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humans (346) 346
index medicus (297) 297
ubiquitin-specific peptidase 7 (242) 242
animals (151) 151
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ubiquitin (144) 144
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proto-oncogene proteins c-mdm2 - metabolism (36) 36
ubiquitin-specific proteases - genetics (36) 36
amino acid sequence (35) 35
endopeptidases - genetics (35) 35
health aspects (35) 35
ubiquitin thiolesterase - antagonists & inhibitors (35) 35
deubiquitinating enzymes (34) 34
gene expression regulation, neoplastic (34) 34
cell proliferation (33) 33
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Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 32, pp. 13296 - 13311
Sirtuin 7 (SIRT7), a member of theNAD(+)-dependent class III histone deacetylases, is involved in the regulation of various cellular processes and in resisting... 
RNA-POLYMERASE-I | SIRT7-DEPENDENT DEACETYLATION | HEPATOCELLULAR-CARCINOMA | ACTIVATION | TRANSCRIPTION FACTOR FOXO1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | DEPENDENT DEACETYLATION | HAUSP | EXPRESSION | P53 | Glucose-6-Phosphatase - genetics | ets-Domain Protein Elk-4 - genetics | Humans | Substrate Specificity | ets-Domain Protein Elk-4 - metabolism | Recombinant Fusion Proteins - metabolism | Protein Subunits - metabolism | Ubiquitination | RNA Interference | Gene Deletion | HEK293 Cells | Ubiquitin Thiolesterase - metabolism | Lysine - metabolism | Protein Interaction Domains and Motifs | Sirtuins - genetics | Peptide Fragments - genetics | Ubiquitin Thiolesterase - antagonists & inhibitors | Gluconeogenesis | Protein Subunits - genetics | Promoter Regions, Genetic | Peptide Fragments - metabolism | Recombinant Fusion Proteins - chemistry | Ubiquitin Thiolesterase - genetics | Glucose-6-Phosphatase - metabolism | Gene Expression Regulation, Enzymologic | Hydrolysis | Peptide Fragments - antagonists & inhibitors | Glucose-6-Phosphatase - antagonists & inhibitors | Cell Line, Tumor | Protein Processing, Post-Translational | Mutation | Sirtuins - antagonists & inhibitors | Sirtuins - metabolism | Ubiquitin-Specific Peptidase 7 | Amino Acid Substitution | Index Medicus | deubiquitylation (deubiquitination) | post-translational modification | sirtuin | gluconeogenesis | gene expression | Cell Biology
Journal Article
Academic Journal of Second Military Medical University, ISSN 0258-879X, 2016, Volume 37, Issue 8, pp. 986 - 991
Journal Article
Journal Article
Molecular medicine reports, 09/2015, Volume 12, Issue 3, p. 4652
Journal Article
Nature, ISSN 0028-0836, 10/2017, Volume 550, Issue 7677, pp. 534 - 538
The ubiquitin system regulates essential cellular processes in eukaryotes. Ubiquitin is ligated to substrate proteins as monomers or chains and the topology of... 
DEUBIQUITINATING ENZYME | MULTIDISCIPLINARY SCIENCES | LINKED UBIQUITIN | Pyridines - chemistry | Ubiquitin-Specific Peptidase 7 - chemistry | Humans | Ubiquitin - metabolism | Substrate Specificity | Tumor Suppressor Protein p53 - genetics | Aminopyridines - chemistry | Ubiquitin-Specific Peptidase 7 - deficiency | Proto-Oncogene Proteins c-pim-1 - antagonists & inhibitors | Female | Proto-Oncogene Proteins c-mdm2 - metabolism | Phenols - pharmacology | Binding, Competitive | Indazoles - chemistry | Tumor Suppressor Protein p53 - metabolism | Ubiquitin - chemistry | Models, Molecular | Neoplasms - enzymology | Ubiquitin-Specific Peptidase 7 - antagonists & inhibitors | Ubiquitin-Specific Peptidase 7 - metabolism | Mice, SCID | Tumor Suppressor Protein p53 - deficiency | Neoplasms - drug therapy | Drug Synergism | Indazoles - pharmacology | Animals | Aminopyridines - pharmacology | Cell Line, Tumor | Protein Binding | Phenols - chemistry | Mice | Pyridines - pharmacology | Neoplasms - pathology | Biological research | Physiological aspects | Chemical inhibitors | Research | Ubiquitin-proteasome system | Biology, Experimental | Ubiquitin | Nuclear magnetic resonance--NMR | Toxicity | Hydrogen | p53 Protein | Cytotoxicity | Chains | Kinases | Monomers | Proteins | Depolymerization | Eukaryotes | Ubiquitination | Cell cycle | Reaction kinetics | Catalysis | Crystal structure | Binding | Enzymes | Magnetic resonance | Topology | Substrates | Chemotherapy | Inhibitors | Cell death | Proteasomes | Resonance | Mutation | Kinetics | Cancer | Tumors
Journal Article
Neuron, ISSN 0896-6273, 06/2011, Volume 70, Issue 5, pp. 863 - 885
Journal Article
The FEBS Journal, ISSN 1742-464X, 03/2018, Volume 285, Issue 5, pp. 965 - 976
Transcription‐coupled nucleotide excision repair ( TC ‐ NER ) is a subpathway of nucleotide excision repair that efficiently removes transcription‐blocking DNA... 
UV‐stimulated scaffold protein A | ubiquitination | ubiquitin‐specific peptidase 7 | nucleotide excision repair | sensitive syndrome | UV-stimulated scaffold protein A | ubiquitin-specific peptidase 7 | UV-sensitive syndrome | PROTEIN-A | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFECT | COCKAYNE-SYNDROME | DAMAGE | COMPLEMENTATION GROUPS | CSA | XERODERMA-PIGMENTOSUM | DNA-REPAIR | GENE-PRODUCT | Amino Acid Sequence | Humans | Ubiquitin-Specific Peptidase 7 - antagonists & inhibitors | Mutation, Missense | Ubiquitin-Specific Peptidase 7 - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Sequence Homology, Amino Acid | Transcription Factors - metabolism | Point Mutation | Ubiquitin-Conjugating Enzymes - pharmacology | Phenotype | Sequence Alignment | Ubiquitination | Carrier Proteins - metabolism | Proteolysis | Ubiquitin-Conjugating Enzymes - metabolism | DNA Repair | Carrier Proteins - chemistry | Protein Interaction Domains and Motifs | Protein Processing, Post-Translational | Mutation | Proteasome Endopeptidase Complex - metabolism | Lysine - chemistry | Ubiquitin | Genetic transcription | DNA repair | DNA damage | Peptidase | Transcription | DNA polymerase | U.V. radiation | Hypersensitivity | Nucleotide excision repair | Protein A | Hereditary diseases | Degradation | Ultraviolet radiation | Lysine | Inhibition | Repair | Deoxyribonucleic acid--DNA
Journal Article
Nature Cell Biology, ISSN 1465-7392, 2014, Volume 16, Issue 9, pp. 864 - 875
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2017, Volume 114, Issue 14, pp. e2872 - e2881
Journal Article
Structure, ISSN 0969-2126, 01/2018, Volume 26, Issue 1, pp. 72 - 84.e7
Ubiquitin-specific protease 7 (USP7) deubiquitinase activity is controlled by a number of regulatory factors, including stimulation by intramolecular accessory... 
USP7 | protein engineering | deubiquinating enzymes | molecular dynamics | Rosetta | UBIQUITIN-SPECIFIC PROTEASE | SYSTEM | RECOGNITION | MECHANISM | STABILIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIMULATION | CELL BIOLOGY | POTENT | BIOPHYSICS | CHEMISTRY | INHIBITORS | USP7/HAUSP | Peptidomimetics - chemical synthesis | Ubiquitin-Specific Peptidase 7 - chemistry | Humans | Substrate Specificity | Crystallography, X-Ray | Enzyme Inhibitors - chemical synthesis | Thermodynamics | Enzyme Inhibitors - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Recombinant Proteins - metabolism | Amino Acid Sequence | Protein Conformation, alpha-Helical | Catalytic Domain | Gene Expression | Genetic Vectors - chemistry | Ubiquitin-Specific Peptidase 7 - genetics | Genetic Vectors - metabolism | Recombinant Proteins - chemistry | Peptidomimetics - chemistry | Recombinant Proteins - genetics | Ubiquitin-Specific Peptidase 7 - antagonists & inhibitors | Ubiquitin-Specific Peptidase 7 - metabolism | Static Electricity | Molecular Dynamics Simulation | Protein Conformation, beta-Strand | Escherichia coli - genetics | Hydrophobic and Hydrophilic Interactions | Protein Binding | Enzyme Activation | Kinetics | Mutation | Amino Acid Substitution | Ubiquitin | Cysteine | Proteases | Analysis | Crystals | Molecular dynamics | Structure
Journal Article