, pp. 697 - 703
...(SLO) imaging for differentiating choroidal pigmented lesions.·METHODS: A consecutive series of 139 patients were included, 101 had established choroidal melanoma with13 untreated lesions and 98 treated... 
untreated | fundus | screening | appearance | choroidal | melanoma | pigmented | standardized | longitudinal | diameters | Life Sciences & Biomedicine | Ophthalmology | Science & Technology | choroidal lesion | autofluorescence | imaging | scanning laser ophthalmoscopy
Journal Article