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Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2011, Volume 31, Issue 44, pp. 15703 - 15715
Considerable evidence suggests that mitochondrial dysfunction and oxidative stress contribute to the progression of Alzheimer's disease (AD). We examined the... 
OXIDATIVE STRESS | MANGANESE SUPEROXIDE-DISMUTASE | AMYLOID-BETA-PEPTIDE | PROGRAMMED NEURONAL DEATH | A-BETA | NITRIC-OXIDE | FREE-RADICAL GENERATION | PRECURSOR PROTEIN | MILD COGNITIVE IMPAIRMENT | CYTOCHROME-C RELEASE | NEUROSCIENCES | Humans | Glial Fibrillary Acidic Protein - metabolism | Rhodamines - metabolism | Tyrosine - analogs & derivatives | Alzheimer Disease - pathology | Neurons - ultrastructure | Cell Death - genetics | Time Factors | Amyloid beta-Peptides - metabolism | Lipid Peroxidation - drug effects | Disease Models, Animal | Animals, Newborn | Enzyme Inhibitors - pharmacology | Organophosphorus Compounds - therapeutic use | Mice, Transgenic | Mitochondria - pathology | Tyrosine - metabolism | Memory Disorders - etiology | Analysis of Variance | Mice | Lipid Peroxidation - genetics | Oxidative Stress - drug effects | Enzyme-Linked Immunosorbent Assay - methods | Alzheimer Disease - complications | Age Factors | Memory Disorders - genetics | Glutathione - metabolism | Peptide Fragments - toxicity | Amyloid beta-Peptides - pharmacology | Retention (Psychology) - drug effects | Peptide Fragments - pharmacology | Cerebral Cortex - cytology | Caspases - metabolism | Space Perception - drug effects | Ubiquinone - therapeutic use | Cell Death - drug effects | Neurons - drug effects | Gliosis - prevention & control | Gliosis - etiology | Peptide Fragments - metabolism | Amyloid beta-Peptides - toxicity | Mice, Inbred C57BL | Ubiquinone - analogs & derivatives | Cells, Cultured | Oxidative Stress - genetics | Mitochondria - drug effects | Maze Learning - drug effects | Antioxidants - therapeutic use | Memory Disorders - prevention & control | Animals | Alzheimer Disease - genetics
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 769 - 780
Background Inflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). Mitochondrial oxidative stress... 
Allergy and Immunology | airway hyperresponsiveness | antioxidant | proliferation | MitoQ | inflammation | mitochondria | airway smooth muscle | Ozone | oxidative stress | chronic obstructive pulmonary disease | ASTHMA FEATURES | MECHANISMS | IMMUNOLOGY | FRAGMENTATION | HYPERRESPONSIVENESS | BETA | RESPONSES | ALLERGY | ENERGY-METABOLISM | EXPRESSION | COPD | Respiratory System - pathology | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - pathology | Bronchial Hyperreactivity - genetics | Ubiquinone - pharmacology | Muscle, Smooth - drug effects | Smoking - physiopathology | Organophosphorus Compounds - pharmacology | Myocytes, Smooth Muscle - drug effects | Pneumonia - genetics | Pulmonary Disease, Chronic Obstructive - genetics | Bronchial Hyperreactivity - chemically induced | Signal Transduction | Mitochondria - pathology | Smoking - metabolism | Bronchial Hyperreactivity - pathology | Reactive Oxygen Species - antagonists & inhibitors | Electron Transport Chain Complex Proteins - metabolism | Pulmonary Disease, Chronic Obstructive - chemically induced | Respiratory System - drug effects | Airway Remodeling - genetics | Mice | Oxidative Stress - drug effects | Bronchial Hyperreactivity - drug therapy | Myocytes, Smooth Muscle - pathology | Pneumonia - pathology | Membrane Potential, Mitochondrial - drug effects | Pneumonia - chemically induced | Adult | Female | Pulmonary Disease, Chronic Obstructive - metabolism | Myocytes, Smooth Muscle - metabolism | Ubiquinone - analogs & derivatives | Gene Expression Regulation | Hydrogen Peroxide - pharmacology | Electron Transport Chain Complex Proteins - genetics | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Muscle, Smooth - metabolism | Animals | Pneumonia - drug therapy | Respiratory System - metabolism | Aged | Muscle, Smooth - pathology | Oxidative stress | Care and treatment | Lung diseases, Obstructive | Inflammation | Pharmaceutical industry | Biomedical research | Disease | Laboratories | Mortality | Colleges & universities | Smooth muscle | Mitochondrial DNA | Metabolism | Defects | Antioxidants | Mitochondria | Hospitals | Biopsy | Chronic obstructive pulmonary disease | Apoptosis | Smoking | NO, Nitric oxide | ΔΨm, Mitochondrial membrane potential | ASM, Airway smooth muscle | NAC, N-acetylcysteine | RL, Lung resistance | BAL, Bronchoalveolar lavage | OCR, Oxygen consumption rate | dTPP, Decyltriphenylphosphonium bromide | AHR, Airway hyperresponsiveness | logPC100, Concentration of acetylcholine that increased lung resistance by 100 | GOLD, Global Initiative for Chronic Obstructive Lung Disease | ATP, Adenosine triphosphate | KC, Keratinocyte-derived cytokine | JC-1, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide | COPD, Chronic obstructive pulmonary disease | ROS, Reactive oxygen species | Mechanisms of Allergy and Clinical Immunology
Journal Article
Journal Article
Journal of Dental Research, ISSN 0022-0345, 8/2013, Volume 92, Issue 8, pp. 735 - 739
Oxidative stress is associated with age-related reactions. The anti-oxidative effects of a reduced form of co-enzyme Q10 (rCoQ10) suppress oxidative stress,... 
coenzyme Q10 | aging | preclinical drug evaluation | inflammasomes | periodontium | oxidative stress | RAT PERIODONTITIS | MODEL | LEVEL | SALIVARY | DAMAGE | ANTIOXIDANT | INFLAMMATION | DENTISTRY, ORAL SURGERY & MEDICINE | STRESS | Interleukin-1beta - drug effects | Isoenzymes - analysis | Deoxyguanosine - blood | Age Factors | NLR Family, Pyrin Domain-Containing 3 Protein | Rats, Inbred F344 | Aging - drug effects | Tartrate-Resistant Acid Phosphatase | Alveolar Process - drug effects | Actins - drug effects | Male | Deoxyguanosine - analysis | Vitamins - pharmacology | Ubiquinone - pharmacology | Gingiva - pathology | Gingiva - drug effects | Inflammasomes - drug effects | Ubiquinone - blood | Electron Transport Chain Complex Proteins - pharmacology | Periodontium - pathology | Models, Animal | Periodontium - drug effects | Cytoskeletal Proteins - drug effects | Deoxyguanosine - analogs & derivatives | Carrier Proteins | DNA Damage - drug effects | Acid Phosphatase - analysis | Receptors, Cytoplasmic and Nuclear - drug effects | Ubiquinone - analogs & derivatives | Alveolar Process - pathology | Rats | Antioxidants - pharmacology | Random Allocation | Animals | Apoptosis Regulatory Proteins | Caspase 1 - drug effects | CARD Signaling Adaptor Proteins | Oxidative Stress - drug effects | Osteoclasts - drug effects | NF-kappa B - drug effects
Journal Article
Journal Article