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Journal Article
Journal Article
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 4/2014, Volume 27, Issue 4, pp. 586 - 595
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, pp. e0125285 - e0125285
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2018, Volume 367, Issue 3, pp. 452 - 460
In chronic kidney disease (CKD), the gut microbiome is altered and bacterial-derived uremic toxins promote systemic inflammation and cardiovascular disease.... 
SYSTEMIC INFLAMMATION | INTESTINAL INFLAMMATION | TRIMETHYLAMINE-N-OXIDE | OXIDATIVE STRESS | UREMIC TOXINS | SIZED POLYETHYLENE-GLYCOLS | AKKERMANSIA-MUCINIPHILA | CARDIOVASCULAR-DISEASE | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | IRON
Journal Article
Journal Article
by Chang, JR and Guo, J and Wang, Y and Hou, YL and Lu, WW and Zhang, JS and Yu, YR and Xu, MJ and Liu, XY and Wang, XJ and Guan, YF and Zhu, Y and Du, J and Tang, CS and Qi, YF
KIDNEY INTERNATIONAL, ISSN 0085-2538, 03/2016, Volume 89, Issue 3, pp. 586 - 600
Deficiency in alpha-Klotho is involved in the pathogenesis of vascular calcification. Since intermedin (IMD)(1-53) (a calcitonin/calcitonin gene-related... 
chronic kidney disease | ISCHEMIA/REPERFUSION INJURY | PROTEIN | vascular calcification | UREMIC RATS | RECEPTOR | VENTRICULAR MYOCYTES | intermedin(1-53) | TRANSCRIPTS ENCODING MEMBRANE | calcitonin receptor-like receptor | VITAMIN-D ANALOGS | ARTERIAL STIFFNESS | GROWTH-FACTOR 23 | UROLOGY & NEPHROLOGY | alpha-Klotho | SMOOTH-MUSCLE-CELLS
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 07/2019, Volume 234, Issue 7, pp. 11882 - 11887
Objective This study aimed to explore the underlying function of Gubenxiezhuo dialysis on the distribution of gut microflora uremia. Methods A uremia rat model... 
inflammation, uremic | gut microbiota | gubenxiezhuo dialysis | uremic | PHYSIOLOGY | ACID | INTESTINAL MICROBIOTA | TOXINS | PROTECTS | CELL BIOLOGY | RED | inflammation | DISEASE | EXTRACT | Animal experimentation | Enzymes | Kidney diseases | Microbiota (Symbiotic organisms) | Escherichia coli | Enzyme-linked immunosorbent assay
Journal Article
Journal of Hypertension, ISSN 0263-6352, 02/2017, Volume 35, Issue 2, pp. 376 - 384
OBJECTIVE:Arterial stiffness and calcification are nontraditional cardiovascular risk factors in chronic kidney disease (CKD). Using a rat model of CKD with... 
Endothelin | Inflammatory cytokines | Arterial stiffness | S100A8/S100A9 | Vascular calcification | Chronic kidney disease | Atrasentan | Endothelin type A receptor | arterial stiffness | ERYTHROPOIETIN-INDUCED HYPERTENSION | chronic kidney disease | vascular calcification | UREMIC RATS | NECROSIS-FACTOR-ALPHA | inflammatory cytokines | AORTIC STIFFNESS | BLOOD-PRESSURE | endothelin | endothelin type A receptor | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | STAGE RENAL-DISEASE | CARDIOVASCULAR RISK | atrasentan | GLYCATION END-PRODUCTS | Tumor Necrosis Factor-alpha - metabolism | Calgranulin B - metabolism | Pulse Wave Analysis | Rats, Wistar | Calgranulin A - metabolism | Calcium - administration & dosage | Male | Renal Insufficiency, Chronic - complications | Macrophages | Pyrrolidines - pharmacology | Inflammation - complications | Interleukin-1beta - metabolism | Phosphorus, Dietary - administration & dosage | Vascular Calcification - complications | Vascular Calcification - physiopathology | Vitamin D - administration & dosage | Blood Pressure - drug effects | Vascular Stiffness | Interleukin-6 - metabolism | Aorta, Thoracic - pathology | Biomarkers - metabolism | Endothelin A Receptor Antagonists - pharmacology | Endothelin-1 - metabolism | Aorta, Thoracic - metabolism | Rats | Vascular Calcification - prevention & control | Receptor, Endothelin A - drug effects | Renal Insufficiency, Chronic - physiopathology | Animals | Inflammation - prevention & control | Inflammation - physiopathology
Journal Article