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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 09/2019, Volume 20, Issue 18, p. 4503
There is robust evidence indicating that enhancing the endocannabinoid (eCB) tone has therapeutic potential in several brain disorders. The inhibition of eCBs... 
URB597 | TARGET | SELECTIVE FAAH INHIBITOR | patients' compliance | DRUG-DELIVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCANNABINOID SYSTEM | endocannabinoid tone | CHEMISTRY, MULTIDISCIPLINARY | PF-04457845 | STRATEGIES | NEUROPATHIC PAIN | fatty acid amide hydrolase | intranasal drug delivery | BRAIN | CANNABINOIDS | patients’ compliance
Journal Article
Progress in Neuropsychopharmacology & Biological Psychiatry, ISSN 0278-5846, 03/2019, Volume 90, pp. 84 - 91
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2019, Volume 299, pp. 52 - 58
Hypertension is a civilization disease leading to remodeling and damage of blood vessels, impaired renal function and premature death. The aim of this study... 
Hypertension | URB597 | Membrane composition | Electrical properties | Kidney | OXIDATIVE STRESS | ACID | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANANDAMIDE | PLASMA-MEMBRANE | METABOLISM | CARDIOVASCULAR FUNCTION | PURIFICATION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | RECEPTORS | CANNABINOIDS
Journal Article
Chemistry and Physics of Lipids, ISSN 0009-3084, 01/2019, Volume 218, pp. 141 - 148
Pressure overload, which is typical of hypertension, is known to evoke alterations not only in the morphology of the heart but also in the preference of... 
URB597 | Hypertension | Fatty acid transporters | Spontaneously hypertensive rats | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBSTRATE METABOLISM | FAT/CD36 | HEART | HYPERTROPHY | TRANSPORT | BIOPHYSICS | REDISTRIBUTION | INCREASE | IN-VIVO | HEALTH | Heart | Enzymes | Liquefied gases | Physiological aspects | Hydrolases | Liquid chromatography | Fatty acids
Journal Article
Psychopharmacology, ISSN 0033-3158, 8/2015, Volume 232, Issue 15, pp. 2811 - 2825
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 12/2018, Volume 367, Issue 3, pp. 551 - 563
Opioid-based therapies remain a mainstay for chronic pain management, but unwanted side effects limit therapeutic use. We compared efficacies of brain-permeant... 
CANNABINOID RECEPTORS | URB597 | FAAH | CB1 | MONOACYLGLYCEROL LIPASE | PAIN MODELS | BEHAVIOR | PERIPHERAL NEUROPATHY | DELTA-TETRAHYDROCANNABINOL | PHARMACOLOGY & PHARMACY | RAT MODEL
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 11/2019, Volume 392, Issue 11, pp. 1393 - 1400
Journal Article
Psychopharmacology, ISSN 0033-3158, 09/2009, Volume 205, Issue 4, pp. 613 - 624
The endocannabinoid system has been recently identified as having critical involvement in drug taking and relapse phenomenon for various drugs of abuse and... 
Self-administration | FAAH | Relapse | receptor | Motivation | Nicotine | DRUG | PPAR-ALPHA | CONDITIONED PLACE PREFERENCES | ANANDAMIDE HYDROLYSIS | PSYCHIATRY | FAAH INHIBITION | NEUROSCIENCES | NUCLEUS-ACCUMBENS | ESTER URB597 | PROGRESSIVE RATIO SCHEDULES | CB1 receptor | DOPAMINE LEVELS | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | Smoking cessation | Antagonist drugs | Psychopharmacology | Rodents
Journal Article