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Rheumatology (United Kingdom), ISSN 1462-0324, 04/2017, Volume 56, Issue 4, pp. 654 - 659
Journal Article
EUROPEAN RESPIRATORY JOURNAL, ISSN 0903-1936, 06/2019, Volume 53, Issue 6
Our systematic analysis of anion channels and transporters in idiopathic pulmonary arterial hypertension (IPAH) showed marked upregulation of the Cl- channel... 
BENZBROMARONE | ENTRY | ACTIVATED CHLORIDE CHANNEL | URAT1 | RESPIRATORY SYSTEM | SMOOTH-MUSCLE-CELLS | UP-REGULATION | CONTRIBUTES | EXPRESSION
Journal Article
Phytomedicine, ISSN 0944-7113, 09/2019, Volume 62, p. 152975
Background: Alpinia oxyphylla is a well-known traditional medicine used in China and Korea to treat intestinal disorders, urosis, diuresis, and chronic... 
Uric acid excretion | Hyperuricemia | Potassium oxonate-induced hyperuricemic rat | Organic anion transporter 1 (OAT1) | Alpinia oxyphylla Miquel | Urate transporter 1 (URAT1)
Journal Article
Expert Opinion on Therapeutic Patents, ISSN 1354-3776, 11/2019, Volume 29, Issue 11, pp. 871 - 879
Introduction: Human urate transporter 1 (URAT1), which is an influx transporter protein, is located at the apical surface of renal tubular cells and presumed... 
hyperuricemia | benzbromarone | SHR4640 | sulfonamide | RDEA3170 | gout | dual inhibitor | lesinurad | URAT1 inhibitors
Journal Article
PEDIATRIC NEPHROLOGY, ISSN 0931-041X, 12/2018, Volume 33, Issue 12, pp. 2275 - 2275
Journal Article
Chinese Journal of New Drugs, ISSN 1003-3734, 09/2016, Volume 25, Issue 18, pp. 2129 - 2135
Journal Article
Journal Article
Chinese Journal of Organic Chemistry, ISSN 0253-2786, 07/2017, Volume 37, Issue 7, pp. 1748 - 1756
Journal Article
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 04/2019, Volume 34, Issue 2, pp. 155 - 158
The inhibitor of uric acid reabsorptive transporter URAT1 in kidney is drawing attention as a drug target for hyperuricemia. However, it is difficult to... 
Animal model | Uric acid | Xenobiotic marker | URAT1 | Analogue | Kidney | OXYPURINOL | CONCOMITANT TREATMENT | PHARMACOLOGY & PHARMACY | URICOSURIC AGENTS
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 03/2018, Volume 214, pp. 29 - 36
Dioscin, a spirostane glycoside, the rhizoma of (Diocoreacea) is used for diuresis, rheumatism, and joints pain. Given the poor solubility and stability of... 
Dioscin | Uric acid excretion | Hyperuricemia | URAT1 | Tigogenin | ABCG2 | HOMEOSTASIS | METABOLITES | CHEMISTRY, MEDICINAL | TRANSPORTER | PREVALENCE | DISCOVERY | PLANT SCIENCES | ALLOPURINOL | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY | CHRONIC KIDNEY-DISEASE
Journal Article