X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1587) 1587
Publication (261) 261
Book Review (98) 98
Book Chapter (5) 5
Conference Proceeding (4) 4
Book / eBook (2) 2
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1548) 1548
humans (960) 960
animals (915) 915
ubiquitin thiolesterase - metabolism (770) 770
male (528) 528
ubiquitin thiolesterase (507) 507
biochemistry & molecular biology (434) 434
mice (427) 427
ubiquitin thiolesterase - genetics (407) 407
female (379) 379
ubiquitin (373) 373
immunohistochemistry (339) 339
neurosciences (337) 337
cell biology (315) 315
rats (283) 283
proteins (204) 204
ubiquitin - metabolism (201) 201
ubiquitination (199) 199
expression (195) 195
middle aged (157) 157
adult (153) 153
endopeptidases - metabolism (153) 153
enzymes (151) 151
cell line, tumor (150) 150
degradation (145) 145
thiolester hydrolases - metabolism (139) 139
thiolester hydrolases - analysis (136) 136
protein (133) 133
article (131) 131
rats, sprague-dawley (130) 130
research (128) 128
molecular sequence data (127) 127
ubiquitin-specific peptidase 7 (127) 127
analysis (123) 123
neurons (119) 119
aged (118) 118
cancer (118) 118
cells (117) 117
mutation (117) 117
protein binding (117) 117
cells, cultured (114) 114
hek293 cells (114) 114
cell line (113) 113
amino acid sequence (111) 111
innervation (108) 108
ubiquitin thiolesterase - physiology (108) 108
apoptosis (106) 106
signal transduction (106) 106
endopeptidases - genetics (104) 104
deubiquitinating enzymes (103) 103
hela cells (101) 101
rat (99) 99
gene expression (98) 98
pgp 9.5 (98) 98
phosphorylation (98) 98
ubiquitin thiolesterase - chemistry (94) 94
proteasome (93) 93
rats, wistar (93) 93
activation (91) 91
disease models, animal (91) 91
mice, inbred c57bl (90) 90
physiological aspects (90) 90
biophysics (89) 89
proteases (84) 84
time factors (84) 84
clinical neurology (82) 82
oncology (82) 82
proteasome endopeptidase complex - metabolism (82) 82
ubiquitin thiolesterase - antagonists & inhibitors (80) 80
deubiquitination (79) 79
nerve tissue proteins - metabolism (79) 79
deubiquitinating enzyme (78) 78
substance-p (77) 77
brain (76) 76
neurons - metabolism (75) 75
blotting, western (74) 74
gene (74) 74
genetic aspects (74) 74
mice, knockout (74) 74
physiology (73) 73
proteolysis (71) 71
pathway (70) 70
protein structure, tertiary (70) 70
research article (70) 70
abridged index medicus (69) 69
gene-related peptide (69) 69
skin - innervation (69) 69
nerve tissue proteins - analysis (67) 67
down-regulation (66) 66
parkinsons-disease (65) 65
uch-l1 (65) 65
calcitonin gene-related peptide - metabolism (61) 61
hydrolases (61) 61
nuclear proteins - metabolism (61) 61
protein gene product 9.5 (61) 61
ubiquitin-protein ligases - metabolism (61) 61
system (60) 60
endopeptidases - physiology (59) 59
nerve fibers - metabolism (59) 59
gene-expression (58) 58
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Genetics, ISSN 1061-4036, 12/2014, Volume 47, Issue 1, pp. 31 - 38
Cushing's disease is caused by corticotroph adenomas of the pituitary. To explore the molecular mechanisms of endocrine autonomy in these tumors, we performed... 
UBPY | ENDOSOMES | DOMAIN | PROTEIN | EPIDERMAL-GROWTH-FACTOR | GENETICS & HEREDITY | UBIQUITYLATION | DEGRADATION | RECEPTOR DOWN-REGULATION | ENDOCYTIC TRAFFICKING | PITUITARY-ADENOMAS | Adenoma - genetics | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Cercopithecus aethiops | Endosomal Sorting Complexes Required for Transport - genetics | Molecular Sequence Data | Pituitary Neoplasms - complications | ACTH-Secreting Pituitary Adenoma - complications | Pituitary ACTH Hypersecretion - genetics | ACTH-Secreting Pituitary Adenoma - genetics | Receptor, Epidermal Growth Factor - metabolism | Pituitary Neoplasms - secretion | Neoplasm Proteins - genetics | Pro-Opiomelanocortin - genetics | Amino Acid Sequence | ACTH-Secreting Pituitary Adenoma - metabolism | Pituitary Neoplasms - genetics | Ubiquitin Thiolesterase - physiology | Pituitary Neoplasms - metabolism | Ubiquitin Thiolesterase - genetics | 14-3-3 Proteins - metabolism | Adrenocorticotropic Hormone - secretion | Sequence Homology, Amino Acid | Exome - genetics | Sequence Alignment | Animals | Endopeptidases - genetics | ACTH-Secreting Pituitary Adenoma - secretion | Pro-Opiomelanocortin - biosynthesis | Mutation | COS Cells | Endosomal Sorting Complexes Required for Transport - physiology | Endopeptidases - physiology | Gene mutations | Cushing syndrome | Physiological aspects | Genetic aspects | Research | Ubiquitin-proteasome system | Health aspects | Risk factors | Pituitary gland | Kinases | Rodents | Genes | Tumors | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 04/2016, Volume 35, Issue 15, pp. 1996 - 2002
Germline BAP1 mutations predispose to several cancers, in particular malignant mesothelioma. Mesothelioma is an aggressive malignancy generally associated with... 
CANCER PATIENTS | SURVIVAL | CELLS | STRAND BREAK REPAIR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MALIGNANT PLEURAL MESOTHELIOMA | CROCIDOLITE ASBESTOS | CELL BIOLOGY | ONCOLOGY | GENETICS & HEREDITY | DEUBIQUITINASE BAP1 | TUMOR-ASSOCIATED MACROPHAGES | MUTATIONS | UBIQUITIN HYDROLASE | Leukocytes - pathology | Peritoneal Neoplasms - etiology | Cytokines - analysis | Male | Dose-Response Relationship, Drug | Peritonitis - genetics | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Ubiquitin Thiolesterase - deficiency | Germ-Line Mutation | Female | Peritonitis - etiology | Ascitic Fluid - chemistry | Genetic Predisposition to Disease | Macrophages, Peritoneal - physiology | Mice, Inbred C57BL | Asbestos, Crocidolite - administration & dosage | Mesothelioma - genetics | Ubiquitin Thiolesterase - physiology | Random Allocation | Ubiquitin Thiolesterase - genetics | Asbestos, Crocidolite - toxicity | Chemokines - analysis | Tumor Suppressor Proteins - physiology | Animals | Peritoneal Neoplasms - genetics | Macrophages, Peritoneal - classification | Mineral Fibers - toxicity | Heterozygote | Mice | Mesothelioma - etiology | Asbestos | Immune response | Gene mutations | Mesothelioma | Development and progression | Genetic aspects | Health aspects | Oncology | Mutation | Cytokines | Chemokines | Index Medicus | dose | macrophages | germline | asbestos | inflammation | BAP1 cancer syndrome | polarization | mesothelioma | BAP1
Journal Article
Oncogene, ISSN 0950-9232, 03/2010, Volume 29, Issue 9, pp. 1270 - 1279
Hausp is a deubiquitinase that has been shown to regulate the p53-Mdm2 pathway. Cotransfection of p53 and Hausp stabilizes p53 through the removal of ubiquitin... 
Mdm2 | Mouse | Hausp | Deubiquitination | Gene knockout | P53 | UBIQUITIN-SPECIFIC PROTEASE | P53-MDM2 PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | p53 | mdm2 | DEUBIQUITINATING ENZYMES | CELL BIOLOGY | gene knockout | mouse | REGULATOR | MDM2-DEFICIENT MICE | ONCOLOGY | GENETICS & HEREDITY | EMBRYONIC LETHALITY | deubiquitination | CONTRIBUTES | CARCINOMA | DOMAINS | hausp | USP7/HAUSP | Proto-Oncogene Proteins c-mdm2 - genetics | Humans | Ubiquitin - metabolism | Substrate Specificity | Tumor Suppressor Protein p53 - physiology | Genes, p53 - drug effects | Ubiquitin Thiolesterase - metabolism | Female | Proto-Oncogene Proteins c-mdm2 - metabolism | Ubiquitin Thiolesterase - antagonists & inhibitors | RNA Interference - immunology | Tumor Suppressor Proteins - metabolism | RNA, Small Interfering - pharmacology | Tumor Suppressor Protein p53 - metabolism | Ubiquitin-Protein Ligases - metabolism | Ubiquitin Thiolesterase - physiology | Genes, p53 - genetics | Ubiquitin Thiolesterase - genetics | Ubiquitin - physiology | Mice, Knockout | Animals | Genes, p53 - physiology | Cell Line, Tumor | Mice | Apoptosis - physiology | HeLa Cells | Ubiquitin-Specific Peptidase 7 | Post-translational modification | Proteases | Physiological aspects | Tumor suppressor genes | Genetic aspects | Research | Ubiquitin-proteasome system | Genetics | Oncology | Cellular biology | Ribonucleic acid--RNA | Rodents | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2012, Volume 441, Issue 3, pp. 979 - 986
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 46, pp. 16538 - 16543
Why different species are predisposed to different tumor spectra is not well understood. In particular, whether the physical location of tumor suppressor genes... 
Kidneys | Cysts | Renal cell carcinoma | Alleles | Tumor suppressor genes | Kidney cells | Lesions | Genetic mutation | Tumors | Cancer | HIF | MULTIDISCIPLINARY SCIENCES | HIPPEL-LINDAU-DISEASE | kidney stem cells | CELL CARCINOMA | LESIONS | kidney cancer | INACTIVATION | Six2-Cre | EVOLUTION | GENE | TUMOR-SUPPRESSOR | VHL | MUTATIONS | EXPRESSION | BAP1 | Kidney Neoplasms - genetics | Species Specificity | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Multipotent Stem Cells - metabolism | Carcinoma, Renal Cell - genetics | Male | Kidney Failure, Chronic - pathology | Tumor Suppressor Proteins - genetics | Kidney Diseases, Cystic - genetics | Female | Precancerous Conditions - pathology | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Von Hippel-Lindau Tumor Suppressor Protein - antagonists & inhibitors | Genes, Tumor Suppressor | Ubiquitin Thiolesterase - antagonists & inhibitors | Genes, Reporter | Disease Models, Animal | Genetic Predisposition to Disease | Mice, Inbred C57BL | Genes, Synthetic | Von Hippel-Lindau Tumor Suppressor Protein - physiology | Mice, Transgenic | Chromosome Mapping | Ubiquitin Thiolesterase - physiology | Ubiquitin Thiolesterase - genetics | Precancerous Conditions - genetics | Kidney Diseases, Cystic - pathology | Mice, Knockout | Kidney Failure, Chronic - genetics | Cell Lineage | Tumor Suppressor Proteins - physiology | Multipotent Stem Cells - pathology | Phenotype | Animals | Kidney Failure, Chronic - blood | Age of Onset | Mice | Models, Genetic | Mutation | Physiological aspects | Carcinoma | Kidney cancer | Rodents | Genes | Index Medicus | Biological Sciences
Journal Article
Blood, ISSN 0006-4971, 08/2013, Volume 122, Issue 5, pp. 715 - 725
Journal Article
Journal Article