Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
usp9x (89) 89
index medicus (54) 54
humans (49) 49
apoptosis (33) 33
ubiquitin thiolesterase - metabolism (30) 30
animals (28) 28
cell biology (27) 27
ubiquitination (27) 27
ubiquitin (26) 26
oncology (25) 25
cancer (20) 20
expression (20) 20
mice (19) 19
ubiquitin thiolesterase - genetics (19) 19
cell line, tumor (18) 18
female (17) 17
genetic aspects (16) 16
proteins (16) 16
article (15) 15
biochemistry & molecular biology (15) 15
signal transduction (15) 15
analysis (11) 11
degradation (11) 11
male (11) 11
research (11) 11
endopeptidases - metabolism (10) 10
inhibition (10) 10
protein (10) 10
research paper (10) 10
apoptosis - drug effects (9) 9
beta-catenin (9) 9
deubiquitination (9) 9
enzymes (9) 9
hek293 cells (9) 9
metastasis (9) 9
physiological aspects (9) 9
survival (9) 9
breast cancer (8) 8
cell proliferation (8) 8
deubiquitinating enzyme (8) 8
down-regulation (8) 8
fam/usp9x (8) 8
gene (8) 8
genetics & heredity (8) 8
mcl-1 (8) 8
multidisciplinary sciences (8) 8
mutation (8) 8
proliferation (8) 8
resistance (8) 8
ubiquitin-protein ligases - metabolism (8) 8
activation (7) 7
cancer cells (7) 7
cells (7) 7
chemotherapy (7) 7
health aspects (7) 7
phenotype (7) 7
prognosis (7) 7
tumors (7) 7
adaptor proteins, signal transducing - metabolism (6) 6
autophagy (6) 6
biophysics (6) 6
cell line (6) 6
deubiquitinase (6) 6
drug resistance (6) 6
gene expression regulation, neoplastic (6) 6
genetics (6) 6
glioblastoma (6) 6
in-vivo (6) 6
kinases (6) 6
medical prognosis (6) 6
mutations (6) 6
pancreatic ductal adenocarcinoma (6) 6
proteasome (6) 6
proteasome endopeptidase complex - metabolism (6) 6
ubiquitin - metabolism (6) 6
ubiquitin ligase (6) 6
adolescent (5) 5
apoptosis - genetics (5) 5
biology (5) 5
breast-cancer (5) 5
child (5) 5
deubiquitinase inhibition (5) 5
deubiquitinase usp9x (5) 5
deubiquitinating enzymes (5) 5
deubiquitylating enzyme (5) 5
deubiquitylation (5) 5
development and progression (5) 5
endopeptidases - genetics (5) 5
fam (5) 5
gene expression (5) 5
gene-expression (5) 5
genes (5) 5
growth (5) 5
hela cells (5) 5
hippo pathway (5) 5
immunohistochemistry (5) 5
intellectual disability (5) 5
ligases (5) 5
lung cancer (5) 5
lung neoplasms - metabolism (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Deubiquitylase USP9X maintains centriolar satellite integrity by stabilizing pericentriolar material 1 protein
by Han, Ke-Jun and Wu, Zhiping and Pearson, Chad G and Peng, Junmin and Song, Kunhua and Liu, Chang-Wei
Journal of cell science, ISSN 0021-9533, 01/2019, Volume 132, Issue 2, p. jcs221663
Centriolar satellites are small cytoplasmic granules that play important roles in regulating the formation of centrosomes and primary cilia. Ubiquitylation of... 
Deubiquitylation | PCM1 | Centriolar satellites | Deubiquitylase | USP9X | LOCALIZATION | CILIOPATHIES | CILIUM | CENTROSOMAL PROTEIN | CELL BIOLOGY | GENE | INTERACTS | COMPONENT | MUTATIONS | CEP290 | DEUBIQUITINASE USP9X
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text A Feedback Loop Regulation Of LINC01433 And YAP Promotes Malignant Behavior In Gastric Cancer Cells
by Zhang, Cao and Qian, Haiquan and Liu, Ke and Zhao, Wei and Wang, Lei
OncoTargets and Therapy, ISSN 1178-6930, 10/2019, Volume 12, pp. 7949 - 7962
Cao Zhang,* Haiquan Qian,* Ke Liu, Wei Zhao, Lei Wang The Department of Gastrointestinal Surgery, General Hospital of Ningxia Medical University, Yinchuan... 
LATS1 | YAP | USP9X | protein stability
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text RNA sequencing identifies a novel USP9X‐USP6 promoter swap gene fusion in a primary aneurysmal bone cyst
by Blackburn, Patrick R and Davila, Jaime I and Jackson, Rory A and Fadra, Numrah and Atiq, Mazen A and Pitel, Beth A and Nair, Asha A and VanDeWalker, Todd J and Hessler, Mark G and Hovel, Sara K and Wehrs, Rebecca N and Fritchie, Karen J and Jenkins, Robert B and Halling, Kevin C and Geiersbach, Katherine B
Genes, Chromosomes and Cancer, ISSN 1045-2257, 08/2019, Volume 58, Issue 8, pp. 589 - 594
Primary aneurysmal bone cyst (ABC) is a benign multiloculated cystic lesion of bone that is defined cytogenetically by USP6 gene rearrangements. Rearrangements... 
RNA sequencing | aneurysmal bone cyst | USP9X‐USP6 | gene fusion | USP9X-USP6 | ACTIVATION | NEOPLASMS | REARRANGEMENTS | USP6 ONCOGENE | ONCOLOGY | RECURRENT | GENETICS & HEREDITY | NODULAR FASCIITIS | SPECTRUM | CELL | FAM/USP9X | Genetic research | Swaps (Finance) | RNA | Genes | Ubiquitin | Translocation | Femur | Exons | Aneurysm | Fluorescence | Reverse transcription | Bone tumors | Hybridization | Ribonucleic acid--RNA | Substrates | Gene fusion | Gene sequencing | Polymerase chain reaction | Cysts | Fluorescence in situ hybridization | Tumor suppressor genes | Bone | Tumors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics
by Chen, Xiangling and Lu, Dayun and Gao, Jing and Zhu, Hongwen and Zhou, Yanting and Gao, Daming and Zhou, Hu
Journal of Proteome Research, ISSN 1535-3893, 06/2019, Volume 18, Issue 6, pp. 2654 - 2665
The deubiquitinase USP9X is involved in multiple diseases including neurodegeneration, epilepsy, and various types of tumors by targeting different substrates.... 
SILAC | NFX1-123 | USP9X | deubiquitinase | quantitative proteomics | STABILIZATION | TRANSCRIPTION | BIOCHEMICAL RESEARCH METHODS | BINDING-PROTEINS | HPV | UBIQUITINATION | HUMAN-PAPILLOMAVIRUS 16E6 | INTERACTS | TELOMERASE ACTIVITY | EXPRESSION | DEUBIQUITINASE USP9X
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling
by Johnson, Brett V and Kumar, Raman and Oishi, Sabrina and Alexander, Suzy and Kasherman, Maria and Vega, Michelle Sanchez and Ivancevic, Atma and Gardner, Alison and Domingo, Deepti and Corbett, Mark and Parnell, Euan and Yoon, Sehyoun and Oh, Tracey and Lines, Matthew and Lefroy, Henrietta and Kini, Usha and Van Allen, Margot and Grønborg, Sabine and Mercier, Sandra and Küry, Sébastien and Bézieau, Stéphane and Pasquier, Laurent and Raynaud, Martine and Afenjar, Alexandra and Billette de Villemeur, Thierry and Keren, Boris and Désir, Julie and Van Maldergem, Lionel and Marangoni, Martina and Dikow, Nicola and Koolen, David A and VanHasselt, Peter M and Weiss, Marjan and Zwijnenburg, Petra and Sa, Joaquim and Reis, Claudia Falcao and López-Otín, Carlos and Santiago-Fernández, Olaya and Fernández-Jaén, Alberto and Rauch, Anita and Steindl, Katharina and Joset, Pascal and Goldstein, Amy and Madan-Khetarpal, Suneeta and Infante, Elena and Zackai, Elaine and Mcdougall, Carey and Narayanan, Vinodh and Ramsey, Keri and Mercimek-Andrews, Saadet and Pena, Loren and Shashi, Vandana and Schoch, Kelly and Sullivan, Jennifer A and Pinto E Vairo, Filippo and Pichurin, Pavel N and Ewing, Sarah A and Barnett, Sarah S and Klee, Eric W and Perry, M Scott and Koenig, Mary Kay and Keegan, Catherine E and Schuette, Jane L and Asher, Stephanie and Perilla-Young, Yezmin and Smith, Laurie D and Rosenfeld, Jill A and Bhoj, Elizabeth and Kaplan, Paige and Li, Dong and Oegema, Renske and van Binsbergen, Ellen and van der Zwaag, Bert and Smeland, Marie Falkenberg and Cutcutache, Ioana and Page, Matthew and Armstrong, Martin and Lin, Angela E and Steeves, Marcie A and Hollander, Nicolette den and Hoffer, Mariëtte J V and Reijnders, Margot R F and Demirdas, Serwet and Koboldt, Daniel C and Bartholomew, Dennis and Mosher, Theresa Mihalic and Hickey, Scott E and Shieh, Christine and Sanchez-Lara, Pedro A and Graham, Jr, John M and Tezcan, Kamer and Schaefer, G B and Danylchuk, Noelle R and Asamoah, Alexander and Jackson, Kelly E and Yachelevich, Naomi and Au, Margaret and Pérez-Jurado, Luis A and Kleefstra, Tjitske and Penzes, Peter and ... and Undiagnosed Diseases Network
Biological psychiatry, ISSN 0006-3223, 06/2019
The X-chromosome gene USP9X encodes a deubiquitylating enzyme that has been associated with neurodevelopmental disorders primarily in female subjects. USP9X... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Effect of Low Expression of USP9X on the Growth and Apoptosis of Glioma U251 Cells
by Hu, Jing and Xie, Conghua
Medical Journal of Wuhan University, ISSN 1671-8852, 07/2017, Volume 38, Issue 4, pp. 556 - 559
Glioma | USP9X | Apoptosis
Journal Article
Details down arrow
7. Full Text Elevated expression of USP9X correlates with poor prognosis in human non-small cell lung cancer
by Wang, You and Liu, Yu and Yang, Bo and Cao, Hong and Yang, Chun-Xu and Ouyang, Wen and Zhang, Shi-Min and Yang, Gui-Fang and Zhou, Fu-Xiang and Zhou, Yun-Feng and Xie, Cong-Hua
Journal of Thoracic Disease, ISSN 2072-1439, 2015, Volume 7, Issue 4, pp. 672 - 679
Background: The aim of this study was to investigate the expression of ubiquitin-specific peptidase 9, X-linked (USP9X) in non-small cell lung cancer (NSCLC)... 
Immunohistochemistry | Prognosis | Ubiquitin-specific peptidase 9, X-linked (USP9X) | Non-small cell lung cancer (NSCLC) | THERAPY | RESPIRATORY SYSTEM | UBIQUITIN | X-linked (USP9X) | Ubiquitin-specific peptidase 9 | immunohistochemistry | BETA-CATENIN | prognosis | non-small cell lung cancer (NSCLC) | DEUBIQUITINATING ENZYMES | FAM/USP9X | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis
by Shang, ZS and Zhao, J and Zhang, Q and Cao, C and Tian, SS and Zhang, K and Liu, L and Shi, L and Yu, N and Yang, SD
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 06/2019, Volume 294, Issue 25, pp. 9844 - 9857
Hyperactivation of the canonical Wnt-signaling pathway is a prominent feature of a number of human malignancies. Transcriptional activation of this signaling... 
MULTIPLE-MYELOMA | PYGOPUS | COMPLEX | LEGLESS | Wnt pathway | ubiquitin-specific peptidase 9 | USP9X | FAT-FACETS | BIOCHEMISTRY & MOLECULAR BIOLOGY | breast cancer | X-linked (USP9X) | BETA-CATENIN | lymphoma 9 (BCL9) | Lys-63-linked polyubiquitins | deubiquitylation (deubiquitination) | carcinogenesis | GENE | cell signaling | B-cell CLL | EXPRESSION | BINDING
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text A synthetic cell-penetrating dominant-negative ATF5 peptide exerts anti-cancer activity against a broad spectrum of treatment resistant cancers
by Karpel-Massler, Georg and Horst, Basil A and Shu, Chang and Chau, Lily and Tsujiuchi, Takashi and Bruce, Jeffrey N and Canoll, Peter and Greene, Lloyd A and Angelastro, James M and Siegelin, Markus D
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 9/2016, Volume 22, Issue 18, pp. 4698 - 4711
ABT263 | apoptosis | Usp9X | ATF5 | cell-penetrating peptide
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line
by Furuta, Haruka and Yoshihara, Hidehito and Fukushima, Toshiaki and Yoneyama, Yosuke and Ito, Akihiro and Worrall, Claire and Girnita, Ada and Girnita, Leonard and Yoshida, Minoru and Asano, Tomoichiro and Komada, Masayuki and Kataoka, Naoyuki and Chida, Kazuhiro and Hakuno, Fumihiko and Takahashi, Shin-Ichiro
Oncotarget, ISSN 1949-2553, 09/2018, Volume 9, Issue 74, pp. 33871 - 33883
Insulin-like growth factors (IGFs) have been shown to induce proliferation of many types of cells. Insulin receptor substrates (IRSs) are major targets of... 
Ubiquitin | IGF-I | IRS-2 | USP9X | Prostate cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text DUBbing Down Translation: The Functional Interaction of Deubiquitinases with the Translational Machinery
by Kapadia, BB and Gartenhaus, RB
MOLECULAR CANCER THERAPEUTICS, ISSN 1535-7163, 09/2019, Volume 18, Issue 9, pp. 1475 - 1483
Cancer cells revamp the regulatory processes that control translation to induce tumor-specific translational programs that can adapt to a hostile... 
USP15 | ACTIVATION | MITOXANTRONE | INHIBITION | ONCOLOGY | USP21 | INITIATION | USP9X | UBIQUITIN | IN-VIVO | BINDING-PROTEIN
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text LBcl-xL inhibition - a novel strategy for glioma therapy
by Karpel-Massler, Georg and Siegelin, Markus D
Aging, ISSN 1945-4589, 2016, Volume 8, Issue 9, pp. 1830 - 1831
ABT263 | Usp9X | L-asparaginase | Glioblastoma | Apoptosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Prevalence and architecture of de novo mutations in developmental disorders
by McRae, Jeremy F and Clayton, Stephen and Fitzgerald, Tomas W and Kaplanis, Joanna and Prigmore, Elena and Rajan, Diana and Sifrim, Alejandro and Aitken, Stuart and Akawi, Nadia and Alvi, Mohsan and Ambridge, Kirsty and Barrett, Daniel M and Bayzetinova, Tanya and Jones, Philip and Jones, Wendy D and King, Daniel and Krishnappa, Netravathi and Mason, Laura E and Singh, Tarjinder and Tivey, Adrian R and Ahmed, Munaza and Anjum, Uruj and Archer, Hayley and Armstrong, Ruth and Awada, Jana and Balasubramanian, Meena and Banka, Siddharth and Baralle, Diana and Barnicoat, Angela and Batstone, Paul and Baty, David and Bennett, Chris and Berg, Jonathan and Bernhard, Birgitta and Bevan, A. Paul and Bitner-Glindzicz, Maria and Blair, Edward and Blyth, Moira and Bohanna, David and Bourdon, Louise and Bourn, David and Bradley, Lisa and Brady, Angela and Brent, Simon and Brewer, Carole and Brunstrom, Kate and Bunyan, David J and Burn, John and Canham, Natalie and Castle, Bruce and Chandler, Kate and Chatzimichali, Elena and Cilliers, Deirdre and Clarke, Angus and Clasper, Susan and Clayton-Smith, Jill and Clowes, Virginia and Coates, Andrea and Cole, Trevor and Colgiu, Irina and Collins, Amanda and Collinson, Morag N and Connell, Fiona and Cooper, Nicola and Cox, Helen and Cresswell, Lara and Cross, Gareth and Crow, Yanick and D'Alessandro, Mariella and Dabir, Tabib and Davidson, Rosemarie and Davies, Sally and De Vries, Dylan and Dean, John and Deshpande, Charu and Devlin, Gemma and Dixit, Abhijit and Dobbie, Angus and Donaldson, Alan and Donnai, Dian and Donnelly, Deirdre and Donnelly, Carina and Douglas, Angela and Douzgou, Sofia and Duncan, Alexis and Eason, Jacqueline and Ellard, Sian and Ellis, Ian and Elmslie, Frances and Evans, Karenza and Everest, Sarah and Fendick, Tina and Fisher, Richard and Flinter, Frances and Foulds, Nicola and Fry, Andrew and Fryer, Alan and Gardiner, Carol and Gaunt, Lorraine and Ghali, Neeti and ... and Deciphering Developmental Disorders Study
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 433 - 438
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important... 
INTELLECTUAL DISABILITY | METAANALYSIS | VARIANTS | GENETICS | HEART-DEFECTS | MULTIDISCIPLINARY SCIENCES | GENES | SEQUENCE | FRAMEWORK | DISCOVERY | GENOME | Prevalence | Humans | Middle Aged | Parents | Male | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Developmental Disabilities - genetics | Casein Kinase II - genetics | Autoantigens - genetics | Young Adult | ras GTPase-Activating Proteins - genetics | Adult | Female | Child | CDC2 Protein Kinase - genetics | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - genetics | Sex Characteristics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Phenotype | Myeloid-Lymphoid Leukemia Protein - genetics | Adolescent | Heredity - genetics | Protein Phosphatase 2C - genetics | Cohort Studies | Child development deviations | Genetic aspects | Genetic disorders | Developmental disabilities | Distribution | Genes | Families & family life | Births | Genomes | Mutation | Causality | Estimates | Age | TRIO | MYT1L | EHMT1 | HNRNPU | SUV420H1 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SCN1A | MEF2C | CDKL5 | CSNK2A1 | DYRK1A | CASK | ALG13 | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | PhenIcons | SET | KMT2A | ANKRD11 | STXBP1 | FOXG1 | ZC4H2 | ITPR1 | De novo mutation | Seizures | ZBTB18 | CREBBP | SMAD4 | PDHA1 | IQSEC2 | AUTS2 | BCL11A | BRAF | SMARCA2 | GRIN2B | MED13L | GNAO1 | CNOT3 | TCF4 | SCN2A | CDK13 | GABRB3 | SETD5 | KDM5B | Developmental Disease | DDX3X | CHD8 | PTEN | CHD4 | TCF20 | CTCF | CHD2 | WDR45 | SLC6A1 | MECP2 | CHAMP1 | KIF1A | Average Faces | MSL3 | PPP2R5D | SMC1A | ARID1B | DNM1 | CNKSR2 | PACS1 | WAC | ZMYND11 | AHDC1 | NFIX | SATB2 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | Intellectual Disability | SLC35A2 | DYNC1H1 | NAA10 | USP9X | PTPN11 | GATAD2B | ASXL1 | KANSL1 | ASXL3 | CTNNB1 | QRICH1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Expression of USP9X in non-small cell lung cancer and its clinical significance
by Peng, Jing and Hu, Qian and Liu, Wei-Phig and Liu, Shan-Ling and Wang, He
Journal of Sichuan University (Medical Science Edition), ISSN 1672-173X, 05/2015, Volume 46, Issue 3, pp. 413 - 416
Immunohistochemistry | USP9X | Survival | Lung neoplasms
Journal Article
Details down arrow
15. Full Text USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B‐cell lymphoma
by Engel, Katharina and Rudelius, Martina and Slawska, Jolanta and Jacobs, Laura and Ahangarian Abhari, Behnaz and Altmann, Bettina and Kurutz, Julia and Rathakrishnan, Abirami and Fernández‐Sáiz, Vanesa and Brunner, Andrä and Targosz, Bianca‐Sabrina and Loewecke, Felicia and Gloeckner, Christian Johannes and Ueffing, Marius and Fulda, Simone and Pfreundschuh, Michael and Trümper, Lorenz and Klapper, Wolfram and Keller, Ulrich and Jost, Philipp J and Rosenwald, Andreas and Peschel, Christian and Bassermann, Florian
EMBO Molecular Medicine, ISSN 1757-4676, 08/2016, Volume 8, Issue 8, pp. 851 - 862
The mitotic spindle assembly checkpoint (SAC) maintains genome stability and marks an important target for antineoplastic therapies. However, it has remained... 
XIAP | USP | mitosis | B‐cell lymphoma | ubiquitin | USP9X | B-cell lymphoma | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | DEUBIQUITINASE INHIBITION | C-MYC | BETA-CATENIN | CANCER | STRUCTURAL BASIS | ALPHA-DEPENDENT APOPTOSIS | UBIQUITYLATION | IAP | EXPRESSION | Mitosis | Humans | Cells, Cultured | Ubiquitin - metabolism | B-Lymphocytes - physiology | B-Lymphocytes - drug effects | Animals | Cell Death | Lymphoma, B-Cell - pathology | X-Linked Inhibitor of Apoptosis Protein - metabolism | Ubiquitin Thiolesterase - metabolism | Antineoplastic Agents - pharmacology | Mice | Protein Processing, Post-Translational | Drug Resistance | Disease Models, Animal | Ubiquitin | Chemotherapy | Analysis | Genomics | Lymphomas | Biochemistry | Apoptosis | Cancer | IAP protein | Therapeutic applications | Chemoresistance | XIAP protein | Genomes | Myc protein | Lymphoma | Cancer therapies | Proteins | Cell fate | Lymphocytes B | Cell death | Medical prognosis | Cell cycle | Chromosomes | Tumors | Haematology | Report | Reports
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation
by Li, Haiwen and Cui, Yu and Wei, Jun and Liu, Chao and Chen, Yuhan and Cui, Chun-Ping and Li, Lei and Zhang, Xueli and Zhang, Lingqiang
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 02/2019, Volume 33, Issue 2, pp. 2928 - 2943
The bone morphogenetic protein (BMP)-Smad signaling pathway plays a crucial role in the control of bone homeostasis by regulating osteoblast activity. It is... 
E3 ubiquitin ligase | osteoblast | PDB | DOMAIN | VCP | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | P97 | CELL BIOLOGY | BIOLOGY | AAA-ATPASE | PAGETS-DISEASE | BONE | MUTATIONS | FAM/USP9X
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text Inhibition of the deubiquitinase USP9x induces pre-B cell homeobox 1 (PBX1) degradation and thereby stimulates prostate cancer cell apoptosis
by Liu, Yan and Liu, Yan and Xu, Xiaofeng and Xu, Xiaofeng and Lin, Peng and Lin, Peng and He, Yuanming and He, Yuanming and Zhang, Yawen and Cao, Biyin and Zhang, Zubin and Zhang, Zubin and Sethi, Gautam and Liu, Jinbao and Liu, Jinbao and Zhou, Xiumin and Zhou, Xiumin and Mao, Xinliang and Mao, Xinliang
Journal of Biological Chemistry, ISSN 0021-9258, 2019, Volume 294, Issue 12, pp. 4572 - 4582
Chemoresistance is a leading obstacle in effective management of advanced prostate cancer (PCa). A better understanding of the molecular mechanisms involved in... 
ubiquitylation (ubiquitination) | pre-B cell leukemia homeobox-1 | prostate cancer | deubiquitylation (deubiquitination) | USP9x | apoptosis | cancer | cancer biology | drug resistance | protein degradation | TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | CHEMORESISTANCE
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
18. Full Text Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads
by Dupont, Sirio and Inui, Masafumi and Newfeld, Stuart J
FEBS Letters, ISSN 0014-5793, 07/2012, Volume 586, Issue 14, pp. 1913 - 1920
Polyubiquitylation leading to proteasomal degradation is a well-established mechanism for regulating TGF-β signal transduction components such as receptors and... 
Smad4/Medea | BMP | Fat facets/Fam/Usp9X | Usp15 | Ectodermin/Tif1-γ/Trim33 | DEUBIQUITINATING ENZYME | UBIQUITIN LIGASE | TUMOR SUPPRESSION | FAT FACETS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | TIF1-GAMMA | CELL FATE | LIQUID FACETS | CELL BIOLOGY | BIOPHYSICS | GROWTH | Ectodermin/Tif1-gamma/Trim33 | Endopeptidases - metabolism | Humans | Gene Expression Regulation | Ubiquitin - metabolism | Smad4 Protein - metabolism | Transcription Factors - metabolism | Ubiquitin-Specific Proteases | Ubiquitination | Animals | Models, Biological | Ubiquitin Thiolesterase - metabolism | Signal Transduction - physiology | Mice | Models, Genetic | Proteasome Endopeptidase Complex - metabolism | Transforming Growth Factor beta - metabolism | Usp9X | Smad4 | Fam | Medea | Fat facets | Tif1-γ | Trim33 | Ectodermin
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights