X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
ubiquilin-2 (9) 9
als (7) 7
amyotrophic lateral sclerosis (7) 7
ubiquitin (7) 7
neurosciences (6) 6
humans (5) 5
mice (5) 5
amyotrophic-lateral-sclerosis (4) 4
index medicus (4) 4
molecular biology (4) 4
tar dna-binding protein 43 (4) 4
analysis (3) 3
animal models (3) 3
animals (3) 3
article (3) 3
autophagy (3) 3
dementia (3) 3
frontotemporal lobar degeneration (3) 3
genetic aspects (3) 3
protein binding (3) 3
transgenic mice (3) 3
aging (2) 2
amyotrophic lateral sclerosis - genetics (2) 2
amyotrophic lateral sclerosis - metabolism (2) 2
atrophy (2) 2
binding proteins (2) 2
binding sites (2) 2
cell biology (2) 2
cell cycle proteins - genetics (2) 2
cell cycle proteins - metabolism (2) 2
cellular and molecular neuroscience (2) 2
clinical neurology (2) 2
developmental biology (2) 2
disease models, animal (2) 2
dna-binding proteins - metabolism (2) 2
endoplasmic-reticulum (2) 2
female (2) 2
frontotemporal dementia (2) 2
inclusion bodies - metabolism (2) 2
linked mutations (2) 2
liquid-liquid phase separation (2) 2
medical colleges (2) 2
mental disorders (2) 2
microglia (2) 2
motor-neurons (2) 2
mouse model (2) 2
mutation (2) 2
mutation, missense (2) 2
mutations (2) 2
neuroinflammation (2) 2
neurons - metabolism (2) 2
nuclear magnetic resonance spectroscopy (2) 2
oligomers (2) 2
pathology (2) 2
proteasome endopeptidase complex - metabolism (2) 2
protein quality control (2) 2
proteins (2) 2
proteolysis (2) 2
stress, physiological (2) 2
ubiquitination (2) 2
ubiquitins - genetics (2) 2
ubiquitins - metabolism (2) 2
activated protein-kinase (1) 1
adaptor proteins, vesicular transport - genetics (1) 1
adaptor proteins, vesicular transport - metabolism (1) 1
age factors (1) 1
aged (1) 1
aged, 80 and over (1) 1
aggregation (1) 1
alpha-synuclein (1) 1
alzheimer disease - genetics (1) 1
alzheimer disease - pathology (1) 1
alzheimer's disease (1) 1
alzheimers-disease (1) 1
amyloid beta-protein (1) 1
amyotrophic lateral sclerosis - complications (1) 1
amyotrophic lateral sclerosis - pathology (1) 1
animals, newborn (1) 1
axons (1) 1
binding protein (1) 1
biochemistry & molecular biology (1) 1
biological sciences (1) 1
biomedicine (1) 1
brain - metabolism (1) 1
brain - pathology (1) 1
c9orf72 (1) 1
cell cycle proteins - chemistry (1) 1
cell cycle proteins - physiology (1) 1
cell death (1) 1
cell nucleus - metabolism (1) 1
cells (1) 1
cerebellum (1) 1
chromatography (1) 1
chromosomes (1) 1
clearance (1) 1
cognitive ability (1) 1
cortex (1) 1
cytoplasm - metabolism (1) 1
cytoplasmic granules - metabolism (1) 1
cytosol - metabolism (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


ACTA NEUROPATHOLOGICA COMMUNICATIONS, ISSN 2051-5960, 07/2019, Volume 7, Issue 1, p. 103
Journal Article
Structure, ISSN 0969-2126, 06/2019, Volume 27, Issue 6, pp. 937 - 951.e5
Proteasomal shuttle factor UBQLN2 is recruited to stress granules and undergoes liquid-liquid phase separation (LLPS) into protein-containing droplets.... 
proline-rich | self-assembly | liquid-liquid phase separation | oligomerization | viscoelasticity | ALS | protein quality control | aggregation | ubiquitin | ubiquilin-2 | Ubiquitin | Oligomers | Medical colleges | Developmental biology | Proline | Nuclear magnetic resonance spectroscopy | Genetic aspects | Molecular biology | Chromatography
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2018, Volume 69, Issue 6, pp. 965 - 978.e6
Under stress, certain eukaryotic proteins and RNA assemble to form membraneless organelles known as stress granules. The most well-studied stress granule... 
LLPS | Ubiquilin-2 | multivalent interactions | liquid-liquid phase separation | stress granules | protein quality control | ligand-induced phase transition | NMR spectroscopy | amyotrophic lateral sclerosis | ubiquitin | INTRINSICALLY DISORDERED PROTEINS | DOMAIN | LINKED MUTATIONS | N-15 RELAXATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALS | ENDOPLASMIC-RETICULUM | SECONDARY STRUCTURE | FAMILY PROTEINS | AUTOPHAGY | STRESS GRANULES | CELL BIOLOGY | Ubiquitins - genetics | Humans | Cell Cycle Proteins - metabolism | Stress, Physiological | Models, Molecular | Ubiquitins - chemistry | Structure-Activity Relationship | Intrinsically Disordered Proteins - genetics | Protein Aggregation, Pathological | Protein Folding | Cell Cycle Proteins - chemistry | Intrinsically Disordered Proteins - chemistry | Cytoplasmic Granules - metabolism | Cell Cycle Proteins - genetics | Protein Binding | Protein Domains | Female | Protein Conformation | HeLa Cells | Proteasome Endopeptidase Complex - metabolism | Binding Sites | Ubiquitins - metabolism | Intrinsically Disordered Proteins - metabolism | Ubiquitin | Oligomers | Medical colleges | RNA | Developmental biology | Physiological aspects | Nuclear magnetic resonance spectroscopy | Liquid crystal displays | Molecular biology | Binding proteins | Protein binding | liquid- liquid phase separation (LLPS) | amyotrophic lateral sclerosis (ALS)
Journal Article
MOLECULAR NEUROBIOLOGY, ISSN 0893-7648, 07/2019, Volume 56, Issue 7, pp. 4680 - 4696
Mutations in the gene encoding ubiquilin-2 (UBQLN2) are linked to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). UBQLN2 plays a central... 
Ubiquitin | MOTOR-NEURONS | CLEARANCE | Animal models | Amyotrophic lateral sclerosis (ALS) | ALS | Neuroinflammation | AMYOTROPHIC-LATERAL-SCLEROSIS | FRONTOTEMPORAL LOBAR DEGENERATION | BINDING PROTEIN | NEUROSCIENCES | Ubiquilin-2 (UBQLN2) | MICROGLIA | Mice | TAR DNA-binding protein 43 (TDP-43) | PROTEASOME SYSTEM | NF-KAPPA-B | ONSET
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 47, pp. E7580 - E7589
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 7/2019, Volume 56, Issue 7, pp. 4680 - 4696
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 2/2013, Volume 125, Issue 2, pp. 289 - 302
An expanded GGGGCC hexanucleotide repeat in C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal lobar degeneration... 
Ubiquitin | Pathology | Ubiquilin-2 | Neurosciences | Medicine & Public Health | Frontotemporal lobar degeneration | Tau | C9ORF72 | P62 | NEUROPATHOLOGIC HETEROGENEITY | VALOSIN-CONTAINING-PROTEIN | DEMENTIA | INCLUSIONS | ALZHEIMERS-DISEASE | ALS | AMYOTROPHIC-LATERAL-SCLEROSIS | PATHOLOGY | PROGRANULIN | NEUROSCIENCES | CLINICAL NEUROLOGY | MUTATIONS | TDP-43 IMMUNOREACTIVITY | Immunohistochemistry | Frontotemporal Lobar Degeneration - pathology | Age Factors | DNA Repeat Expansion - genetics | Humans | Middle Aged | Male | Alzheimer Disease - pathology | Atrophy | tau Proteins - genetics | tau Proteins - physiology | Aged, 80 and over | Female | Neurofibrillary Tangles - pathology | Data Interpretation, Statistical | Intercellular Signaling Peptides and Proteins - genetics | Mutation - genetics | Image Processing, Computer-Assisted | Fluorescent Antibody Technique | Sex Factors | Heterozygote | Aged | Frontotemporal Lobar Degeneration - genetics | Alzheimer Disease - genetics | Microscopy, Fluorescence | Proteolysis | Analysis | Amyloid beta-protein | Amyotrophic lateral sclerosis | Binding proteins | Alzheimer's disease | Protein binding | Cerebellum | Image processing | Neurodegenerative diseases | Neuronal-glial interactions | Axons | Neurofibrillary tangles | Tau protein | Inclusion bodies | Mutation | Frontotemporal dementia | Cortex (temporal) | Hippocampus | tau | p62 | frontotemporal lobar degeneration | ubiquitin | ubiquilin-2
Journal Article
Journal Article
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.