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usp9x (89) 89
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Journal of cell science, ISSN 0021-9533, 01/2019, Volume 132, Issue 2, p. jcs221663
Centriolar satellites are small cytoplasmic granules that play important roles in regulating the formation of centrosomes and primary cilia. Ubiquitylation of... 
Deubiquitylation | PCM1 | Centriolar satellites | Deubiquitylase | USP9X | LOCALIZATION | CILIOPATHIES | CILIUM | CENTROSOMAL PROTEIN | CELL BIOLOGY | GENE | INTERACTS | COMPONENT | MUTATIONS | CEP290 | DEUBIQUITINASE USP9X
Journal Article
OncoTargets and Therapy, ISSN 1178-6930, 10/2019, Volume 12, pp. 7949 - 7962
Cao Zhang,* Haiquan Qian,* Ke Liu, Wei Zhao, Lei Wang The Department of Gastrointestinal Surgery, General Hospital of Ningxia Medical University, Yinchuan... 
LATS1 | YAP | USP9X | protein stability
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 06/2019, Volume 18, Issue 6, pp. 2654 - 2665
The deubiquitinase USP9X is involved in multiple diseases including neurodegeneration, epilepsy, and various types of tumors by targeting different substrates.... 
SILAC | NFX1-123 | USP9X | deubiquitinase | quantitative proteomics | STABILIZATION | TRANSCRIPTION | BIOCHEMICAL RESEARCH METHODS | BINDING-PROTEINS | HPV | UBIQUITINATION | HUMAN-PAPILLOMAVIRUS 16E6 | INTERACTS | TELOMERASE ACTIVITY | EXPRESSION | DEUBIQUITINASE USP9X
Journal Article
by Johnson, Brett V and Kumar, Raman and Oishi, Sabrina and Alexander, Suzy and Kasherman, Maria and Vega, Michelle Sanchez and Ivancevic, Atma and Gardner, Alison and Domingo, Deepti and Corbett, Mark and Parnell, Euan and Yoon, Sehyoun and Oh, Tracey and Lines, Matthew and Lefroy, Henrietta and Kini, Usha and Van Allen, Margot and Grønborg, Sabine and Mercier, Sandra and Küry, Sébastien and Bézieau, Stéphane and Pasquier, Laurent and Raynaud, Martine and Afenjar, Alexandra and Billette de Villemeur, Thierry and Keren, Boris and Désir, Julie and Van Maldergem, Lionel and Marangoni, Martina and Dikow, Nicola and Koolen, David A and VanHasselt, Peter M and Weiss, Marjan and Zwijnenburg, Petra and Sa, Joaquim and Reis, Claudia Falcao and López-Otín, Carlos and Santiago-Fernández, Olaya and Fernández-Jaén, Alberto and Rauch, Anita and Steindl, Katharina and Joset, Pascal and Goldstein, Amy and Madan-Khetarpal, Suneeta and Infante, Elena and Zackai, Elaine and Mcdougall, Carey and Narayanan, Vinodh and Ramsey, Keri and Mercimek-Andrews, Saadet and Pena, Loren and Shashi, Vandana and Schoch, Kelly and Sullivan, Jennifer A and Pinto E Vairo, Filippo and Pichurin, Pavel N and Ewing, Sarah A and Barnett, Sarah S and Klee, Eric W and Perry, M Scott and Koenig, Mary Kay and Keegan, Catherine E and Schuette, Jane L and Asher, Stephanie and Perilla-Young, Yezmin and Smith, Laurie D and Rosenfeld, Jill A and Bhoj, Elizabeth and Kaplan, Paige and Li, Dong and Oegema, Renske and van Binsbergen, Ellen and van der Zwaag, Bert and Smeland, Marie Falkenberg and Cutcutache, Ioana and Page, Matthew and Armstrong, Martin and Lin, Angela E and Steeves, Marcie A and Hollander, Nicolette den and Hoffer, Mariëtte J V and Reijnders, Margot R F and Demirdas, Serwet and Koboldt, Daniel C and Bartholomew, Dennis and Mosher, Theresa Mihalic and Hickey, Scott E and Shieh, Christine and Sanchez-Lara, Pedro A and Graham, Jr, John M and Tezcan, Kamer and Schaefer, G B and Danylchuk, Noelle R and Asamoah, Alexander and Jackson, Kelly E and Yachelevich, Naomi and Au, Margaret and Pérez-Jurado, Luis A and Kleefstra, Tjitske and Penzes, Peter and ... and Undiagnosed Diseases Network
Biological psychiatry, ISSN 0006-3223, 06/2019
The X-chromosome gene USP9X encodes a deubiquitylating enzyme that has been associated with neurodevelopmental disorders primarily in female subjects. USP9X... 
Journal Article
Medical Journal of Wuhan University, ISSN 1671-8852, 07/2017, Volume 38, Issue 4, pp. 556 - 559
Journal Article
Journal of Thoracic Disease, ISSN 2072-1439, 2015, Volume 7, Issue 4, pp. 672 - 679
Background: The aim of this study was to investigate the expression of ubiquitin-specific peptidase 9, X-linked (USP9X) in non-small cell lung cancer (NSCLC)... 
Immunohistochemistry | Prognosis | Ubiquitin-specific peptidase 9, X-linked (USP9X) | Non-small cell lung cancer (NSCLC) | THERAPY | RESPIRATORY SYSTEM | UBIQUITIN | X-linked (USP9X) | Ubiquitin-specific peptidase 9 | immunohistochemistry | BETA-CATENIN | prognosis | non-small cell lung cancer (NSCLC) | DEUBIQUITINATING ENZYMES | FAM/USP9X | Original
Journal Article
by Shang, ZS and Zhao, J and Zhang, Q and Cao, C and Tian, SS and Zhang, K and Liu, L and Shi, L and Yu, N and Yang, SD
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 06/2019, Volume 294, Issue 25, pp. 9844 - 9857
Hyperactivation of the canonical Wnt-signaling pathway is a prominent feature of a number of human malignancies. Transcriptional activation of this signaling... 
MULTIPLE-MYELOMA | PYGOPUS | COMPLEX | LEGLESS | Wnt pathway | ubiquitin-specific peptidase 9 | USP9X | FAT-FACETS | BIOCHEMISTRY & MOLECULAR BIOLOGY | breast cancer | X-linked (USP9X) | BETA-CATENIN | lymphoma 9 (BCL9) | Lys-63-linked polyubiquitins | deubiquitylation (deubiquitination) | carcinogenesis | GENE | cell signaling | B-cell CLL | EXPRESSION | BINDING
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 9/2016, Volume 22, Issue 18, pp. 4698 - 4711
Journal Article
Oncotarget, ISSN 1949-2553, 09/2018, Volume 9, Issue 74, pp. 33871 - 33883
Insulin-like growth factors (IGFs) have been shown to induce proliferation of many types of cells. Insulin receptor substrates (IRSs) are major targets of... 
Ubiquitin | IGF-I | IRS-2 | USP9X | Prostate cancer
Journal Article
MOLECULAR CANCER THERAPEUTICS, ISSN 1535-7163, 09/2019, Volume 18, Issue 9, pp. 1475 - 1483
Cancer cells revamp the regulatory processes that control translation to induce tumor-specific translational programs that can adapt to a hostile... 
USP15 | ACTIVATION | MITOXANTRONE | INHIBITION | ONCOLOGY | USP21 | INITIATION | USP9X | UBIQUITIN | IN-VIVO | BINDING-PROTEIN
Journal Article
Aging, ISSN 1945-4589, 2016, Volume 8, Issue 9, pp. 1830 - 1831
Journal Article
by McRae, Jeremy F and Clayton, Stephen and Fitzgerald, Tomas W and Kaplanis, Joanna and Prigmore, Elena and Rajan, Diana and Sifrim, Alejandro and Aitken, Stuart and Akawi, Nadia and Alvi, Mohsan and Ambridge, Kirsty and Barrett, Daniel M and Bayzetinova, Tanya and Jones, Philip and Jones, Wendy D and King, Daniel and Krishnappa, Netravathi and Mason, Laura E and Singh, Tarjinder and Tivey, Adrian R and Ahmed, Munaza and Anjum, Uruj and Archer, Hayley and Armstrong, Ruth and Awada, Jana and Balasubramanian, Meena and Banka, Siddharth and Baralle, Diana and Barnicoat, Angela and Batstone, Paul and Baty, David and Bennett, Chris and Berg, Jonathan and Bernhard, Birgitta and Bevan, A. Paul and Bitner-Glindzicz, Maria and Blair, Edward and Blyth, Moira and Bohanna, David and Bourdon, Louise and Bourn, David and Bradley, Lisa and Brady, Angela and Brent, Simon and Brewer, Carole and Brunstrom, Kate and Bunyan, David J and Burn, John and Canham, Natalie and Castle, Bruce and Chandler, Kate and Chatzimichali, Elena and Cilliers, Deirdre and Clarke, Angus and Clasper, Susan and Clayton-Smith, Jill and Clowes, Virginia and Coates, Andrea and Cole, Trevor and Colgiu, Irina and Collins, Amanda and Collinson, Morag N and Connell, Fiona and Cooper, Nicola and Cox, Helen and Cresswell, Lara and Cross, Gareth and Crow, Yanick and D'Alessandro, Mariella and Dabir, Tabib and Davidson, Rosemarie and Davies, Sally and De Vries, Dylan and Dean, John and Deshpande, Charu and Devlin, Gemma and Dixit, Abhijit and Dobbie, Angus and Donaldson, Alan and Donnai, Dian and Donnelly, Deirdre and Donnelly, Carina and Douglas, Angela and Douzgou, Sofia and Duncan, Alexis and Eason, Jacqueline and Ellard, Sian and Ellis, Ian and Elmslie, Frances and Evans, Karenza and Everest, Sarah and Fendick, Tina and Fisher, Richard and Flinter, Frances and Foulds, Nicola and Fry, Andrew and Fryer, Alan and Gardiner, Carol and Gaunt, Lorraine and Ghali, Neeti and ... and Deciphering Developmental Disorders Study
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 433 - 438
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important... 
INTELLECTUAL DISABILITY | METAANALYSIS | VARIANTS | GENETICS | HEART-DEFECTS | MULTIDISCIPLINARY SCIENCES | GENES | SEQUENCE | FRAMEWORK | DISCOVERY | GENOME | Prevalence | Humans | Middle Aged | Parents | Male | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Developmental Disabilities - genetics | Casein Kinase II - genetics | Autoantigens - genetics | Young Adult | ras GTPase-Activating Proteins - genetics | Adult | Female | Child | CDC2 Protein Kinase - genetics | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - genetics | Sex Characteristics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Phenotype | Myeloid-Lymphoid Leukemia Protein - genetics | Adolescent | Heredity - genetics | Protein Phosphatase 2C - genetics | Cohort Studies | Child development deviations | Genetic aspects | Genetic disorders | Developmental disabilities | Distribution | Genes | Families & family life | Births | Genomes | Mutation | Causality | Estimates | Age | TRIO | MYT1L | EHMT1 | HNRNPU | SUV420H1 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SCN1A | MEF2C | CDKL5 | CSNK2A1 | DYRK1A | CASK | ALG13 | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | PhenIcons | SET | KMT2A | ANKRD11 | STXBP1 | FOXG1 | ZC4H2 | ITPR1 | De novo mutation | Seizures | ZBTB18 | CREBBP | SMAD4 | PDHA1 | IQSEC2 | AUTS2 | BCL11A | BRAF | SMARCA2 | GRIN2B | MED13L | GNAO1 | CNOT3 | TCF4 | SCN2A | CDK13 | GABRB3 | SETD5 | KDM5B | Developmental Disease | DDX3X | CHD8 | PTEN | CHD4 | TCF20 | CTCF | CHD2 | WDR45 | SLC6A1 | MECP2 | CHAMP1 | KIF1A | Average Faces | MSL3 | PPP2R5D | SMC1A | ARID1B | DNM1 | CNKSR2 | PACS1 | WAC | ZMYND11 | AHDC1 | NFIX | SATB2 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | Intellectual Disability | SLC35A2 | DYNC1H1 | NAA10 | USP9X | PTPN11 | GATAD2B | ASXL1 | KANSL1 | ASXL3 | CTNNB1 | QRICH1
Journal Article
Journal of Sichuan University (Medical Science Edition), ISSN 1672-173X, 05/2015, Volume 46, Issue 3, pp. 413 - 416
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 08/2016, Volume 8, Issue 8, pp. 851 - 862
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 02/2019, Volume 33, Issue 2, pp. 2928 - 2943
The bone morphogenetic protein (BMP)-Smad signaling pathway plays a crucial role in the control of bone homeostasis by regulating osteoblast activity. It is... 
E3 ubiquitin ligase | osteoblast | PDB | DOMAIN | VCP | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | P97 | CELL BIOLOGY | BIOLOGY | AAA-ATPASE | PAGETS-DISEASE | BONE | MUTATIONS | FAM/USP9X
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2019, Volume 294, Issue 12, pp. 4572 - 4582
Chemoresistance is a leading obstacle in effective management of advanced prostate cancer (PCa). A better understanding of the molecular mechanisms involved in... 
ubiquitylation (ubiquitination) | pre-B cell leukemia homeobox-1 | prostate cancer | deubiquitylation (deubiquitination) | USP9x | apoptosis | cancer | cancer biology | drug resistance | protein degradation | TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | CHEMORESISTANCE
Journal Article