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ubc9 (113) 113
science & technology (111) 111
life sciences & biomedicine (106) 106
humans (85) 85
sumoylation (64) 64
animals (59) 59
ubiquitin-conjugating enzymes - metabolism (56) 56
biochemistry & molecular biology (54) 54
sumo (51) 51
cell biology (49) 49
ubiquitin-conjugating enzymes - genetics (42) 42
small ubiquitin-related modifier proteins - metabolism (41) 41
enzymes (38) 38
sumo-1 protein - metabolism (35) 35
ubiquitin (31) 31
proteins (28) 28
protein binding (22) 22
amino acid sequence (21) 21
mice (21) 21
male (19) 19
molecular sequence data (18) 18
signal transduction (18) 18
female (17) 17
gene expression (17) 17
hela cells (17) 17
small ubiquitin-related modifier proteins - genetics (16) 16
biological and medical sciences (15) 15
genetic aspects (15) 15
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nuclear proteins - metabolism (12) 12
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ubiquitins - metabolism (12) 12
biology (11) 11
enzymes and coenzymes (11) 11
small ubiquitin-like modifier (11) 11
sumo-1 protein - genetics (11) 11
two-hybrid system techniques (11) 11
cells, cultured (10) 10
mutation (10) 10
sumo protein (10) 10
transcription factors - metabolism (10) 10
cell line, tumor (9) 9
cellular biology (9) 9
dna-binding proteins - metabolism (9) 9
fundamental and applied biological sciences. psychology (9) 9
ligases - metabolism (9) 9
lysine (9) 9
medical sciences (9) 9
middle aged (9) 9
models, molecular (9) 9
molecular biology (9) 9
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phosphorylation (9) 9
physiological aspects (9) 9
protein structure, tertiary (9) 9
ubc9 protein (9) 9
ubiquitin-conjugating enzymes (9) 9
amino acid motifs (8) 8
analysis (8) 8
apoptosis (8) 8
binding sites (8) 8
breast cancer (8) 8
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small ubiquitin-related modifier proteins - chemistry (8) 8
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ubiquitin-conjugating enzymes - physiology (8) 8
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genetic processes (7) 7
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hek293 cells (7) 7
post-translation (7) 7
recombinant fusion proteins - metabolism (7) 7
repressor proteins - metabolism (7) 7
research article (7) 7
sumo-1 protein (7) 7
transcription, genetic (7) 7
transcriptional activation (7) 7
ubiquitin-protein ligases - metabolism (7) 7
ubiquitination (7) 7
aged (6) 6
blotting, western (6) 6
breast neoplasms - genetics (6) 6
cell cycle (6) 6
cell nucleus - metabolism (6) 6
cell proliferation (6) 6
genetics & heredity (6) 6
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1. Full Text Both conditional ablation and overexpression of E2 SUMO-conjugating enzyme (UBC9) in mouse pancreatic beta cells result in impaired beta cell function
by He, Xiaoyu and Lai, Qiaohong and Chen, Cai and Li, Na and Sun, Fei and Huang, Wenting and Zhang, Shu and Yu, Qilin and Yang, Ping and Xiong, Fei and Chen, Zhishui and Gong, Quan and Ren, Boxu and Weng, Jianping and Eizirik, Décio L and Zhou, Zhiguang and Wang, Cong-Yi
Diabetologia, ISSN 0012-186X, 4/2018, Volume 61, Issue 4, pp. 881 - 895
Oxidative stress | Medicine & Public Health | Human Physiology | NRF2 | UBC9 | Metabolic Diseases | Pancreatic beta cell | Internal Medicine | Insulin content | Diabetes | SUMOylation | Insulin secretion | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Glucose Tolerance Test | Reactive Oxygen Species - metabolism | Blood Glucose - analysis | Oxidative Stress | Antioxidants - metabolism | Humans | Male | Ubiquitin-Conjugating Enzymes - genetics | Mice, Knockout | Animals | Time Factors | Ubiquitin-Conjugating Enzymes - metabolism | Islets of Langerhans - cytology | HEK293 Cells | Islets of Langerhans - physiopathology | Sumoylation | NF-E2-Related Factor 2 - genetics | Insulin-Secreting Cells - cytology | Mice | Lysine - chemistry | Apoptosis | Insulin-Secreting Cells - enzymology | Enzymes | Pancreatic beta cells | Genetic engineering | Sumo | Blood sugar | Ubiquitin | Secretion | Gene regulation | Diabetes mellitus | Transgenic mice | Detoxification | Glucose | Tamoxifen | Insulin | Ablation | Beta cells | SUMO protein | Antioxidants | Clonal deletion | Evolutionary conservation | Lysine | Post-translation | Regulation | Pancreas | Index Medicus
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2. Full Text Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation
by Wiechmann, Svenja and Gärtner, Anne and Kniss, Andreas and Stengl, Andreas and Behrends, Christian and Rogov, Vladimir V and Rodriguez, Manuel S and Dötsch, Volker and Müller, Stefan and Ernst, Andreas
The Journal of biological chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 37, pp. 15340 - 15351
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Humans | Promyelocytic Leukemia Protein - chemistry | Arsenic - toxicity | Recombinant Fusion Proteins - metabolism | Ubiquitin-Conjugating Enzymes - chemistry | Sumoylation - drug effects | Small Ubiquitin-Related Modifier Proteins - genetics | RNA Interference | Gene Deletion | HEK293 Cells | Promyelocytic Leukemia Protein - metabolism | Protein Interaction Domains and Motifs | Binding Sites | Peptide Fragments - genetics | Promyelocytic Leukemia Protein - genetics | Binding, Competitive | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | Gene Library | Small Ubiquitin-Related Modifier Proteins - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Ubiquitin-Conjugating Enzymes - genetics | Hot Temperature | Recombinant Fusion Proteins - chemistry | Point Mutation | Peptide Fragments - chemistry | Small Ubiquitin-Related Modifier Proteins - chemistry | Ubiquitin-Conjugating Enzymes - metabolism | Promyelocytic Leukemia Protein - antagonists & inhibitors | Ligands | HeLa Cells | Ubiquitin-Conjugating Enzymes - antagonists & inhibitors | Amino Acid Substitution | Index Medicus | protein engineering | sumoylation | enzyme inhibitor | UBC9 | phage display | nuclear magnetic resonance (NMR) | heat shock | small ubiquitin-like modifier (SUMO) | PML | Cell Biology
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3. Full Text Common variants in the UBC9 gene encoding the SUMO‐conjugating enzyme are associated with breast tumor grade
by Dünnebier, Thomas and Bermejo, Justo Lorenzo and Haas, Susanne and Fischer, Hans‐Peter and Pierl, Christiane B and Justenhoven, Christina and Brauch, Hiltrud and Baisch, Christian and Gilbert, Michael and Harth, Volker and Spickenheuer, Anne and Rabstein, Sylvia and Pesch, Beate and Brüning, Thomas and Ko, Yon‐Dschun and Hamann, Ute
International journal of cancer, ISSN 0020-7136, 08/2009, Volume 125, Issue 3, pp. 596 - 602
multiple imputation | UBC9 polymorphisms | SUMOylation | breast cancer progression | tumor grade | Multiple imputation | Tumor grade | Breast cancer progression | Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Biological and medical sciences | Medical sciences | Tumors | Multivariate Analysis | Receptors, Estrogen - metabolism | Gene Frequency | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Genotype | Ubiquitin-Conjugating Enzymes - genetics | Lymphatic Metastasis | Breast Neoplasms - metabolism | Linkage Disequilibrium | Genetic Variation | Breast Neoplasms - enzymology | Breast Neoplasms - genetics | Analysis of Variance | Breast Neoplasms - pathology | Adult | Female | Aged | Polymorphism, Single Nucleotide | SUMO-1 Protein - metabolism | Odds Ratio | Index Medicus
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4. Full Text Meiosis and small ubiquitin‐related modifier (SUMO)‐conjugating enzyme, Ubc9
by Sakaguchi, Kengo and Koshiyama, Akiyo and Iwabata, Kazuki
The FEBS journal, ISSN 1742-464X, 07/2007, Volume 274, Issue 14, pp. 3519 - 3531
Rad51 | meiosis | PCNA | SUMO | sumoylation | DNA polymerase | Lim15/Dmc1 | topoisomerase II | Ubc9 | Sumoylation | Meiosis | Topoisomerase II | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | DNA-Binding Proteins - metabolism | Animals | Small Ubiquitin-Related Modifier Proteins - metabolism | Ubiquitin-Conjugating Enzymes - metabolism | Humans | Cell Cycle Proteins - metabolism | Protein Binding | DNA polymerases | Enzymes | Index Medicus
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5. Full Text Orthoreovirus outer-fiber proteins are substrates for SUMO-conjugating enzyme Ubc9
by Yu, Fei and Wang, Hao and Wang, Longlong and Lu, Liqun
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 48, pp. 79814 - 79827
SUMOylation | Ubc9 | Reovirus | Outer-fiber protein | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Reoviridae Infections - pathology | Amino Acid Sequence | Orthoreovirus - chemistry | Hemorrhage - metabolism | Reoviridae Infections - veterinary | Phylogeny | Orthoreovirus - metabolism | Viral Proteins - metabolism | Carps - virology | Sequence Alignment | Animals | Fish Diseases - virology | Ubiquitin-Conjugating Enzymes - metabolism | Protein Binding | Sumoylation | Protein Processing, Post-Translational | Reoviridae Infections - metabolism | Hemorrhage - virology | Fish Diseases - metabolism | Index Medicus
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6. Full Text Mason–Pfizer monkey virus Gag proteins interact with the human sumo conjugating enzyme, hUbc9
by Weldon, Robert A and Sarkar, Pushpita and Brown, Shanna M and Weldon, Sally K
Virology (New York, N.Y.), ISSN 0042-6822, 2003, Volume 314, Issue 1, pp. 62 - 73
Virus assembly | Yeast two-hybrid screen | COS-1 cells | Retroviridae | Ubc9 | Gag | Capsid | Mason–Pfizer monkey virus | Mason-Pfizer monkey virus | Life Sciences & Biomedicine | Science & Technology | Virology | Gene Products, gag - genetics | Humans | Ligases - genetics | Ligases - metabolism | Cytoplasm - metabolism | Gene Products, gag - chemistry | Gene Products, gag - metabolism | Protein Precursors - metabolism | Two-Hybrid System Techniques | Animals | Mason-Pfizer monkey virus - metabolism | Virus Replication | HeLa Cells | Ubiquitin-Conjugating Enzymes | COS Cells | Index Medicus
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7. Full Text HPV E6 proteins target Ubc9, the SUMO conjugating enzyme
by Heaton, Phillip R and Deyrieux, Adeline F and Bian, Xue-Lin and Wilson, Van G
Virus research, ISSN 0168-1702, 2011, Volume 158, Issue 1, pp. 199 - 208
Human papillomavirus | SUMO | Ubc9 | HaCaT | Proteomics | E6 | Life Sciences & Biomedicine | Science & Technology | Virology | Papillomaviridae - pathogenicity | Cell Line | Keratinocytes - virology | Humans | Protein Binding | Transcription, Genetic | Virulence Factors - metabolism | Ubiquitin-Conjugating Enzymes - antagonists & inhibitors | Repressor Proteins - metabolism | DNA-Binding Proteins | Oncogene Proteins, Viral - metabolism | Protein Interaction Mapping | Enzymes | Sumo | Papillomavirus infections | Protein binding | Index Medicus | proteomics | human papillomavirus
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8. Full Text Biochemical characterization of SUMO-conjugating enzymes by in vitro sumoylation assays
by Eisenhardt, Nathalie and Ilic, Dragana and Nagamalleswari, Easa and Pichler, Andrea
Methods in enzymology, ISSN 0076-6879, 01/2019, Volume 618, pp. 167 - 185
ZNF451 | RanBP2 | SUMO E2-conjugating enzyme | SUMO | Enzyme | SUMO E3 ligases | Sumoylated Ubc9 (E2) | Ubc9 | Cofactor | PIAS1 | Index Medicus
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9. Full Text Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9
by Deng, Hua and Lin, Yingbo and Badin, Margherita and Vasilcanu, Daiana and Strömberg, Thomas and Jernberg-Wiklund, Helena and Sehat, Bita and Larsson, Olle
Biochemical and biophysical research communications, ISSN 0006-291X, 2011, Volume 404, Issue 2, pp. 667 - 671
SUMOylation | Ubc9 | Nuclear | Cell nucleus | IGF-1 receptor | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Neoplasms - metabolism | Receptor, IGF Type 1 - metabolism | Cell Nucleus - metabolism | Neoplasms - genetics | Ubiquitin-Conjugating Enzymes - metabolism | Humans | Gene Expression Regulation, Neoplastic | Cell Line, Tumor | Sumoylation | Ubiquitin-Conjugating Enzymes - genetics | Cell Membrane - metabolism | Receptor, IGF Type 1 - genetics | Ligases | Tumors | Tyrosine | Enzymes | Phosphorylation | Transcription | Epithelial cells | Insulin-like growth factor I | Breast cancer | Cell membranes | Tumor cell lines | Gene expression | Nuclear transport | SUMO protein | Signal transduction | Enhancers | Lysine | Transcription activation | Index Medicus | TRANSLOCATION | MAMMARY GLANDS | NEOPLASMS | PHOSPHORYLATION | LYSINE | TRANSCRIPTION | TUMOR CELLS | 60 APPLIED LIFE SCIENCES | CELL NUCLEI | INSULIN | GROWTH FACTORS | TYROSINE | CELL MEMBRANES | LIGASES | RECEPTORS | Medicin och hälsovetenskap
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10. Full Text The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury
by Tong, Li and Tong, Li and Wu, Zhixin and Wu, Zhixin and Ran, Mingzi and Ran, Mingzi and Chen, Yu and Chen, Yu and Yang, Lujia and Yang, Lujia and Zhang, Haopeng and Zhang, Haopeng and Zhang, Lina and Zhang, Lina and Dong, Hailong and Dong, Hailong and Xiong, Lize and Xiong, Lize
Molecular neurobiology, ISSN 0893-7648, 6/2015, Volume 51, Issue 3, pp. 1221 - 1231
Neurology | Neuroprotection | Neurosciences | Biomedicine | Ischemia | Neurobiology | Ubc9 | Preconditioning | Isoflurane | Cell Biology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Anesthetics, Inhalation - pharmacology | Anesthetics, Inhalation - administration & dosage | Isoflurane - pharmacology | Humans | Isoflurane - administration & dosage | Reperfusion Injury - drug therapy | Male | Brain Ischemia - prevention & control | Sumoylation - physiology | Rats, Sprague-Dawley | Neuroprotection - drug effects | Ischemic Preconditioning - methods | Animals | Neuroprotective Agents - pharmacology | Ubiquitin-Conjugating Enzymes - metabolism | Brain Ischemia - drug therapy | Mice | SUMO-1 Protein - metabolism | Disease Models, Animal | Ubiquitin | Enzymes | RNA | Neurons | Halides | Glucose | Dextrose | Rodents | Index Medicus
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